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Volumn 107, Issue SUPPL. 1, 1999, Pages 207-217

Drinking water disinfection byproducts: Review and approach to toxicity evaluation

Author keywords

Alternate species; Animal studies; Carcinogenesis; Chloroform; Dibromoacetic acid; Dichloroacetic acid; Drinking water; Haloacetic acids; MX; Toxicology; Trichloroacetic acid; Trihalomethanes

Indexed keywords

ACETIC ACID DERIVATIVE; CARCINOGEN; CHLORINE; CHLORINE DIOXIDE; CHLOROFORM; CHLOROPICRIN; DISINFECTANT AGENT; DISINFECTION BYPRODUCT; DRINKING WATER; HALIDE; HALOACID; OZONE; TRICHLOROACETIC ACID; TRIHALOMETHANE; UNCLASSIFIED DRUG;

EID: 0032955294     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.99107s1207     Document Type: Review
Times cited : (376)

References (97)
  • 1
    • 0027048838 scopus 로고
    • Chlorination of drinking water and cancer, a review
    • Mughal FH. Chlorination of drinking water and cancer, a review. J Environ Pathol Toxicol Oncol 11:287-292 (1992).
    • (1992) J Environ Pathol Toxicol Oncol , vol.11 , pp. 287-292
    • Mughal, F.H.1
  • 4
    • 0003450446 scopus 로고
    • TR-321. Research Triangle Park, NC:National Toxicology Program
    • 1 Mice. TR-321. Research Triangle Park, NC:National Toxicology Program, 1987.
    • (1987) 1 Mice
  • 6
    • 0008613135 scopus 로고
    • TR-350. Research Triangle Park, NC:National Toxicology Program
    • 1 Mice (Gavage Studies). TR-350. Research Triangle Park, NC:National Toxicology Program, 1989.
    • (1989) 1 Mice (Gavage Studies)
  • 9
    • 0029909581 scopus 로고    scopus 로고
    • Case-control study of bladder cancer and chlorination byproducts in treated water
    • King WD, Marrett LD. Case-control study of bladder cancer and chlorination byproducts in treated water (Ontario, Canada). Cancer Causes Control 7:596-604 (1996).
    • (1996) Cancer Causes Control , vol.7 , pp. 596-604
    • King, W.D.1    Marrett, L.D.2
  • 10
    • 0029594503 scopus 로고
    • Drinking water and cancer
    • Morris RD. Drinking water and cancer. Environ Health Perspect 103:225-231 (1995)
    • (1995) Environ Health Perspect , vol.103 , pp. 225-231
    • Morris, R.D.1
  • 11
    • 0030807057 scopus 로고    scopus 로고
    • The association of drinking water source and chlorination byproducts with cancer incidence among post menopausal women in Iowa: A prospective cohort study
    • Doyle TJ, Zheng W, Cerhan JR, Hong CP, Sellers TA, Kushi LH, Folsom AR. The association of drinking water source and chlorination byproducts with cancer incidence among post menopausal women in Iowa: a prospective cohort study. Am J Public Health 87:1168-1176 (1997).
    • (1997) Am J Public Health , vol.87 , pp. 1168-1176
    • Doyle, T.J.1    Zheng, W.2    Cerhan, J.R.3    Hong, C.P.4    Sellers, T.A.5    Kushi, L.H.6    Folsom, A.R.7
  • 16
    • 0028855642 scopus 로고
    • Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells
    • Ballmaier D, Epe B. Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells. Carcinogenesis 16:335-342 (1995).
    • (1995) Carcinogenesis , vol.16 , pp. 335-342
    • Ballmaier, D.1    Epe, B.2
  • 17
    • 0031944826 scopus 로고    scopus 로고
    • Trihalomethanes in drinking water and spontaneous abortion
    • Waller K, Swan SH, DeLorenze G, Hopkins B. Trihalomethanes in drinking water and spontaneous abortion. Epidemiology 9:134-140 (1998).
    • (1998) Epidemiology , vol.9 , pp. 134-140
    • Waller, K.1    Swan, S.H.2    DeLorenze, G.3    Hopkins, B.4
  • 18
    • 0026712833 scopus 로고
    • The association of waterborne chloroform with intrauterine growth retardation
    • Kramer MD, Lynch CF, Isacson P, Hanson JW. The association of waterborne chloroform with intrauterine growth retardation. Epidemiology 3:407-413 (1992).
