Roles of histidine 784 and tyrosine 639 in ribose discrimination by T7 RNA polymerase

Biochemistry

Volumn 39, Issue 5, 2000, Pages 919-923

  Brieba, Luis G ^a   Sousa, Rui ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DNA POLYMERASE; GLUTAMIC ACID; HISTIDINE DERIVATIVE; HYDROXYL GROUP; PHENYLALANINE; RIBONUCLEOTIDE; RIBOSE; RNA POLYMERASE; TYROSINE DERIVATIVE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HYDROGEN BOND; MUTATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BACTERIOPHAGE T7; DEOXYRIBONUCLEOTIDES; DNA-DIRECTED RNA POLYMERASES; ENZYME ACTIVATION; HISTIDINE; KINETICS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RIBOSE; TRANSCRIPTION, GENETIC; TYROSINE; VIRAL PROTEINS;

EID: 0034620583     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992324+     Document Type: Article

References (17)

1. Gao, G., Orlova, M., Georgiadis, M. M., Hendrickson, W. A., and Goff, S. P. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 407-411.
2. Astatke, M., Ng, K., Grindley, N. D. F., and Joyce, C. M. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 3402-3407.
3. Joyce, C. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 1619-1622.
4. Cheetham, G. M. T., Jeruzalmi, D., and Steitz, T. A. (1999) Nature 399, 80-83.
5. Sousa, R., and Padilla, R. (1995) EMBO J. 14, 4609-4621.
6. Huang, Y., Eckstein, F., Padilla, R., and Sousa, R. (1997) Biochemistry 36, 8231-8242.
7. Huang, Y., Beaudry, A., McSwiggen, J., and Sousa, R. (1997) Biochemistry 36, 13718-13728.
8. Villemain, J., Guajardo, R., and Sousa, R. (1997) J. Mol. Biol. 273, 958-977.
9. McAllister, W. T. (1993) Mol. Microbiol. 10, 1-6.
10. Li, Y., Korolev, S., and Waksman, G. (1998) EMBO J. 17, 7514-7525.
11. Bonner, G., Patra, D., Lafer, E. M., and Sousa, R. (1992) EMBO J. 11, 3767-3775.
12. Bonner, G., Lafer, E. M., and Sousa, R. (1994) J. Biol. Chem. 42, 25120-25128.
13. Padilla, R., and Sousa, R. (1999) Nucleic Acids Res. 27, 1561-1563.
14. Doublie, S., Tabor, S., Long, A. M., Richardson, C. C., and Ellenberger, T. (1998) Nature 391, 251-258.
15. Polesky, A. H., Dahlberg, M. E., Benkovic, S. J., Grindley, N. D. F., and Joyce, C. M. (1992) J. Biol. Chem. 267, 8417-8428.
16. Minnick, D. T., Bebenek, K., Osheroff, W. P., Turner, R. M., Jr., Astatke, M., Liu, L., Kunkel, T. A., and Joyce, C. M. (1999) J. Biol. Chem. 274, 3067-3075.
17. Martin, C. T., Muller, D. K., and Coleman, J. E. (1988) Biochemistry 27, 3966-3974.