Mutagen X and chlorinated tap water are recombinagenic in yeast

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 563, Issue 2, 2004, Pages 159-169

  Egorov, Andrey I ^a,b   Howlett, Niall G ^a   Schiestl, Robert H ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DEL test; MX; Recombinations; Tap water

Indexed keywords

3 CHLORO 4 DICHLOROMETHYL 5 HYDROXY 2(5H) FURANONE; FURANONE DERIVATIVE; MUTAGENIC AGENT; TAP WATER; UNCLASSIFIED DRUG;

AMES TEST; ANEUPLOIDY; ARTICLE; CELL GROWTH; CHLORINATION; CHROMOSOME DELETION; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENETIC RECOMBINATION; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL;

ANEUPLOIDY; CHLORINE; CHROMOSOME DELETION; DISINFECTANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FURANS; GENOMIC INSTABILITY; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; WATER SUPPLY;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 4444339504     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.07.005     Document Type: Article

References (57)

1. R.D. Morris Drinking water and cancer. Review Environ. Health Perspect. 103 S. 8 1995 225 231
2. M. Koivusalo, and T. Vartiainen Drinking water chlorination by-products and cancer, Review Rev. Environ. Health 12 1997 81 90
3. M.L. Neuwenhuijsen, M.B. Toledano, N.E. Eaton, J. Fawell, and P. Eliott Chlorination disinfection byproducts an water and their association with adverse reproductive outcomes: a review Occup. Environ. Med. 57 2000 73 85
4. F. Bove, Y. Shim, and P. Zeitz Drinking water contaminants and adverse pregnancy outcomes: a review Environ. Health Perspect. 110 S. 1 2002 61 74
5. US Environmental Protection Agency, DBP Stage 2 Rule and Long-term 2 Enhanced Surface Water Treatment Rule: Draft Report on Research to Support Rules, 1997.
6. G. Boorman, V. Dellarco, J.K. Dunnic, R. Chapin, S. Hunter, F. Hauchman, H. Gardner, M. Cox, and R. Sills Drinking water disinfection by-products: review and approach to toxicity evaluation Environ. Health Perspect. 107 S. 1 1999 207 217
7. A. Smeds, T. Vartiainen, J. Maki-Paakkanen, and L. Kronberg Concentrations of Ames mutagenic chlorohydroxyfuranones and related compounds in drinking waters Environ. Sci. Technol. 31 1997 1033 1039
8. L. Kronberg, and T. Vartiainen Ames mutagenicity and concentration of the strong mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone and its geometric isomer E-2-chloro-3-(dichloromethyl)-4-oxo-butenoic acid in chlorine-treated waters Mutat. Res. 206 1988 177 182
9. D.M. DeMarini, A. Abu-Shakra, C.F. Felton, K.S. Patterson, and M.L. Shelton Mutation spectra in salmonella of chlorinated, chloraminated, or ozonated drinking water extracts: comparison to MX Environ. Mol. Mutagen. 26 1995 270 285
10. J.M. Wright, J. Schwartz, T. Vartiainen, J. Maki-Paakkanen, L. Altshul, J. Harrington, and D.W. Dockery 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)- furanone (MX) and mutagenicity in Massachusetts drinking water Environ. Health Perspect. 110 2002 157 164
11. Y. Kargalioglu, B.J. McMillan, R.A. Minear, and M.J. Plewa Analysis of the cytotoxicity and mutagenicity of drinking water disinfection by-products in Salmonella typhimurium Teratog. Carcinog. Mutagen. 22 2002 113 128
12. J.M. Hyttinen, and K. Jansson PM2 DNA damage induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2 (5H)-furanone (MX) Mutat. Res. 348 1995 183 186
13. J.M. Hyttinen, M. Niittykoski, and K. Jansson Lack of uniformity in the mutational spectra of chlorohydroxyfuranones in Salmonella typhimurium strain TA100 Mutagenesis 10 1995 321 323
14. R. Franzen, S. Goto, K. Tanade, and M. Morita Genotoxic activity of chlorinated butenoic acids in Salmonella typhimurium strains TA98, TA100 and TA104 Mutat. Res. 417 1998 31 37
15. D.M. DeMarini, S. Landi, T. Ohe, D.T. Shaughnessy, R. Franzen, and A.M. Richard Mutation spectra in Salmonella of analogues of MX: implications of chemical structure for mutational mechanisms Mutat. Res. 453 2000 51 65
