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Volumn 169, Issue 5, 2008, Pages 483-494

Radiation sensitivity of primary fibroblasts from hereditary retinoblastoma family members and some apparently normal controls: Colony formation ability during continuous low-dose-rate gamma irradiation

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CELL CYCLE G1 PHASE; CELL KILLING; CELL SURVIVAL; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; DNA REPAIR; FEMALE; FIBROBLAST; GAMMA RADIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; INFANT; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIATION DOSE; RADIOSENSITIVITY; RETINOBLASTOMA;

EID: 43449108282     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1333.1     Document Type: Article
Times cited : (17)

References (95)
  • 1
    • 0036114263 scopus 로고    scopus 로고
    • Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma
    • M. M. Fitzek, W. K. Dahlberg, H. Nagasawa, S. Mukai, J. E. Munzenrider and J. B. Little, Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma. Int. J. Cancer 99, 764-768 (2002).
    • (2002) Int. J. Cancer , vol.99 , pp. 764-768
    • Fitzek, M.M.1    Dahlberg, W.K.2    Nagasawa, H.3    Mukai, S.4    Munzenrider, J.E.5    Little, J.B.6
  • 3
    • 3242876404 scopus 로고    scopus 로고
    • Ataxia-telangiectasia, an evolving phenotype
    • H. H. Chun and R. A. Gatti, Ataxia-telangiectasia, an evolving phenotype. DNA Repair 3, 1187-1196 (2004).
    • (2004) DNA Repair , vol.3 , pp. 1187-1196
    • Chun, H.H.1    Gatti, R.A.2
  • 4
    • 3242889151 scopus 로고    scopus 로고
    • Ataxia-telangiectasia-like disorder (ATLD) - its clinical presentation and molecular basis
    • A. M. R. Taylor, A. Groom and P. J. Byrd. Ataxia-telangiectasia-like disorder (ATLD) - its clinical presentation and molecular basis. DNA Repair 3, 1219-1225 (2004).
    • (2004) DNA Repair , vol.3 , pp. 1219-1225
    • Taylor, A.M.R.1    Groom, A.2    Byrd, P.J.3
  • 5
    • 3242892589 scopus 로고    scopus 로고
    • Nijmegen breakage syndrome: Clinical manifestation of defective response to DNA double-strand breaks
    • M. Digweed and K. Sperling, Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair 3, 1207-1217 (2004).
    • (2004) DNA Repair , vol.3 , pp. 1207-1217
    • Digweed, M.1    Sperling, K.2
  • 7
    • 0027473181 scopus 로고
    • Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: A comprehensive survey of genetic and biochemical characteristics
    • A. R. Collins, Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res. DNA Repair 293, 99-118 (1993).
    • (1993) Mutat. Res. DNA Repair , vol.293 , pp. 99-118
    • Collins, A.R.1
  • 8
    • 20644450114 scopus 로고    scopus 로고
    • Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells
    • J. M. Hinz, N. A. Yamada, E. P. Salazar, R. S. Tebbs and L. H. Thompson, Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells. DNA Repair 4, 782-792 (2005).
    • (2005) DNA Repair , vol.4 , pp. 782-792
    • Hinz, J.M.1    Yamada, N.A.2    Salazar, E.P.3    Tebbs, R.S.4    Thompson, L.H.5
  • 10
    • 0035328461 scopus 로고    scopus 로고
    • Evidence of DNA repair/processing defects in cultured skin fibroblasts from breast cancer patients
    • M. A. Hannan, Y. Siddiqui, A. Rostom, M. N. Al-Ahdal, M. A. Chaudhary and M. Kunhi, Evidence of DNA repair/processing defects in cultured skin fibroblasts from breast cancer patients. Cancer Res. 61, 3627-3631 (2001).
    • (2001) Cancer Res , vol.61 , pp. 3627-3631
    • Hannan, M.A.1    Siddiqui, Y.2    Rostom, A.3    Al-Ahdal, M.N.4    Chaudhary, M.A.5    Kunhi, M.6
  • 11
    • 2642525186 scopus 로고    scopus 로고
    • Chromosomal radiosensitivity and low penetrance predisposition to cancer
    • D. Scott, Chromosomal radiosensitivity and low penetrance predisposition to cancer. Cytogenet. Genome Res. 104, 365-370 (2004).
