-
1
-
-
20444418706
-
MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression
-
10.1016/j.cbpa.2005.04.004 15939336
-
Johnson GL Dohlman HG Graves LM MAPK kinase kinases (MKKKs) as a target class for small-molecule inhibition to modulate signaling networks and gene expression Current Opinion in Chemical Biology 2005 9:325-331 10.1016/j.cbpa.2005.04.004 15939336
-
(2005)
Current Opinion in Chemical Biology
, vol.9
, pp. 325-331
-
-
Johnson, G.L.1
Dohlman, H.G.2
Graves, L.M.3
-
3
-
-
34447329284
-
Distinct functions for ERKs?
-
1781519 16879721 10.1186/jbiol46
-
Lloyd A Distinct functions for ERKs? Journal of Biology 2006 5:13 1781519 16879721 10.1186/jbiol46
-
(2006)
Journal of Biology
, vol.5
, pp. 13
-
-
Lloyd, A.1
-
4
-
-
34047129136
-
Mek1/2 MAPK Kinases Are Essential for Mammalian Development, Homeostasis, and Raf-Induced Hyperplasia
-
10.1016/j.devcel.2007.03.009 17419998
-
Scholl FA Dumesic PA Barragan DI Harada K Bissonauth V Charron J Khavari PA Mek1/2 MAPK Kinases Are Essential for Mammalian Development, Homeostasis, and Raf-Induced Hyperplasia Developmental Cell 2007 12:615-629 10.1016/j.devcel.2007.03.009 17419998
-
(2007)
Developmental Cell
, vol.12
, pp. 615-629
-
-
Scholl, F.A.1
Dumesic, P.A.2
Barragan, D.I.3
Harada, K.4
Bissonauth, V.5
Charron, J.6
Khavari, P.A.7
-
5
-
-
17144458301
-
Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout Mice
-
10.1126/science.286.5443.1374 10558995
-
Pagès G Guérin S Grall D Bonino F Smith A Anjuere F Auberger P Pouysségur J Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout Mice Science 1999 286:1374-1377 10.1126/ science.286.5443.1374 10558995
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pagès, G.1
Guérin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
Auberger, P.7
Pouysségur, J.8
-
6
-
-
0242607637
-
An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development4
-
1326397 14502223 10.1038/sj.embor.embor939
-
Saba-El-Leil MK Vella FDJ Vernay B Voisin L Chen L Labrecque N Ang SL Meloche S An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development4 Embo Reports 2003 4:964-968 1326397 14502223 10.1038/sj.embor.embor939
-
(2003)
Embo Reports
, vol.4
, pp. 964-968
-
-
Saba-El-Leil, M.K.1
Vella, F.D.J.2
Vernay, B.3
Voisin, L.4
Chen, L.5
Labrecque, N.6
Ang, S.L.7
Meloche, S.8
-
7
-
-
0030575542
-
Signals for mesoderm induction. Roles of fibroblast growth factor (FGF)/ mitogen-activated protein kinase (MAPK) pathway
-
10.1016/0304-419X(96)00009-1 8764836
-
Gotoh Y Nishida E Signals for mesoderm induction. Roles of fibroblast growth factor (FGF)/mitogen-activated protein kinase (MAPK) pathway Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1996 1288:F1-F7 10.1016/0304-419X(96)00009-1 8764836
-
(1996)
Biochimica Et Biophysica Acta (BBA) - Reviews on Cancer
, vol.1288
-
-
Gotoh, Y.1
Nishida, E.2
-
8
-
-
13444263240
-
Fibroblast Growth Factor Signaling during Early Vertebrate Development
-
10.1210/er.2003-0040 15689573
-
Bottcher RT Niehrs C Fibroblast Growth Factor Signaling during Early Vertebrate Development Endocr Rev 2005 26:63-77 10.1210/er.2003-0040 15689573
-
(2005)
Endocr Rev
, vol.26
, pp. 63-77
-
-
Bottcher, R.T.1
Niehrs, C.2
-
9
-
-
0033780376
-
Effective targeted gene /'knockdown/' in zebrafish
-
10.1038/79951 11017081
-
Nasevicius A Ekker SC Effective targeted gene /'knockdown/' in zebrafish Nat Genet 2000 26:216-220 10.1038/79951 11017081
-
(2000)
Nat Genet