    • (1992) Epidemiology , vol.3 , pp. 407-413
    • Kramer, M.D.1    Lynch, C.F.2    Isacson, P.3    Hanson, J.W.4
  • 20
    • 0029146598 scopus 로고
    • Drinking water and pregnancy outcome in central North Carolina: Source, amount and trihalomethane levels
    • Savitz DA, Andrews KW, Pastore LM. Drinking water and pregnancy outcome in central North Carolina: source, amount and trihalomethane levels. Environ Health Perspect 103:592-596 (1995).
    • (1995) Environ Health Perspect , vol.103 , pp. 592-596
    • Savitz, D.A.1    Andrews, K.W.2    Pastore, L.M.3
  • 21
    • 0000305183 scopus 로고
    • Disinfectants and disinfection byproducts: Proposed rule
    • U.S. EPA. Disinfectants and disinfection byproducts: proposed rule. Fed Reg 59: 38668-38829 (1994).
    • (1994) Fed Reg , vol.59 , pp. 38668-38829
  • 22
    • 0000767372 scopus 로고
    • National interim primary drinking water regulations: Control of trihalomethanes in drinking water; final rule
    • U.S. EPA. National interim primary drinking water regulations: control of trihalomethanes in drinking water; final rule. Fed Reg 44: 68624-68707 (1979).
    • (1979) Fed Reg , vol.44 , pp. 68624-68707
  • 23
    • 84920311358 scopus 로고    scopus 로고
    • U.S. Congress. Public Health Service Act (Safe Drinking Water Act). Public Law 104-182, 104th Congress, 6 August 1996, 110 Stat 1613. Washington:U.S. Government Printing Office, 1996
    • U.S. Congress. Public Health Service Act (Safe Drinking Water Act). Public Law 104-182, 104th Congress, 6 August 1996, 110 Stat 1613. Washington:U.S. Government Printing Office, 1996.
  • 31
    • 0000931410 scopus 로고    scopus 로고
    • National drinking water regulations: Disinfectants and disinfection byproducts notice of data availability; proposed rule
    • U.S. EPA. National Drinking Water Regulations: Disinfectants and disinfection byproducts notice of data availability; proposed rule. Fed Reg 63:15674-15692 (1998).
    • (1998) Fed Reg , vol.63 , pp. 15674-15692
  • 33
    • 85044460298 scopus 로고
    • TR-282. Research Triangle Park, NC:National Toxicology Program
    • 1 Mice (Gavage Studies). TR-282. Research Triangle Park, NC:National Toxicology Program, 1985.
    • (1985) 1 Mice (Gavage Studies)
  • 34
    • 0023203541 scopus 로고
    • Bromodichloromethane, a trihalomethane that produces neoplasms in rodents
    • Dunnick JK, Eustis SL, Lilja HS. Bromodichloromethane, a trihalomethane that produces neoplasms in rodents. Cancer Res 47:5189-5193 (1987).
    • (1987) Cancer Res , vol.47 , pp. 5189-5193
    • Dunnick, J.K.1    Eustis, S.L.2    Lilja, H.S.3
  • 35
    • 84920311357 scopus 로고    scopus 로고
    • Unpublished data
    • Unpublished data.
  • 36
    • 0027324749 scopus 로고
    • Assessment of the carcinogenic potential of chlorinated water: Experimental studies of chlorine, chloramine, and trihalomethanes
    • Dunnick JK, Melnick RL. Assessment of the carcinogenic potential of chlorinated water: experimental studies of chlorine, chloramine, and trihalomethanes. J Natl Cancer Inst 85: 817-822 (1993).
    • (1993) J Natl Cancer Inst , vol.85 , pp. 817-822
    • Dunnick, J.K.1    Melnick, R.L.2
  • 39
    • 0023510171 scopus 로고
    • The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid in mouse liver
    • Herren-Freund SL, Pereira MA, Khoury MD, Olson G. The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid in mouse liver. Toxicol Appl Pharmacol 90:183-189 (1987).
    • (1987) Toxicol Appl Pharmacol , vol.90 , pp. 183-189
    • Herren-Freund, S.L.1    Pereira, M.A.2    Khoury, M.D.3    Olson, G.4
  • 40
    • 0030592952 scopus 로고    scopus 로고
    • The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat
    • DeAngelo AB, Daniel FB, Most BM, Olson GR. The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat. Toxicology 114:207-221 (1996).
