Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels

Journal of General Physiology

Volumn 110, Issue 4, 1997, Pages 341-354

  Tabcharani, Joseph A ^a   Linsdell, Paul ^a   Hanrahan, John W ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Iodide permeability; Lyotropic sequence

Indexed keywords

CHLORIDE CHANNEL; CHLORIDE ION; HALIDE; IODIDE ION; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CHLORIDE CONDUCTANCE; CHO CELL; CONTROLLED STUDY; NONHUMAN;

ANIMALS; CHO CELLS; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HALOGENS; ION CHANNEL GATING; ION CHANNELS; SOLUTIONS; THIOCYANATES;

EID: 0030964656     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.110.4.341     Document Type: Article

References (64)

1. Anderson, M.P., R.J. Gregory, S. Thompson, D.W. Souza, S. Paul, R.C. Mulligan, A.E. Smith, and M.J. Welsh. 1991. Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (Wash. DC). 253:202-205.
2. Anderson, M.P., and M.J. Welsh. 1991. Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc. Natl. Acad. Sci. USA. 88:6003-6007.
3. Bajnath, R.B., J.A. Groot, H.R. De Jonge, M. Kansen, and J. Bijman. 1993. Synergistic activation of non-rectifying small-conductance chloride channels by forskolin and phorbol esters in cell-attached patches of the human colon carcinoma cell line HT-29cl.19A. Pflügers Arch. 425:100-108.
4. - channel activity in Xenopus oocytes expressing the cystic fibrosis gene. J. Biol. Chem. 266:19142-19145.
5. Bear, C.E., C. Li, N. Kartner, R.J. Bridges, T.J. Jensen, M. Ramjeesingh, and J.R. Riordan. 1992. Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell. 68:809-818.
6. Bear, C.E., and E.F. Reyes. 1992. cAMP-activated chloride conductance in the colonic cell line, Caco-2. Am. J. Physiol. 262:C251-C256.
7. Becq, F., T.J. Jensen, X.-B. Chang, A. Savoia, J.M. Rommens, L.-C. Tsui, M. Buchwald, J.R. Riordan, and J.W. Hanrahan. 1994. Phosphatase inhibitors activate normal and defective CFTR chloride channels. Proc. Natl. Acad. Sci. USA. 91:9160-9164.
8. - conductance affected in cystic fibrosis. Am. J. Physiol. 262:C555-C562.
9. Berger, H.A., M.P. Anderson, R.J. Gregory, S. Thompson, P.W. Howard, R.A. Maurer, R. Mulligan, A.E. Smith, and M.J. Welsh. 1991. Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. J. Clin. Invest. 88:1422-1431.
10. - channels. Biophys. J. 67:1867-1875.
11. Champigny, G., B. Verrier, C. Gérard, J. Mauchamp, and M. Lazdunski. 1990. Small conductance chloride channels in the apical membrane of thyroid cells. FEBS Lett. 259:263-268.
12. Chan, H.-C., J. Goldstein, and D.J. Nelson. 1992. Alternate pathways for chloride conductance activation in normal and cystic fibrosis airway epithelial cells. Am. J. Physiol. 262:C1273-C1283.
13. Chang, X.-B., J.A. Tabcharani, Y.-X. Hou, T.J. Jensen, N. Kartner, N. Alon, J.W. Hanrahan, and J.R. Riordan. 1993. Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all ten PKA consensus phosphorylation sites. J. Biol. Chem. 268: 11304-11311.
14. Cheung, M., and M.H. Akabas. 1997. Locating the anion selectivity filter of the CFTR chloride channel. J. Gen. Physiol. 109:289-299.
15. Cheung, M., and M.H. Akabas. 1996. Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment. Biophys. J. 70:2688-2695.
16. Cliff, W.H., R.A. Schoumacher, and R.A. Frizzell. 1992. cAMP-activated Cl channels in CFTR-transfected CF pancreatic epithelial cells. Am. J. Physiol. 262:C1154-1160.
17. - secreting epithelial cells. Proc. Natl. Acad. Sci. USA. 87:4956-4960.
18. Collins, K.D., and M.W. Washabaugh. 1985. The Hofmeister effect and the behaviour of water at interfaces. Q. Rev. Biophys. 18:323-422.
19. Cornette, J.L., K.B. Cease, H. Margalit, J.L. Sponge, J.A. Berzofsky, and C. DeLisi. 1987. Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins. J. Mol. Biol. 195:659-685.