    • (2004) Cytogenet. Genome Res , vol.104 , pp. 365-370
    • Scott, D.1
  • 12
    • 0018653177 scopus 로고
    • G2 chromosomal radiosensitivity in Fanconi's anemia
    • S. B. Bigelow, J. M. Rary and M. A. Bender, G2 chromosomal radiosensitivity in Fanconi's anemia. Mutat. Res. 63, 189-199 (1979).
    • (1979) Mutat. Res , vol.63 , pp. 189-199
    • Bigelow, S.B.1    Rary, J.M.2    Bender, M.A.3
  • 14
    • 0018890926 scopus 로고
    • X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders
    • R. R. Weichselbaum, J. Nove and J. B. Little, X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders. Cancer Res. 40, 920-925 (1980).
    • (1980) Cancer Res , vol.40 , pp. 920-925
    • Weichselbaum, R.R.1    Nove, J.2    Little, J.B.3
  • 15
    • 0020587099 scopus 로고
    • Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts
    • H. Nagasawa and J. B. Little, Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts. Mutat. Res. 109, 297-308 (1983).
    • (1983) Mutat. Res , vol.109 , pp. 297-308
    • Nagasawa, H.1    Little, J.B.2
  • 16
    • 0023223245 scopus 로고
    • X-radiation-induced chromosome breakage in retinoblastoma lymphocytes
    • J. G. Heras and R. Coco, X-radiation-induced chromosome breakage in retinoblastoma lymphocytes. Mutat. Res. 178, 225-233 (1987).
    • (1987) Mutat. Res , vol.178 , pp. 225-233
    • Heras, J.G.1    Coco, R.2
  • 17
    • 0023176338 scopus 로고
    • X-ray sensitivity of fibroblasts from patients with hereditary retinoblastoma and their families
    • J. V. Pledger, A. W. Craft, K. Bartlett and D. R. Long, X-ray sensitivity of fibroblasts from patients with hereditary retinoblastoma and their families. Br. J. Cancer 55, 617-621 (1987).
    • (1987) Br. J. Cancer , vol.55 , pp. 617-621
    • Pledger, J.V.1    Craft, A.W.2    Bartlett, K.3    Long, D.R.4
  • 18
    • 0024309898 scopus 로고
    • Radiation sensitivity of cell strains from families with genetic disorders predisposing to radiation-induced cancer
    • J. B. Little, W. W. Nichols, P. Troilo, H. Nagasawa and L. C. Strong, Radiation sensitivity of cell strains from families with genetic disorders predisposing to radiation-induced cancer. Cancer Res. 49, 4705-4714 (1989).
    • (1989) Cancer Res , vol.49 , pp. 4705-4714
    • Little, J.B.1    Nichols, W.W.2    Troilo, P.3    Nagasawa, H.4    Strong, L.C.5
  • 19
    • 0025345637 scopus 로고
    • Sensitivity of human diploid fibroblast cell strains from various genetics disorders to acute and protracted radiation exposure
    • J. B. Little and J. Nove, Sensitivity of human diploid fibroblast cell strains from various genetics disorders to acute and protracted radiation exposure. Radiat. Res. 123, 87-92 (1990).
    • (1990) Radiat. Res , vol.123 , pp. 87-92
    • Little, J.B.1    Nove, J.2
  • 24
    • 0018837288 scopus 로고
    • Survey of radiosensitivity in a variety of human cell strains
    • C. F. Arlett and S. A. Harcourt, Survey of radiosensitivity in a variety of human cell strains. Cancer Res. 40, 926-932 (1980).
    • (1980) Cancer Res , vol.40 , pp. 926-932
    • Arlett, C.F.1    Harcourt, S.A.2
  • 25
    • 0023766336 scopus 로고
    • 2-phase chromosomal aberrations and cell cycle delay
    • 2-phase chromosomal aberrations and cell cycle delay. Cancer Res. 48, 4535-4538 (1988).
    • (1988) Cancer Res , vol.48 , pp. 4535-4538
    • Nagasawa, H.1    Little, J.B.2
  • 27
    • 0242268054 scopus 로고    scopus 로고
    • Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts
    • E. Dikomey, K. Borgmann, I. Brammer and U. Kasten-Pisula, Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts. Toxicology 198, 125-135 (2003).
