Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis

Development

Volumn 133, Issue 17, 2006, Pages 3429-3440

  Bissonauth, Vickram ^a   Roy, Sohie ^a   Gravel, Mathieu ^a   Guillemette, Stéphanie ^a   Charron, Jean ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Conditional deletion; Labyrinthine morphogenesis; Map kinase cascade; MAP2K1; Mouse; Placenta; Syncytiotrophoblast

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LINEAGE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHORION; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; FETAL WELL BEING; FETUS MEMBRANE; GENE DELETION; GENE FUNCTION; MOUSE; NONHUMAN; PHENOTYPE; PLACENTA CIRCULATION; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; SYNCYTIOTROPHOBLAST; TETRAPLOIDY;

ALLELES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CHIMERA; EMBRYO; EMBRYO, MAMMALIAN; FEMALE; GENOTYPE; IN SITU HYBRIDIZATION; MAP KINASE KINASE 1; MICE; MICE, MUTANT STRAINS; PLACENTA; SIGNAL TRANSDUCTION;

EID: 33749389685     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02526     Document Type: Article

References (59)

1. Adams, R. H., Porras, A., Alonso, G., Jones, M., Vintersten, K., Panelli, S., Valladares, A., Perez, L., Klein, R. and Nebreda, A. R. (2000). Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol. Cell 6, 109-116.
2. Aubin, I., Déry, U., Lemieux, M., Chailler, P and Jeannotte, L. (2002). Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Development 129, 4075-4087.
3. Ballif, B. A. and Blenis, J. (2001). Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ. 12, 397-408.
4. Bélanger, L. F., Roy, S., Tremblay, M., Brott, B., Steff, A. M., Mourad, W., Hugo, P., Erikson, R. and Charron, J. (2003). Mek2 is dispensable for mouse growth and development. Mol. Cell. Biol. 23, 4778-4787.
5. Blaschke, F., Stawowy, P., Goetze, S., Hintz, O., Grafe, M., Kintscher, U., Fleck, E. and Graf, K. (2002). Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 296, 890-896.
6. Brott, B. K., Alessandrini, A., Largaespada, D. A., Copeland, N. G., Jenkins, N. A., Crews, C. M. and Erikson, R. L. (1993). MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues. Cell Growth Differ 4, 921-929.
7. Brunet, A., Brondello, J. M., L'Allemain, G., Lenormand, P., McKenzie, F., Pages, G. and Pouyssegur, J. (1995). MAP kinase module: role in the control of cell proliferation. C. R. Seances. Soc. Biol. Fil. 189, 43-57.
8. Cano, E. and Mahadevan, L. C. (1995). Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20, 117-122.
9. Catling, A. D., Schaeffer, H. J., Reuter, C. W., Reddy, G. R. and Weber, M. J. (1995). A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function. Mol. Cell. Biol. 15, 5214-5225.
10. Coan, R M., Ferguson-Smith, A. C. and Burton, G. J. (2005). Ultrastructural changes in the interhaemal membrane and junctional zone of the murine chorioallantoic placenta across gestation. J. Anat. 207, 783-796.
11. Coles, L. C. and Shaw, P. E. (2002). PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. Oncogene 21, 2236-2244.
12. Conrad, P. W., Millhorn, D. E. and Beitner-Johnson, D. (2000). Hypoxia differentially regulates the mitogen- and stress-activated protein kinases. Role of Ca2+/CaM in the activation of MAPK and p38 gamma. Adv. Exp. Med. Biol. 475, 293-302.
13. Corson, L. B., Yamanaka, Y., Lai, K. M. and Rossant, J. (2003). Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130, 4527-4537.
14. Crews, C. M., Alessandrini, A. and Erikson, R. L. (1992). The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 258, 478-480.
15. Cross, J. C. (2000). Genetic insights into trophoblast differentiation and placental morphogenesis. Semin. Cell Dev. Biol. 11, 105-113.