    • (1996) Toxicology , vol.114 , pp. 207-221
    • DeAngelo, A.B.1    Daniel, F.B.2    Most, B.M.3    Olson, G.R.4
  • 41
    • 0030694391 scopus 로고    scopus 로고
    • Failure of monochloroacetic acid and trichloroacetic acid administered in the drinking water to produce liver cancer in male Fischer 344 rats
    • DeAngelo AB, Daniel FB, Most BM, Olson GR. Failure of monochloroacetic acid and trichloroacetic acid administered in the drinking water to produce liver cancer in male Fischer 344 rats. J Toxicol Environ Health 52:425-445 (1997).
    • (1997) J Toxicol Environ Health , vol.52 , pp. 425-445
    • DeAngelo, A.B.1    Daniel, F.B.2    Most, B.M.3    Olson, G.R.4
  • 43
    • 0029026852 scopus 로고
    • Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats
    • Richmond RE, Carter JH, Carter HW, Daniel FB, DeAngelo AB. Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats. Cancer Lett 92:67-76 (1995).
    • (1995) Cancer Lett , vol.92 , pp. 67-76
    • Richmond, R.E.1    Carter, J.H.2    Carter, H.W.3    Daniel, F.B.4    DeAngelo, A.B.5
  • 44
    • 26844575256 scopus 로고    scopus 로고
    • Lipid peroxidation and formation of 8-hydroxydeoxyguanosine from acute doses of halogenated acetic acids
    • Austin EW, Parrish JM, Kinder DH, Bull RJ. Lipid peroxidation and formation of 8-hydroxydeoxyguanosine from acute doses of halogenated acetic acids. Fundam Appl Toxicol 31:77-82 (1996).
    • (1996) Fundam Appl Toxicol , vol.31 , pp. 77-82
    • Austin, E.W.1    Parrish, J.M.2    Kinder, D.H.3    Bull, R.J.4
  • 46
    • 0029150242 scopus 로고
    • In vivo administration of dichloroacetic acid suppresses spontaneous apoptosis in murine hepatocytes
    • Snyder RD, Pullman J, Carter JH, Carter HW, DeAngelo AB. In vivo administration of dichloroacetic acid suppresses spontaneous apoptosis in murine hepatocytes. Cancer Res 55:3702-3705 (1995).
    • (1995) Cancer Res , vol.55 , pp. 3702-3705
    • Snyder, R.D.1    Pullman, J.2    Carter, J.H.3    Carter, H.W.4    DeAngelo, A.B.5
  • 47
    • 0028932625 scopus 로고
    • Modification of lipoperoxidative effects of dichloroacetate and trichloroacetate is associated with peroxisome proliferation
    • Austin EW, Okita JR, Okita RT, Larson JL, Bull RJ. Modification of lipoperoxidative effects of dichloroacetate and trichloroacetate is associated with peroxisome proliferation. Toxicology 97:59-69 (1995).
    • (1995) Toxicology , vol.97 , pp. 59-69
    • Austin, E.W.1    Okita, J.R.2    Okita, R.T.3    Larson, J.L.4    Bull, R.J.5
  • 50
    • 0001346268 scopus 로고
    • Detection, identification and quantitative analysis of dihatoacetonitriles in chlorinated natural waters
    • Keith LH, ed. Ann Arbor, MI:Ann Arbor Science
    • Trehy ML, Bieber TI. Detection, identification and quantitative analysis of dihatoacetonitriles in chlorinated natural waters. In: Advanced in the Identification and Analysis of Organic Pollutants in Water, Vol 2 (Keith LH, ed). Ann Arbor, MI:Ann Arbor Science, 1981:941-975.
    • (1981) Advanced in the Identification and Analysis of Organic Pollutants in Water , vol.2 , pp. 941-975
    • Trehy, M.L.1    Bieber, T.I.2
  • 52
    • 0028931773 scopus 로고
    • Study of the genotoxic activity of six halo-genated acetonitriles, using the SOS chromotest, the Ames-fluctuation test and the newt micronucleus test
    • Le Curieux F, Giller S, Gauthier L, Erb F, Marzin D. Study of the genotoxic activity of six halo-genated acetonitriles, using the SOS chromotest, the Ames-fluctuation test and the newt micronucleus test. Mutat Res 341:289-302 (1995).
