SCOPUS 정보 검색 플랫폼

Molecular BioSystems

Volumn 4, Issue 6, 2008, Pages 629-642

Targeting telomerase and telomeres: A click chemistry approach towards highly selective G-quadruplex ligands

(6) Moorhouse, Adam D a,b Haider, Shozeb a Gunaratnam, Mekala a Munnur, Deeksha a Neidle, Stephen a Moses, John E a,b

a UNIVERSITY OF LONDON (United Kingdom)

b UNIVERSITY OF NOTTINGHAM (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DI(1,2,3 TRIAZOL 4 YL)BENZENE; 1,3-DI(1,2,3-TRIAZOL-4-YL)BENZENE; BENZENE DERIVATIVE; DNA; GUANINE QUADRUPLEX; LIGAND; TELOMERASE; TRIAZOLE DERIVATIVE;

ARTICLE; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; METABOLISM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TELOMERE;

BENZENE DERIVATIVES; BINDING SITES; COMPUTER SIMULATION; DNA; G-QUADRUPLEXES; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TELOMERASE; TELOMERE; TRIAZOLES;

EID: 43949111648 PISSN: 1742206X EISSN: 17422051 Source Type: Journal
DOI: 10.1039/b801822g Document Type: Article

Times cited : (38)

References (64)

1
- 0035929353
- -673
- E. H. Blackburn Cell 2001 106 661 673
- (2001) Cell , vol.106 , pp. 661
- Blackburn, E.H.¹

2
- 0013462065
- -6626
- R. K. Moyzis J. M. Buckingham L. S. Cram M. Dani L. L. Deaven M. D. Jones J. Meyne R. L. Ratliff J. R. Wu Proc. Natl. Acad. Sci. U. S. A. 1988 85 6622 6626
- (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 6622
- Moyzis, R.K.¹ Buckingham, J.M.² Cram, L.S.³ Dani, M.⁴ Deaven, L.L.⁵ Jones, M.D.⁶ Meyne, J.⁷ Ratliff, R.L.⁸ Wu, J.R.⁹

3
- 0031000884
- -666
- V. L. Makarov Y. Hirose J. P. Langmore Cell 1997 88 657 666
- (1997) Cell , vol.88 , pp. 657
- Makarov, V.L.¹ Hirose, Y.² Langmore, J.P.³

4
- 0030982721
- -3714
- R. McElligott R. J. Wellinger EMBO J. 1997 16 3705 3714
- (1997) EMBO J. , vol.16 , pp. 3705
- McElligott, R.¹ Wellinger, R.J.²

5
- 0030731928
- -2809
- W. E. Wright V. M. Tesmer K. E. Huffman S. D. Levene J. W. Shay Genes Dev. 1997 11 2801 2809
- (1997) Genes Dev. , vol.11 , pp. 2801
- Wright, W.E.¹ Tesmer, V.M.² Huffman, K.E.³ Levene, S.D.⁴ Shay, J.W.⁵

6
- 31544466516
- -435
- W. Chai Q. Du J. W. Shay W. E. Wright Mol. Cell 2006 21 427 435
- (2006) Mol. Cell , vol.21 , pp. 427
- Chai, W.¹ Du, Q.² Shay, J.W.³ Wright, W.E.⁴

7
- 0025279931
- -460
- C. B. Harley A. B. Futcher C. W. Greider Nature 1990 345 458 460
- (1990) Nature , vol.345 , pp. 458
- Harley, C.B.¹ Futcher, A.B.² Greider, C.W.³

8
- 0036562687
- -393
- S. Neidle G. Parkinson Nat. Rev. Drug Discovery 2002 1 383 393
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 383
- Neidle, S.¹ Parkinson, G.²

9
- 33745679352
- -584
- J. W. Shay W. E. Wright Nat. Rev. Drug Discovery 2006 5 577 584
- (2006) Nat. Rev. Drug Discovery , vol.5 , pp. 577
- Shay, J.W.¹ Wright, W.E.²