16. Dang, A., Frost, J. A. and Cobb, M. H. (1998). The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells. J. Biol. Chem. 273, 19909-19913.
17. Eblen, S. T., Slack, J. K., Weber, M. J. and Catling, A. D. (2002), Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. Mol. Cell. Biol. 22, 6023-6033.
18. Fan, B., Wang, Y. X, Yao, T. and Zhu, Y. C. (2005). p38 Mitogen-activated protein kinase mediates hypoxia-induced vascular endothelial growth factor release in human endothelial cells. Sheng Li Xue Bao 57, 13-20.
19. Fukuda, M., Gotoh, Y. and Nishida, E. (1997). Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 16, 1901-1908.
20. Giroux, S. and Charron, J. (1998). Defective development of the embryonic liver in N-myc-deficient mice. Dev. Biol. 195, 16-28.
21. Giroux, S., Tremblay. M., Bernard, D., Cardin-Girard, J. F., Aubry, S., Larouche, L., Rousseau, S., Huot, J., Landry, J., Jeannotte, L. et al. (1999). Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta. Curr. Biol. 9, 369-372.
22. Gopalbhai, K., Jansen, G., Beauregard, G., Whiteway, M., Dumas, F., Wu, C. and Meloche, S. (2003). Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1. J. Biol. Chem. 278, 8118-8125.
23. Hatano, N., Mori, Y., Oh-hora, M., Kosugi, A., Fujikawa, T., Nakai, N., Niwa, H., Miyazaki, J., Hamaoka, T and Ogata, M. (2003). Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells 8, 847-856.
24. Hayashi, S., Lewis, P., Pevny, L. and McMahon, A. P. (2002). Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expr. Patterns 2, 93-97.
25. Hemberger, M. and Cross, J. C. (2001). Genes governing placental development. Trends Endocrinol Metab. 12, 162-168.
26. Hsu, J. C. and Perrimon, N. (1994). A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases. Genes Dev. 8, 2176-2187.
27. Huynh, H. T., Nguyen, T. T., Chow, P. K., Tan, P. H., Soo, K. C. and Tran, E. (2003). Over-expression of MEK-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis. BMC Gastroenterol. 3, 19.
28. Johnson, G. L. and Vaillancourt, R. R. (1994). Sequential protein kinase reactions controlling cell growth and differentiation. Curr. Opin. Cell Biol. 6, 230-238.
29. Kornfeld, K., Guan, K. L. and Horvitz, H. R. (1995). The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes Dev 9, 756-768.
30. Lakso, M., Pichel, J. G., Gorman, J. R.. Sauer, B., Okamoto, Y., Lee, E., Alt, F. W. and Westphal, H. (1996). Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl. Acad. Sci. USA 93, 5860-5865.
31. Littell, R. C., Henry, P. R. and Ammerman, C. B. (1998). Statistical analysis of repeated measures data using SAS procedures. J. Anim. Sci. 76, 1216-1231.
32. Matsubara, S., Tamada, T, Sayama, M. and Saito, T. (1993). Studies on the permeability and enzyme-cytochemistry of the mouse hemotrichorial placenta. Asia Oceania J. Obstet Gynaecol. 19, 441-447.
33. Mudgett, J. S., Ding, J., Guh-Siesel, L., Chartrain, N. A., Yang, L., Gopal, S. and Shen, M. M. (2000). Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc. Natl. Acad. Sci. USA 97, 10454-10459.
34. Nagy, A., Rossant. J., Nagy, R., Wanda, A.-N. and Roder, J. C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl. Acad. Sci. USA 90, 8424-8428.
35. Nantel, A., Mohammad-Ali, K., Sherk, J., Posner, B. I. and Thomas, D. Y. (1998). Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases. J. Biol. Chem. 273, 10475-10484.
36. Pages, G., Lenormand, P., L'Allemain, G., Chambard, J. C., Meloche, S. and Pouyssegur, J. (1993). Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc. Natl. Acad. Sci. USA 90, 8319-8323.