    • (1995) Mutat Res , vol.341 , pp. 289-302
    • Le Curieux, F.1    Giller, S.2    Gauthier, L.3    Erb, F.4    Marzin, D.5
  • 53
    • 0022359627 scopus 로고
    • Evaluation of mutagenic and carcinogenic properties of brominated and chlorinated acetonitriles: Byproducts of chlorination
    • Bull RJ, Meier JR, Robinson M, Ringhand HP, Laurie RD, Stober JA. Evaluation of mutagenic and carcinogenic properties of brominated and chlorinated acetonitriles: byproducts of chlorination. Fundam Appl Toxicol 5:1065-1074 (1985).
    • (1985) Fundam Appl Toxicol , vol.5 , pp. 1065-1074
    • Bull, R.J.1    Meier, J.R.2    Robinson, M.3    Ringhand, H.P.4    Laurie, R.D.5    Stober, J.A.6
  • 57
    • 0038807791 scopus 로고
    • Treatment for the control of disinfection residuals and disinfection byproducts
    • Craun GF, ed. Washington:International Life Sciences Institute Press
    • Trussell RR. Treatment for the control of disinfection residuals and disinfection byproducts. In: Safety of Water Disinfection: Balancing Chemical and Microbial Risks (Craun GF, ed). Washington:International Life Sciences Institute Press, 1993:319-343.
    • (1993) Safety of Water Disinfection: Balancing Chemical and Microbial Risks , pp. 319-343
    • Trussell, R.R.1
  • 58
    • 0025987125 scopus 로고
    • Analysis of ozonation byproducts produced in drinking water treatment
    • Koga M, Akiyama T, Glaze WH. Analysis of ozonation byproducts produced in drinking water treatment. Toxicol Ind Health 7:423-432 (1991).
    • (1991) Toxicol Ind Health , vol.7 , pp. 423-432
    • Koga, M.1    Akiyama, T.2    Glaze, W.H.3
  • 59
    • 0142172891 scopus 로고
    • Occurrence and exposures to disinfectants and disinfection byproducts
    • Craun GF, ed. Washington:International Life Sciences Institute Press
    • Cumming RB, Jolley RL. Occurrence and exposures to disinfectants and disinfection byproducts. In: Safety of Water Disinfection: Balancing Chemical and Microbial Risks (Craun GF, ed). Washington:International Life Sciences Institute Press, 1993:257-275.
    • (1993) Safety of Water Disinfection: Balancing Chemical and Microbial Risks , pp. 257-275
    • Cumming, R.B.1    Jolley, R.L.2
  • 61
    • 0024564662 scopus 로고
    • Chronic toxicity study on formaldehyde administered orally to rats
    • Tobe M, Naito K, Kurokawa Y. Chronic toxicity study on formaldehyde administered orally to rats. Toxicology 56:79-86 (1989).
    • (1989) Toxicology , vol.56 , pp. 79-86
    • Tobe, M.1    Naito, K.2    Kurokawa, Y.3
  • 62
    • 0031661644 scopus 로고    scopus 로고
    • The carcinogenicity of potassium bromate in the male Fischer 344 rats
    • DeAngelo AB, Daniel FB, Most BM, Olson GR. The carcinogenicity of potassium bromate in the male Fischer 344 rats. Toxicol Pathol 26: 587-594 (1998).
    • (1998) Toxicol Pathol , vol.26 , pp. 587-594
    • DeAngelo, A.B.1    Daniel, F.B.2    Most, B.M.3    Olson, G.R.4
  • 64
    • 0031443451 scopus 로고    scopus 로고
    • Carcinogenic activity of the flame retardant, 2,2-bis(bromomethyl)-1,3-propanediol in rodents, and comparison with the carcinogenicity of other NTP brominated chemicals
    • Dunnick JK, Heath JE, Farnell DR, Prejean JD, Haseman JK, Elwell MR. Carcinogenic activity of the flame retardant, 2,2-bis(bromomethyl)-1,3-propanediol in rodents, and comparison with the carcinogenicity of other NTP brominated chemicals. Toxicol Pathol 25:541-548 (1997).
    • (1997) Toxicol Pathol , vol.25 , pp. 541-548
    • Dunnick, J.K.1    Heath, J.E.2    Farnell, D.R.3    Prejean, J.D.4    Haseman, J.K.5    Elwell, M.R.6
  • 65
    • 0031935131 scopus 로고    scopus 로고
    • Mechanisms of chemically induced renal carcinogenesis in the laboratory rodent
    • Hard GC. Mechanisms of chemically induced renal carcinogenesis in the laboratory rodent. Toxicol Pathol 26:104-112 (1998).