10
- 18044391665
- -979
- L. R. Kelland Eur. J. Cancer 2005 41 971 979
- (2005) Eur. J. Cancer , vol.41 , pp. 971
- Kelland, L.R.¹

11
- 0024325562
- -529
- G. B. Morin Cell 1989 59 521 529
- (1989) Cell , vol.59 , pp. 521
- Morin, G.B.¹

12
- 0028564951
- -2015
- N. W. Kim M. A. Piatyszek K. R. Prowse C. B. Harley M. D. West P. L. Ho G. M. Coviello W. E. Wright S. L. Weinrich J. W. Shay Science 1994 266 2011 2015
- (1994) Science , vol.266 , pp. 2011
- Kim, N.W.¹ Piatyszek, M.A.² Prowse, K.R.³ Harley, C.B.⁴ West, M.D.⁵ Ho, P.L.⁶ Coviello, G.M.⁷ Wright, W.E.⁸ Weinrich, S.L.⁹ Shay, J.W.¹⁰

13
- 0028262113
- -2904
- C. M. Counter H. W. Hirte S. Bacchetti C. M. Harley Proc. Natl. Acad. Sci. U. S. A. 1994 91 2900 2904
- (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 2900
- Counter, C.M.¹ Hirte, H.W.² Bacchetti, S.³ Harley, C.M.⁴

14
- 0031010342
- -791
- J. W. Shay S. Bacchetti Eur. J. Cancer 1997 33 787 791
- (1997) Eur. J. Cancer , vol.33 , pp. 787
- Shay, J.W.¹ Bacchetti, S.²

15
- 34247188473
- -1024
- E. Hiyama K. Hiyama Br. J. Cancer 2007 96 1020 1024
- (2007) Br. J. Cancer , vol.96 , pp. 1020
- Hiyama, E.¹ Hiyama, K.²

16
- 0032828652
- -1170
- W. C. Hahn S. A. Stewart M. W. Brooks S. G. York E. Eaton A. Kurachi R. L. Beijersbergen J. H. M. Knoll M. Meyerson R. A. Weinberg Nat. Med. 1999 10 1164 1170
- (1999) Nat. Med. , vol.10 , pp. 1164
- Hahn, W.C.¹ Stewart, S.A.² Brooks, M.W.³ York, S.G.⁴ Eaton, E.⁵ Kurachi, A.⁶ Beijersbergen, R.L.⁷ Knoll, J.H.M.⁸ Meyerson, M.⁹ Weinberg, R.A.¹⁰

17
- 0033568462
- -2399
- X. Zhang V. Mar W. Zhou L. Harrington M. O. Robinson Genes Dev. 1999 13 2388 2399
- (1999) Genes Dev. , vol.13 , pp. 2388
- Zhang, X.¹ Mar, V.² Zhou, W.³ Harrington, L.⁴ Robinson, M.O.⁵

18
- 4243937106
- -6968
- K. Damm U. Hemmann P. Garin-Chesa N. Hauel I. Kauffmann H. Priepke C. Niestroj C. Daiber B. Enenkel B. Guilliard I. Lauritsch E. Muller E. Pascolo G. Sauter M. Pantic U. M. Martens C. Wenz J. Lingner N. Kraut W. J. Rettig A. Schnapp EMBO J. 2001 20 6958 6968
- (2001) EMBO J. , vol.20 , pp. 6958
- Damm, K.¹ Hemmann, U.² Garin-Chesa, P.³ Hauel, N.⁴ Kauffmann, I.⁵ Priepke, H.⁶ Niestroj, C.⁷ Daiber, C.⁸ Enenkel, B.⁹ Guilliard, B.¹⁰ Lauritsch, I.¹¹ Muller, E.¹² Pascolo, E.¹³ Sauter, G.¹⁴ Pantic, M.¹⁵ Martens, U.M.¹⁶ Wenz, C.¹⁷ Lingner, J.¹⁸ Kraut, N.¹⁹ Rettig, W.J.²⁰ Schnapp, A.²¹ more..