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
10
-
-
0036578644
-
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways1
-
10.1038/ng0502-19 11984561
-
Dahlquist KD Salomonis N Vranizan K Lawlor SC Conklin BR GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways1 Nature Genetics 2002 31:19-20 10.1038/ng0502-19 11984561
-
(2002)
Nature Genetics
, vol.31
, pp. 19-20
-
-
Dahlquist, K.D.1
Salomonis, N.2
Vranizan, K.3
Lawlor, S.C.4
Conklin, B.R.5
-
11
-
-
44249084570
-
-
GenMAPP 2008 http://www.genmapp.org/
-
(2008)
GenMAPP
-
-
-
12
-
-
28944448921
-
Molecular genetics of axis formation in zebrafish
-
10.1146/annurev.genet.37.110801.143752
-
Schier A.F. TWS Molecular genetics of axis formation in zebrafish Annu Rev Genet 2005 39 561 613 http://arjournals.annualreviews.org/doi/abs/ 10.1146/annurev.genet.37.110801.143752 10.1146/ annurev.genet.37.110801.143752 16285872
-
(2005)
Annu Rev Genet
, vol.39
, pp. 561-613
-
-
Schier, A.F.T.W.S.1
-
15
-
-
0034663223
-
Patterning the Early Zebrafish by the Opposing Actions of bozozok and vox/vent
-
10.1006/dbio.2000.9780 10926766
-
Melby AE Beach C Mullins M Kimelman D Patterning the Early Zebrafish by the Opposing Actions of bozozok and vox/vent Developmental Biology 2000 224:275-285 10.1006/dbio.2000.9780 10926766
-
(2000)
Developmental Biology
, vol.224
, pp. 275-285
-
-
Melby, A.E.1
Beach, C.2
Mullins, M.3
Kimelman, D.4
-
16
-
-
4544357312
-
Developmentally Restricted Actin-Regulatory Molecules Control Morphogenetic Cell Movements in the Zebrafish Gastrula
-
10.1016/j.cub.2004.08.024 15380064
-
Daggett DF Boyd CA Gautier P Bryson-Richardson RJ Thisse C Thisse B Amacher SL Currie PD Developmentally Restricted Actin-Regulatory Molecules Control Morphogenetic Cell Movements in the Zebrafish Gastrula Current Biology 2004 14:1632-1638 10.1016/j.cub.2004.08.024 15380064
-
(2004)
Current Biology
, vol.14
, pp. 1632-1638
-
-
Daggett, D.F.1
Boyd, C.A.2
Gautier, P.3
Bryson-Richardson, R.J.4
Thisse, C.5
Thisse, B.6
Amacher, S.L.7
Currie, P.D.8
-
17
-
-
0042887599
-
One-eyed pinhead regulates cell motility independent of Squint/Cyclops signaling
-
10.1016/S0012-1606(03)00328-2 14499649
-
Warga RM Kane DA One-eyed pinhead regulates cell motility independent of Squint/Cyclops signaling Developmental Biology 2003 261:391-411 10.1016/ S0012-1606(03)00328-2 14499649
-
(2003)
Developmental Biology
, vol.261
, pp. 391-411
-
-
Warga, R.M.1
Kane, D.A.2
-
18
-
-
33748800240
-
FGF signaling is required for {beta}-catenin-mediated induction of the zebrafish organizer
-
10.1242/dev.02483 16873584
-
Maegawa S Varga M Weinberg ES FGF signaling is required for {beta}-catenin-mediated induction of the zebrafish organizer Development 2006 133:3265-3276 10.1242/dev.02483 16873584
-
(2006)
Development
, vol.133
, pp. 3265-3276
-
-
Maegawa, S.1
Varga, M.2
Weinberg, E.S.3
-
19
-
-
0032562603
-
Functional Interaction of an Axin Homolog, Conductin, with {beta}-Catenin, APC, and GSK3
-
hl M 10.1126/science.280.5363.596 9554852
-
Behrens J Jerchow BA Rtele M Grimm J Asbrand C Wirtz R hl M Wedlich D Birchmeier W Functional Interaction of an Axin Homolog, Conductin, with {beta}-Catenin, APC, and GSK3 Science 1998 280:596-599 10.1126/ science.280.5363.596 9554852
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Rtele, M.3
Grimm, J.4
Asbrand, C.5
Wirtz, R.6
Wedlich, D.7
Birchmeier, W.8
-
20
-
-
0027278279
-
Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish
-
8104775
-