    • (1998) Toxicol Pathol , vol.26 , pp. 104-112
    • Hard, G.C.1
  • 66
    • 0023637475 scopus 로고
    • Oral administration of the renal carcinogen, potassium bromate, specifically produces 8-hydroxydeoxyguanosine in rat target organ DNA
    • Kasai H, Nishimura S, Kurokawa Y, Hayashi Y. Oral administration of the renal carcinogen, potassium bromate, specifically produces 8-hydroxydeoxyguanosine in rat target organ DNA. Carcinogenesis 8:1959-1961 (1987).
    • (1987) Carcinogenesis , vol.8 , pp. 1959-1961
    • Kasai, H.1    Nishimura, S.2    Kurokawa, Y.3    Hayashi, Y.4
  • 67
    • 0026065352 scopus 로고
    • Relation of 8-hydroxydeoxyguanosine formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromate
    • Sai K, Takagi A, Umemura T, Hasegawa R, Kurokawa Y. Relation of 8-hydroxydeoxyguanosine formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromate. Jpn J Cancer Res 82:165-169 (1991).
    • (1991) Jpn J Cancer Res , vol.82 , pp. 165-169
    • Sai, K.1    Takagi, A.2    Umemura, T.3    Hasegawa, R.4    Kurokawa, Y.5
  • 69
    • 0008489116 scopus 로고
    • Formation and characterization of disinfection byproducts
    • Craun GF, ed. Washington:International Life Sciences Institute Press
    • Singer PC. Formation and characterization of disinfection byproducts. In: Safety of Water Disinfection: Balancing Chemical and Microbial Risks (Craun GF, ed). Washington:International Life Sciences Institute Press, 1993;201-220.
    • (1993) Safety of Water Disinfection: Balancing Chemical and Microbial Risks , pp. 201-220
    • Singer, P.C.1
  • 71
    • 77957186700 scopus 로고
    • 1 mice. Comparison of administration by gavage in corn oil vs. ad libitum in drinking water
    • 1 mice. Comparison of administration by gavage in corn oil vs. ad libitum in drinking water. Fundam Appl Toxicol 22:90-102 (1994).
    • (1994) Fundam Appl Toxicol , vol.22 , pp. 90-102
    • Larson, J.L.1    Wolf, D.C.2    Butterworth, B.E.3
  • 72
    • 0028892461 scopus 로고
    • Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models
    • Tennant RW, French JE, Spalding JW. Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models. Environ Health Perspect 103:942-950 (1995).
    • (1995) Environ Health Perspect , vol.103 , pp. 942-950
    • Tennant, R.W.1    French, J.E.2    Spalding, J.W.3
  • 74
    • 0027428688 scopus 로고
    • Case-control study of bladder cancer and water disinfection methods in Colorado
    • McGeehin MA, Reif JS, Becher JC, Mangione EJ. Case-control study of bladder cancer and water disinfection methods in Colorado. Am J Epidemiol 138:492-501 (1993).
    • (1993) Am J Epidemiol , vol.138 , pp. 492-501
    • McGeehin, M.A.1    Reif, J.S.2    Becher, J.C.3    Mangione, E.J.4
  • 76
    • 0031417343 scopus 로고    scopus 로고
    • Short-term carcinogenicity testing of a potent murine intestinal mutagen, 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhlP) in Apc 1638N transgenic mice
    • Sorensen IK, Kristiansen E, Mortensen A, van Kranen H, van Kreijl C, Fodde R, Thorgeirsson SS. Short-term carcinogenicity testing of a potent murine intestinal mutagen, 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhlP) in Apc 1638N transgenic mice. Carcinogenesis 18:777-781 (1997).
    • (1997) Carcinogenesis , vol.18 , pp. 777-781
    • Sorensen, I.K.1    Kristiansen, E.2    Mortensen, A.3    Van Kranen, H.4    Van Kreijl, C.5    Fodde, R.6    Thorgeirsson, S.S.7
  • 77
    • 0027299784 scopus 로고
    • Aquatic toxicology. Past, present and prospects
    • Pritchard J. Aquatic toxicology. Past, present and prospects. Environ Health Perspect 100:249-257 (1993).