37. Pages, G., Guerin, S., Grall, D., Bonino, F., Smith, A., Anjuere, F., Auberger, P. and Pouyssegur, J. (1999). Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286, 1374-1377.
38. Papin, C., Denouel, A., Calothy, G. and Eychene, A. (1996). identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system. Oncogene 12, 2213-2221.
39. Rossant, J. (2001). Stem cells from the Mammalian blastocyst. Stem Cells 19, 477-482.
40. Rossant, J. and Cross, J. C. (2001). Placental development: lessons from mouse mutants. Nat. Rev. Genet. 2, 538-548.
41. Rousseau, S., Houlle, F., Landry, J. and Huot, J. (1997). p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15, 2169-2177.
42. Russell, M., Lange-Carter, C. A. and Johnson, G. L. (1995). Regulation of recombinant MEK1 and MEK2b expressed in Escherichia coli. Biochemistry 34, 6611-6615.
43. Saba-EI-Leil, M. K., Vella, F. D., Vernay, B., Voisin, L., Chen, L., Labrecque, N., Ang, S. L. and Meloche, S. (2003). An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep. 4, 964-968.
44. Seger, R. and Krebs, E. G. (1995). The MAPK signaling cascade. FASEB J. 9, 726-735.
45. Simmons, D. G. and Cross, J. C. (2005). Determinants of trophoblast lineage and cell subtype specification in the mouse placenta. Dev. Biol. 284, 12-24.
46. Stecca. B., Nait-Oumesmar, B., Kelley, K. A., Voss, A. K., Thomas, T. and Lazzarini, R. A. (2002). Gcm1 expression defines three stages of chorio-allantoic interaction during placental development. Mech. Dev 115, 27-34.
47. Tamura, K., Sudo, T., Senftleben, U., Dadak, A. M., Johnson, R. and Karin, M. (2000). Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102, 221-231.
48. Tanaka, S., Kunath, T., Hadjantonakis, A. K., Nagy, A. and Rossant, J. (1998). Promotion of trophoblast stem cell proliferation by FGF4. Science 282, 2072-2075.
49. Umbhauer, M., Marshall, C. J., Mason, C. S., Old, R. W. and Smith, J. C. (1995), Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62.
50. von Gise, A., Lorenz, P., Wellbrock, C., Hemmings, B., Berberich-Siebelt, F., Rapp, U. R. and Troppmair, J. (2001). Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals. Mol. Cell. Biol. 21, 2324-2336.
51. Watson, E. D. and Cross, J. C. (2005). Development of structures and transport functions in the mouse placenta. Physiology Bethesda 20, 180-193.
52. Wu, J., Wong, W. W., Khosravi, F., Minden, M. D. and Penn, L. Z. (2004). Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis. Cancer Res. 64, 6461-6468.
53. Wu, L., de Bruin, A., Saavedra, H. I., Starovic, M., Trimboli, A., Yang, Y., Opavska, J., Wilson, P., Thompson, J. C., Ostrowski, M. C. et al. (2003). Extra-embryonic function of Rb is essential for embryonic development and viability. Nature 421, 942-947.
54. Wu, Y., Han, M. and Guan, K. L. (1995). MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events. Genes Dev 9, 742-755.
55. Xu, S., Khoo, S., Dang, A., Witt, S., Do, V., Zhen, E., Schaefer, E. M. and Cobb, M. H. (1997). Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism. Mol Endocrinol. 11, 1618-1625.
56. Yang, J., Boerm, M., McCarty, M., Bucana, C., Fidler, I. J., Zhuang, Y. and Su, B. (2000). Mekk3 is essential for early embryonic cardiovascular development. Nat. Genet. 24, 309-313.
57. Yu, C., Rahmani, M., Almenara, J., Sausville, E. A., Dent, P. and Grant S. (2004). Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process. Oncogene 23, 1364-1376.
58. Zanke, B. W., Rubie, E. A., Winnett, E., Chan, J., Randall, S., Parsons, M., Boudreau, K., McInnis, M., Yan, M., Templeton, D. J. et al. (1996). Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. J. Biol. Chem. 271, 29876-29881.
59. Zhang, W. and Liu, H. T. (2002). MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res. 12, 9-18.