Stachel SE Grunwald DJ Myers PZ Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish Development 1993 117:1261-1274 8104775
-
(1993)
Development
, vol.117
, pp. 1261-1274
-
-
Stachel, S.E.1
Grunwald, D.J.2
Myers, P.Z.3
-
21
-
-
0032943366
-
Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction
-
9847237
-
Thisse C Thisse B Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction Development 1999 126:229-240 9847237
-
(1999)
Development
, vol.126
, pp. 229-240
-
-
Thisse, C.1
Thisse, B.2
-
22
-
-
0027077930
-
The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo
-
1295726
-
Schulte-Merker S Ho RK Herrmann BG Nusslein-Volhard C The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo Development 1992 116:1021-1032 1295726
-
(1992)
Development
, vol.116
, pp. 1021-1032
-
-
Schulte-Merker, S.1
Ho, R.K.2
Herrmann, B.G.3
Nusslein-Volhard, C.4
-
23
-
-
0142074396
-
Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development
-
10.1242/dev.00671
-
Draper BW Stock DW Kimmel CB Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development Development 2003 130 4639 4654 10.1242/dev.00671 12925590
-
(2003)
Development
, vol.130
, pp. 4639-4654
-
-
Draper, B.W.1
Stock, D.W.2
Kimmel, C.B.3
-
24
-
-
0344494808
-
Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development
-
10.1016/j.ydbio.2003.09.008 14651930
-
Griffin KJP Kimelman D Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development Developmental Biology 2003 264:456-466 10.1016/j.ydbio.2003.09.008 14651930
-
(2003)
Developmental Biology
, vol.264
, pp. 456-466
-
-
Griffin, K.J.P.1
Kimelman, D.2
-
25
-
-
0031106250
-
tbx6,aBrachyury-Related Gene Expressed by Ventral Mesendodermal Precursors in the Zebrafish Embryo
-
10.1006/dbio.1996.8490 9119115
-
Hug B Walter V Grunwald DJ tbx6,aBrachyury-Related Gene Expressed by Ventral Mesendodermal Precursors in the Zebrafish Embryo Developmental Biology 1997 183:61-73 10.1006/dbio.1996.8490 9119115
-
(1997)
Developmental Biology
, vol.183
, pp. 61-73
-
-
Hug, B.1
Walter, V.2
Grunwald, D.J.3
-
26
-
-
0242300107
-
Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation
-
240691 14566055 10.1073/pnas.2134254100
-
Yao Y Li W Wu J Germann UA Su MSS Kuida K Boucher DM Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation PNAS 2003 100:12759-12764 240691 14566055 10.1073/pnas.2134254100
-
(2003)
PNAS
, vol.100
, pp. 12759-12764
-
-
Yao, Y.1
Li, W.2
Wu, J.3
Germann, U.A.4
Su, M.S.S.5
Kuida, K.6
Boucher, D.M.7
-
27
-
-
1242290740
-
Mek2 Is Dispensable for Mouse Growth and Development
-
162209 10.1128/MCB.23.14.4778-4787.2003
-
Belanger LF Roy S Tremblay M Brott B Steff AM Mourad W Hugo P Erikson R Charron J Mek2 Is Dispensable for Mouse Growth and Development Mol Cell Biol 2003 23:4778-4787 162209 12832465 10.1128/MCB.23.14.4778-4787.2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4778-4787
-
-
Belanger, L.F.1
Roy, S.2
Tremblay, M.3
Brott, B.4
Steff, A.M.5
Mourad, W.6
Hugo, P.7
Erikson, R.8
Charron, J.9
-
28
-
-
33749389685
-
Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis
-
10.1242/dev.02526 16887817
-
Bissonauth V Roy S Gravel M Guillemette S Charron J Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis Development 2006 133:3429-3440 10.1242/dev.02526 16887817
-
(2006)
Development
, vol.133
, pp. 3429-3440
-
-
Bissonauth, V.1
Roy, S.2
Gravel, M.3
Guillemette, S.4
Charron, J.5
-
29
-
-
34247618721
-