19
- 18544364628
- -15572
- E. Pascolo C. Wenz J. Lingner N. Hauel H. Priepke I. Kauffmann P. Garin-Chesa W. J. Rettig K. Damm A. Schnapp J. Biol. Chem. 2002 277 15566 15572
- (2002) J. Biol. Chem. , vol.277 , pp. 15566
- Pascolo, E.¹ Wenz, C.² Lingner, J.³ Hauel, N.⁴ Priepke, H.⁵ Kauffmann, I.⁶ Garin-Chesa, P.⁷ Rettig, W.J.⁸ Damm, K.⁹ Schnapp, A.¹⁰

20
- 0033455559
- -14281
- B.-S. Herbert A. E. Pitts S. I. Baker S. E. Hamilton W. E. Wright J. W. Shay D. R. Corey Proc. Natl. Acad. Sci. U. S. A. 1999 96 14276 14281
- (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 14276
- Herbert, B.-S.¹ Pitts, A.E.² Baker, S.I.³ Hamilton, S.E.⁴ Wright, W.E.⁵ Shay, J.W.⁶ Corey, D.R.⁷

21
- 0037148329
- -637
- D. R. Corey Oncogene 2002 21 631 637
- (2002) Oncogene , vol.21 , pp. 631
- Corey, D.R.¹

22
- 0035283512
- -120
- L. K. White W. E. Wright J. W. Shay Trends Biotechnol. 2001 19 114 120
- (2001) Trends Biotechnol. , vol.19 , pp. 114
- White, L.K.¹ Wright, W.E.² Shay, J.W.³

23
- 0036667390
- -423
- E. M. Rezler D. J. Bearss L. H. Hurley Curr. Opin. Pharmacol. 2002 2 415 423
- (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 415
- Rezler, E.M.¹ Bearss, D.J.² Hurley, L.H.³

24
- 0036782884
- For a comprehensive review see: -265
- J. W. Shay W. E. Wright Cancer Cell 2002 2 257 265
- (2002) Cancer Cell , vol.2 , pp. 257
- Shay, J.W.¹ Wright, W.E.²

25
- 37049004147
- -155
- A. De Cian L. Lacroix C. Douarre N. Temime-Smaali C. Trentesaux J.-F. Riou J.-L. Mergny Biochimie 2008 90 131 155
- (2008) Biochimie , vol.90 , pp. 131
- De Cian, A.¹ Lacroix, L.² Douarre, C.³ Temime-Smaali, N.⁴ Trentesaux, C.⁵ Riou, J.-F.⁶ Mergny, J.-L.⁷

26
- 0031727943
- -1367
- J.-L. Mergny C. Hélène Nat. Med. 1998 4 1366 1367
- (1998) Nat. Med. , vol.4 , pp. 1366
- Mergny, J.-L.¹ Hélène, C.²

27
- 0034176194
- -142
- H. Han L. H. Hurley Trends Pharmacol. Sci. 2000 21 136 142
- (2000) Trends Pharmacol. Sci. , vol.21 , pp. 136
- Han, H.¹ Hurley, L.H.²

28
- 0034122135
- -471
- S. M. Kerwin Curr. Pharm. Des. 2000 6 441 471
- (2000) Curr. Pharm. Des. , vol.6 , pp. 441
- Kerwin, S.M.¹

29
- 43949099993
- C. Bailly, W.D. Wilson, John Wiley, Weinheim, Germany, pp 337-359
- S. M. Haider, G. N. Parkinson, M. A. Read and S. Neidle, in DNA and RNA Binders, ed., C. Bailly,,, W.D. Wilson,, John Wiley, Weinheim, Germany, 2002, pp 337-359
- (2002) DNA and RNA Binders, Ed.
- Haider, S.M.¹ Parkinson, G.N.² Read, M.A.³ Neidle In, S.⁴

30
- 0028173870
- -730
- J. R. Williamson Annu. Rev. Biophys. Biomol. Struct. 1994 23 703 730
- (1994) Annu. Rev. Biophys. Biomol. Struct. , vol.23 , pp. 703
- Williamson, J.R.¹