16. K. Fecadu, W. Parzefall, L. Kronberg, R. Franzen, R. Schulte-Hermann, and S. Knasmuller Induction of genotoxic effects by chlorohydroxyfuranones, byproducts of water disinfection, in E. coli K-12 cells recovered from various organs in mice Environ. Mol. Mutagen. 24 1994 317 324
17. J.M. Hyttinen, S. Myohanen, and K. Jansson Kinds of mutations induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) hprt gene of Chinese hamster ovary cells Carcinogenesis 17 1996 1179 1181
18. K. Harrington-Brock, C.L. Doerr, and M.M. Moore Mutagenicity and clastogenicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in L5178Y/TK+/(-)-3.7.2C mouse lymphoma cells Mutat. Res. 348 1995 105 110
19. J.W. Nunn, and J.K. Chipman Induction of DNA strand breaks by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone and humic substances in relation to glutathione and calcium status in human white blood cells Mutat. Res. 341 1994 133 140
20. U. Marsteinstredet, G. Brunborg, M. Bjoras, E. Soderlund, E. Seeberg, L. Kronberg, and J.A. Holme DNA damage induced by 3-chloro-4-(dichloromethyl)-5- hydroxy-2[5H]-furanone (MX) in HL-60 cells and purified DNA in vitro Mutat. Res. 390 1997 171 178
21. J.W. Nunn, J.E. Davies, and J.K. Chipman Production of unscheduled DNA synthesis in rodent hepatocytes in vitro, but not in vivo, by 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) Mutat. Res. 373 1997 67 73
22. F. Le Curieux, F. Nesslany, T. Munter, L. Kronberg, and D. Marzin Genotoxic activity of chlorohydroxyfuranones in the microscale micronucleus test on mouse lymphoma cells and the unscheduled DNA synthesis assay in rat hepatocytes Mutagenesis 14 1999 457 462
23. J.A. Holme, U. Haddeland, K. Haug, and G. Brunborg DNA damage induced by the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in mammalian cells in vitro and in mice Mutat. Res. 441 1999 145 153
24. G. Brunborg, J.A. Holme, E.J. Soderlund, J.K. Hongslo, T. Vartiainen, S. Lotjonen, and G. Becher Genotoxic effects of the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) in mammalian cells in vitro and in rats in vivo Mutat. Res. 260 1991 55 64
25. K. Jansson, J. Maki-Paakkanen, S.L. Vaittinen, T. Vartiainen, H. Komulainen, and J. Tuomisto Cytogenetic effects of 3-chloro-4-(dichloromethyl)- 5-hydroxy-2(5H)-furanone (MX) in rat peripheral lymphocytes in vitro and in vivo Mutat. Res. 299 1993 25 28
26. J. Maki-Paakkanen, K. Jansson, and T. Vartiainen Induction of mutation, sister-chromatid exchanges, and chromosome aberrations by 3-chloro-4- (dichloromethyl)-5-hydroxy-2(5H)-furanone in Chinese hamster ovary cells Mutat. Res. 310 1994 117 123
27. M.J. Plewa, Y. Kargalioglu, D. Vankerk, R.A. Minear, and E.D. Wagner Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products Environ. Mol. Mutagen. 40 2002 134 142
28. N. Woodruff, J. Durant, L. Donhoffner, B. Penman, and C. Crespi Human cell mutagenicity of chlorinated and unchlorinated water and the disinfection by-product 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) Mutat. Res. 495 2001 157 168
29. F.B. Daniel, G.R. Olson, and J.A. Stober Induction of gastrointestinal tract nuclear anomalies in the B6C3F1 mice by 3-chloro-4-(dichloromethyl)-5- hydroxy-2(5H)-furanone and 3,4-(dichloro)-5-hydroxy-2(5H)-furanone, mutagenic by-products of chlorine disinfection Environ. Mol. Mutagen. 17 1991 32 39
30. Y.F. Sasaki, E. Nishidate, F. Izumiyama, M. Watanabe-Akanuma, N. Kinae, N. Matsusaka, and S. Tsuda Detection of in vivo genotoxicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) by the alkaline single cell gel electrophoresis (Comet) assay in multiple mouse organs Mutat. Res. 393 1997 47 53
31. H. Komulainen, V.M. Kosma, S.L. Vaittinen, T. Vartiainen, E. Kaliste-Korhonen, S. Lotjonen, R.K. Tuominen, and J. Tuomisto Carcinogenicity of the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in the rat J. Natl. Cancer Inst. 89 1997 848 856
