-
1
-
-
0036114263
-
Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma
-
M. M. Fitzek, W. K. Dahlberg, H. Nagasawa, S. Mukai, J. E. Munzenrider and J. B. Little, Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma. Int. J. Cancer 99, 764-768 (2002).
-
(2002)
Int. J. Cancer
, vol.99
, pp. 764-768
-
-
Fitzek, M.M.1
Dahlberg, W.K.2
Nagasawa, H.3
Mukai, S.4
Munzenrider, J.E.5
Little, J.B.6
-
2
-
-
33645727621
-
Abnormal gene expression profiles in unaffected parents of patients with hereditary type retinoblastoma
-
E. Y. Chuang, X. Chen, M-H. Tsai, H. Yan, C-Y. Li, J. B. Mitchell, H. Nagasawa, P. F. Wilson, Y. Peng and J. B. Little, Abnormal gene expression profiles in unaffected parents of patients with hereditary type retinoblastoma. Cancer Res. 66, 3428-3433 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 3428-3433
-
-
Chuang, E.Y.1
Chen, X.2
Tsai, M.-H.3
Yan, H.4
Li, C.-Y.5
Mitchell, J.B.6
Nagasawa, H.7
Wilson, P.F.8
Peng, Y.9
Little, J.B.10
-
3
-
-
3242876404
-
Ataxia-telangiectasia, an evolving phenotype
-
H. H. Chun and R. A. Gatti, Ataxia-telangiectasia, an evolving phenotype. DNA Repair 3, 1187-1196 (2004).
-
(2004)
DNA Repair
, vol.3
, pp. 1187-1196
-
-
Chun, H.H.1
Gatti, R.A.2
-
4
-
-
3242889151
-
Ataxia-telangiectasia-like disorder (ATLD) - its clinical presentation and molecular basis
-
A. M. R. Taylor, A. Groom and P. J. Byrd. Ataxia-telangiectasia-like disorder (ATLD) - its clinical presentation and molecular basis. DNA Repair 3, 1219-1225 (2004).
-
(2004)
DNA Repair
, vol.3
, pp. 1219-1225
-
-
Taylor, A.M.R.1
Groom, A.2
Byrd, P.J.3
-
5
-
-
3242892589
-
Nijmegen breakage syndrome: Clinical manifestation of defective response to DNA double-strand breaks
-
M. Digweed and K. Sperling, Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair 3, 1207-1217 (2004).
-
(2004)
DNA Repair
, vol.3
, pp. 1207-1217
-
-
Digweed, M.1
Sperling, K.2
-
7
-
-
0027473181
-
Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: A comprehensive survey of genetic and biochemical characteristics
-
A. R. Collins, Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res. DNA Repair 293, 99-118 (1993).
-
(1993)
Mutat. Res. DNA Repair
, vol.293
, pp. 99-118
-
-
Collins, A.R.1
-
8
-
-
20644450114
-
Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells
-
J. M. Hinz, N. A. Yamada, E. P. Salazar, R. S. Tebbs and L. H. Thompson, Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells. DNA Repair 4, 782-792 (2005).
-
(2005)
DNA Repair
, vol.4
, pp. 782-792
-
-
Hinz, J.M.1
Yamada, N.A.2
Salazar, E.P.3
Tebbs, R.S.4
Thompson, L.H.5
-
9
-
-
0025330351
-
Radiosensitivity of skin fibroblasts from atomic bomb survivors with and without breast cancer
-
S. Ban, R. B. Setlow, M. A. Bender, H. Ezaki, T. Hiraoka, M. Yamane, M. Nishiki, K. Dohi, A. A. Awa and G. W. Beebe, Radiosensitivity of skin fibroblasts from atomic bomb survivors with and without breast cancer. Cancer Res. 50, 4050-4055 (1990).
-
(1990)
Cancer Res
, vol.50
, pp. 4050-4055
-
-
Ban, S.1
Setlow, R.B.2
Bender, M.A.3
Ezaki, H.4
Hiraoka, T.5
Yamane, M.6
Nishiki, M.7
Dohi, K.8
Awa, A.A.9
Beebe, G.W.10
-
10
-
-
0035328461
-
Evidence of DNA repair/processing defects in cultured skin fibroblasts from breast cancer patients
-
M. A. Hannan, Y. Siddiqui, A. Rostom, M. N. Al-Ahdal, M. A. Chaudhary and M. Kunhi, Evidence of DNA repair/processing defects in cultured skin fibroblasts from breast cancer patients. Cancer Res. 61, 3627-3631 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 3627-3631
-
-
Hannan, M.A.1
Siddiqui, Y.2
Rostom, A.3
Al-Ahdal, M.N.4
Chaudhary, M.A.5
Kunhi, M.6
-
11
-
-
2642525186
-
Chromosomal radiosensitivity and low penetrance predisposition to cancer
-
D. Scott, Chromosomal radiosensitivity and low penetrance predisposition to cancer. Cytogenet. Genome Res. 104, 365-370 (2004).
-
(2004)
Cytogenet. Genome Res
, vol.104
, pp. 365-370
-
-
Scott, D.1
-
12
-
-
0018653177
-
G2 chromosomal radiosensitivity in Fanconi's anemia
-
S. B. Bigelow, J. M. Rary and M. A. Bender, G2 chromosomal radiosensitivity in Fanconi's anemia. Mutat. Res. 63, 189-199 (1979).