31
- 0035018021
- -628
- T. Simonsson Biol. Chem. 2001 382 621 628
- (2001) Biol. Chem. , vol.382 , pp. 621
- Simonsson, T.¹

32
- 0025877846
- -720
- A. M. Zahler J. R. Williamson T. R. Cech D. M. Prescott Nature 1991 350 718 720
- (1991) Nature , vol.350 , pp. 718
- Zahler, A.M.¹ Williamson, J.R.² Cech, T.R.³ Prescott, D.M.⁴

33
- 13944272246
- -1496
- A. M. Burger F. Dai C. M. Schultes A. P. Reszka M. J. Moore J. A. Double S. Neidle Cancer Res. 2005 65 1489 1496
- (2005) Cancer Res. , vol.65 , pp. 1489
- Burger, A.M.¹ Dai, F.² Schultes, C.M.³ Reszka, A.P.⁴ Moore, M.J.⁵ Double, J.A.⁶ Neidle, S.⁷

34
- 10744221442
- -4476
- R. J. Harrison J. Cuesta G. Chessari M. A. Read S. K. Basra A. P. Reszka J. Morrell S. M. Gowan C. M. Incles F. A. Tanious W. D. Wilson L. R. Kelland S. Neidle J. Med. Chem. 2003 46 4463 4476
- (2003) J. Med. Chem. , vol.46 , pp. 4463
- Harrison, R.J.¹ Cuesta, J.² Chessari, G.³ Read, M.A.⁴ Basra, S.K.⁵ Reszka, A.P.⁶ Morrell, J.⁷ Gowan, S.M.⁸ Incles, C.M.⁹ Tanious, F.A.¹⁰ Wilson, W.D.¹¹ Kelland, L.R.¹² Neidle, S.¹³

35
- 33748701981
- -5725
- T. Tauchi K. Shin-Ya G. Sashida M. Sumi S. Okabe J. H. Ohyashiki K. Ohyashiki Oncogene 2006 25 5719 5725
- (2006) Oncogene , vol.25 , pp. 5719
- Tauchi, T.¹ Shin-Ya, K.² Sashida, G.³ Sumi, M.⁴ Okabe, S.⁵ Ohyashiki, J.H.⁶ Ohyashiki, K.⁷

36
- 0037142071
- -880
- G. N. Parkinson M. P. H. Lee S. Neidle Nature 2002 417 876 880
- (2002) Nature , vol.417 , pp. 876
- Parkinson, G.N.¹ Lee, M.P.H.² Neidle, S.³

37
- 0345098322
- -15027
- A. T. Phan D. J. Patel J. Am. Chem. Soc. 2003 125 15021 15027
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 15021
- Phan, A.T.¹ Patel, D.J.²

38
- 33746600695
- -9970
- K. N. Luu A. T. Phan V. Kuryavyi L. Lacroix D. J. Patel J. Am. Chem. Soc. 2006 128 9963 9970
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 9963
- Luu, K.N.¹ Phan, A.T.² Kuryavyi, V.³ Lacroix, L.⁴ Patel, D.J.⁵

39
- 33646943863
- For example see: -2735
- A. Ambrus D. Chen J. Dai T. Bialis R. A. Jones D. Yang Nucleic Acids Res. 2006 34 2723 2735
- (2006) Nucleic Acids Res. , vol.34 , pp. 2723
- Ambrus, A.¹ Chen, D.² Dai, J.³ Bialis, T.⁴ Jones, R.A.⁵ Yang, D.⁶

40
- 0035942270
- -4849
- M. Read R. J. Harrison B. Romagnoli F. A. Tanious S. H. Gowan A. P. Reszka W. D. Wilson L. R. Kelland S. Neidle Proc. Natl. Acad. Sci. U. S. A. 2001 98 4844 4849
- (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 4844
- Read, M.¹ Harrison, R.J.² Romagnoli, B.³ Tanious, F.A.⁴ Gowan, S.H.⁵ Reszka, A.P.⁶ Wilson, W.D.⁷ Kelland, L.R.⁸ Neidle, S.⁹