20. Dani, J.A., J.A. Sanchez, and B. Hille. 1983. Lyotropic anions. Na channel gating and Ca electrode response. J. Gen. Physiol. 81: 255-281.
21. Dousmanis, A.G., and D.C. Gadsby. 1994. Anion permeability sequence of the open cardiac CFTR Cl channel. Biophys. J. 66:A421. (Abstr.)
22. Eisenman, G. 1962. Cation selective glass electrodes and their mode of operation. Biophys. J. 2(part 2 Suppl.):259-323.
23. Finkelstein, A., and A. Cass. 1968. Permeability and electrical properties of thin lipid membranes. J. Gen. Physiol. 52:145-173.
24. Fischer, H., and T.E. Machen. 1994. CFTR displays voltage dependence and two gating modes during stimulation. J. Gen. Physiol. 104:541-566.
25. Franciolini, F., and W. Nonner. 1994. Anion-cation interactions in the pore of neuronal background chloride channels. J. Gen. Physiol. 104:711-723.
26. Friel, D.D., and R.W. Tsien. 1989. Voltage-gated calcium channels: direct observation of the anomalous mole fraction effect at the single-channel level. Proc. Natl. Acad. Sci. USA. 86:5207-5211.
27. Gray, M.A., J.R. Greenwell, and B.E. Argent. 1988. Secretin-regulated chloride channel on the apical plasma membrane of pancreatic duct cells. J. Membr. Biol. 105:131-142.
28. Gray, M.A., A. Harris, L. Coleman, J.R. Greenwell, and B.E. Argent. 1989. Two types of chloride channel on duct cells cultured from human fetal pancreas. Am. J. Physiol. 257:C240-C251.
29. Gray, M.A., C.E. Pollard, A. Harris, L. Coleman, J.R. Greenwell, and B.E. Argent. 1990. Anion selectivity and block of the small conductance chloride channel on pancreatic duct cells. Am. J. Physiol. 259:C752-C761.
30. Hamabata, A., and P.H. Von Hippel. 1973. Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. II. Biochemistry. 12:1264-1282.
31. Hanrahan, J.W., and J.A. Tabcharani. 1990. Inhibition of an outwardly rectifying anion channel by HEPES and related buffers. J. Membr. Biol. 116:65-77.
32. Haws, C., M.E. Krouse, Y. Xia, D.C. Gruenert, and J.J. Wine. 1992. CFTR channels in immortalized human airway cells. Am. J. Physiol. 263:L692-L707.
33. Hofmeister, F. 1888. Zur Lehre von der Wirkung der Salze. Zweite Mittheilung. Ueber Regelmässig keiten in der eiwass fällenden Wirkung der Salze und ihre Besiehung zum physiologischen Verhalten derselben. Arch. Exp. Pathol. Pharmakol. 24:247-260.
34. Kartner, N., J.W. Hanrahan, T.J. Jensen, A.L. Naismith, S. Sun, C.A. Ackerley, E.F. Reyes, L. Tsui, J.M. Rommens, C.E. Bear, and J.R. Riordan. 1991. Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance. Cell. 64:681-691.
35. - conductance in the apical membrane of Necturus gallbladder epithelium. Pflügers Arch. 429:647-658.
36. Läuger, P., W. Lesslauer, E. Marti, and J. Richter. 1967. Electrical properties of bimolecular phospholipid membranes. Biochim. Biophys. Acta. 135:20-32.
37. Linsdell, P., J.A. Tabcharani, and J.W. Hanrahan. 1997a. A multi-ion mechanism for ion permeation and block in the CFTR chloride channel. J. Gen. Physiol. 110:365-377.
38. Linsdell, P., J.A. Tabcharani, J.M. Rommens, Y.-X. Hou, X.-B. Chang, L.-C. Tsui, J.R. Riordan, and J.W. Hanrahan. 1997b. Permeability of wild-type and mutant CFTR chloride channels to polyatomic anions. J. Gen. Physiol. 110:355-364.
39. - channels expressed in a mammalian cell line and its regulation by a critical pore residue. J. Physiol. (Cambr.) 496:687-693.
40. Linsdell, P., and J.W. Hanrahan. 1996b. Flickery block of single CFTR chloride channels by intracellular anions and osmolytes. Am. J. Physiol. 271:C628-C634.
41. McDonough, S., N. Davidson, H.A. Lester, and N.A. McCarty. 1994. Novel pore-lining residues in CFTR that govern permeation and open-channel block. Neuron. 13:623-634.
