Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background

Pharmacogenomics Journal

Volumn 8, Issue 3, 2008, Pages 209-219

  Loukola, A ^a,b   Broms, U ^a,b   Maunu, H ^a,b   Widen E ^b   Heikkila K ^b   Siivola, M ^b   Salo, A ^a,b   Pergadia, M L ^c   Nyman, E ^a   Sammalisto, S ^a   Perola, M ^a   Agrawal, A ^c   Heath, A C ^c   Martin, N G ^d   Madden, P A F ^c   Peltonen, L ^a,b   Kaprio, J ^a,b  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOLISM; ARTICLE; CHROMOSOME 10Q; CHROMOSOME 11P; CHROMOSOME 7Q; CHROMOSOME ABERRATION; COHORT ANALYSIS; COMORBIDITY; CORRELATION ANALYSIS; DRINKING BEHAVIOR; FEMALE; FINLAND; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC LINKAGE; GENETIC RISK; GENOME ANALYSIS; HOMOGENATE; HUMAN; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SMOKING; TOBACCO DEPENDENCE; TWINS;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; GENOTYPE; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; MIDDLE AGED; PHENOTYPE; SMOKING; TOBACCO USE DISORDER; TWINS;

NICOTIANA TABACUM;

EID: 44049103123     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500464     Document Type: Article

References (62)

1. Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ, 2004; 328: 1519-1528.
2. Shafey O, Dolwick S, Guindon GE (eds). Tobacco Control Country Profiles. American Cancer Society: Atlanta, GA 2003.
3. True WR, Man H, Scherrer JF, Madden PAF, Bucholz KK, Heath AC et al Common genetic vulnerability for nicotine and alcohol dependence in men. Arch Gen Psychiatry 1999; 56: 655-661.
4. Kendler KS, Neale MC, Sullivan P, Corey LA, Gardner CO, Prescott CA. A population-based twin study in women of smoking initiation and nicotine dependence. Psychol Med 1999; 29: 299-308.
5. Lessov CN, Martin NG, Statham DJ, Todorov AA, Slutske WS, Bucholz KK et al. Defining nicotine dependence for genetic research: Evidence from Australian twins. Psychol Med 2004; 34: 865-879.
6. Maes HH, Sullivan PF, Bulik CM, Neale MC, Prescott CA, Eaves LJ et al A twin study of genetic and environmental influences on tobacco initiation,. regular tobacco use and nicotine dependence. Psychol Med 2004, 34: 1251-1261.
7. Vink JM, Beem AL, Posthuma D, Neale MC, Willemsen G, Kendler KS et al Linkage analysis of smoking initiation and quantity in Dutch sibling pairs. Pharmacogenomics J 2004; 4: 274-282, Erratum in: Pharmacogenomics J 2004; 4: 345-346.
8. Hämäläinen J, Kaprio J, Isometsä E, Heikkinen M, Poikolainen, Lindeman S et al. Cigarette smoking, alcohol intoxication and major depressive episode in a representative population sample. J Epidemiol Community Health 2001; 55: 573-576.
9. Johnson EO, Rhee SH, Chase GA, Breslau N. Comorbidity of depression with levels of smoking: An exploration of the shared familial risk hypothesis. Nicotine Tob Res 2004; 6: 1029-1038.
10. Straub RE, Sullivan PF, Ma Y, Myakishev MV, Harris-Kerr C, Wormley B et al. Susceptibility genes for nicotine dependence: A genome scan and follow-up in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Mol Psychiatry 1999; 4: 129-144.
11. Sullivan PF, Neale BM, van den Oord E, Miles MF, Neale MC, Bulik CM et al. Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics. Am J Med Genet B Neumpsychiatr Genet 2004; 126: 23-36.
12. Swan GE, Hops H, Wilhelmsen KC, Lessov-Schlaggar CN, Cheng LS-C, Hudmon KS et al. A genome-vvide screen for nicotine dependence susceptibility loci. Am J Med Genet B Neuropsychiatr Gehet 2006; 141B: 358-360.
13. Li MD, Payne TJ, Ma JZ, Lou XY, Zhang D, Dupont RT et al. A genomewide search finds major of susceptibility loci nicotine dependence on chromosome 10 in African Americans. Am J Genet 2006; 79: 745-751.
14. Duggirala R, Almasy L, Blangero J. Smoking behavior is under the influence of a major quantitative trait locus on human chromosome Sq. Genet Epidemial 1999; 17: S139-S144.
15. Li MD, Ma JZ, Cheng R, Dupont RD, Williams NJ, Crews KM et al. A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet 2003; 4: S103-S107.
16. Morley KI, Medland SE, Ferreira MA, Lynskey MT, Montgomery GW, Heath AC et al. A possible smoking susceptibility locus on chromosome 11p12: Evidence from sex-limitation linkage analyses in a sample of Australian twin families. Behav Genet 2006, 36: 87-99.
17. Gelemter J, Liu X, Hesselbrock V, Page GP, Goddard A, Zhang H. Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. Am J Med Genet B Neumpsychiatr Genet 2004; 128: 94-101.
18. Bierut LI, Rice JP, Goate A, Hinrichs AL, Saccone NL, Foroud T et al A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in sabitance depepcience. Am J Med Genet A 2004; 124: 19-27.
19. Kaprio J, Koskenvuo M, Sama S. Cigarette smoking, use of alcohol, and leisure-time physical activity among same-sexed adult male twins. Prog Clin Biol Res 1981; 69: 37-46.
20. Istvan J, Matarazzo JD. Tobacco, alcohol, and caffeine use: A review of their interrelationships. Psychol Bull 1984; 95: 301-326.
21. Maletzky BM, Klotter J. Smoking and alcoholism. Am J Psychiatry 1974; 131: 445-447.
22. Kaprio J, Hammar N, Koskenvuo M, Floderus-Myrhed B, Langinvainio H, Sama S. Cigarette smoking and alcohol use in Finland and Sweden: A cross-national twin study. Int J Epidemiol 1982; 11: 378-386.
23. Battjes RJ. Smoking as an issue in alcohol and drug abuse treatment. Addict Behav 1988; 13: 225-230.
24. Swan GE, Carmelli D, Cardon LR. Heavy consumption of cigarettes, alcohol and coffee in male twins. J Stud Alcohol 1997; 58: 182-190.
25. Madden PA, Bucholz KK, Martin NG, Heath AC. Smoking and the genetic contribution to alcohol-dependence risk. Alcohol Res Health 2000; 24: 209-214.
26. Batel P, Pessione F, Maitre C, Rueff B. Relationship between alcohol and tobacco dependencies among alcoholics who smoke. Addiction 1995; 90: 977-980.
27. Helakorpi S, Patja K, Präattälä R, Uutela A. Suomalaisen aikuisväestön terveyskäyttäytyminen ja terveys, kevät 2005., Health Behavior and Health among the Finnish Adult Population, Spring 2005. Kansantervey-slajtoksen julkaisuja B 118/2005 Publications of the National Public Health Institute B 18/2005: Helsinki, 2005.
28. Warner KE, Burns DM. Hardening and the hard-core sruoker: Concepts, evidence, and implications. Nicotine Tob Res 2003; 5: 37-48.
29. Goode EL, Badzioch MD, Kim H, Gagnon F, Rozek LS, Edwards KL et al Framingham Heart Study Multiple genome-wide analyses of smoking behavior in the Framingham Heart Study. BMC Genet 2003; 4: S102.
30. Bergen AW, Yang XR, Bai Y, Beerman MB, Goldstein AM, Goldin LR, Framingham Heart Study. Genomic regions linked to alcohol consumption in the Framingham Heart Study. BMC Genet 2003; 4(Suppl 1): S101.