    • (2003) Toxicology , vol.198 , pp. 125-135
    • Dikomey, E.1    Borgmann, K.2    Brammer, I.3    Kasten-Pisula, U.4
  • 28
    • 0242501504 scopus 로고    scopus 로고
    • Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes
    • H. W. Mohrenweiser, D. M. Wilson, III and I. M. Jones, Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat. Res. 526, 93-125 (2003).
    • (2003) Mutat. Res , vol.526 , pp. 93-125
    • Mohrenweiser, H.W.1    Wilson III, D.M.2    Jones, I.M.3
  • 29
    • 2642527702 scopus 로고    scopus 로고
    • Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
    • T. Xi, I. M. Jones and H. W. Mohrenweiser, Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function. Genomics 83, 970-979 (2004).
    • (2004) Genomics , vol.83 , pp. 970-979
    • Xi, T.1    Jones, I.M.2    Mohrenweiser, H.W.3
  • 30
    • 3242876403 scopus 로고    scopus 로고
    • Genetic biomarkers of therapeutic radiation sensitivity
    • M. Fernet and J. Hall, Genetic biomarkers of therapeutic radiation sensitivity. DNA Repair 3, 1237-1243 (2004).
    • (2004) DNA Repair , vol.3 , pp. 1237-1243
    • Fernet, M.1    Hall, J.2
  • 31
    • 26444479826 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk
    • R. C. Millikan, J. S. Player, A. R. de Cotret, C-K. Tse and T. Keku, Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 14, 2326-2334 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , pp. 2326-2334
    • Millikan, R.C.1    Player, J.S.2    de Cotret, A.R.3    Tse, C.-K.4    Keku, T.5
  • 32
    • 27844576828 scopus 로고    scopus 로고
    • Huge differences in cellular radiosensitivity due to only very small variations in doublestrand break repair capacity
    • U. Kasten-Pisula, H. Tastan and E. Dikomey, Huge differences in cellular radiosensitivity due to only very small variations in doublestrand break repair capacity. Int. J. Radiat. Biol. 81, 409-419 (2005).
    • (2005) Int. J. Radiat. Biol , vol.81 , pp. 409-419
    • Kasten-Pisula, U.1    Tastan, H.2    Dikomey, E.3
  • 33
    • 0036669735 scopus 로고    scopus 로고
    • Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look or it?
    • C. N. Andreassen, J. Alsner and J. Overgaard, Does variability in normal tissue reactions after radiotherapy have a genetic basis - where and how to look or it? Radiother. Oncol. 64, 131-140 (2002).
    • (2002) Radiother. Oncol , vol.64 , pp. 131-140
    • Andreassen, C.N.1    Alsner, J.2    Overgaard, J.3
  • 34
    • 0029840089 scopus 로고    scopus 로고
    • Low dose-rate fibroblast radiosensitivity and the prediction of patient response to radiotherapy
    • N. G. Burnet, R. Wurm and J. H. Peacock, Low dose-rate fibroblast radiosensitivity and the prediction of patient response to radiotherapy. Int. J. Radiat. Biol. 70, 289-300 (1996).
    • (1996) Int. J. Radiat. Biol , vol.70 , pp. 289-300
    • Burnet, N.G.1    Wurm, R.2    Peacock, J.H.3
  • 35
    • 0018642114 scopus 로고
    • Genetics of retinoblastoma
    • F. Vogel, Genetics of retinoblastoma. Hum. Genet. 52, 1-54 (1979).
    • (1979) Hum. Genet , vol.52 , pp. 1-54
    • Vogel, F.1
  • 36
    • 0027172571 scopus 로고    scopus 로고
    • C. Eng, F. P. Li, D. H. Abramson, R. M. Ellsworth, F. L. Wong, M. B. Goldman, J. Seddon, N. Tarbell and J. D. Boice, Jr., Mortality from second tumors among long-term survivors of retinoblastoma. J. Natl. Cancer Inst. 85, 1121-1128 (1993).
    • C. Eng, F. P. Li, D. H. Abramson, R. M. Ellsworth, F. L. Wong, M. B. Goldman, J. Seddon, N. Tarbell and J. D. Boice, Jr., Mortality from second tumors among long-term survivors of retinoblastoma. J. Natl. Cancer Inst. 85, 1121-1128 (1993).
  • 38
    • 17144398035 scopus 로고    scopus 로고
    • R. A. Kleinerman, M. A. Tucker, R. E. Tarone, D. H. Abramson, J. M. Seddon, M. Stovall, F. P. Li and J. F. Fraumeni, Jr., Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J. Clin. Oncol. 23, 2272-2279 (2005).
