What affects the effect of 2'-alkoxy modifications? 1. Stabilization effect of 2'-methoxy substitutions in uniformly modified DNA oligonucleotides

Biochemistry

Volumn 37, Issue 19, 1998, Pages 6991-6997

  Lesnik, Elena A ^a   Freier, Susan M ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYADENOSINE; DEOXYURIDINE; DNA; DNA HYBRID; DOUBLE STRANDED DNA; OLIGONUCLEOTIDE; PYRIMIDINE DERIVATIVE;

ARTICLE; DNA CONFORMATION; DNA MODIFICATION; DNA RNA HYBRIDIZATION; DNA SEQUENCE; HYDROPHOBICITY; MOLECULAR STABILITY; PRIORITY JOURNAL; RNA RNA HYBRIDIZATION; THERMODYNAMICS; THERMOSTABILITY;

CIRCULAR DICHROISM; DNA; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; PURINE NUCLEOTIDES; PYRIMIDINE NUCLEOTIDES; THERMODYNAMICS; THIONUCLEOTIDES;

EID: 0032510712     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972995c     Document Type: Article

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