-
(1979)
Mutat. Res
, vol.63
, pp. 189-199
-
-
Bigelow, S.B.1
Rary, J.M.2
Bender, M.A.3
-
13
-
-
2442658200
-
Lack of sensitivity of primary Fanconi's anemia fibroblasts to UV and ionizing radiation
-
R. Kalb, M. Duerr, M. Wagner, S. Herterich, M. Gross, M. Digweed, H. Joenje, H. Hoehn and D. Schindler, Lack of sensitivity of primary Fanconi's anemia fibroblasts to UV and ionizing radiation. Radiat. Res. 161, 318-325 (2004).
-
(2004)
Radiat. Res
, vol.161
, pp. 318-325
-
-
Kalb, R.1
Duerr, M.2
Wagner, M.3
Herterich, S.4
Gross, M.5
Digweed, M.6
Joenje, H.7
Hoehn, H.8
Schindler, D.9
-
14
-
-
0018890926
-
X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders
-
R. R. Weichselbaum, J. Nove and J. B. Little, X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders. Cancer Res. 40, 920-925 (1980).
-
(1980)
Cancer Res
, vol.40
, pp. 920-925
-
-
Weichselbaum, R.R.1
Nove, J.2
Little, J.B.3
-
15
-
-
0020587099
-
Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts
-
H. Nagasawa and J. B. Little, Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts. Mutat. Res. 109, 297-308 (1983).
-
(1983)
Mutat. Res
, vol.109
, pp. 297-308
-
-
Nagasawa, H.1
Little, J.B.2
-
16
-
-
0023223245
-
X-radiation-induced chromosome breakage in retinoblastoma lymphocytes
-
J. G. Heras and R. Coco, X-radiation-induced chromosome breakage in retinoblastoma lymphocytes. Mutat. Res. 178, 225-233 (1987).
-
(1987)
Mutat. Res
, vol.178
, pp. 225-233
-
-
Heras, J.G.1
Coco, R.2
-
17
-
-
0023176338
-
X-ray sensitivity of fibroblasts from patients with hereditary retinoblastoma and their families
-
J. V. Pledger, A. W. Craft, K. Bartlett and D. R. Long, X-ray sensitivity of fibroblasts from patients with hereditary retinoblastoma and their families. Br. J. Cancer 55, 617-621 (1987).
-
(1987)
Br. J. Cancer
, vol.55
, pp. 617-621
-
-
Pledger, J.V.1
Craft, A.W.2
Bartlett, K.3
Long, D.R.4
-
18
-
-
0024309898
-
Radiation sensitivity of cell strains from families with genetic disorders predisposing to radiation-induced cancer
-
J. B. Little, W. W. Nichols, P. Troilo, H. Nagasawa and L. C. Strong, Radiation sensitivity of cell strains from families with genetic disorders predisposing to radiation-induced cancer. Cancer Res. 49, 4705-4714 (1989).
-
(1989)
Cancer Res
, vol.49
, pp. 4705-4714
-
-
Little, J.B.1
Nichols, W.W.2
Troilo, P.3
Nagasawa, H.4
Strong, L.C.5
-
19
-
-
0025345637
-
Sensitivity of human diploid fibroblast cell strains from various genetics disorders to acute and protracted radiation exposure
-
J. B. Little and J. Nove, Sensitivity of human diploid fibroblast cell strains from various genetics disorders to acute and protracted radiation exposure. Radiat. Res. 123, 87-92 (1990).
-
(1990)
Radiat. Res
, vol.123
, pp. 87-92
-
-
Little, J.B.1
Nove, J.2
-
20
-
-
0027064986
-
Effect of dose rate on the survival of irradiated skin fibroblasts
-
H. Nagasawa, J. B. Little, N. M. Tsang, E. Saunders, J. Tesmer and G. F. Strniste, Effect of dose rate on the survival of irradiated skin fibroblasts. Radiat. Res. 132, 375-379 (1992).
-
(1992)
Radiat. Res
, vol.132
, pp. 375-379
-
-
Nagasawa, H.1
Little, J.B.2
Tsang, N.M.3
Saunders, E.4
Tesmer, J.5
Strniste, G.F.6
-
23
-
-
0026448469
-
Intrinsic radiosensitivity of normal fibroblasts and lymphocytes after high and low dose-rate irradiation
-
F. B. Geara, L. J. Peters, K. K. Ang, J. L. Wike, S. S. Sivon, R. Guttenberger, D. L. Callender, E. P. Malaise and W. A. Brock, Intrinsic radiosensitivity of normal fibroblasts and lymphocytes after high and low dose-rate irradiation. Cancer Res. 52, 6348-6352 (1992).
-
(1992)
Cancer Res
, vol.52
, pp. 6348-6352
-
-
Geara, F.B.1
Peters, L.J.2
Ang, K.K.3
Wike, J.L.4
Sivon, S.S.5
Guttenberger, R.6
Callender, D.L.7
Malaise, E.P.8
Brock, W.A.9
-
24
-
-
0018837288
-
Survey of radiosensitivity in a variety of human cell strains
-
C. F. Arlett and S. A. Harcourt, Survey of radiosensitivity in a variety of human cell strains. Cancer Res. 40, 926-932 (1980).
-
(1980)
Cancer Res
, vol.40
, pp. 926-932
-
-
Arlett, C.F.1
Harcourt, S.A.2
-
25
-
-
0023766336
-
2-phase chromosomal aberrations and cell cycle delay
-
2-phase chromosomal aberrations and cell cycle delay. Cancer Res. 48, 4535-4538 (1988).
