Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings through presynaptic sst2 receptors linked to the adenylyl cyclase-protein kinase a pathway

Neuropharmacology

Volumn 46, Issue 3, 2004, Pages 388-396

  Grilli, Massimo ^a   Raiteri, Luca ^a   Pittaluga, Anna ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Cyclic AMP; Glutamate release; Mouse cortex; Protein kinase A; sst2 Receptors; Superfused synaptosomes

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE ACTIVATOR; CYANAMID 154806; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DEXTRO ASPARTIC ACID; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; ENZYME INHIBITOR; FORSKOLIN; GLUTAMIC ACID; L 362855; L 779976; L 796778; L 797591; L 803087; N (2 PHENYLCYCLOPENTYL)AZACYCLOTRIDECAN 2 IMINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OCTREOTIDE; POTASSIUM ION; PRESYNAPTIC RECEPTOR; RECEPTOR BLOCKING AGENT; SOMATOSTATIN 14; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; DRUG SELECTIVITY; ENZYME INHIBITION; MALE; MOUSE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 1242306515     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2003.09.012     Document Type: Article

References (45)

1. Bell G.I., Reisine T. Molecular biology of somatostatin receptors. Trends Neurosci. 16:1995;34-38.
2. 1-subtype-selective nonpeptidyl agonist. Neuropharmacology. 40:2001;590-596.
3. Boehm S., Betz H. Somatostatin inhibits excitatory transmission at rat hippocampal synapse via presynaptic receptors. J. Neurosci. 17:1997;4066-4075.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
5. 2+ channels. Annu. Rev. Cell Dev. Biol. 16:2000;521-555.
6. Chavez-Noriega L.E., Stevens C.F. Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices. J. Neurosci. 14:1994;310-317.
7. Chijiwa T., Mishima A., Hagiwara M., Sano M., Hayashi K., Inoue T., Naito K., Toshioka T., Hidaka H. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino) ethyl]-5-isoquinoline sulfonamide (H-89), of PC12D pheochromocytoma cells. J. Biol. Chem. 265:1990;5267-5272.
8. Csaba Z., Dournaud P. Cellular biology of somatostatin receptors. Neuropeptides. 35:2001;1-23.
9. Dutar P., Vaillend C., Viollet C., Billard J.M., Potier B., Carlo A.S., Ungerer A., Epelbaum J. Spatial learning and synaptic hippocampal plasticity in type 2 somatostatin receptor knock-out mice. Neuroscience. 112:2002;455-466.
10. Epelbaum J., Dournaud P., Fodor M., Grenet C. The neurobiology of somatostatin. Crit. Rev. Neurobiol. 8:1994;25-44.
11. 2 (CYANAMID 154806). Br. J. Pharmacol. 123:1998;111P.
12. 2 receptor blockade with the novel cyclic octapeptide, CYN-154806. Neuropharmacology. 39:2000;1443-1450.
13. Greengard P. Neuroscience - The neurobiology of slow synaptic transmission. Science. 294:2001;1024-1030.
14. 1-5 receptor mRNA and binding in mouse brain by semi-quantitative RT-PCR, in situ hybridisation histochemistry and receptor autoradiography. Neuropharmacology. 42:2002;396-413.
15. Hathway G.J., Emson P.C., Humphrey P.P.A., Kendrick K.M. Somatostatin potently stimulates in vivo striatal dopamine and γ-aminobutyric acid release by a glutamate-dependent action. J. Neurochem. 70:1998;1740-1749.
16. Hoyer D., Lübbert H., Bruns C. Molecular pharmacology of somatostatin receptors. Naunyn Schmiedeberg's Arch. Pharmacol. 350:1994;441-453.
17. Hoyer D., Bell G.I., Berelowitz M., Feniuk W., Humphrey P.P.A., O'Carroll A.M., Patel Y.C. Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci. 16:1995;86-88.
18. Humphrey P.P.A., Epelbaum J., Feniuk W., Hoyer D., Taylor J.E., Reisine T.R. Classification of somatostatin receptors. The IUPHAR Compendium of Receptor Characterization and Classification. 1998;246-255 IUPHAR Media.
19. Lanneau C., Viollet C., Faivre-Bauman A., Loudes C., Kordon C., Epelbaum J., Gardette R. Somatostatin receptor subtypes sst1 and sst2 elicit opposite effects on the response to glutamate of mouse hypothalamic neurones: an electrophysiological and single cell RT-PCR study. Eur. J. Neurosci. 10:1998;204-212.
20. Lippe C., Ardizzone C. Actions of vasopressin and isoprenaline on the ionic transport across the isolated frog skin in the presence and the absence of adenyl cyclase inhibitors MDL12330A and SQ22536. Comp. Biochem. Physiol. C. 99:1991;209-211.