32. M.J. Hooth, K.S. McDorman, S.D. Hester, M.H. George, L.R. Brooks, A.E. Swank, and D.C. Wolf The carcinogenic response of Tsc2 mutant Long-Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive Toxicol. Sci. 69 2002 322 331
33. K.S. McDorman, M.J. Hooth, T.B. Starr, and D.C. Wolf Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products Toxicology 187 2003 1 12
34. R.H. Schiestl Nonmutagenic carcinogens induce intrachromosomal recombination in yeast Nature 337 1989 285 288
35. R.H. Schiestl, W.S. Chan, R.D. Gietz, R.D. Mehta, and P.J. Hastings Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast Mutat. Res. 224 1989 427 436
36. R.H. Schiestl, and J.K. Reddy Effect of peroxisome proliferators on intrachromosomal and interchromosomal recombination in yeast Carcinogenesis 11 1990 173 176
37. R.H. Schiestl, R.D. Gietz, P.J. Hastings, and U. Wintersberger Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae Mol. Gen. Genet. 222 1990 25 32
38. N.G. Howlett, and R.H. Schiestl Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay Mutat. Res. 454 2000 53 62
39. R.H. Schiestl Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells Environ. Health Perspect. 101 S. 5 1993 179 185
40. A. Galli, and R.H. Schiestl Effects of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in G1-arrested yeast cells Mutat. Res. 370 1996 209 221
41. A. Galli, and R.H. Schiestl Effect of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in S-phase arrested yeast cells Mutat. Res. 419 1998 53 68
42. R.J. Brennan, and R.H. Schiestl Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae Mutat. Res. 397 1998 271 278
43. A.J. Bishop, and R.H. Schiestl Homologous recombination as a mechanism for genome rearrangements: environmental and genetic effects Human Mol. Genet. 9 2000 2427 2434
44. A.J. Bishop, and R.H. Schiestl Homologous recombination as a mechanism of carcinogenesis Biochim. Biophys. Acta 1471 2001 M109 M121 Review
45. A.J. Bishop, and R.H. Schiestl Role of homologous recombination in carcinogenesis Exp. Mol. Pathol. 74 2003 94 105 (Review)
46. M.J. Aardema, S. Albertini, P. Arni, L.M. Henderson, M. Kirsch-Volders, J.M. Mackay, A.M. Sariff, D.A. Stringer, and R.D. Taalman Aneuploidy: a report of an ECETOC task force Mutat. Res. 410 1998 3 79
47. A.I. Egorov, A. Tereschenko, L. Altshul, T. Vartiainen, D. Samsonov, B. LaBrecque, J. Mäki-Paakkanen, N. Drizhd, and T. Ford Exposures to drinking water chlorination by-products in a Russian city Int. J. Hygiene Environ. Health 206 6 2003 539 551
48. T. Vartiainen, A. Liimatainen, S. Jaaskelainen, and P. Kauranen Comparison of solvent extractions and resin adsorption for isolation of mutagenic compounds from chlorinated drinking water with high humus content Water Res. 21 1987 773 779
49. R.H. Schiestl, S. Igarashi, and P.J. Hastings Analysis of the mechanism for reversion of a disrupted gene Genetics 119 1988 237 247
50. J.M. Bland, and D.G. Altman Transformations, means, and confidence intervals BMJ 312 1996 1079
51. J.M. Bland, and D.G. Altman The use of transformation when comparing two means BMJ 312 1996 1153
52. W.N. Venables, and B.D. Ripley Modern Applied Statistics with S-Plus 1999 Springer-Verlag New York
53. E.N. Naumova, A. Must, and N.M. Laird Tutorial in biostatistics: evaluating the impact of 'critical periods' in longitudinal studies of growth using piecewise mixed effects models Int. J. Epidemiol. 30 2001 1332 1341
54. R.J. Brennan, and R.H. Schiestl Detecting carcinogens with the yeast DEL assay Methods Mol. Biol. 262 2004 111 124
55. R.H. Schiestl, J. Aubrecht, W.Y. Yap, S. Kandikonda, and S. Sidhom Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin induce intrachromosomal recombination in vitro and in vivo Cancer Res. 57 1997 4378 4383
56. N. Carls, and R.H. Schiestl Evaluation of the yeast DEL assay with 10 compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens Mutat. Res. 320 4 1994 293 303
57. T. Vartianen, and A. Liimatainen Relations between drinking water mutagenicity and water quality parameters Chemosphere 17 1988 189 202