Evidence of DNA repair/processing defects in cultured skin fibroblasts from breast cancer patients

Cancer Research

Volumn 61, Issue 9, 2001, Pages 3627-3631

  Hannan, M A ^a   Siddiqui, Y ^a   Rostom, A ^a   Al Ahdal, M N ^a   Chaudhary, M A ^a   Kunhi, M ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; ARTICLE; ATAXIA TELANGIECTASIA; BREAST CANCER; CANCER PATIENT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA REPAIR; DNA SYNTHESIS INHIBITION; FEMALE; GAMMA RADIATION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC STABILITY; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIATION DOSE; SKIN FIBROBLAST;

ADULT; AGED; ATAXIA TELANGIECTASIA; BREAST NEOPLASMS; CELL SURVIVAL; CHILD; CHILD, PRESCHOOL; DNA REPAIR; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROBLASTS; HUMANS; MALE; MIDDLE AGED; RADIATION TOLERANCE; SKIN; TUMOR STEM CELL ASSAY;

EID: 0035328461     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Xeroderma pigmentosum, Cockayne syndrome and ataxia-telangiectasia: Disorders relating DNA repair to carcinogenesis
2. Cancer-prone hereditary diseases with DNA processing abnormalities
3. Human cancer syndromes: Clues to the origin and nature of cancer
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13. Analysis by alkaline comet assay of patients with severe reactions to radiotherapy: Defective rejoining of radioinduced DNA strand breaks in lymphocytes of breast cancer patients
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16. Statistical methods for in-vitro cell survival assays
17. Postirradiation DNA synthesis inhibition and G2 phase delay in radiosensitive body cells from non-Hodgkin's lymphoma patients: An indication of cell cycle defects
18. Enhanced reactivation and enhanced mutagenesis of herpes simplex virus in normal and xeroderma pigmentosum cells
19. Impaired DNA repair capability in skin fibroblasts from various hereditary cancer-prone syndromes
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21. Rare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity
22. The DNA damage response: Putting checkpoints in perspective