    • (1993) Environ Health Perspect , vol.100 , pp. 249-257
    • Pritchard, J.1
  • 78
    • 0021952603 scopus 로고
    • Development of aquarium fish models for environmental carcinogenesis. Tumor induction in seven species
    • Hawkins WE, Overstreet RM, Fournie JW, Walker WW. Development of aquarium fish models for environmental carcinogenesis. Tumor induction in seven species. J Appl Toxicol 5:261-264 (1985).
    • (1985) J Appl Toxicol , vol.5 , pp. 261-264
    • Hawkins, W.E.1    Overstreet, R.M.2    Fournie, J.W.3    Walker, W.W.4
  • 79
    • 0030953477 scopus 로고    scopus 로고
    • Diagnostic criteria for degenerative, inflammatory, proliferate nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): Consensus of a national toxicology program pathology working group
    • Boorman GA, Botts S, Bunton TE, Fournie JW, Harshbarger JC, Hawkins WE, Hinton DE, Jokinen MP, Okihiro MS, Wolfe MJ. Diagnostic criteria for degenerative, inflammatory, proliferate nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): consensus of a National Toxicology Program pathology working group. Toxicol Pathol 25:202-210 (1997).
    • (1997) Toxicol Pathol , vol.25 , pp. 202-210
    • Boorman, G.A.1    Botts, S.2    Bunton, T.E.3    Fournie, J.W.4    Harshbarger, J.C.5    Hawkins, W.E.6    Hinton, D.E.7    Jokinen, M.P.8    Okihiro, M.S.9    Wolfe, M.J.10
  • 80
    • 0030788139 scopus 로고    scopus 로고
    • The use of non-traditional assays in an integrated environmental assessment of contaminated groundwater
    • Twerdok LE, Burton DT, Gardner HS, Shedd TR, Wolfe MJ. The use of non-traditional assays in an integrated environmental assessment of contaminated groundwater. Environ Toxicol Chem 16:1816-1820 (1997).
    • (1997) Environ Toxicol Chem , vol.16 , pp. 1816-1820
    • Twerdok, L.E.1    Burton, D.T.2    Gardner, H.S.3    Shedd, T.R.4    Wolfe, M.J.5
  • 81
    • 0021927001 scopus 로고
    • Development of aquarium fish models for environmental carcinogenesis: An intermittent-flow exposure system for volatile, hydrophobic chemicals
    • Walker WW, Manning CS, Overstreet RM, Hawkins WE. Development of aquarium fish models for environmental carcinogenesis: an intermittent-flow exposure system for volatile, hydrophobic chemicals. J Appl Toxicol 5:255-260 (1985).
    • (1985) J Appl Toxicol , vol.5 , pp. 255-260
    • Walker, W.W.1    Manning, C.S.2    Overstreet, R.M.3    Hawkins, W.E.4
  • 82
    • 0028971534 scopus 로고
    • Modeling response of species to microcontaminants: Comparative ecotoxicology by (sub)lethal body burdens as function of species size and partition ratio of chemicals
    • Hendriks AJ. Modeling response of species to microcontaminants: comparative ecotoxicology by (sub)lethal body burdens as function of species size and partition ratio of chemicals. Ecotoxicol Environ Saf 32:103-130 (1995).
    • (1995) Ecotoxicol Environ Saf , vol.32 , pp. 103-130
    • Hendriks, A.J.1
  • 83
    • 0016686113 scopus 로고
    • Histologic and electron microscopy observations on diethylnitrosamine-indiced hepatomas in small aquarium fish (Oryzias latipes)
    • Ishikawa T, Shimamine T, Takayama S. Histologic and electron microscopy observations on diethylnitrosamine-indiced hepatomas in small aquarium fish (Oryzias latipes). J Natl Cancer Inst 55:909-916 (1975).
    • (1975) J Natl Cancer Inst , vol.55 , pp. 909-916
    • Ishikawa, T.1    Shimamine, T.2    Takayama, S.3
  • 84
    • 0028997285 scopus 로고
    • A molecular approach to cancer risk
    • Stone R. A molecular approach to cancer risk. Science 268:356-357 (1995).
    • (1995) Science , vol.268 , pp. 356-357
    • Stone, R.1
  • 85
    • 0023430918 scopus 로고
    • A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered foci
    • Pitot HC, Goldsworthy TL, Moran S, Kennan W, Glauert HP. A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered foci. Carcinogenesis 8:1491-1499 (1987).