41
- 33845573936
- -15973
- A. D. Moorhouse A. M. Santos M. Gunaratnam M. Moore S. Neidle J. E. Moses J. Am. Chem. Soc. 2006 128 15972 15973
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 15972
- Moorhouse, A.D.¹ Santos, A.M.² Gunaratnam, M.³ Moore, M.⁴ Neidle, S.⁵ Moses, J.E.⁶

42
- 0000096835
- -2021
- H. C. Kolb M. G. Finn K. B. Sharpless Angew. Chem., Int. Ed. 2001 40 2004 2021
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 2004
- Kolb, H.C.¹ Finn, M.G.² Sharpless, K.B.³

43
- 0348109450
- -1137
- H. C. Kolb K. B. Sharpless Drug Discovery Today 2003 8 1128 1137
- (2003) Drug Discovery Today , vol.8 , pp. 1128
- Kolb, H.C.¹ Sharpless, K.B.²

44
- 34547272503
- -1262
- J. E. Moses A. D. Moorhouse Chem. Soc. Rev. 2007 36 1249 1262
- (2007) Chem. Soc. Rev. , vol.36 , pp. 1249
- Moses, J.E.¹ Moorhouse, A.D.²

45
- 47649133089
- 10.1002/cmdc.200700334
- A. D. Moorhouse J. E. Moses ChemMedChem. 2008 10.1002/cmdc.200700334
- (2008) ChemMedChem.
- Moorhouse, A.D.¹ Moses, J.E.²

46
- 0037012920
- -3064
- C. W. Tornøe C. Christensen M. Meldal J. Org. Chem. 2002 67 3057 3064
- (2002) J. Org. Chem. , vol.67 , pp. 3057
- Tornøe, C.W.¹ Christensen, C.² Meldal, M.³

47
- 0037099395
- -2599
- V. V. Rostovtsev L. G. Green V. V. Fokin K. B. Sharpless Angew. Chem., Int. Ed. 2002 41 2596 2599
- (2002) Angew. Chem., Int. Ed. , vol.41 , pp. 2596
- Rostovtsev, V.V.¹ Green, L.G.² Fokin, V.V.³ Sharpless, K.B.⁴

48
- 34248363670
- -1811
- K. Barral A. D. Moorhouse J. E. Moses Org. Lett. 2007 9 1809 1811
- (2007) Org. Lett. , vol.9 , pp. 1809
- Barral, K.¹ Moorhouse, A.D.² Moses, J.E.³

49
- 0033514429
- -1581
- J.-L. Mergny Biochemistry 1999 38 1573 1581
- (1999) Biochemistry , vol.38 , pp. 1573
- Mergny, J.-L.¹

50
- 3142748255
- -4351
- C. M. Schultes B. Guyen J. Cuesta S. Neidle Bioorg. Med. Chem. Lett. 2004 14 4347 4351
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 4347
- Schultes, C.M.¹ Guyen, B.² Cuesta, J.³ Neidle, S.⁴

51
- 0037423728
- -125
- S. M. Haider G. N. Parkinson S. Neidle J. Mol. Biol. 2003 326 117 125
- (2003) J. Mol. Biol. , vol.326 , pp. 117
- Haider, S.M.¹ Parkinson, G.N.² Neidle, S.³

52
- 33847675742
- -2397
- G. N. Parkinson R. Ghosh S. Neidle Biochemistry 2007 46 2390 2397
- (2007) Biochemistry , vol.46 , pp. 2390
- Parkinson, G.N.¹ Ghosh, R.² Neidle, S.³

53
- 0034619427
- The mechanism of action of G-quadruplex ligands in the TRAP assay is more complex than previously assumed, see: -13432
- M. A. Read S. Neidle Biochemistry 2000 39 13422 13432
- (2000) Biochemistry , vol.39 , pp. 13422
- Read, M.A.¹ Neidle, S.²