21. Marchi M., Raiteri L., Risso F., Vallarino A., Bonfanti A., Monopoli A., Ongini E., Raiteri M. Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes. Br. J. Pharmacol. 136:2002;434-440.
22. 1D receptors. Br. J. Pharmacol. 123:1998;45-50.
23. Moneta D., Richichi C., Aliprandi M., Dournaud P., Dutar P., Billard J.M., Carlo A.S., Viollet C., Hannon J.P., Fehlmann D., Nunn C., Hoyer D., Epelbaum J., Vezzani A. Somatostatin receptor subtypes 2 and 4 affect seizure susceptibility and hippocampal excitatory neurotransmission in mice. Eur. J. Neurosci. 16:2002;843-849.
24. Nakamura Y., Iga K., Shibata T., Shudo M., Kataoka K. Glial plasmalemmal vesicles: a subcellular fraction from rat hippocampal homogenate distinct from synaptosomes. Glia. 9:1993;48-56.
25. Paudice P., Gemignani A., Raiteri M. Evidence for functional native NMDA receptors activated by glycine or D-serine alone in the absence of glutamatergic coagonist. Eur. J. Neurosci. 10:1998;2934-2944.
26. Peineau S., Potier B., Petit F., Dournaud P., Epelbaum J., Gardette R. AMPA-sst2 somatostatin receptor interaction in rat hypothalamus requires activation of NMDA and/or metabotropic glutamate receptors and depends on intracellular calcium. J. Physiol. 546:(1):2003;101-117.
27. Pittaluga A., Vaccari D., Raiteri M. The "kynurenate test", a biochemical assay for putative cognition enhancers. J. Pharmacol. Exp. Ther. 283:1997;82-90.
28. 2+ block without depolarization. Br. J. Pharmacol. 130:2000;557-566.
29. Raiteri L., Raiteri M. Synaptosomes still viable after 25 years of superfusion. Neurochem. Res. 25:2000;1265-1274.
30. Raiteri M., Marchi M., Caviglia A.M. Studies on a possible functional coupling between presynaptic acetylcholinesterase and high-affinity choline uptake in the rat brain. J. Neurochem. 47:1986;1696-1699.
31. 2 'cardiac' muscarinic receptors. Eur. J. Pharmacol. 177:1990;181-187.
32. Rohrer S.P., Birzin E.T., Mosley R.T., Berk S.C., Hutchins S.M., Shen D.-M., Xiong Y., Hayes E.C., Parmar R.M., Foor F., Mitra S.W., Degrado S.J., Shu M., Klopp J.M., Cai S.-J., Blake A., Chan W.W.S., Pasternak A., Yang L., Patchett A.A., Smith R.G., Chapman K.T., Schaeffer J.M. Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science. 282:1998;737-740.
33. Rubinow D.R., Davis C.L., Post R.M. Somatostatin in the central nervous system. Bloom F.E., Kupfer D.J. Psychopharmacology: The Fourth Generation of Progress. 1995;553-596 Raven Press, New York.
34. Schettini G. Brain somatostatin: receptor-coupled transducing mechanisms and role in cognitive functions. Pharmacol. Res. 23:1991;203-215.
35. Schoepp D.D. Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J. Pharmacol. Exp. Ther. 299:2001;12-20.
36. Sequeira S.M., Malva J.O., Carvalho A.P., Carvalho C.M. Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals. Mol. Brain Res. 89:2001;111-118.
37. Siehler S., Hoyer D. Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity. Naunyn-Schmiedeberg's Archives of Pharmacology. 360:1999;522-532.
38. Siehler S., Seuwen K., Hoyer D. Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies. Naunyn-Schmiedeberg's Archives of Pharmacology. 360:1999;488-499.
39. Tallent M.K., Siggins G.R. Somatostatin depresses excitatory but not inhibitory neurotransmission in rat CA1 hippocampus. J. Neurophysiol. 78:1997;3008-3018.
40. Tapia-Arancibia L., Astier H. Actions of excitatory amino acids on somatostatin release from cortical neurons in primary cultures. J. Neurochem. 53:1989;1134-1141.
41. Trudeau L.E., Emery D.G., Haydon P.G. Direct modulation of the secretory machinery underlies PKA-dependent synaptic facilitation in hippocampal neurons. Neuron. 17:1996;789-797.
42. Vezzani A., Rizzi M., Conti M., Samanin R. Glutamate and glutamine in the brain. J. Nutr. 130:2000;1046S-1048S.
43. Wang S.J., Sihra T.S. Opposing facilitatory and inhibitory modulation of glutamate release elicited by cAMP production in cerebrocortical nerve terminals (synaptosomes). Neuropharmacology. 44:2003;686-697.
44. Wang H.B., Storm D.R. Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system. Mol. Pharmacol. 63:2003;463-468.
45. 5 receptors mediating activation of phosphoinositide metabolism. Br. J. Pharmacol. 121:1997;91-96.