-
(1988)
Cancer Res
, vol.48
, pp. 4535-4538
-
-
Nagasawa, H.1
Little, J.B.2
-
27
-
-
0242268054
-
Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts
-
E. Dikomey, K. Borgmann, I. Brammer and U. Kasten-Pisula, Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts. Toxicology 198, 125-135 (2003).
-
(2003)
Toxicology
, vol.198
, pp. 125-135
-
-
Dikomey, E.1
Borgmann, K.2
Brammer, I.3
Kasten-Pisula, U.4
-
28
-
-
0242501504
-
Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes
-
H. W. Mohrenweiser, D. M. Wilson, III and I. M. Jones, Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat. Res. 526, 93-125 (2003).
-
(2003)
Mutat. Res
, vol.526
, pp. 93-125
-
-
Mohrenweiser, H.W.1
Wilson III, D.M.2
Jones, I.M.3
-
29
-
-
2642527702
-
Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
-
T. Xi, I. M. Jones and H. W. Mohrenweiser, Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function. Genomics 83, 970-979 (2004).
-
(2004)
Genomics
, vol.83
, pp. 970-979
-
-
Xi, T.1
Jones, I.M.2
Mohrenweiser, H.W.3
-
30
-
-
3242876403
-
Genetic biomarkers of therapeutic radiation sensitivity
-
M. Fernet and J. Hall, Genetic biomarkers of therapeutic radiation sensitivity. DNA Repair 3, 1237-1243 (2004).
-
(2004)
DNA Repair
, vol.3
, pp. 1237-1243
-
-
Fernet, M.1
Hall, J.2
-
31
-
-
26444479826
-
Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk
-
R. C. Millikan, J. S. Player, A. R. de Cotret, C-K. Tse and T. Keku, Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 14, 2326-2334 (2005).
-
(2005)
Cancer Epidemiol. Biomarkers Prev
, vol.14
, pp. 2326-2334
-
-
Millikan, R.C.1
Player, J.S.2
de Cotret, A.R.3
Tse, C.-K.4
Keku, T.5
-
32
-
-
27844576828
-
Huge differences in cellular radiosensitivity due to only very small variations in doublestrand break repair capacity
-
U. Kasten-Pisula, H. Tastan and E. Dikomey, Huge differences in cellular radiosensitivity due to only very small variations in doublestrand break repair capacity. Int. J. Radiat. Biol. 81, 409-419 (2005).
-
(2005)
Int. J. Radiat. Biol
, vol.81
, pp. 409-419
-
-
Kasten-Pisula, U.1
Tastan, H.2
Dikomey, E.3
-
33
-
-
0036669735
-
Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look or it?
-
C. N. Andreassen, J. Alsner and J. Overgaard, Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look or it? Radiother. Oncol. 64, 131-140 (2002).
-
(2002)
Radiother. Oncol
, vol.64
, pp. 131-140
-
-
Andreassen, C.N.1
Alsner, J.2
Overgaard, J.3
-
34
-
-
0029840089
-
Low dose-rate fibroblast radiosensitivity and the prediction of patient response to radiotherapy
-
N. G. Burnet, R. Wurm and J. H. Peacock, Low dose-rate fibroblast radiosensitivity and the prediction of patient response to radiotherapy. Int. J. Radiat. Biol. 70, 289-300 (1996).
-
(1996)
Int. J. Radiat. Biol
, vol.70
, pp. 289-300
-
-
Burnet, N.G.1
Wurm, R.2
Peacock, J.H.3
-
35
-
-
0018642114
-
Genetics of retinoblastoma
-
F. Vogel, Genetics of retinoblastoma. Hum. Genet. 52, 1-54 (1979).
-
(1979)
Hum. Genet
, vol.52
, pp. 1-54
-
-
Vogel, F.1
-
36
-
-
0027172571
-
-
C. Eng, F. P. Li, D. H. Abramson, R. M. Ellsworth, F. L. Wong, M. B. Goldman, J. Seddon, N. Tarbell and J. D. Boice, Jr., Mortality from second tumors among long-term survivors of retinoblastoma. J. Natl. Cancer Inst. 85, 1121-1128 (1993).
-
C. Eng, F. P. Li, D. H. Abramson, R. M. Ellsworth, F. L. Wong, M. B. Goldman, J. Seddon, N. Tarbell and J. D. Boice, Jr., Mortality from second tumors among long-term survivors of retinoblastoma. J. Natl. Cancer Inst. 85, 1121-1128 (1993).
-
-
-
-
37
-
-
0030848527
-
Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk
-
F. L. Wong, J. D. Boice, Jr., D. H. Abramson, R. E. Tarone, R. A. Kleinerman, M. Stovall, M. B. Goldman, J. M. Seddon, N. Tarbell and F. P. Li, Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. J. Am. Med. Assoc. 278, 1262-1267 (1997).
-
(1997)
J. Am. Med. Assoc
, vol.278
, pp. 1262-1267
-
-
Wong, F.L.1
Boice Jr., J.D.2
Abramson, D.H.3
Tarone, R.E.4
Kleinerman, R.A.5
Stovall, M.6
Goldman, M.B.7
Seddon, J.M.8
Tarbell, N.9
Li, F.P.10
-
38
-
-
17144398035
-
-
R. A. Kleinerman, M. A. Tucker, R. E. Tarone, D. H. Abramson, J. M. Seddon, M. Stovall, F. P. Li and J. F. Fraumeni, Jr., Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J. Clin. Oncol. 23, 2272-2279 (2005).
