-
1
-
-
33747157164
-
The emerging pandemic of obesity and diabetes: Are we doing enough to prevent a disaster?
-
Naser KA, Gruber A, Thomson GA 2006 The emerging pandemic of obesity and diabetes: are we doing enough to prevent a disaster? Int J Clin Pract 60:1093-1097
-
(2006)
Int J Clin Pract
, vol.60
, pp. 1093-1097
-
-
Naser, K.A.1
Gruber, A.2
Thomson, G.A.3
-
2
-
-
33645523067
-
Prevalence of overweight and obesity in the United States, 1999-2004
-
Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM 2006 Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 295:1549-1555
-
(2006)
JAMA
, vol.295
, pp. 1549-1555
-
-
Ogden, C.L.1
Carroll, M.D.2
Curtin, L.R.3
McDowell, M.A.4
Tabak, C.J.5
Flegal, K.M.6
-
4
-
-
0027332738
-
Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates
-
Feinstein R, Kanety H, Papa MZ, Lunenfeld B, Karasik A 1993 Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J Biol Chem 268:26055-26058
-
(1993)
J Biol Chem
, vol.268
, pp. 26055-26058
-
-
Feinstein, R.1
Kanety, H.2
Papa, M.Z.3
Lunenfeld, B.4
Karasik, A.5
-
5
-
-
0029933665
-
Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
-
Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM 1996 Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271:13018-13022
-
(1996)
J Biol Chem
, vol.271
, pp. 13018-13022
-
-
Peraldi, P.1
Hotamisligil, G.S.2
Buurman, W.A.3
White, M.F.4
Spiegelman, B.M.5
-
6
-
-
0030206997
-
Inhibition of insulin receptor signaling by TNF: Potential role in obesity and non-insulin-dependent diabetes mellitus
-
Skolnik EY, Marcusohn J 1996 Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus. Cytokine Growth Factor Rev 7:161-173
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 161-173
-
-
Skolnik, E.Y.1
Marcusohn, J.2
-
7
-
-
0038039463
-
Tumour necrosis factor α: A key regulator of adipose tissue mass
-
Warne JP 2003 Tumour necrosis factor α: a key regulator of adipose tissue mass. J Endocrinol 177:351-355
-
(2003)
J Endocrinol
, vol.177
, pp. 351-355
-
-
Warne, J.P.1
-
8
-
-
0041374029
-
Insulin resistance in adipose tissue: Direct and indirect effects of tumor necrosis factor-α
-
Ruan H, Lodish HF 2003 Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-α. Cytokine Growth Factor Rev 14:447-455
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 447-455
-
-
Ruan, H.1
Lodish, H.F.2
-
9
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM 1993 Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 259:87-91
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
10
-
-
0027972524
-
Altered gene expression for tumor necrosis factor-α and its receptors during drug and dietary modulation of insulin resistance
-
Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS, Spiegelman BM 1994 Altered gene expression for tumor necrosis factor-α and its receptors during drug and dietary modulation of insulin resistance. Endocrinology 134:264-270
-
(1994)
Endocrinology
, vol.134
, pp. 264-270
-
-
Hofmann, C.1
Lorenz, K.2
Braithwaite, S.S.3
Colca, J.R.4
Palazuk, B.J.5
Hotamisligil, G.S.6
Spiegelman, B.M.7
-
11
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM 1995 Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 95:2409-2415
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
12
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB 1995 The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119
-
(1995)
J Clin Invest
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizadeh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
13
-
-
0031784544
-
Tumor necrosis factor-α in sera of obese patients: Fall with weight loss
-
Dandona P, Weinstock R, Thusu K, Abdel-Rahman E, Aljada A, Wadden T 1998 Tumor necrosis factor-α in sera of obese patients: fall with weight loss. J Clin Endocrinol Metab 83:2907-2910
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2907-2910
-
-
Dandona, P.1
Weinstock, R.2
