-
1
-
-
0037378951
-
Resistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cells
-
I. Aguilar-Delfin P.J. Wettstein D.H. Persing Resistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cells Infect. Immun. 71 2003 2002 2008
-
(2003)
Infect. Immun.
, vol.71
, pp. 2002-2008
-
-
Aguilar-Delfin, I.1
Wettstein, P.J.2
Persing, D.H.3
-
2
-
-
33745825965
-
IL-23 neutralization protects mice from Gram-negative endotoxic shock
-
M.L. Belladonna C. Vacca C. Volpi A. Giampietri M.C. Fioretti P. Puccetti U. Grohmann F. Campanile IL-23 neutralization protects mice from Gram-negative endotoxic shock Cytokine 34 2006 161 169
-
(2006)
Cytokine
, vol.34
, pp. 161-169
-
-
Belladonna, M.L.1
Vacca, C.2
Volpi, C.3
Giampietri, A.4
Fioretti, M.C.5
Puccetti, P.6
Grohmann, U.7
Campanile, F.8
-
3
-
-
0038709564
-
Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens
-
A. Bot E. Rodrigo T. Wolfe S. Bot M.G. Von Herrath Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens J. Virol. 77 2003 5794 5800
-
(2003)
J. Virol.
, vol.77
, pp. 5794-5800
-
-
Bot, A.1
Rodrigo, E.2
Wolfe, T.3
Bot, S.4
Von Herrath, M.G.5
-
4
-
-
4444279595
-
Molecular epidemiology of Pseudomonas aeruginosa, Burkholderia cepacia complex and methicillin-resistant Staphylococcus aureus in a cystic fibrosis center
-
S. Campana G. Taccetti N. Ravenni I. Masi S. Audino B. Sisi T. Repetto G. Doring M. de Martino Molecular epidemiology of Pseudomonas aeruginosa , Burkholderia cepacia complex and methicillin-resistant Staphylococcus aureus in a cystic fibrosis center J. Cyst. Fibros. 3 2004 159 163
-
(2004)
J. Cyst. Fibros.
, vol.3
, pp. 159-163
-
-
Campana, S.1
Taccetti, G.2
Ravenni, N.3
Masi, I.4
Audino, S.5
Sisi, B.6
Repetto, T.7
Doring, G.8
de Martino, M.9
-
5
-
-
0030469719
-
Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
-
S.S. Cho C.M. Bacon C. Sudarshan R.C. Rees D. Finbloom R. Pine J.J. O’Shea Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation J. Immunol. 157 1996 4781 4789
-
(1996)
J. Immunol.
, vol.157
, pp. 4781-4789
-
-
Cho, S.S.1
Bacon, C.M.2
Sudarshan, C.3
Rees, R.C.4
Finbloom, D.5
Pine, R.6
O’Shea, J.J.7
-
6
-
-
0036467445
-
Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present
-
A.M. Cooper A. Kipnis J. Turner J. Magram J. Ferrante I.M. Orme Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present J. Immunol. 168 2002 1322 1327
-
(2002)
J. Immunol.
, vol.168
, pp. 1322-1327
-
-
Cooper, A.M.1
Kipnis, A.2
Turner, J.3
Magram, J.4
Ferrante, J.5
Orme, I.M.6
-
8
-
-
0031707741
-
Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans
-
K. Decken G. Kohler K. Palmer-Lehmann A. Wunderlin F. Mattner J. Magram M.K. Gately G. Alber Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans Infect. Immun. 66 1998 4994 5000
-
(1998)
Infect. Immun.
, vol.66
, pp. 4994-5000
-
-
Decken, K.1
Kohler, G.2
Palmer-Lehmann, K.3
Wunderlin, A.4
Mattner, F.5
Magram, J.6
Gately, M.K.7
Alber, G.8
-
10
-
-
0033588250
-
Urokinase induces activation and formation of Stat4 and Stat1–Stat2 complexes in human vascular smooth muscle cells
-
I. Dumler A. Kopmann K. Wagner O.A. Mayboroda U. Jerke R. Dietz H. Haller D.C. Gulba Urokinase induces activation and formation of Stat4 and Stat1–Stat2 complexes in human vascular smooth muscle cells J. Biol. Chem. 274 1999 24059 24065
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24059-24065
-
-
Dumler, I.1
Kopmann, A.2
Wagner, K.3
Mayboroda, O.A.4
Jerke, U.5
Dietz, R.6
Haller, H.7
Gulba, D.C.8
-
11
-
-
0036127059
-
In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70
-
K.L. Elkins A. Cooper S.M. Colombini S.C. Cowley T.L. Kieffer In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70 Infect. Immun. 70 2002 1936 1948
-
(2002)
Infect. Immun.