-
R. A. Kleinerman, M. A. Tucker, R. E. Tarone, D. H. Abramson, J. M. Seddon, M. Stovall, F. P. Li and J. F. Fraumeni, Jr., Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J. Clin. Oncol. 23, 2272-2279 (2005).
-
-
-
-
39
-
-
18244365152
-
Genome instability in secondary tumors developing after radiotherapy of bilateral retinoblastoma
-
S. H. Lefèvre, N. Vogt, A-M. Dutrillaux, L. Chauveinc, D. Stoppa-Lyonnet, F. Doz, L. Desjardins, B. Dutrillaux, S. Chevillard and B. Malfoy, Genome instability in secondary tumors developing after radiotherapy of bilateral retinoblastoma. Oncogene 20, 8092-8099 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 8092-8099
-
-
Lefèvre, S.H.1
Vogt, N.2
Dutrillaux, A.-M.3
Chauveinc, L.4
Stoppa-Lyonnet, D.5
Doz, F.6
Desjardins, L.7
Dutrillaux, B.8
Chevillard, S.9
Malfoy, B.10
-
40
-
-
0037251401
-
Comparative genomic hybridization divides retinoblastomas into a high and a low-level chromosomal instability group
-
J. E. van der Wal, M. A. J. A. Hermsen, H. J. P. Gille, N. Y. N. Schouten-van Meeteren, A. C. Moll, S. M. Imhof, G. A. Meijer, J. P. A. Baak and P. van der Valk, Comparative genomic hybridization divides retinoblastomas into a high and a low-level chromosomal instability group. J. Clin. Pathol. 56, 26-30 (2003).
-
(2003)
J. Clin. Pathol
, vol.56
, pp. 26-30
-
-
van der Wal, J.E.1
Hermsen, M.A.J.A.2
Gille, H.J.P.3
Schouten-van Meeteren, N.Y.N.4
Moll, A.C.5
Imhof, S.M.6
Meijer, G.A.7
Baak, J.P.A.8
van der Valk, P.9
-
41
-
-
1642352674
-
Constitutional genomic instability, chromosome aberrations in tumor cells and retinoblastoma
-
P. S. Amare Kadam, P. Ghule, J. Jose, M. Bamne, P. Kurkure, S. Banavali, R. Sarin and S. Advani, Constitutional genomic instability, chromosome aberrations in tumor cells and retinoblastoma. Cancer Genet. Cytogenet. 150, 33-43 (2004).
-
(2004)
Cancer Genet. Cytogenet
, vol.150
, pp. 33-43
-
-
Amare Kadam, P.S.1
Ghule, P.2
Jose, J.3
Bamne, M.4
Kurkure, P.5
Banavali, S.6
Sarin, R.7
Advani, S.8
-
42
-
-
0036386059
-
Retinoblastoma tumor suppressor and genome stability
-
L. Zheng and W-H. Lee, Retinoblastoma tumor suppressor and genome stability. Adv. Cancer Res. 85, 13-50 (2002).
-
(2002)
Adv. Cancer Res
, vol.85
, pp. 13-50
-
-
Zheng, L.1
Lee, W.-H.2
-
43
-
-
0036569924
-
Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability
-
L. Zheng, A. Flesken-Nikitin, P-L. Chen and W-H. Lee, Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability. Cancer Res. 62, 2498-2502 (2002).
-
(2002)
Cancer Res
, vol.62
, pp. 2498-2502
-
-
Zheng, L.1
Flesken-Nikitin, A.2
Chen, P.-L.3
Lee, W.-H.4
-
44
-
-
4043093341
-
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
-
E. Hernando, Z. Nahlé, G. Juan, E. Diaz-Rodriguez, M. Alaminos, M. Hemann, L. Michel, V. Mittal, W. Gerald and C. Cordon-Cardo, Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature 430, 797-802 (2004).
-
(2004)
Nature
, vol.430
, pp. 797-802
-
-
Hernando, E.1
Nahlé, Z.2
Juan, G.3
Diaz-Rodriguez, E.4
Alaminos, M.5
Hemann, M.6
Michel, L.7
Mittal, V.8
Gerald, W.9
Cordon-Cardo, C.10
-
45
-
-
3242880237
-
The emerging role of E2F-1 in the DNA damage response and checkpoint control
-
C. Stevens and N. B. La Thangue, The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair 3, 1071-1079 (2004).
-
(2004)
DNA Repair
, vol.3
, pp. 1071-1079
-
-
Stevens, C.1
La Thangue, N.B.2
-
46
-
-
33748028804
-
Cell cycle control and beyond: Emerging roles for the retinoblastoma gene family
-
C. Genovese, D. Trani, M. Caputi and P. P. Claudio, Cell cycle control and beyond: emerging roles for the retinoblastoma gene family. Oncogene 25, 5201-5209 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 5201-5209
-
-
Genovese, C.1
Trani, D.2
Caputi, M.3
Claudio, P.P.4
-
47
-
-
0027137446
-
irs-20. I. Isolation and initial characterization
-
An ionizing radiation-sensitive mutant of CHO cells
-
M. A. Stackhouse and J. S. Bedford, An ionizing radiation-sensitive mutant of CHO cells: irs-20. I. Isolation and initial characterization. Radiat. Res. 136, 241-249 (1993).
