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Volumn 213, Issue 6, 2008, Pages 469-479

Signal transducer and activator of transcription 4 (STAT4), but not IL-12 contributes to Pseudomonas aeruginosa-induced lung inflammation in mice

Author keywords

Cystic fibrosis; Inflammation; Lung; Pseudomonas aeruginosa; STAT4

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; STAT4 PROTEIN; TUMOR NECROSIS FACTOR;

EID: 44349183722     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2007.11.007     Document Type: Article
Times cited : (9)

References (38)
  • 1
    • 0037378951 scopus 로고    scopus 로고
    • Resistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cells
    • I. Aguilar-Delfin P.J. Wettstein D.H. Persing Resistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cells Infect. Immun. 71 2003 2002 2008
    • (2003) Infect. Immun. , vol.71 , pp. 2002-2008
    • Aguilar-Delfin, I.1    Wettstein, P.J.2    Persing, D.H.3
  • 3
    • 0038709564 scopus 로고    scopus 로고
    • Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens
    • A. Bot E. Rodrigo T. Wolfe S. Bot M.G. Von Herrath Infection-triggered regulatory mechanisms override the role of STAT 4 in control of the immune response to influenza virus antigens J. Virol. 77 2003 5794 5800
    • (2003) J. Virol. , vol.77 , pp. 5794-5800
    • Bot, A.1    Rodrigo, E.2    Wolfe, T.3    Bot, S.4    Von Herrath, M.G.5
  • 4
    • 4444279595 scopus 로고    scopus 로고
    • Molecular epidemiology of Pseudomonas aeruginosa, Burkholderia cepacia complex and methicillin-resistant Staphylococcus aureus in a cystic fibrosis center
    • S. Campana G. Taccetti N. Ravenni I. Masi S. Audino B. Sisi T. Repetto G. Doring M. de Martino Molecular epidemiology of Pseudomonas aeruginosa , Burkholderia cepacia complex and methicillin-resistant Staphylococcus aureus in a cystic fibrosis center J. Cyst. Fibros. 3 2004 159 163
    • (2004) J. Cyst. Fibros. , vol.3 , pp. 159-163
    • Campana, S.1    Taccetti, G.2    Ravenni, N.3    Masi, I.4    Audino, S.5    Sisi, B.6    Repetto, T.7    Doring, G.8    de Martino, M.9
  • 5
    • 0030469719 scopus 로고    scopus 로고
    • Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
    • S.S. Cho C.M. Bacon C. Sudarshan R.C. Rees D. Finbloom R. Pine J.J. O’Shea Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation J. Immunol. 157 1996 4781 4789
    • (1996) J. Immunol. , vol.157 , pp. 4781-4789
    • Cho, S.S.1    Bacon, C.M.2    Sudarshan, C.3    Rees, R.C.4    Finbloom, D.5    Pine, R.6    O’Shea, J.J.7
  • 6
    • 0036467445 scopus 로고    scopus 로고
    • Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present
    • A.M. Cooper A. Kipnis J. Turner J. Magram J. Ferrante I.M. Orme Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present J. Immunol. 168 2002 1322 1327
    • (2002) J. Immunol. , vol.168 , pp. 1322-1327
    • Cooper, A.M.1    Kipnis, A.2    Turner, J.3    Magram, J.4    Ferrante, J.5    Orme, I.M.6
  • 10
    • 0033588250 scopus 로고    scopus 로고
    • Urokinase induces activation and formation of Stat4 and Stat1–Stat2 complexes in human vascular smooth muscle cells
    • I. Dumler A. Kopmann K. Wagner O.A. Mayboroda U. Jerke R. Dietz H. Haller D.C. Gulba Urokinase induces activation and formation of Stat4 and Stat1–Stat2 complexes in human vascular smooth muscle cells J. Biol. Chem. 274 1999 24059 24065
    • (1999) J. Biol. Chem. , vol.274 , pp. 24059-24065
    • Dumler, I.1    Kopmann, A.2    Wagner, K.3    Mayboroda, O.A.4    Jerke, U.5    Dietz, R.6    Haller, H.7    Gulba, D.C.8
  • 11
    • 0036127059 scopus 로고    scopus 로고
    • In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70