31. Bergen AW, Korczak JF, Weissbecker KA, Goldstein AM. A genome-wide search for loci contributing to smoking and alcoholism. Genet Epidemiol 1999; 17: S55-S60.
32. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Press: Washington, DC, 1994.
33. Heatherton TF, Kozlowski LT, Frecker RC, Fagerström K-O. The Fagerström Test for Nicotine Dependence: A revision of the Fagerström Tolerance Questionnaire. Br J Addict 1991; 86: 1119-1127.
34. Heatherton TF, Kozlowski LT, Frecker RC, Rickert W, Robinson J. Measuring the heaviness of smoking: Using self-reported time to the first cigarette of the day and number of cigarettes smoked per day. Br J Addict 1989; 84: 791-799.
35. Peltonen L, Palotie A, Lange K. Use of population isolates for mapping complex traits. Nat Rev Genet 2000; 1: 182-190.
36. Broms U, Silventoinen K, Madden PAF, Heath AC, Kaprio J. Genetic architecture of smoking behaviour: A study of Finnish adult twins. Twin Res Hum Genet 2006, 9: 64-72.
37. Armstrong BK, White E, Saracci R. Principles of exposure measurement in Epidemiology. Monographs in Epidemiology and Biostatistics, vol. 21. Oxford University Press: New York, 1994.
38. Vartiainen E, Seppälä T, Lillsunde P, Puska P. Validation of self reported smoking by serum cotinine measurement in a community-based study. J Epidemiol Community Health 2002; 56: 167-170.
39. Madden PA, Heath AC, Pedersen NL, Kaprio J, Koskenvuo MJ, Martin NG. The genetics of smoking persistence in men and women: A multicultural study. Behav Genet 1999; 29: 423-431.
40. Madden PA, Pedersen NL, Kaprio J, Koskenvuo MJ, Martin NG. The epidemiology and genetics of smoking initiation and persistence: crosscultural comparisons of twin study results. Twin Res 2004; 7: 82-97.
41. Fagerström KO. Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. Addict Behav 1978; 3: 235-241.
42. Fagerström KO, Schneider NG. Measuring nicotine dependence: A review of the Fagerström Tolerance Questionnaire. J Behav Med 1989; 12: 159-182.
43. CDC. Annual smoking-attributable mortality, years of potential life lost, and productivity losses - United States, 1997-2001. MMWR 2005; 54: 625-628.
44. Haukkala A, Laaksonen M, Uutela A. Smokers who do not want to quit - is consonant smoking related to lifestyle and socioeconomic factors? Scand J Public Health 2001; 29: 226-232.
45. Helakorpi S, Berg M, Uutela A, Puska P. Suomalaisen aikuisväestön terveyskäyttäytyminen, kevät 1994. Health behaviour among Finnish adult population, Spring 1994. Kansanterveyslaitoksen julkaisuja B 8/1994 Publications of the National Public Health Institute B 8/1994: Helsinki, 1994.
46. Moolchan ET, Radzius A, Epstein DH, Uhl G, Gorelick DA, Cadet JL et al. The Fagerström Test for Nicotine Dependence and the Diagnostic Interview Schedule. Addict Behav 2002; 27: 101-113.
47. Etter JF. A comparison of the content-, construct- and predictive validity of the cigarette dependence scale and the Fagerström test for nicotine dependence. Drug Alcohol Depend 2005; 77: 259-268.
48. Ekelund J, Lichtermann D, Hovatta I, Ellonen P, Suvisaari J, Terwilliger JD et al. Genome-wide scan for schizophrenia in the Finnish population: Evidence for a locus on chromosome 7q22. Hum Mol Genet 2000; 9: 1049-1057.
49. Madden PA, Heath AC. Shared genetic vulnerability in alcohol and cigarette use, and dependence. Alcohol Clin Exp Res 2002; 26 1919-1921.
50. Ye Y, Zhong X, Zhang H. A genome-wide tree- and forest-based association analysis of comorbidity of alcoholism and smoking. BMC Genet 2005; 6: S135.
51. Kaprio J, Koskenvuo M. Genetic and environmental factors in complex diseases: The Older Finnish Twin Cohort. Twin Res 2002; 5: 358-365.
52. Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Numberger Jr Ji et al. A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA. J Stud Alcohol 1994; 55: 149-158.
53. Cottler LB, Robins LN, Grant BF, Blaine J, Towle LH, Wittchen HU et al. The CIDI-core substance abuse and dependence questions: cross-cultural and nosological issues. The-WHO/ADAMHA field trial. Br J Psychiatry 1991; 159: 653-658.
54. Kauhanen J, Kaplan GA, Goldberg DE, Salonen JT. Beer binging and mortality: Results from the Kuopio ischaemic heart disease risk factor study, a prospective population based study. BMJ 1997, 315: 846-851.
55. Järvenpää T, Rinne JO, Koskenvuo M, Räihä I, Kaprio J. Binge drinking in midlife and dementia risk. Epidemiology 2005; 16: 766-771.
56. O'Connell JR, Weeks DE. PedCheck: A program for identifying genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63 259-266.
57. Abecasis GR, Chemy SS, Cookson WO, Cardon LR. GRR: Graphical representation of relationship errors. Bioinformatics 2001; 17 742-743.
58. Kong A, Gudbjartsson DF, Sainz J, Jonsdottir GM, Gudjonsson SA, Richardsson B et al. A high-resolution recombination map of the human genome. Nat Genet 2002; 31: 241-247.
59. Lichter JB, Barr CL, Kennedy JL, Van Tol HH, Kidd KK, Livak KJ. A hypervariable segment in the human dopimine receptor D4 (DRD4) gene. Hum Mol Genet 1993; 2: 767-773.
60. Abecasis GR, Chemy SS, Cookson WO, Cardon LR. Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002; 30: 97-101.
61. Hiekkalinna T, Terwilliger JD, Sammalisto S, Peltonen L, Perola M. AUTOGSCAN: Powerful tools for automated genome-wide linkage and linkage disequilibrium analysis. Twin Res Hum Genet 2005; 8: 16-21.
62. Göring HHH, Terwilliger JD. Linkage analysis in the presence of errors IV: Joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when & mode of inheritance cannot be accurately specified. Am J Hum Genet 2000; 66: 1310-1327.