42. McLaughlin, S., A. Bruder, S. Chen, and C. Moser. 1975. Chaotropic anions and the surface potential of bilayer membranes. Biochim. Biophys. Acta. 394:304-313.
43. Neher, E. 1992. Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol. 27:123-131.
44. Overholt, J.L., M.E. Hobert, and R.D. Harvey. 1993. On the mechanism of rectification of the isoproterenol-activated chloride current in Guinea-pig ventricular myocytes. J. Gen. Physiol. 102:871-895.
45. Riordan, J.R., B. Forbush III, and J.W. Hanrahan. 1994. The molecular basis of chloride transport in shark rectal gland. J. Exp. Biol. 196:405-418.
46. Robinson, D.R., and W.P. Jencks. 1965. The effect of compounds of the urea-guanidinium class on the activity coeficient of acetyl-tetraglycine ethyl ester and related compounds. J. Am. Chem. Soc. 87: 2462-2470.
47. Robinson, R.A., and R.H. Stokes. 1970. Electrolyte solutions. 2nd revised ed. Butterworth-Heinemann Ltd., London.
48. Rommens, J.M., S. Dho, C.E. Bear, N. Kartner, D. Kennedy, J.R. Riordan, L. Tsui, and K. Foskett. 1991. cAMP-inducible chloride conductance in mouse fibroblast lines stably expressing human cystic fibrosis transmembrane conductance regulator. Proc. Natl. Acad. Sci. USA. 88:7500-7504.
49. - conductances in fused human respiratory epithelial cells II. Relation to cystic fibrosis gene product. Pflügers Arch. 430: 257-264.
50. Seibert, F.S., P. Linsdell, T.W. Loo, J.W. Hanrahan, D.M. Clarke, and J.R. Riordan. 1996. Disease-associated mutations in the fourth cytoplasmic loop of cystic fibrosis transmembrane conductance regulator compromise biosynthetic processing and chloride channel activity. J. Biol. Chem. 271:15139-15145.
51. - channels with altered pore properties. Nature (Lond.). 362:160-164.
52. Sheppard, D.N., L.S. Ostedgaard, M.C. Winter, and M.J. Welsh. 1995. Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency. EMBO (Eur. Mol. Biol. Organ.) J. 14:876-883.
53. Tabcharani, J.A., T.J. Jensen, J.R. Riordan, and J.W. Hanrahan. 1989. Bicarbonate permeability of the outwardly rectifying anion channel. J. Membr. Biol. 112:109-122.
54. 84. FEBS Lett. 270:157-164.
55. - channel in CHO cells stably expressing the cystic fibrosis gene. Nature (Lond.). 352:628-631.
56. Tabcharani, J.A., X.-B. Chang, J.R. Riordan, and J.W. Hanrahan. 1992. The cystic fibrosis transmembrane conductance regulator chloride channel: iodide block and permeation. Biophys. J. 62:1-4.
57. Tabcharani, J.A., J.M. Rommens, Y.-X. Hou, X.-B. Chang, L.-C. Tsui, J.R. Riordan, and J.W. Hanrahan. 1993. Multi-ion pore behaviour in the CFTR chloride channel. Nature (Lond.). 366:79-82.
58. Tabcharani, J.A., and J.W. Hanrahan. 1993. Permeation in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. Biophys. J. 64:A17. (Abstr.)
59. Tessman, J.R., A.H. Kahn, and W. Shockley. 1953. Electronic polarizabilities of ions in crystals. Phys. Rev. 92:890-895.
60. Venglarik, C.J., B.D. Schultz, R.A. Frizzell, and R.J. Bridges. 1994. ATP alters current fluctuations of cystic fibrosis transmembrane conductance regulator: evidence for a three state activation mechanism. J Gen. Physiol. 104:123-146.
61. Walsh, K.B., and K.J. Long. 1992. Inhibition of heart calcium and chloride currents by sodium iodide. J. Gen. Physiol. 100:847-865.
62. Welsh, M.J., P.L. Smith, and R.A. Frizzell. 1982. Chloride secretion by canine tracheal epithelium. II. The cellular electrical potential profile. J. Membr. Biol. 70:227-238.
63. Wolfenden, R., L. Andersson, P.M. Cullis, and C.C. Southgate. 1981. Affinities of amino acid side chains for solvent water. Biochemistry. 20:849-855.
64. Wright, E.M., and J.M. Diamond. 1977. Anion selectivity in biological systems. Physiol. Rev. 57:109-157.