Guggulsterone blocks IL-1β-mediated inflammatory responses by suppressing NF-κB activation in fibroblast-like synoviocytes

Life Sciences

Volumn 82, Issue 23-24, 2008, Pages 1203-1209

  Lee, Young Rae ^a   Lee, Ji Hyun ^a   Noh, Eun Mi ^a   Kim, Eun Kyung ^a   Song, Mi Young ^a   Jung, Won Seok ^b   Park, Sung Joo ^b   Kim, Jong Suk ^a   Park, Jin Woo ^a   Kwon, Kang Beom ^b   Park, Byung Hyun ^a  

^a Chonbuk National University   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

Fibroblast like synoviocytes; Guggulsterone; IL 1 ; MMP; NF B

Indexed keywords

CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GELATIN; GUGGULSTERONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; PROTEIN P50; RANTES; STROMELYSIN; SYNAPTOTAGMIN I;

ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL STIMULATION; CYTOKINE PRODUCTION; CYTOPLASM; DRUG EFFECT; ENZYME ACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; INFLAMMATION; PROTEIN BINDING; PROTEIN DEGRADATION; RHEUMATIC DISEASE; SYNOVIOCYTE; WESTERN BLOTTING; ZYMOGRAPHY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; CELLS, CULTURED; FIBROBLASTS; HUMANS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; NF-KAPPA B; PREGNENEDIONES; SYNOVIAL MEMBRANE;

EID: 43949085015     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.04.006     Document Type: Article

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