Concise Review: Regulation of Embryonic Stem Cell Lineage Commitment by Mitogen-Activated Protein Kinases
-
10.1634/stemcells.2006-0612 17218395
-
Binetruy B Heasley L Bost F Caron L Aouadi M Concise Review: Regulation of Embryonic Stem Cell Lineage Commitment by Mitogen-Activated Protein Kinases Stem Cells 2007 25:1090-1095 10.1634/stemcells.2006-0612 17218395
-
(2007)
Stem Cells
, vol.25
, pp. 1090-1095
-
-
Binetruy, B.1
Heasley, L.2
Bost, F.3
Caron, L.4
Aouadi, M.5
-
30
-
-
14544298335
-
The role of MAPKs in adipocyte differentiation and obesity
-
10.1016/j.biochi.2004.10.018 15733737
-
Bost F Aouadi M Caron L Binetruy B The role of MAPKs in adipocyte differentiation and obesity Biochimie 2005 87:51-56 10.1016/ j.biochi.2004.10.018 15733737
-
(2005)
Biochimie
, vol.87
, pp. 51-56
-
-
Bost, F.1
Aouadi, M.2
Caron, L.3
Binetruy, B.4
-
31
-
-
0038776380
-
Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARgamma
-
10.1126/science.274.5295.2100 8953045
-
Hu E Kim JB Sarraf P Bruce M Spiegelman Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARgamma Science 1996 274:2100-2103 10.1126/science.274.5295.2100 8953045
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Bruce, M.4
Spiegelman5
-
32
-
-
0030964085
-
Regulation of Peroxisome Proliferator-activated Receptor gamma Activity by Mitogen-activated Protein Kinase
-
10.1074/jbc.272.16.10811 9099735
-
Camp HS Tafuri SR Regulation of Peroxisome Proliferator-activated Receptor gamma Activity by Mitogen-activated Protein Kinase Journal of Biological Chemistry 1997 272:10811-10816 10.1074/jbc.272.16.10811 9099735
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 10811-10816
-
-
Camp, H.S.1
Tafuri, S.R.2
-
33
-
-
33646172661
-
Mesoderm induction: From caps to chips1
-
10.1038/nrg1837 16619051
-
Kimelman D Mesoderm induction: From caps to chips1 Nature Reviews Genetics 2006 7:360-372 10.1038/nrg1837 16619051
-
(2006)
Nature Reviews Genetics
, vol.7
, pp. 360-372
-
-
Kimelman, D.1
-
34
-
-
0041530319
-
The molecular nature of the zebrafish tail organizer
-
10.1038/nature01822 12879074
-
Agathon A Thisse C Thisse B The molecular nature of the zebrafish tail organizer Nature 2003 424:448-452 10.1038/nature01822 12879074
-
(2003)
Nature
, vol.424
, pp. 448-452
-
-
Agathon, A.1
Thisse, C.2
Thisse, B.3
-
35
-
-
12644274664
-
Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio2
-
9007236
-
Hammerschmidt M Pelegri F Mullins MC Kane DA Brand M vanEeden FJM FurutaniSeiki M Granato M Haffter P Heisenberg CP Jiang YJ Kelsh RN Odenthal J Warga RM NussleinVolhard C Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio2 Development 1996 123:143-151 9007236
-
(1996)
Development
, vol.123
, pp. 143-151
-
-
Hammerschmidt, M.1
Pelegri, F.2
Mullins, M.C.3
Kane, D.A.4
Brand, M.5
vanEeden, F.J.M.6
FurutaniSeiki, M.7
Granato, M.8
Haffter, P.9
Heisenberg, C.P.10
Jiang, Y.J.11
Kelsh, R.N.12
Odenthal, J.13
Warga, R.M.14
NussleinVolhard, C.15
-
36
-
-
1242307432
-
Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
-
10.1242/dev.00964 14711879
-
Mathieu J Griffin K Herbomel P Dickmeis T Strahle U Kimelman D Rosa FM Peyrieras N Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations Development 2004 131:629-641 10.1242/dev.00964 14711879
-
(2004)
Development
, vol.131
, pp. 629-641
-
-
Mathieu, J.1
Griffin, K.2
Herbomel, P.3
Dickmeis, T.4
Strahle, U.5
Kimelman, D.6
Rosa, F.M.7
Peyrieras, N.8
-
37
-
-
33845453906
-
Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish1
-