    • R. A. Kleinerman, M. A. Tucker, R. E. Tarone, D. H. Abramson, J. M. Seddon, M. Stovall, F. P. Li and J. F. Fraumeni, Jr., Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up. J. Clin. Oncol. 23, 2272-2279 (2005).
  • 42
    • 0036386059 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor and genome stability
    • L. Zheng and W-H. Lee, Retinoblastoma tumor suppressor and genome stability. Adv. Cancer Res. 85, 13-50 (2002).
    • (2002) Adv. Cancer Res , vol.85 , pp. 13-50
    • Zheng, L.1    Lee, W.-H.2
  • 43
    • 0036569924 scopus 로고    scopus 로고
    • Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability
    • L. Zheng, A. Flesken-Nikitin, P-L. Chen and W-H. Lee, Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability. Cancer Res. 62, 2498-2502 (2002).
    • (2002) Cancer Res , vol.62 , pp. 2498-2502
    • Zheng, L.1    Flesken-Nikitin, A.2    Chen, P.-L.3    Lee, W.-H.4
  • 45
    • 3242880237 scopus 로고    scopus 로고
    • The emerging role of E2F-1 in the DNA damage response and checkpoint control
    • C. Stevens and N. B. La Thangue, The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair 3, 1071-1079 (2004).
    • (2004) DNA Repair , vol.3 , pp. 1071-1079
    • Stevens, C.1    La Thangue, N.B.2
  • 46
    • 33748028804 scopus 로고    scopus 로고
    • Cell cycle control and beyond: Emerging roles for the retinoblastoma gene family
    • C. Genovese, D. Trani, M. Caputi and P. P. Claudio, Cell cycle control and beyond: emerging roles for the retinoblastoma gene family. Oncogene 25, 5201-5209 (2006).
    • (2006) Oncogene , vol.25 , pp. 5201-5209
    • Genovese, C.1    Trani, D.2    Caputi, M.3    Claudio, P.P.4
  • 47
    • 0027137446 scopus 로고
    • irs-20. I. Isolation and initial characterization
    • An ionizing radiation-sensitive mutant of CHO cells
    • M. A. Stackhouse and J. S. Bedford, An ionizing radiation-sensitive mutant of CHO cells: irs-20. I. Isolation and initial characterization. Radiat. Res. 136, 241-249 (1993).
    • (1993) Radiat. Res , vol.136 , pp. 241-249
    • Stackhouse, M.A.1    Bedford, J.S.2
  • 48
    • 0027135584 scopus 로고
    • irs-20. II. Dose-rate effects and cellular recovery processes
    • An ionizing radiation-sensitive mutant of CHO cells
    • M. A. Stackhouse and J. S. Bedford, An ionizing radiation-sensitive mutant of CHO cells: irs-20. II. Dose-rate effects and cellular recovery processes. Radiat. Res. 136, 250-254 (1993).
    • (1993) Radiat. Res , vol.136 , pp. 250-254
    • Stackhouse, M.A.1    Bedford, J.S.2
  • 49
    • 1842365517 scopus 로고    scopus 로고
    • irs-20. IV. Genetic complementation, V(D)J recombination, and the scid phenotype
    • An ionizing radiation-sensitive mutant CHO mutant cell line
    • J. Y-D. Lin, M. C. Mühlmann-Diaz, M. A. Stackhouse, J. E. Robinson, G. E. Taccioli, D. J. Chen and J. S. Bedford, An ionizing radiation-sensitive mutant CHO mutant cell line: irs-20. IV. Genetic complementation, V(D)J recombination, and the scid phenotype. Radiat. Res. 147, 166-171 (1997).
    • (1997) Radiat. Res , vol.147 , pp. 166-171
    • Lin, J.Y.-D.1    Mühlmann-Diaz, M.C.2    Stackhouse, M.A.3    Robinson, J.E.4    Taccioli, G.E.5    Chen, D.J.6    Bedford, J.S.7
  • 51
    • 0015877490 scopus 로고
    • Dose-rate effects in synchronous mammalian cells in culture
    • J. S. Bedford and J. B. Mitchell, Dose-rate effects in synchronous mammalian cells in culture. Radiat. Res. 54, 316-327 (1973).
