Human cell mutagenicity of chlorinated and unchlorinated water and the disinfection byproduct 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 495, Issue 1-2, 2001, Pages 157-168

  Woodruff, Nathaniel W ^a   Durant, John L ^a   Donhoffner, Lawrence L ^b   Penman, Bruce W ^c   Crespi, Charles L ^b  

^a Tufts University   (United States)

^b Gentest Corporation   (United States)

^c NONE

Author keywords

3 Chloro 4 (dichloromethyl) 5 hydroxy 2(5H) furanone (MX); Chlorinated water; Chlorination byproducts; Human cells; Mutagenicity; Unchlorinated water

Indexed keywords

3 CHLORO 4 DICHLOROMETHYL 5 HYDROXY 2(5H) FURANONE; CYTOCHROME P450; DRINKING WATER; EPOXIDE HYDROLASE; FURANONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL SURVIVAL; CHLORINATION; CYTOGENETICS; DISINFECTION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MUTAGENIC ACTIVITY; MUTAGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOTAL ORGANIC CARBON; WATER SAMPLING;

B-LYMPHOCYTES; CELL LINE; CHLORINE; CYTOCHROME P-450 ENZYME SYSTEM; DISINFECTANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXIDE HYDROLASES; FURANS; HUMANS; HUMIC SUBSTANCES; MUTAGENICITY TESTS; MUTAGENS; POINT MUTATION; THYMIDINE KINASE; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION; WATER SUPPLY;

EID: 0035934449     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(01)00243-1     Document Type: Article

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