Steady-state interactions of glibenclamide with CFTR: Evidence for multiple sites in the pore

Journal of Membrane Biology

Volumn 199, Issue 1, 2004, Pages 15-28

  Zhang, Z R ^a   Zeltwanger, S ^a   McCarty, N A ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chloride channel; Cystic fibrosis transmembrane conductance regulator; Open channel blocker; Permeation; Sulfonylurea

Indexed keywords

BUFFER; GLIBENCLAMIDE; SULFONYLUREA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOPLASM; DRUG BINDING; DRUG MECHANISM; KINETICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; OOCYTE; STEADY STATE; XENOPUS;

ANIMALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FEMALE; GLYBURIDE; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; XENOPUS;

ANIMALIA;

EID: 2942659790     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-004-0672-0     Document Type: Article

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