Thusu, K.3
Abdel-Rahman, E.4
Aljada, A.5
Wadden, T.6
-
14
-
-
0026549669
-
Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output
-
Lang CH, Dobrescu C, Bagby GJ 1992 Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 130:43-52
-
(1992)
Endocrinology
, vol.130
, pp. 43-52
-
-
Lang, C.H.1
Dobrescu, C.2
Bagby, G.J.3
-
16
-
-
0030661983
-
TNF-α-induced insulin resistance in vivo and its prevention by troglitazone
-
Miles PD, Romeo OM, Higo K, Cohen A, Rafaat K, Olefsky JM 1997 TNF-α-induced insulin resistance in vivo and its prevention by troglitazone. Diabetes 46:1678-1683
-
(1997)
Diabetes
, vol.46
, pp. 1678-1683
-
-
Miles, P.D.1
Romeo, O.M.2
Higo, K.3
Cohen, A.4
Rafaat, K.5
Olefsky, J.M.6
-
17
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS 1997 Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389:610-614
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
19
-
-
0031757099
-
Functional analysis of tumor necrosis factor (TNF) receptors in TNF-α-mediated insulin resistance in genetic obesity
-
Uysal KT, Wiesbrock SM, Hotamisligil GS 1998 Functional analysis of tumor necrosis factor (TNF) receptors in TNF-α-mediated insulin resistance in genetic obesity. Endocrinology 139:4832-4838
-
(1998)
Endocrinology
, vol.139
, pp. 4832-4838
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Hotamisligil, G.S.3
-
20
-
-
0032587240
-
The role of TNFα and TNF receptors in obesity and insulin resistance
-
Hotamisligil GS 1999 The role of TNFα and TNF receptors in obesity and insulin resistance. J Intern Med 245:621-625
-
(1999)
J Intern Med
, vol.245
, pp. 621-625
-
-
Hotamisligil, G.S.1
-
21
-
-
0034455628
-
The two tumor necrosis factor receptors mediate opposite effects on differentiation and glucose metabolism in human adipocytes in primary culture
-
Hube F, Hauner H 2000 The two tumor necrosis factor receptors mediate opposite effects on differentiation and glucose metabolism in human adipocytes in primary culture. Endocrinology 141:2582-2588
-
(2000)
Endocrinology
, vol.141
, pp. 2582-2588
-
-
Hube, F.1
Hauner, H.2
-
22
-
-
0034598978
-
Characterisation of receptor-specific TNFα functions in adipocyte cell lines lacking type 1 and 2 TNF receptors
-
Sethi JK, Xu H, Uysal KT, Wiesbrock SM, Scheja L, Hotamisligil GS 2000 Characterisation of receptor-specific TNFα functions in adipocyte cell lines lacking type 1 and 2 TNF receptors. FEBS Lett 469:77-82
-
(2000)
FEBS Lett
, vol.469
, pp. 77-82
-
-
Sethi, J.K.1
Xu, H.2
Uysal, K.T.3
Wiesbrock, S.M.4
Scheja, L.5
Hotamisligil, G.S.6
-
23
-
-
0042814856
-
Screening for TNF-α related peptides by phage display system]
-
Chinese
-
Yei F, Jiang X, Li Z, Gong F, Xu Y, Feng W, Ping X 2002 [Screening for TNF-α related peptides by phage display system]. Chin J Microbiol Immunol 22:366-371 (Chinese)
-
(2002)
Chin J Microbiol Immunol
, vol.22
, pp. 366-371
-
-
Yei, F.1
Jiang, X.2
Li, Z.3
Gong, F.4
Xu, Y.5
Feng, W.6
Ping, X.7
-
24
-
-
1542675296
-
The rat model of type 2 diabetic mellitus and its glycometabolism characters
-
Zhang F, Ye C, Li G, Ding W, Zhou W, Zhu H, Chen G, Luo T, Guang M, Liu Y, Zhang D, Zheng S, Yang J, Gu Y, Xie X, Luo M 2003 The rat model of type 2 diabetic mellitus and its glycometabolism characters. Exp Anim 52:401-407
-
(2003)
Exp Anim
, vol.52
, pp. 401-407
-
-
Zhang, F.1
Ye, C.2
Li, G.3
Ding, W.4
Zhou, W.5
Zhu, H.6
Chen, G.7
Luo, T.8
Guang, M.9
Liu, Y.10
Zhang, D.11
Zheng, S.12
Yang, J.13
Gu, Y.14
Xie, X.15
Luo, M.16
-
25
-
-
44249087987
-
Preparation, purification and identification of the rabbit antibody against extracellular region of mLAIR-1]
-
Chinese
-
Zhang Y, Zhuang R, Jin BQ, Ouyang WM 2005 [Preparation, purification and identification of the rabbit antibody against extracellular region of mLAIR-1]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 21:595-597 (Chinese)
-
(2005)
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