    • K.L. Elkins A. Cooper S.M. Colombini S.C. Cowley T.L. Kieffer In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70 Infect. Immun. 70 2002 1936 1948
    • (2002) Infect. Immun. , vol.70 , pp. 1936-1948
    • Elkins, K.L.1    Cooper, A.2    Colombini, S.M.3    Cowley, S.C.4    Kieffer, T.L.5
  • 12
    • 0034254823 scopus 로고    scopus 로고
    • Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection
    • M.R. Gyetko S. Sud T. Kendall J.A. Fuller M.W. Newstead T.J. Standiford Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection J. Immunol. 165 2000 1513 1519
    • (2000) J. Immunol. , vol.165 , pp. 1513-1519
    • Gyetko, M.R.1    Sud, S.2    Kendall, T.3    Fuller, J.A.4    Newstead, M.W.5    Standiford, T.J.6
  • 15
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • C.A. Hunter New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions Nat. Rev. Immunol. 5 2005 521 531
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 17
    • 23244458100 scopus 로고    scopus 로고
    • IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
    • S.A. Khader J.E. Pearl K. Sakamoto L. Gilmartin G.K. Bell D.M. Jelley-Gibbs N. Ghilardi F. deSauvage A.M. Cooper IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available J. Immunol. 175 2005 788 795
    • (2005) J. Immunol. , vol.175 , pp. 788-795
    • Khader, S.A.1    Pearl, J.E.2    Sakamoto, K.3    Gilmartin, L.4    Bell, G.K.5    Jelley-Gibbs, D.M.6    Ghilardi, N.7    deSauvage, F.8    Cooper, A.M.9
  • 19
    • 0035500298 scopus 로고    scopus 로고
    • IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis
    • J. Lehmann S. Bellmann C. Werner R. Schroder N. Schutze G. Alber IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis J. Immunol. 167 2001 5304 5315
    • (2001) J. Immunol. , vol.167 , pp. 5304-5315
    • Lehmann, J.1    Bellmann, S.2    Werner, C.3    Schroder, R.4    Schutze, N.5    Alber, G.6
  • 20
    • 0033847562 scopus 로고    scopus 로고
    • Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist
    • J.B. Lyczak C.L. Cannon G.B. Pier Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist Microbes Infect. 2 2000 1051 1060
    • (2000) Microbes Infect. , vol.2 , pp. 1051-1060
    • Lyczak, J.B.1    Cannon, C.L.2    Pier, G.B.3
  • 21
    • 21244455537 scopus 로고    scopus 로고
    • Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
    • F. McAllister A. Henry J.L. Kreindler P.J. Dubin L. Ulrich C. Steele J.D. Finder J.M. Pilewski B.M. Carreno S.J. Goldman J. Pirhonen J.K. Kolls Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis J. Immunol. 175 2005 404 412
    • (2005) J. Immunol. , vol.175 , pp. 404-412
    • McAllister, F.1    Henry, A.2    Kreindler, J.L.3    Dubin, P.J.4    Ulrich, L.5    Steele, C.6    Finder, J.D.7    Pilewski, J.M.8    Carreno, B.M.9    Goldman, S.J.10    Pirhonen, J.11    Kolls, J.K.12
  • 22
    • 0033937232 scopus 로고    scopus 로고
    • The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type
    • C. Moser S. Kjaergaard T. Pressler A. Kharazmi C. Koch N. Hoiby The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type Apmis 108 2000 329 335
    • (2000) Apmis , vol.108 , pp. 329-335
    • Moser, C.1    Kjaergaard, S.2    Pressler, T.3    Kharazmi, A.4    Koch, C.5    Hoiby, N.6
  • 23
    • 5444241502 scopus 로고    scopus 로고
    • Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression
    • E.D. Murphey C.Y. Lin R.W. McGuire T. Toliver-Kinsky D.N. Herndon E.R. Sherwood Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression Shock 21 2004 415 425
    • (2004) Shock , vol.21 , pp. 415-425
    • Murphey, E.D.1    Lin, C.Y.2    McGuire, R.W.3    Toliver-Kinsky, T.4    Herndon, D.N.5    Sherwood, E.R.6
  • 24