    • (1973) Radiat. Res , vol.54 , pp. 316-327
    • Bedford, J.S.1    Mitchell, J.B.2
  • 52
    • 0018320349 scopus 로고
    • Dose-rate effects in mammalian cells in culture. III. Comparison of cell killing and cell proliferation during continuous irradiation for six different cell lines
    • J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects in mammalian cells in culture. III. Comparison of cell killing and cell proliferation during continuous irradiation for six different cell lines. Radiat. Res. 79, 537-551 (1979).
    • (1979) Radiat. Res , vol.79 , pp. 537-551
    • Mitchell, J.B.1    Bedford, J.S.2    Bailey, S.M.3
  • 53
    • 0018292480 scopus 로고
    • Dose-rate effects on the cell cycle and survival of S3 HeLa and V79 cells
    • J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects on the cell cycle and survival of S3 HeLa and V79 cells. Radiat. Res. 79, 520-536 (1979).
    • (1979) Radiat. Res , vol.79 , pp. 520-536
    • Mitchell, J.B.1    Bedford, J.S.2    Bailey, S.M.3
  • 54
    • 0021090176 scopus 로고
    • Recovery from lethal and mutagenic damage during postirradiation holding and low dose-rate irradiations of cultured hamster cells
    • J. Thacker and A. Stretch, Recovery from lethal and mutagenic damage during postirradiation holding and low dose-rate irradiations of cultured hamster cells. Radiat. Res. 96, 380-392 (1983).
    • (1983) Radiat. Res , vol.96 , pp. 380-392
    • Thacker, J.1    Stretch, A.2
  • 55
    • 0028832369 scopus 로고
    • The genetic basis of cellular recovery from radiation damage: Response of the radiosensitive irs lines to low-dose-rate irradiation
    • J. Thacker and R. E. Wilkinson, The genetic basis of cellular recovery from radiation damage: response of the radiosensitive irs lines to low-dose-rate irradiation. Radiat. Res. 144, 294-300 (1995).
    • (1995) Radiat. Res , vol.144 , pp. 294-300
    • Thacker, J.1    Wilkinson, R.E.2
  • 56
    • 0027929970 scopus 로고
    • Dose-rate effects between 0.3 and 30 Gy/h in a normal and a malignant human cell line
    • R. J. Amdur and J. S. Bedford, Dose-rate effects between 0.3 and 30 Gy/h in a normal and a malignant human cell line. Int. J. Radiat. Oncol. Biol. Phys. 30, 83-90 (1994).
    • (1994) Int. J. Radiat. Oncol. Biol. Phys , vol.30 , pp. 83-90
    • Amdur, R.J.1    Bedford, J.S.2
  • 57
    • 0029008814 scopus 로고
    • Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: Chromosome aberrations after low dose-rate irradiation
    • L. A. Jones, D. Scott, R. Cowan and S. A. Roberts, Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose-rate irradiation. Int. J. Radiat. Biol. 67, 519-528 (1995).
    • (1995) Int. J. Radiat. Biol , vol.67 , pp. 519-528
    • Jones, L.A.1    Scott, D.2    Cowan, R.3    Roberts, S.A.4
  • 58
    • 0002642287 scopus 로고
    • Chromosome aberrations in human lymphocytes: Effect of radiation quality, dose, and dose rate
    • T. Ishihara and M. S. Sasaki, Eds, pp, Alan R. Liss, New York
    • D. C. Lloyd and A. A. Edwards, Chromosome aberrations in human lymphocytes: effect of radiation quality, dose, and dose rate. In Radiation-Induced Chromosome Damage in Man (T. Ishihara and M. S. Sasaki, Eds.), pp. 23-49. Alan R. Liss, New York, 1983.
    • (1983) Radiation-Induced Chromosome Damage in Man , pp. 23-49
    • Lloyd, D.C.1    Edwards, A.A.2
  • 60
    • 0036300068 scopus 로고    scopus 로고
    • Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates
    • M. N. Cornforth, S. M. Bailey and E. H. Goodwin, Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates. Radiat. Res. 158, 43-53 (2002).
    • (2002) Radiat. Res , vol.158 , pp. 43-53
    • Cornforth, M.N.1    Bailey, S.M.2    Goodwin, E.H.3
  • 61
    • 6344263391 scopus 로고    scopus 로고
    • Influence of dose rate on the induction of simple and complex chromosome exchanges by gamma rays
    • B. D. Loucas, R. Eberle, S. M. Bailey and M. N. Cornforth, Influence of dose rate on the induction of simple and complex chromosome exchanges by gamma rays. Radiat. Res. 162, 339-349 (2004).