, vol.21
, pp. 595-597
-
-
Zhang, Y.1
Zhuang, R.2
Jin, B.Q.3
Ouyang, W.M.4
-
26
-
-
0036703489
-
Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin
-
Rigato F, Garwood J, Calco V, Heck N, Faivre-Sarrailh C, Faissner A 2002 Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin. J Neurosci 22:6596-6609
-
(2002)
J Neurosci
, vol.22
, pp. 6596-6609
-
-
Rigato, F.1
Garwood, J.2
Calco, V.3
Heck, N.4
Faivre-Sarrailh, C.5
Faissner, A.6
-
27
-
-
0032198642
-
CNI-1493 attenuates hemodynamic and pro-inflammatory responses to LPS
-
Molina PE, Qian L, Schuhlein D, Naukam R, Wang H, Tracey KJ, Abumrad NN 1998 CNI-1493 attenuates hemodynamic and pro-inflammatory responses to LPS. Shock 10:329-334
-
(1998)
Shock
, vol.10
, pp. 329-334
-
-
Molina, P.E.1
Qian, L.2
Schuhlein, D.3
Naukam, R.4
Wang, H.5
Tracey, K.J.6
Abumrad, N.N.7
-
28
-
-
18344382724
-
Targeted deletion of the PRL receptor: Effects on islet development, insulin production, and glucose tolerance
-
Freemark M, Avril I, Fleenor D, Driscoll P, Petro A, Opara E, Kendall W, Oden J, Bridges S, Binart N, Breant B, Kelly PA 2002 Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. Endocrinology 143:1378-1385
-
(2002)
Endocrinology
, vol.143
, pp. 1378-1385
-
-
Freemark, M.1
Avril, I.2
Fleenor, D.3
Driscoll, P.4
Petro, A.5
Opara, E.6
Kendall, W.7
Oden, J.8
Bridges, S.9
Binart, N.10
Breant, B.11
Kelly, P.A.12
-
29
-
-
0034749551
-
Impaired insulin-receptor autophosphorylation is an early defect in fat-fed, insulin-resistant rats
-
Youngren JF, Paik J, Barnard RJ 2001 Impaired insulin-receptor autophosphorylation is an early defect in fat-fed, insulin-resistant rats. J Appl Physiol 91:2240-2247
-
(2001)
J Appl Physiol
, vol.91
, pp. 2240-2247
-
-
Youngren, J.F.1
Paik, J.2
Barnard, R.J.3
-
30
-
-
33846577803
-
The effect of TNF receptor blocking peptide on the functions of rat peritoneal macrophages
-
Chinese
-
He Y, Yin B, Zhuoya L 2003 [The effect of TNF receptor blocking peptide on the functions of rat peritoneal macrophages.] Zhong Guo Mian Yi Xue Za Zhi 19:385-389 (Chinese)
-
(2003)
Zhong Guo Mian Yi Xue Za Zhi
, vol.19
, pp. 385-389
-
-
He, Y.1
Yin, B.2
Zhuoya, L.3
-
31
-
-
4444312860
-
Effects of TNF-α receptor blocking peptide on adjuvant arthritis in rats.]
-
Chinese
-
He YP, Li ZY, Jiang XD, Feng W, Xu Y, Xiong P 2003 [Effects of TNF-α receptor blocking peptide on adjuvant arthritis in rats.] Yao Xue Xue Bao 38:889-892 (Chinese)
-
(2003)
Yao Xue Xue Bao
, vol.38
, pp. 889-892
-
-
He, Y.P.1
Li, Z.Y.2
Jiang, X.D.3
Feng, W.4
Xu, Y.5
Xiong, P.6
-
32
-
-
0029906375
-
Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
-
Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R 1996 Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45:881-885
-
(1996)
Diabetes
, vol.45
, pp. 881-885
-
-
Ofei, F.1
Hurel, S.2
Newkirk, J.3
Sopwith, M.4
Taylor, R.5
-
33
-
-
0034454915
-
No increased insulin sensitivity after a single intravenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients
-
Paquot N, Castillo MJ, Lefebvre PJ, Scheen AJ 2000 No increased insulin sensitivity after a single intravenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients. J Clin Endocrinol Metab 85:1316-1319
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 1316-1319
-
-
Paquot, N.1
Castillo, M.J.2
Lefebvre, P.J.3
Scheen, A.J.4
-
34
-
-
0023638415
-
Tumors secreting human TNF/cachectin induce cachexia in mice
-
Oliff A, Defeo-Jones D, Boyer M, Martinez D, Kiefer D, Vuocolo G, Wolfe A, Socher SH 1987 Tumors secreting human TNF/cachectin induce cachexia in mice. Cell 50:555-563
-
(1987)
Cell
, vol.50
, pp. 555-563
-
-
Oliff, A.1
Defeo-Jones, D.2
Boyer, M.3
Martinez, D.4
Kiefer, D.5
Vuocolo, G.6
Wolfe, A.7
Socher, S.H.8
-
35
-
-
1942424955
-
Targets for TNF-α-induced lipolysis in human adipocytes
-
Ryden M, Arvidsson E, Blomqvist L, Perbeck L, Dicker A, Arner P 2004 Targets for TNF-α-induced lipolysis in human adipocytes. Biochem Biophys Res Commun 318:168-175