54
- 36849081775
- -17352
- A. De Cian G. Cristofari P. Reichenbach E. De Lemos D. Monchaud M.-P. Teulade-Fichou K. Shin-ya L. Lacroix J. Lingner J.-L. Mergny Proc. Natl. Acad. Sci. U. S. A. 2007 104 17347 17352
- (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 17347
- De Cian, A.¹ Cristofari, G.² Reichenbach, P.³ De Lemos, E.⁴ Monchaud, D.⁵ Teulade-Fichou, M.-P.⁶ Shin-Ya, K.⁷ Lacroix, L.⁸ Lingner, J.⁹ Mergny, J.-L.¹⁰

55
- 49149147973
- -3228
- J. Gasteiger M. Marsili Tetrahedron 1980 36 3219 3228
- (1980) Tetrahedron , vol.36 , pp. 3219
- Gasteiger, J.¹ Marsili, M.²

56
- 11644261806
- -1662
- G. M. Morris D. S. Goodsell R. S. Halliday R. Huey W. E. Hart R. K. Belew A. J. Olsen J. Comput. Chem. 1998 19 1639 1662
- (1998) J. Comput. Chem. , vol.19 , pp. 1639
- Morris, G.M.¹ Goodsell, D.S.² Halliday, R.S.³ Huey, R.⁴ Hart, W.E.⁵ Belew, R.K.⁶ Olsen, A.J.⁷

57
- 0019525292
- -30
- F. J. Solis J. B. Wets Math. Oper. Res. 1981 6 19 30
- (1981) Math. Oper. Res. , vol.6 , pp. 19
- Solis, F.J.¹ Wets, J.B.²

58
- 0037763817
- -2303
- R. Wang Y. Lu S. Wang J. Med. Chem. 2003 46 2287 2303
- (2003) J. Med. Chem. , vol.46 , pp. 2287
- Wang, R.¹ Lu, Y.² Wang, S.³

59
- 20544433165
- -451
- A. Bondi J. Phys. Chem. 1964 68 441 451
- (1964) J. Phys. Chem. , vol.68 , pp. 441
- Bondi, A.¹

60
- 33646359481
- P. Hazel G. N. Parkinson S. Neidle Nucleic Acids Res. 2006 34 2117 2127
- (2006) Nucleic Acids Res. , vol.34 , pp. 2117-2127
- Hazel, P.¹ Parkinson, G.N.² Neidle, S.³

61
- 23444454552
- D. A. Case T. E. Cheatham 3rd T. Darden H. Gohlke R. Luo K. M. Merz, Jr A. Onufriev C. Simmerling B. Wang R. J. Woods J. Comput. Chem. 2005 26 1668 1688
- (2005) J. Comput. Chem. , vol.26 , pp. 1668-1688
- Case, D.A.¹ Cheatham III, T.E.² Darden, T.³ Gohlke, H.⁴ Luo, R.⁵ Merz Jr., K.M.⁶ Onufriev, A.⁷ Simmerling, C.⁸ Wang, B.⁹ Woods, R.J.¹⁰

62
- 10844247921
- -10103
- D. J. Price C. L. Brooks 3rd J. Chem. Phys. 2004 121 10096 10103
- (2004) J. Chem. Phys. , vol.121 , pp. 10096
- Price, D.J.¹ Brooks III, C.L.²

63
- 33646940952
- -341
- J.-P. Ryckaert G. Ciccotti H. J. C. Berendsen J. Comp. Phys. 1977 23 327 341
- (1977) J. Comp. Phys. , vol.23 , pp. 327
- Ryckaert, J.-P.¹ Ciccotti, G.² Berendsen, H.J.C.³

64
- 0023779259
- -18
- M. K. Gilson B. Honig Proteins: Struct., Funct., Genet. 1988 4 7 18
- (1988) Proteins: Struct., Funct., Genet. , vol.4 , pp. 7
- Gilson, M.K.¹ Honig, B.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.