10.1016/j.ydbio.2006.08.073 17026981
-
Mizoguchi T Izawa T Kuroiwa A Kikuchi Y Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish1 Developmental Biology 2006 300:612-622 10.1016/j.ydbio.2006.08.073 17026981
-
(2006)
Developmental Biology
, vol.300
, pp. 612-622
-
-
Mizoguchi, T.1
Izawa, T.2
Kuroiwa, A.3
Kikuchi, Y.4
-
38
-
-
0030785482
-
MAP kinase in situ activation atlas during Drosophila embryogenesis
-
9342046
-
Gabay L Seger R Shilo BZ MAP kinase in situ activation atlas during Drosophila embryogenesis Development 1997 124:3535-3541 9342046
-
(1997)
Development
, vol.124
, pp. 3535-3541
-
-
Gabay, L.1
Seger, R.2
Shilo, B.Z.3
-
39
-
-
1942445034
-
FGF8-like1 and FGF8-like2 encode putative ligands of the FGF receptor Htl for mesoderm migration and are required in the Drosophila gastrula2
-
10.1016/j.cub.2004.03.058 15084280
-
Gryzik T Muller HAJ FGF8-like1 and FGF8-like2 encode putative ligands of the FGF receptor Htl for mesoderm migration and are required in the Drosophila gastrula2 Current Biology 2004 14:659-667 10.1016/ j.cub.2004.03.058 15084280
-
(2004)
Current Biology
, vol.14
, pp. 659-667
-
-
Gryzik, T.1
Muller, H.A.J.2
-
40
-
-
1842842204
-
Pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos
-
10.1101/gad.1166404 387243
-
Stathopoulos A Tam B Ronshaugen M Frasch M Levine M pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos Genes and Development 2004 18:687-699 10.1101/gad.1166404 15075295 387243
-
(2004)
Genes and Development
, vol.18
, pp. 687-699
-
-
Stathopoulos, A.1
Tam, B.2
Ronshaugen, M.3
Frasch, M.4
Levine, M.5
-
41
-
-
0029002456
-
Involvement of the Map Kinase Cascade in Xenopus Mesoderm Induction1
-
398362 7781601
-
Gotoh Y Masuyama N Suzuki A Ueno N Nishida E Involvement of the Map Kinase Cascade in Xenopus Mesoderm Induction1 Embo Journal 1995 14:2491-2498 398362 7781601
-
(1995)
Embo Journal
, vol.14
, pp. 2491-2498
-
-
Gotoh, Y.1
Masuyama, N.2
Suzuki, A.3
Ueno, N.4
Nishida, E.5
-
42
-
-
0036333268
-
Molecular integration of casanova in the Nodal signalling pathway controlling endoderm formation
-
11807021
-
Aoki TO David NB Minchiotti G Saint-Etienne L Dickmeis T Persico GM Strahle U Mourrain P Rosa FM Molecular integration of casanova in the Nodal signalling pathway controlling endoderm formation Development 2002 129:275-286 11807021
-
(2002)
Development
, vol.129
, pp. 275-286
-
-
Aoki, T.O.1
David, N.B.2
Minchiotti, G.3
Saint-Etienne, L.4
Dickmeis, T.5
Persico, G.M.6
Strahle, U.7
Mourrain, P.8
Rosa, F.M.9
-
44
-
-
33750713346
-
GeneTools - Application for functional annotation and statistical hypothesis testing
-
1630634 17062145 10.1186/1471-2105-7-470
-
Beisvag V Junge F Bergum H Jolsum L Lydersen S Gunther CC Ramampiaro H Langaas M Sandvik A Laegreid A GeneTools - application for functional annotation and statistical hypothesis testing BMC Bioinformatics 2006 7:470 1630634 17062145 10.1186/1471-2105-7-470
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 470
-
-
Beisvag, V.1
Junge, F.2
Bergum, H.3
Jolsum, L.4
Lydersen, S.5
Gunther, C.C.6
Ramampiaro, H.7
Langaas, M.8
Sandvik, A.9
Laegreid, A.10
-
45
-
-
0027453569
-
Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos
-
8306883
-
Thisse C Thisse B Schilling TF Postlethwait JH Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos Development 1993 119:1203-1215 8306883
-
(1993)
Development
, vol.119
, pp. 1203-1215
-
-
Thisse, C.1
Thisse, B.2
Schilling, T.F.3
Postlethwait, J.H.4
|