, vol.70
, pp. 1936-1948
-
-
Elkins, K.L.1
Cooper, A.2
Colombini, S.M.3
Cowley, S.C.4
Kieffer, T.L.5
-
12
-
-
0034254823
-
Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection
-
M.R. Gyetko S. Sud T. Kendall J.A. Fuller M.W. Newstead T.J. Standiford Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection J. Immunol. 165 2000 1513 1519
-
(2000)
J. Immunol.
, vol.165
, pp. 1513-1519
-
-
Gyetko, M.R.1
Sud, S.2
Kendall, T.3
Fuller, J.A.4
Newstead, M.W.5
Standiford, T.J.6
-
13
-
-
0242584872
-
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection
-
K.I. Happel M. Zheng E. Young L.J. Quinton E. Lockhart A.J. Ramsay J.E. Shellito J.R. Schurr G.J. Bagby S. Nelson J.K. Kolls Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection J. Immunol. 170 2003 4432 4436
-
(2003)
J. Immunol.
, vol.170
, pp. 4432-4436
-
-
Happel, K.I.1
Zheng, M.2
Young, E.3
Quinton, L.J.4
Lockhart, E.5
Ramsay, A.J.6
Shellito, J.E.7
Schurr, J.R.8
Bagby, G.J.9
Nelson, S.10
Kolls, J.K.11
-
14
-
-
29544436136
-
Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosis
-
D. Hartl M. Griese M. Kappler G. Zissel D. Reinhardt C. Rebhan D.J. Schendel S. Krauss-Etschmann Pulmonary T(H)2 response in Pseudomonas aeruginosa -infected patients with cystic fibrosis J. Allergy Clin. Immunol. 117 2006 204 211
-
(2006)
J. Allergy Clin. Immunol.
, vol.117
, pp. 204-211
-
-
Hartl, D.1
Griese, M.2
Kappler, M.3
Zissel, G.4
Reinhardt, D.5
Rebhan, C.6
Schendel, D.J.7
Krauss-Etschmann, S.8
-
15
-
-
21844444831
-
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
-
C.A. Hunter New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions Nat. Rev. Immunol. 5 2005 521 531
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 521-531
-
-
Hunter, C.A.1
-
17
-
-
23244458100
-
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
-
S.A. Khader J.E. Pearl K. Sakamoto L. Gilmartin G.K. Bell D.M. Jelley-Gibbs N. Ghilardi F. deSauvage A.M. Cooper IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available J. Immunol. 175 2005 788 795
-
(2005)
J. Immunol.
, vol.175
, pp. 788-795
-
-
Khader, S.A.1
Pearl, J.E.2
Sakamoto, K.3
Gilmartin, L.4
Bell, G.K.5
Jelley-Gibbs, D.M.6
Ghilardi, N.7
deSauvage, F.8
Cooper, A.M.9
-
19
-
-
0035500298
-
IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis
-
J. Lehmann S. Bellmann C. Werner R. Schroder N. Schutze G. Alber IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis J. Immunol. 167 2001 5304 5315
-
(2001)
J. Immunol.
, vol.167
, pp. 5304-5315
-
-
Lehmann, J.1
Bellmann, S.2
Werner, C.3
Schroder, R.4
Schutze, N.5
Alber, G.6
-
20
-
-
0033847562
-
Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist
-
J.B. Lyczak C.L. Cannon G.B. Pier Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist Microbes Infect. 2 2000 1051 1060
-
(2000)
Microbes Infect.
, vol.2
, pp. 1051-1060
-
-
Lyczak, J.B.1
Cannon, C.L.2
Pier, G.B.3
-
21
-
-
21244455537
-
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
-
F. McAllister A. Henry J.L. Kreindler P.J. Dubin L. Ulrich C. Steele J.D. Finder J.M. Pilewski B.M. Carreno S.J. Goldman J. Pirhonen J.K. Kolls Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis J. Immunol. 175 2005 404 412
-
(2005)
J. Immunol.
, vol.175
, pp. 404-412
-
-
McAllister, F.1
Henry, A.2
Kreindler, J.L.3
Dubin, P.J.4
Ulrich, L.5
Steele, C.6
Finder, J.D.7
Pilewski, J.M.8
Carreno, B.M.9
Goldman, S.J.10
Pirhonen, J.11
Kolls, J.K.12
-
22
-
-
0033937232
-
The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type
-
C. Moser S. Kjaergaard T. Pressler A. Kharazmi C. Koch N. Hoiby The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type Apmis 108 2000 329 335
-
(2000)
Apmis
, vol.108
, pp. 329-335
-
-
Moser, C.1
Kjaergaard, S.2
Pressler, T.3
Kharazmi, A.4
Koch, C.5
Hoiby, N.6
-
23
-
-
5444241502
-
Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression
-
E.D. Murphey C.Y. Lin R.W. McGuire T. Toliver-Kinsky D.N. Herndon E.R. Sherwood Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression Shock 21 2004 415 425
-
(2004)
Shock
, vol.21
, pp. 415-425
-
-
Murphey, E.D.1
Lin, C.Y.2
McGuire, R.W.3
Toliver-Kinsky, T.4
Herndon, D.N.5
Sherwood, E.R.6
-
24
-
-
9244258602
-
Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression
-
E.D. Murphey D.N. Herndon E.R. Sherwood Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression Infect. Immun. 72 2004 6892 6901
-
(2004)
Infect. Immun.