-
(1993)
Radiat. Res
, vol.136
, pp. 241-249
-
-
Stackhouse, M.A.1
Bedford, J.S.2
-
48
-
-
0027135584
-
irs-20. II. Dose-rate effects and cellular recovery processes
-
An ionizing radiation-sensitive mutant of CHO cells
-
M. A. Stackhouse and J. S. Bedford, An ionizing radiation-sensitive mutant of CHO cells: irs-20. II. Dose-rate effects and cellular recovery processes. Radiat. Res. 136, 250-254 (1993).
-
(1993)
Radiat. Res
, vol.136
, pp. 250-254
-
-
Stackhouse, M.A.1
Bedford, J.S.2
-
49
-
-
1842365517
-
irs-20. IV. Genetic complementation, V(D)J recombination, and the scid phenotype
-
An ionizing radiation-sensitive mutant CHO mutant cell line
-
J. Y-D. Lin, M. C. Mühlmann-Diaz, M. A. Stackhouse, J. E. Robinson, G. E. Taccioli, D. J. Chen and J. S. Bedford, An ionizing radiation-sensitive mutant CHO mutant cell line: irs-20. IV. Genetic complementation, V(D)J recombination, and the scid phenotype. Radiat. Res. 147, 166-171 (1997).
-
(1997)
Radiat. Res
, vol.147
, pp. 166-171
-
-
Lin, J.Y.-D.1
Mühlmann-Diaz, M.C.2
Stackhouse, M.A.3
Robinson, J.E.4
Taccioli, G.E.5
Chen, D.J.6
Bedford, J.S.7
-
50
-
-
18144452815
-
Molecular and biochemical characterization of DNA-dependent protein kinase-defective rodent mutant irs-20
-
A. Priestly, H. J. Beamish, D. Gell, A. G. Amatucci, M. C. Mühlmann-Diaz, B. K. Singleton, G. C. M. Smith, T. Blunt, L. C. Schalkwyk and G. E. Taccioli, Molecular and biochemical characterization of DNA-dependent protein kinase-defective rodent mutant irs-20. Nucleic Acids Res. 26, 1965-1973 (1998).
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1965-1973
-
-
Priestly, A.1
Beamish, H.J.2
Gell, D.3
Amatucci, A.G.4
Mühlmann-Diaz, M.C.5
Singleton, B.K.6
Smith, G.C.M.7
Blunt, T.8
Schalkwyk, L.C.9
Taccioli, G.E.10
-
51
-
-
0015877490
-
Dose-rate effects in synchronous mammalian cells in culture
-
J. S. Bedford and J. B. Mitchell, Dose-rate effects in synchronous mammalian cells in culture. Radiat. Res. 54, 316-327 (1973).
-
(1973)
Radiat. Res
, vol.54
, pp. 316-327
-
-
Bedford, J.S.1
Mitchell, J.B.2
-
52
-
-
0018320349
-
Dose-rate effects in mammalian cells in culture. III. Comparison of cell killing and cell proliferation during continuous irradiation for six different cell lines
-
J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects in mammalian cells in culture. III. Comparison of cell killing and cell proliferation during continuous irradiation for six different cell lines. Radiat. Res. 79, 537-551 (1979).
-
(1979)
Radiat. Res
, vol.79
, pp. 537-551
-
-
Mitchell, J.B.1
Bedford, J.S.2
Bailey, S.M.3
-
53
-
-
0018292480
-
Dose-rate effects on the cell cycle and survival of S3 HeLa and V79 cells
-
J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects on the cell cycle and survival of S3 HeLa and V79 cells. Radiat. Res. 79, 520-536 (1979).
-
(1979)
Radiat. Res
, vol.79
, pp. 520-536
-
-
Mitchell, J.B.1
Bedford, J.S.2
Bailey, S.M.3
-
54
-
-
0021090176
-
Recovery from lethal and mutagenic damage during postirradiation holding and low dose-rate irradiations of cultured hamster cells
-
J. Thacker and A. Stretch, Recovery from lethal and mutagenic damage during postirradiation holding and low dose-rate irradiations of cultured hamster cells. Radiat. Res. 96, 380-392 (1983).
-
(1983)
Radiat. Res
, vol.96
, pp. 380-392
-
-
Thacker, J.1
Stretch, A.2
-
55
-
-
0028832369
-
The genetic basis of cellular recovery from radiation damage: Response of the radiosensitive irs lines to low-dose-rate irradiation
-
J. Thacker and R. E. Wilkinson, The genetic basis of cellular recovery from radiation damage: response of the radiosensitive irs lines to low-dose-rate irradiation. Radiat. Res. 144, 294-300 (1995).
-
(1995)
Radiat. Res
, vol.144
, pp. 294-300
-
-
Thacker, J.1
Wilkinson, R.E.2
-
56
-
-
0027929970
-
Dose-rate effects between 0.3 and 30 Gy/h in a normal and a malignant human cell line
-
R. J. Amdur and J. S. Bedford, Dose-rate effects between 0.3 and 30 Gy/h in a normal and a malignant human cell line. Int. J. Radiat. Oncol. Biol. Phys. 30, 83-90 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys
, vol.30
, pp. 83-90
-
-
Amdur, R.J.1
Bedford, J.S.2
-
57
-
-
0029008814
-
Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: Chromosome aberrations after low dose-rate irradiation
-
L. A. Jones, D. Scott, R. Cowan and S. A. Roberts, Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose-rate irradiation. Int. J. Radiat. Biol. 67, 519-528 (1995).