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 168-175
-
-
Ryden, M.1
Arvidsson, E.2
Blomqvist, L.3
Perbeck, L.4
Dicker, A.5
Arner, P.6
-
36
-
-
0024968332
-
Tumor necrosis factor α (cachectin). Biological properties and role in physiopathology
-
Blay JY, Chouaib S 1989 Tumor necrosis factor α (cachectin). Biological properties and role in physiopathology. Presse Med 18:975-979
-
(1989)
Presse Med
, vol.18
, pp. 975-979
-
-
Blay, J.Y.1
Chouaib, S.2
-
37
-
-
0028587742
-
Tumor necrosis factor α: A key component of the obesity-diabetes link
-
Hotamisligil GS, Spiegelman BM 1994 Tumor necrosis factor α: a key component of the obesity-diabetes link. Diabetes 43:1271-1278
-
(1994)
Diabetes
, vol.43
, pp. 1271-1278
-
-
Hotamisligil, G.S.1
Spiegelman, B.M.2
-
38
-
-
0024378046
-
Persistence of the hypertriglyceridemic effect of tumor necrosis factor despite development of tachyphylaxis to its anorectic/cachectic effects in rats
-
Grunfeld C, Wilking H, Neese R, Gavin LA, Moser AH, Gulli R, Serio MK, Feingold KR 1989 Persistence of the hypertriglyceridemic effect of tumor necrosis factor despite development of tachyphylaxis to its anorectic/cachectic effects in rats. Cancer Res 49:2554-2560
-
(1989)
Cancer Res
, vol.49
, pp. 2554-2560
-
-
Grunfeld, C.1
Wilking, H.2
Neese, R.3
Gavin, L.A.4
Moser, A.H.5
Gulli, R.6
Serio, M.K.7
Feingold, K.R.8
-
39
-
-
0030864185
-
Targeted disruption of the tumor necrosis factor-α gene: Metabolic consequences in obese and nonobese mice
-
Ventre J, Doebber T, Wu M, MacNaul K, Stevens K, Pasparakis M, Kollias G, Moller DE 1997 Targeted disruption of the tumor necrosis factor-α gene: metabolic consequences in obese and nonobese mice. Diabetes 46:1526-1531
-
(1997)
Diabetes
, vol.46
, pp. 1526-1531
-
-
Ventre, J.1
Doebber, T.2
Wu, M.3
MacNaul, K.4
Stevens, K.5
Pasparakis, M.6
Kollias, G.7
Moller, D.E.8
-
40
-
-
0031577286
-
KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-α production
-
Morimoto Y, Nishikawa K, Ohashi M 1997 KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-α production. Life Sci 61:795-803
-
(1997)
Life Sci
, vol.61
, pp. 795-803
-
-
Morimoto, Y.1
Nishikawa, K.2
Ohashi, M.3
-
41
-
-
0034852786
-
Free fatty acids-the link between obesity and insulin resistance
-
Boden G 2001 Free fatty acids-the link between obesity and insulin resistance. Endocr Pract 7:44-51
-
(2001)
Endocr Pract
, vol.7
, pp. 44-51
-
-
Boden, G.1
-
42
-
-
0036134187
-
Resistin and obesity-associated insulin resistance
-
Steppan CM, Lazar MA 2002 Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 13:18-23
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 18-23
-
-
Steppan, C.M.1
Lazar, M.A.2
-
43
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
Kadowaki T, Yamauchi T 2005 Adiponectin and adiponectin receptors. Endocr Rev 26:439-451
-
(2005)
Endocr Rev
, vol.26
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
44
-
-
0028031569
-
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-α
-
Hotamisligil GS, Budavari A, Murray D, Spiegelman BM 1994 Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-α. J Clin Invest 94:1543-1549
-
(1994)
J Clin Invest
, vol.94
, pp. 1543-1549
-
-
Hotamisligil, G.S.1
Budavari, A.2
Murray, D.3
Spiegelman, B.M.4
-
45
-
-
0031756640
-
An in vivo model for elucidation of the mechanism of tumor necrosis factor-α (TNF-α)-induced insulin resistance: Evidence for differential regulation of insulin signaling by TNF-α
-
Cheung AT, Ree D, Kolls JK, Fuselier J, Coy DH, Bryer-Ash M 1998 An in vivo model for elucidation of the mechanism of tumor necrosis factor-α (TNF-α)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-α. Endocrinology 139:4928-4935
-
(1998)
Endocrinology
, vol.139
, pp. 4928-4935
-
-
Cheung, A.T.1
Ree, D.2
Kolls, J.K.3
Fuselier, J.4
Coy, D.H.5
Bryer-Ash, M.6
|