    • (2004) Radiat. Res , vol.162 , pp. 339-349
    • Loucas, B.D.1    Eberle, R.2    Bailey, S.M.3    Cornforth, M.N.4
  • 62
  • 64
    • 33748472075 scopus 로고    scopus 로고
    • Levels of gamma-H2AX foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two AT families and in another apparently normal individual
    • T. A. Kato, H. Nagasawa, M. M. Weil, J. B. Little and J. S. Bedford, Levels of gamma-H2AX foci after low-dose-rate irradiation reveal a DNA DSB rejoining defect in cells from human ATM heterozygotes in two AT families and in another apparently normal individual. Radiat. Res. 166, 443-453 (2006).
    • (2006) Radiat. Res , vol.166 , pp. 443-453
    • Kato, T.A.1    Nagasawa, H.2    Weil, M.M.3    Little, J.B.4    Bedford, J.S.5
  • 65
    • 34247582841 scopus 로고    scopus 로고
    • A defect in DNA double-strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans
    • T. A. Kato, P. F. Wilson, H. Nagasawa, M. M. Fitzek, M. M. Weil, J. B. Little and J. S. Bedford, A defect in DNA double-strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans. DNA Repair 6, 818-829 (2007).
    • (2007) DNA Repair , vol.6 , pp. 818-829
    • Kato, T.A.1    Wilson, P.F.2    Nagasawa, H.3    Fitzek, M.M.4    Weil, M.M.5    Little, J.B.6    Bedford, J.S.7
  • 66
    • 0026000309 scopus 로고
    • Assessment of chronic γ radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia
    • D. E. Weeks, M. C. Paterson, K. Lange, B. Andrais, R. C. Davis, F. Yoder and R. A. Gatti, Assessment of chronic γ radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia. Radiat. Res. 128, 90-99 (1991).
    • (1991) Radiat. Res , vol.128 , pp. 90-99
    • Weeks, D.E.1    Paterson, M.C.2    Lange, K.3    Andrais, B.4    Davis, R.C.5    Yoder, F.6    Gatti, R.A.7
  • 67
    • 0027435910 scopus 로고
    • Use of low dose-rate irradiation to measure the intrinsic radiosensitivity of human T-lymphocytes
    • S. A. G. Elyan, C. M. L. West, S. A. Roberts and R. D. Hunter, Use of low dose-rate irradiation to measure the intrinsic radiosensitivity of human T-lymphocytes. Int. J. Radiat. Biol. 64, 375-383 (1993).
    • (1993) Int. J. Radiat. Biol , vol.64 , pp. 375-383
    • Elyan, S.A.G.1    West, C.M.L.2    Roberts, S.A.3    Hunter, R.D.4
  • 68
    • 0018292242 scopus 로고
    • Dose-rate effects in plateau-phase cultures of S3 HeLa and V79 cells
    • J. B. Mitchell, J. S. Bedford and S. M. Bailey, Dose-rate effects in plateau-phase cultures of S3 HeLa and V79 cells. Radiat. Res. 79, 552-567 (1979).
    • (1979) Radiat. Res , vol.79 , pp. 552-567
    • Mitchell, J.B.1    Bedford, J.S.2    Bailey, S.M.3
  • 69
    • 0020622385 scopus 로고
    • Dose-rate effects in mammalian cells. IV. Repairable and non-repairable damage in noncycling C3H 10T1/2cells
    • R. L. Wells and J. S. Bedford, Dose-rate effects in mammalian cells. IV. Repairable and non-repairable damage in noncycling C3H 10T1/2cells. Radiat. Res. 94, 105-134 (1983).
    • (1983) Radiat. Res , vol.94 , pp. 105-134
    • Wells, R.L.1    Bedford, J.S.2
  • 70
    • 0025836802 scopus 로고
    • Sublethal damage, potentially lethal damage and chromosomal aberrations in mammalian cells exposed to ionizing radiations
    • J. S. Bedford, Sublethal damage, potentially lethal damage and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21, 1457-1469 (1991).
    • (1991) Int. J. Radiat. Oncol. Biol. Phys , vol.21 , pp. 1457-1469
    • Bedford, J.S.1
  • 71
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • K. Rothkamm, I. Krüger, L. H. Thompson and M. Löbrich, Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol. Cell. Biol. 23, 5706-5715 (2003).