-
(1995)
Int. J. Radiat. Biol
, vol.67
, pp. 519-528
-
-
Jones, L.A.1
Scott, D.2
Cowan, R.3
Roberts, S.A.4
-
58
-
-
0002642287
-
Chromosome aberrations in human lymphocytes: Effect of radiation quality, dose, and dose rate
-
T. Ishihara and M. S. Sasaki, Eds, pp, Alan R. Liss, New York
-
D. C. Lloyd and A. A. Edwards, Chromosome aberrations in human lymphocytes: effect of radiation quality, dose, and dose rate. In Radiation-Induced Chromosome Damage in Man (T. Ishihara and M. S. Sasaki, Eds.), pp. 23-49. Alan R. Liss, New York, 1983.
-
(1983)
Radiation-Induced Chromosome Damage in Man
, pp. 23-49
-
-
Lloyd, D.C.1
Edwards, A.A.2
-
60
-
-
0036300068
-
Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates
-
M. N. Cornforth, S. M. Bailey and E. H. Goodwin, Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates. Radiat. Res. 158, 43-53 (2002).
-
(2002)
Radiat. Res
, vol.158
, pp. 43-53
-
-
Cornforth, M.N.1
Bailey, S.M.2
Goodwin, E.H.3
-
61
-
-
6344263391
-
Influence of dose rate on the induction of simple and complex chromosome exchanges by gamma rays
-
B. D. Loucas, R. Eberle, S. M. Bailey and M. N. Cornforth, Influence of dose rate on the induction of simple and complex chromosome exchanges by gamma rays. Radiat. Res. 162, 339-349 (2004).
-
(2004)
Radiat. Res
, vol.162
, pp. 339-349
-
-
Loucas, B.D.1
Eberle, R.2
Bailey, S.M.3
Cornforth, M.N.4
-
62
-
-
14344257421
-
Cytotoxic and mutagenic effects of chronic low dose-rate irradiation on TERT-immortalized human cells
-
H. Nakamura, H. Fukami, Y. Hayashi, A. Tachibana, S. Nakatsugawa, M. Hamaguchi and K. Ishizaki, Cytotoxic and mutagenic effects of chronic low dose-rate irradiation on TERT-immortalized human cells. Radiat. Res. 163, 283-288 (2005).
-
(2005)
Radiat. Res
, vol.163
, pp. 283-288
-
-
Nakamura, H.1
Fukami, H.2
Hayashi, Y.3
Tachibana, A.4
Nakatsugawa, S.5
Hamaguchi, M.6
Ishizaki, K.7
-
64
-
-
33748472075
-
Levels of gamma-H2AX foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two AT families and in another apparently normal individual
-
T. A. Kato, H. Nagasawa, M. M. Weil, J. B. Little and J. S. Bedford, Levels of gamma-H2AX foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two AT families and in another apparently normal individual. Radiat. Res. 166, 443-453 (2006).
-
(2006)
Radiat. Res
, vol.166
, pp. 443-453
-
-
Kato, T.A.1
Nagasawa, H.2
Weil, M.M.3
Little, J.B.4
Bedford, J.S.5
-
65
-
-
34247582841
-
A defect in DNA double-strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans
-
T. A. Kato, P. F. Wilson, H. Nagasawa, M. M. Fitzek, M. M. Weil, J. B. Little and J. S. Bedford, A defect in DNA double-strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans. DNA Repair 6, 818-829 (2007).
-
(2007)
DNA Repair
, vol.6
, pp. 818-829
-
-
Kato, T.A.1
Wilson, P.F.2
Nagasawa, H.3
Fitzek, M.M.4
Weil, M.M.5
Little, J.B.6
Bedford, J.S.7
-
66
-
-
0026000309
-
Assessment of chronic γ radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia
-
D. E. Weeks, M. C. Paterson, K. Lange, B. Andrais, R. C. Davis, F. Yoder and R. A. Gatti, Assessment of chronic γ radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia. Radiat. Res. 128, 90-99 (1991).
-
(1991)
Radiat. Res
, vol.128
, pp. 90-99
-
-
Weeks, D.E.1
Paterson, M.C.2
Lange, K.3
Andrais, B.4
Davis, R.C.5
Yoder, F.6
Gatti, R.A.7
-
67
-
-
0027435910
-
Use of low dose-rate irradiation to measure the intrinsic radiosensitivity of human T-lymphocytes
-
S. A. G. Elyan, C. M. L. West, S. A. Roberts and R. D. Hunter, Use of low dose-rate irradiation to measure the intrinsic radiosensitivity of human T-lymphocytes. Int. J. Radiat. Biol. 64, 375-383 (1993).
-
(1993)
Int. J. Radiat. Biol
, vol.64
, pp. 375-383
-
-
Elyan, S.A.G.1
West, C.M.L.2
Roberts, S.A.3
Hunter, R.D.4
-
68
-
-
0018292242
-
Dose-rate effects in plateau-phase cultures of S3 HeLa and V79 cells
-
J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects in plateau-phase cultures of S3 HeLa and V79 cells. Radiat. Res. 79, 552-567 (1979).
-
(1979)
Radiat. Res
, vol.79
, pp. 552-567
-
-
Mitchell, J.B.1
Bedford, J.S.2
Bailey, S.M.3
-
69
-
-
0020622385
-
Dose-rate effects in mammalian cells. IV. Repairable and non-repairable damage in noncycling C3H 10T1/2cells
-
R. L. Wells and J. S. Bedford, Dose-rate effects in mammalian cells. IV. Repairable and non-repairable damage in noncycling C3H 10T1/2cells. Radiat. Res. 94, 105-134 (1983).