    • (1987) Carcinogenesis , vol.8 , pp. 1491-1499
    • Pitot, H.C.1    Goldsworthy, T.L.2    Moran, S.3    Kennan, W.4    Glauert, H.P.5
  • 86
    • 0019810501 scopus 로고
    • Dose response studies of carcinogenesis in rats by nitrosodiethylamine
    • Lijinsky W, Reuber MD, Riggs CW. Dose response studies of carcinogenesis in rats by nitrosodiethylamine. Cancer Res 41:4997-5003 (1981).
    • (1981) Cancer Res , vol.41 , pp. 4997-5003
    • Lijinsky, W.1    Reuber, M.D.2    Riggs, C.W.3
  • 87
    • 0025074980 scopus 로고
    • Cytotoxicity phase of dietheylnitrosamine-induced hepatic neoplasia in medaka
    • Lauren DJ, Teh SJ, Hinton DE. Cytotoxicity phase of dietheylnitrosamine-induced hepatic neoplasia in medaka. Cancer Res 50:5504-5514 (1990).
    • (1990) Cancer Res , vol.50 , pp. 5504-5514
    • Lauren, D.J.1    Teh, S.J.2    Hinton, D.E.3
  • 88
    • 0024952639 scopus 로고
    • Diethylnitrosamine (DEN)-induced degenerative, proliferate and neoplastic lesions in the liver of the medaka (Oryzias latipes) following short-term exposure
    • Burton TE. Diethylnitrosamine (DEN)-induced degenerative, proliferate and neoplastic lesions in the liver of the medaka (Oryzias latipes) following short-term exposure. Mar Environ Res 28:369-374 (1989).
    • (1989) Mar Environ Res , vol.28 , pp. 369-374
    • Burton, T.E.1
  • 89
    • 84920311355 scopus 로고    scopus 로고
    • Papa L. Personal communication
    • Papa L. Personal communication.
  • 90
    • 0031059392 scopus 로고    scopus 로고
    • Clonality of dysplastic epithelium in colorectal adenomas from familial adenomalous polyposis patients
    • Bjerknes M, Cheng H, Kim H, Schnitzler M, Gallinger S. Clonality of dysplastic epithelium in colorectal adenomas from familial adenomalous polyposis patients. Cancer Res 57: 355-361 (1997).
    • (1997) Cancer Res , vol.57 , pp. 355-361
    • Bjerknes, M.1    Cheng, H.2    Kim, H.3    Schnitzler, M.4    Gallinger, S.5
  • 91
  • 92
    • 0004155434 scopus 로고
    • Washington:National Academy Press
    • National Research Council. Issues in Risk Assessment. Washington:National Academy Press, 1993.
    • (1993) Issues in Risk Assessment
  • 94
    • 0025415225 scopus 로고
    • Chlorination byproducts in drinking water: From formation potentials to finished water concentrations
    • Reckhow DA, Singer PC. Chlorination byproducts in drinking water: from formation potentials to finished water concentrations. J Am Water Works Assoc 82:173-179 (1990).
    • (1990) J Am Water Works Assoc , vol.82 , pp. 173-179
    • Reckhow, D.A.1    Singer, P.C.2
  • 95
    • 0026154150 scopus 로고
    • Applying oxone for organics control and disinfection: A utility perspective
    • Ferguson DW, Gramith JT, McGuire MJ. Applying oxone for organics control and disinfection: a utility perspective. J Am Water Works Assoc 83:32-41 (1991).
    • (1991) J Am Water Works Assoc , vol.83 , pp. 32-41
    • Ferguson, D.W.1    Gramith, J.T.2    McGuire, M.J.3
  • 96
    • 84920311354 scopus 로고    scopus 로고
    • U.S. EPA. EPA Contract No 68-C6-0059, Work Assignment 0-05, SAIC Project No 01-0833-07-8979-400, 10 October 1997. Washington:U.S. Environmental Protection Agency, 1997
    • U.S. EPA. EPA Contract No 68-C6-0059, Work Assignment 0-05, SAIC Project No 01-0833-07-8979-400), 10 October 1997. Washington:U.S. Environmental Protection Agency, 1997.
  • 97
    • 0004126945 scopus 로고
    • TR-392. Research Triangle Park, NC:National Toxicology Program
    • 1 Mice (Drinking Water Studies). TR-392. Research Triangle Park, NC:National Toxicology Program, 1992.
    • (1992) 1 Mice (Drinking Water Studies)


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