    • (2003) Mol. Cell. Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Krüger, I.2    Thompson, L.H.3    Löbrich, M.4
  • 72
    • 2542478847 scopus 로고    scopus 로고
    • Origin, recognition, signaling, and repair of DNA double strand breaks in mammalian cells
    • K. W. Caldecott, Ed, pp, Kluwer Academic/Plenum Publishers, New York
    • L. H. Thompson and C. L. Limoli, Origin, recognition, signaling, and repair of DNA double strand breaks in mammalian cells. In Eukaryotic DNA Damage Surveillance and Repair (K. W. Caldecott, Ed.), pp. 107-145. Kluwer Academic/Plenum Publishers, New York, 2003.
    • (2003) Eukaryotic DNA Damage Surveillance and Repair , pp. 107-145
    • Thompson, L.H.1    Limoli, C.L.2
  • 73
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • K. Valerie and L. F. Povirk, Regulation and mechanisms of mammalian double-strand break repair. Oncogene 22, 5792-5812 (2003).
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 76
    • 0020594861 scopus 로고
    • Statistical methods for in vitro cell survival assays
    • R. E. Tarone, D. A. Scudiero and J. H. Robbins, Statistical methods for in vitro cell survival assays. Mutat. Res. 111, 79-96 (1983).
    • (1983) Mutat. Res , vol.111 , pp. 79-96
    • Tarone, R.E.1    Scudiero, D.A.2    Robbins, J.H.3
  • 77
    • 0032757671 scopus 로고    scopus 로고
    • Relationships between colony forming efficiency and parameters of intrinsic radiosensitivity
    • B. Fertil and P. J. Deschavanne, Relationships between colony forming efficiency and parameters of intrinsic radiosensitivity. Int. J. Radiat. Biol. 75, 1275-1282 (1999).
    • (1999) Int. J. Radiat. Biol , vol.75 , pp. 1275-1282
    • Fertil, B.1    Deschavanne, P.J.2
  • 78
    • 0037891337 scopus 로고
    • Variations in responses of several mammalian cell lines to low dose-rate irradiation
    • R. E. Meyn and H. R. Withers, Eds, pp, Elsevier, Amsterdam
    • J. S. Bedford, J. B. Mitchell and M. H. Fox, Variations in responses of several mammalian cell lines to low dose-rate irradiation. In Radiation Biology in Cancer Research (R. E. Meyn and H. R. Withers, Eds.), pp. 251-262. Elsevier, Amsterdam, 1980.
    • (1980) Radiation Biology in Cancer Research , pp. 251-262
    • Bedford, J.S.1    Mitchell, J.B.2    Fox, M.H.3
  • 79
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • T. Lindahl, Instability and decay of the primary structure of DNA. Nature 362, 709-715 (1993).
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 80
    • 43449089372 scopus 로고    scopus 로고
    • J. F. Ward, Nature of lesions formed by ionizing radiation. In DNA Damage and Repair, II: DNA Repair in Higher Eukaryotes (J. A. Nickoloff and M. F. Hoekstra, Eds.), pp. 65-84. Springer, Berlin, 1998.
    • J. F. Ward, Nature of lesions formed by ionizing radiation. In DNA Damage and Repair, Volume II: DNA Repair in Higher Eukaryotes (J. A. Nickoloff and M. F. Hoekstra, Eds.), pp. 65-84. Springer, Berlin, 1998.
  • 81
    • 0242300088 scopus 로고    scopus 로고
    • Production, fidelity of repair, and induction of cancer
    • Endogenous DNA double-strand breaks
    • M. M. Vilenchik and A. G. Knudson, Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer. Proc. Natl. Acad. Sci. USA 100, 12871-12876 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12871-12876
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 83
    • 2542637919 scopus 로고    scopus 로고
    • Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
    • M. Gulston, C. de Lara, T. Jenner, E. Davis and P. O'Neill, Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 32, 1602-1609 (2004).
    • (2004) Nucleic Acids Res , vol.32 , pp. 1602-1609
    • Gulston, M.1    de Lara, C.2    Jenner, T.3    Davis, E.4    O'Neill, P.5
  • 84
    • 0001205905 scopus 로고
    • Track structure considerations in low dose and low dose rate effects of ionizing radiation
    • D. T. Goodhead, Track structure considerations in low dose and low dose rate effects of ionizing radiation. Adv. Radiat. Biol. 16, 7-44 (1992).