-
(1983)
Radiat. Res
, vol.94
, pp. 105-134
-
-
Wells, R.L.1
Bedford, J.S.2
-
70
-
-
0025836802
-
Sublethal damage, potentially lethal damage and chromosomal aberrations in mammalian cells exposed to ionizing radiations
-
J. S. Bedford, Sublethal damage, potentially lethal damage and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21, 1457-1469 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys
, vol.21
, pp. 1457-1469
-
-
Bedford, J.S.1
-
71
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
K. Rothkamm, I. Krüger, L. H. Thompson and M. Löbrich, Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 23, 5706-5715 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5706-5715
-
-
Rothkamm, K.1
Krüger, I.2
Thompson, L.H.3
Löbrich, M.4
-
72
-
-
2542478847
-
Origin, recognition, signaling, and repair of DNA double strand breaks in mammalian cells
-
K. W. Caldecott, Ed, pp, Kluwer Academic/Plenum Publishers, New York
-
L. H. Thompson and C. L. Limoli, Origin, recognition, signaling, and repair of DNA double strand breaks in mammalian cells. In Eukaryotic DNA Damage Surveillance and Repair (K. W. Caldecott, Ed.), pp. 107-145. Kluwer Academic/Plenum Publishers, New York, 2003.
-
(2003)
Eukaryotic DNA Damage Surveillance and Repair
, pp. 107-145
-
-
Thompson, L.H.1
Limoli, C.L.2
-
73
-
-
0141757494
-
Regulation and mechanisms of mammalian double-strand break repair
-
K. Valerie and L. F. Povirk, Regulation and mechanisms of mammalian double-strand break repair. Oncogene 22, 5792-5812 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 5792-5812
-
-
Valerie, K.1
Povirk, L.F.2
-
75
-
-
0002523471
-
The statistical treatment of cell survival data
-
T. Alper, Ed, Wiley, London
-
J. W. Boag, The statistical treatment of cell survival data. In Cell Survival after Low Doses of Radiation: Theoretical and Clinical Implications (T. Alper, Ed.), 40-53. Wiley, London, 1975.
-
(1975)
Cell Survival after Low Doses of Radiation: Theoretical and Clinical Implications
, pp. 40-53
-
-
Boag, J.W.1
-
76
-
-
0020594861
-
Statistical methods for in vitro cell survival assays
-
R. E. Tarone, D. A. Scudiero and J. H. Robbins, Statistical methods for in vitro cell survival assays. Mutat. Res. 111, 79-96 (1983).
-
(1983)
Mutat. Res
, vol.111
, pp. 79-96
-
-
Tarone, R.E.1
Scudiero, D.A.2
Robbins, J.H.3
-
77
-
-
0032757671
-
Relationships between colony forming efficiency and parameters of intrinsic radiosensitivity
-
B. Fertil and P. J. Deschavanne, Relationships between colony forming efficiency and parameters of intrinsic radiosensitivity. Int. J. Radiat. Biol. 75, 1275-1282 (1999).
-
(1999)
Int. J. Radiat. Biol
, vol.75
, pp. 1275-1282
-
-
Fertil, B.1
Deschavanne, P.J.2
-
78
-
-
0037891337
-
Variations in responses of several mammalian cell lines to low dose-rate irradiation
-
R. E. Meyn and H. R. Withers, Eds, pp, Elsevier, Amsterdam
-
J. S. Bedford, J. B. Mitchell and M. H. Fox, Variations in responses of several mammalian cell lines to low dose-rate irradiation. In Radiation Biology in Cancer Research (R. E. Meyn and H. R. Withers, Eds.), pp. 251-262. Elsevier, Amsterdam, 1980.
-
(1980)
Radiation Biology in Cancer Research
, pp. 251-262
-
-
Bedford, J.S.1
Mitchell, J.B.2
Fox, M.H.3
-
79
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
T. Lindahl, Instability and decay of the primary structure of DNA. Nature 362, 709-715 (1993).
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
80
-
-
43449089372
-
-
J. F. Ward, Nature of lesions formed by ionizing radiation. In DNA Damage and Repair, II: DNA Repair in Higher Eukaryotes (J. A. Nickoloff and M. F. Hoekstra, Eds.), pp. 65-84. Springer, Berlin, 1998.
-
J. F. Ward, Nature of lesions formed by ionizing radiation. In DNA Damage and Repair, Volume II: DNA Repair in Higher Eukaryotes (J. A. Nickoloff and M. F. Hoekstra, Eds.), pp. 65-84. Springer, Berlin, 1998.
-
-
-
-
81
-
-
0242300088
-
Production, fidelity of repair, and induction of cancer
-
Endogenous DNA double-strand breaks
-
M. M. Vilenchik and A. G. Knudson, Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer. Proc. Natl. Acad. Sci. USA 100, 12871-12876 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12871-12876
-
-
Vilenchik, M.M.1
Knudson, A.G.2
-
82
-
-
0036267443
-
Clustered DNA damages induced by X rays in human cells
-
B. M. Sutherland, P. V. Bennett, J. C. Sutherland and J. Laval, Clustered DNA damages induced by X rays in human cells. Radiat. Res. 157, 611-616 (2002).