    • 9244258602 scopus 로고    scopus 로고
    • Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression
    • E.D. Murphey D.N. Herndon E.R. Sherwood Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression Infect. Immun. 72 2004 6892 6901
    • (2004) Infect. Immun. , vol.72 , pp. 6892-6901
    • Murphey, E.D.1    Herndon, D.N.2    Sherwood, E.R.3
  • 26
    • 10344254339 scopus 로고    scopus 로고
    • The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice
    • M.R. Power Y. Peng E. Maydanski J.S. Marshall T.J. Lin The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice J. Biol. Chem. 279 2004 49315 49322
    • (2004) J. Biol. Chem. , vol.279 , pp. 49315-49322
    • Power, M.R.1    Peng, Y.2    Maydanski, E.3    Marshall, J.S.4    Lin, T.J.5
  • 28
    • 0032950429 scopus 로고    scopus 로고
    • Quantitative and qualitative differences in bronchoalveolar inflammatory cells in Pseudomonas aeruginosa-resistant and -susceptible mice
    • K. Sapru P.K. Stotland M.M. Stevenson Quantitative and qualitative differences in bronchoalveolar inflammatory cells in Pseudomonas aeruginosa -resistant and -susceptible mice Clin. Exp. Immunol. 115 1999 103 109
    • (1999) Clin. Exp. Immunol. , vol.115 , pp. 103-109
    • Sapru, K.1    Stotland, P.K.2    Stevenson, M.M.3
  • 30
    • 0032785433 scopus 로고    scopus 로고
    • STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis
    • L.M. Stamm A.A. Satoskar S.K. Ghosh J.R. David A.R. Satoskar STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis Eur. J. Immunol. 29 1999 2524 2529
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2524-2529
    • Stamm, L.M.1    Satoskar, A.A.2    Ghosh, S.K.3    David, J.R.4    Satoskar, A.R.5
  • 31
    • 0002966198 scopus 로고    scopus 로고
    • Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17
    • S.V. Subramaniam R.S. Cooper S.E. Adunyah Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17 Biochem. Biophys. Res. Commun. 262 1999 14 19
    • (1999) Biochem. Biophys. Res. Commun. , vol.262 , pp. 14-19
    • Subramaniam, S.V.1    Cooper, R.S.2    Adunyah, S.E.3
  • 32
    • 0037241835 scopus 로고    scopus 로고
    • Relative importance of STAT4 in murine tuberculosis
    • I. Sugawara H. Yamada S. Mizuno Relative importance of STAT4 in murine tuberculosis J. Med. Microbiol. 52 2003 29 34
    • (2003) J. Med. Microbiol. , vol.52 , pp. 29-34
    • Sugawara, I.1    Yamada, H.2    Mizuno, S.3
  • 33
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • G. Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat. Rev. Immunol. 3 2003 133 146
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 35
    • 0033832306 scopus 로고    scopus 로고
    • Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature
    • J.G. Wagner R.A. Roth Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature Pharmacol. Rev. 52 2000 349 374
    • (2000) Pharmacol. Rev. , vol.52 , pp. 349-374
    • Wagner, J.G.1    Roth, R.A.2
  • 36
    • 0032960199 scopus 로고    scopus 로고
    • IL-2 induces STAT4 activation in primary NK cells and NK cell lines, but not in T cells
    • K.S. Wang J. Ritz D.A. Frank IL-2 induces STAT4 activation in primary NK cells and NK cell lines, but not in T cells J. Immunol. 162 1999 299 304
    • (1999) J. Immunol. , vol.162 , pp. 299-304
    • Wang, K.S.1    Ritz, J.2    Frank, D.A.3
  • 38
    • 0034104818 scopus 로고    scopus 로고
    • Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis
    • H. Yu S.Z. Nasr V. Deretic Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis Infect. Immun. 68 2000 2142 2147
    • (2000) Infect. Immun. , vol.68 , pp. 2142-2147
    • Yu, H.1    Nasr, S.Z.2    Deretic, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.