    • (1992) Adv. Radiat. Biol , vol.16 , pp. 7-44
    • Goodhead, D.T.1
  • 85
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
    • K. Rothkamm and M. Löbrich, Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl. Acad. Sci. USA 100, 5057-5062 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Löbrich, M.2
  • 87
    • 13844294491 scopus 로고    scopus 로고
    • No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low dose-rate irradiation in human cells
    • K. Ishizaki, Y. Hayashi, H. Nakamura, Y. Yasui, K. Komatsu and A. Tachibana, No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low dose-rate irradiation in human cells. J. Radiat. Res. 45, 521-525 (2004).
    • (2004) J. Radiat. Res , vol.45 , pp. 521-525
    • Ishizaki, K.1    Hayashi, Y.2    Nakamura, H.3    Yasui, Y.4    Komatsu, K.5    Tachibana, A.6
  • 88
    • 4644336002 scopus 로고    scopus 로고
    • Dose and dose-rate effects of low-dose ionizing radiation on the activation of trp53 in immortalized murine cells
    • T. Sugihara, J. Magae, R. Wadhwa, S. C. Kaul, Y. Kawakami, T. Matsumoto and K. Tanaka, Dose and dose-rate effects of low-dose ionizing radiation on the activation of trp53 in immortalized murine cells. Radiat. Res. 162, 296-307 (2004).
    • (2004) Radiat. Res , vol.162 , pp. 296-307
    • Sugihara, T.1    Magae, J.2    Wadhwa, R.3    Kaul, S.C.4    Kawakami, Y.5    Matsumoto, T.6    Tanaka, K.7
  • 89
    • 0031900748 scopus 로고    scopus 로고
    • Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines
    • E. Dikomey, J. Dahm-Daphi, I. Brammer, R. Martensen and B. Kaina, Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines. Int. J. Radiat. Biol. 73, 269-278 (1998).
    • (1998) Int. J. Radiat. Biol , vol.73 , pp. 269-278
    • Dikomey, E.1    Dahm-Daphi, J.2    Brammer, I.3    Martensen, R.4    Kaina, B.5
  • 90
    • 0034129412 scopus 로고    scopus 로고
    • Relationship between cellular radiosensitivity and non-repaired double-strand breaks studied for different growth states, dose rates and plating conditions in a normal human fibroblast line
    • E. Dikomey and I. Brammer, Relationship between cellular radiosensitivity and non-repaired double-strand breaks studied for different growth states, dose rates and plating conditions in a normal human fibroblast line. Int. J. Radiat. Biol. 76, 773-781 (2000).
    • (2000) Int. J. Radiat. Biol , vol.76 , pp. 773-781
    • Dikomey, E.1    Brammer, I.2
  • 91
    • 0035093737 scopus 로고    scopus 로고
    • signaling, repair and the cancer connection
    • DNA double-strand breaks
    • K. K. Khanna and S. P. Jackson, DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27, 247-254 (2001).
    • (2001) Nat. Genet , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 92
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the double-stranded break connection
    • D. C. van Gent, J. H. Hoeijmakers and R. Kanaar, Chromosomal stability and the double-stranded break connection. Nat. Rev. Genet. 2, 196-206 (2001).
    • (2001) Nat. Rev. Genet , vol.2 , pp. 196-206
    • van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 93
    • 0034624963 scopus 로고    scopus 로고
    • Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates
    • M. M. Vilenchik and A. G. Knudson, Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates. Proc. Natl. Acad. Sci. USA 97, 5381-5386 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5381-5386
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 94
    • 33845232990 scopus 로고    scopus 로고
    • Radiation dose-rate effects, endogenous DNA damage and signaling resonance
    • M. M. Vilenchik and A. G. Knudson, Radiation dose-rate effects, endogenous DNA damage and signaling resonance. Proc. Natl. Acad. Sci. USA 103, 17874-17879 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17874-17879
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 95
    • 0028827582 scopus 로고
    • Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines
    • C-Y. Li, H. Nagasawa, W. K. Dahlberg and J. B. Little, Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines. Oncogene 11, 1885-1892 (1995).
    • (1995) Oncogene , vol.11 , pp. 1885-1892
    • Li, C.-Y.1    Nagasawa, H.2    Dahlberg, W.K.3    Little, J.B.4


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