-
(2002)
Radiat. Res
, vol.157
, pp. 611-616
-
-
Sutherland, B.M.1
Bennett, P.V.2
Sutherland, J.C.3
Laval, J.4
-
83
-
-
2542637919
-
Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
-
M. Gulston, C. de Lara, T. Jenner, E. Davis and P. O'Neill, Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 32, 1602-1609 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 1602-1609
-
-
Gulston, M.1
de Lara, C.2
Jenner, T.3
Davis, E.4
O'Neill, P.5
-
84
-
-
0001205905
-
Track structure considerations in low dose and low dose rate effects of ionizing radiation
-
D. T. Goodhead, Track structure considerations in low dose and low dose rate effects of ionizing radiation. Adv. Radiat. Biol. 16, 7-44 (1992).
-
(1992)
Adv. Radiat. Biol
, vol.16
, pp. 7-44
-
-
Goodhead, D.T.1
-
85
-
-
0037884963
-
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
-
K. Rothkamm and M. Löbrich, Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl. Acad. Sci. USA 100, 5057-5062 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5057-5062
-
-
Rothkamm, K.1
Löbrich, M.2
-
86
-
-
9644278078
-
Evasion of early cellular response mechanisms following low level radiation-induced DNA damage
-
S. J. Collis, J. M. Schwaninger, A. J. Ntambi, T. W. Keller, W. G. Nelson, L. E. Dillehay and T. L. De Weese, Evasion of early cellular response mechanisms following low level radiation-induced DNA damage. J. Biol. Chem. 279, 49624-49632 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49624-49632
-
-
Collis, S.J.1
Schwaninger, J.M.2
Ntambi, A.J.3
Keller, T.W.4
Nelson, W.G.5
Dillehay, L.E.6
De Weese, T.L.7
-
87
-
-
13844294491
-
No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low dose-rate irradiation in human cells
-
K. Ishizaki, Y. Hayashi, H. Nakamura, Y. Yasui, K. Komatsu and A. Tachibana, No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low dose-rate irradiation in human cells. J. Radiat. Res. 45, 521-525 (2004).
-
(2004)
J. Radiat. Res
, vol.45
, pp. 521-525
-
-
Ishizaki, K.1
Hayashi, Y.2
Nakamura, H.3
Yasui, Y.4
Komatsu, K.5
Tachibana, A.6
-
88
-
-
4644336002
-
Dose and dose-rate effects of low-dose ionizing radiation on the activation of trp53 in immortalized murine cells
-
T. Sugihara, J. Magae, R. Wadhwa, S. C. Kaul, Y. Kawakami, T. Matsumoto and K. Tanaka, Dose and dose-rate effects of low-dose ionizing radiation on the activation of trp53 in immortalized murine cells. Radiat. Res. 162, 296-307 (2004).
-
(2004)
Radiat. Res
, vol.162
, pp. 296-307
-
-
Sugihara, T.1
Magae, J.2
Wadhwa, R.3
Kaul, S.C.4
Kawakami, Y.5
Matsumoto, T.6
Tanaka, K.7
-
89
-
-
0031900748
-
Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines
-
E. Dikomey, J. Dahm-Daphi, I. Brammer, R. Martensen and B. Kaina, Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines. Int. J. Radiat. Biol. 73, 269-278 (1998).
-
(1998)
Int. J. Radiat. Biol
, vol.73
, pp. 269-278
-
-
Dikomey, E.1
Dahm-Daphi, J.2
Brammer, I.3
Martensen, R.4
Kaina, B.5
-
90
-
-
0034129412
-
Relationship between cellular radiosensitivity and non-repaired double-strand breaks studied for different growth states, dose rates and plating conditions in a normal human fibroblast line
-
E. Dikomey and I. Brammer, Relationship between cellular radiosensitivity and non-repaired double-strand breaks studied for different growth states, dose rates and plating conditions in a normal human fibroblast line. Int. J. Radiat. Biol. 76, 773-781 (2000).
-
(2000)
Int. J. Radiat. Biol
, vol.76
, pp. 773-781
-
-
Dikomey, E.1
Brammer, I.2
-
91
-
-
0035093737
-
signaling, repair and the cancer connection
-
DNA double-strand breaks
-
K. K. Khanna and S. P. Jackson, DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27, 247-254 (2001).
-
(2001)
Nat. Genet
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
92
-
-
0035289717
-
Chromosomal stability and the double-stranded break connection
-
D. C. van Gent, J. H. Hoeijmakers and R. Kanaar, Chromosomal stability and the double-stranded break connection. Nat. Rev. Genet. 2, 196-206 (2001).
-
(2001)
Nat. Rev. Genet
, vol.2
, pp. 196-206
-
-
van Gent, D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
93
-
-
0034624963
-
Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates
-
M. M. Vilenchik and A. G. Knudson, Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates. Proc. Natl. Acad. Sci. USA 97, 5381-5386 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5381-5386
-
-
Vilenchik, M.M.1
Knudson, A.G.2
-
94
-
-
33845232990
-
Radiation dose-rate effects, endogenous DNA damage and signaling resonance
-
M. M. Vilenchik and A. G. Knudson, Radiation dose-rate effects, endogenous DNA damage and signaling resonance. Proc. Natl. Acad. Sci. USA 103, 17874-17879 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 17874-17879
-
-
Vilenchik, M.M.1
Knudson, A.G.2
-
95
-
-
0028827582
-
Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines
-
C-Y. Li, H. Nagasawa, W. K. Dahlberg and J. B. Little, Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines. Oncogene 11, 1885-1892 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 1885-1892
-
-
Li, C.-Y.1
Nagasawa, H.2
Dahlberg, W.K.3
Little, J.B.4
|