Mutations at arginine 352 alter the pore architecture of CFTR

Journal of Membrane Biology

Volumn 222, Issue 2, 2008, Pages 91-106

  Cui, Guiying ^a,b   Zhang, Zhi Ren ^a   O'Brien, Andrew R W ^a   Song, Binlin ^a   McCarty, Nael A ^a,b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anion selectivity; Blocker; CFTR; Channel open state; Chloride channel; Salt bridge; Subconductance

Indexed keywords

ANION; ARGININE; GLIPIZIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARCHITECTURE; ARTICLE; GENE MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; CYSTEINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DRUG STABILITY; ELECTROPHYSIOLOGY; ETHYL METHANESULFONATE; FEMALE; GLIPIZIDE; HUMANS; ION CHANNEL GATING; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 43549091314     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-008-9105-9     Document Type: Article

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