, vol.72
, pp. 6892-6901
-
-
Murphey, E.D.1
Herndon, D.N.2
Sherwood, E.R.3
-
25
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
B. Oppmann R. Lesley B. Blom J.C. Timans Y. Xu B. Hunte F. Vega N. Yu J. Wang K. Singh F. Zonin E. Vaisberg T. Churakova M. Liu D. Gorman J. Wagner S. Zurawski Y. Liu J.S. Abrams K.W. Moore D. Rennick R. de Waal-Malefyt C. Hannum J.F. Bazan R.A. Kastelein Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 2000 715 725
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
Zonin, F.11
Vaisberg, E.12
Churakova, T.13
Liu, M.14
Gorman, D.15
Wagner, J.16
Zurawski, S.17
Liu, Y.18
Abrams, J.S.19
Moore, K.W.20
Rennick, D.21
de Waal-Malefyt, R.22
Hannum, C.23
Bazan, J.F.24
Kastelein, R.A.25
more..
-
26
-
-
10344254339
-
The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice
-
M.R. Power Y. Peng E. Maydanski J.S. Marshall T.J. Lin The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice J. Biol. Chem. 279 2004 49315 49322
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49315-49322
-
-
Power, M.R.1
Peng, Y.2
Maydanski, E.3
Marshall, J.S.4
Lin, T.J.5
-
27
-
-
0030445948
-
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits
-
D.H. Presky H. Yang L.J. Minetti A.O. Chua N. Nabavi C.Y. Wu M.K. Gately U. Gubler A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits Proc. Natl. Acad. Sci. USA 93 1996 14002 14007
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14002-14007
-
-
Presky, D.H.1
Yang, H.2
Minetti, L.J.3
Chua, A.O.4
Nabavi, N.5
Wu, C.Y.6
Gately, M.K.7
Gubler, U.8
-
28
-
-
0032950429
-
Quantitative and qualitative differences in bronchoalveolar inflammatory cells in Pseudomonas aeruginosa-resistant and -susceptible mice
-
K. Sapru P.K. Stotland M.M. Stevenson Quantitative and qualitative differences in bronchoalveolar inflammatory cells in Pseudomonas aeruginosa -resistant and -susceptible mice Clin. Exp. Immunol. 115 1999 103 109
-
(1999)
Clin. Exp. Immunol.
, vol.115
, pp. 103-109
-
-
Sapru, K.1
Stotland, P.K.2
Stevenson, M.M.3
-
30
-
-
0032785433
-
STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis
-
L.M. Stamm A.A. Satoskar S.K. Ghosh J.R. David A.R. Satoskar STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis Eur. J. Immunol. 29 1999 2524 2529
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2524-2529
-
-
Stamm, L.M.1
Satoskar, A.A.2
Ghosh, S.K.3
David, J.R.4
Satoskar, A.R.5
-
31
-
-
0002966198
-
Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17
-
S.V. Subramaniam R.S. Cooper S.E. Adunyah Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17 Biochem. Biophys. Res. Commun. 262 1999 14 19
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 14-19
-
-
Subramaniam, S.V.1
Cooper, R.S.2
Adunyah, S.E.3
-
33
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
G. Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat. Rev. Immunol. 3 2003 133 146
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
34
-
-
27744598776
-
Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice
-
T.K. Varma M. Durham E.D. Murphey W. Cui Z. Huang C.Y. Lin T. Toliver-Kinsky E.R. Sherwood Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice Infect. Immun. 73 2005 7340 7347
-
(2005)
Infect. Immun.
, vol.73
, pp. 7340-7347
-
-
Varma, T.K.1
Durham, M.2
Murphey, E.D.3
Cui, W.4
Huang, Z.5
Lin, C.Y.6
Toliver-Kinsky, T.7
Sherwood, E.R.8
-
35
-
-
0033832306
-
Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature
-
J.G. Wagner R.A. Roth Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature Pharmacol. Rev. 52 2000 349 374
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 349-374
-
-
Wagner, J.G.1
Roth, R.A.2
-
36
-
-
0032960199
-
IL-2 induces STAT4 activation in primary NK cells and NK cell lines, but not in T cells
-
K.S. Wang J. Ritz D.A. Frank IL-2 induces STAT4 activation in primary NK cells and NK cell lines, but not in T cells J. Immunol. 162 1999 299 304
-
(1999)
J. Immunol.
, vol.162
, pp. 299-304
-
-
Wang, K.S.1
Ritz, J.2
Frank, D.A.3
-
38
-
-
0034104818
-
Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis
-
H. Yu S.Z. Nasr V. Deretic Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis Infect. Immun. 68 2000 2142 2147
-
(2000)
Infect. Immun.
, vol.68
, pp. 2142-2147
-
-
Yu, H.1
Nasr, S.Z.2
Deretic, V.3
|