Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 370, Issue 1, 2004, Pages 54-63

  Jahnichen S ^a   Radtke, O A ^a   Pertz, H H ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

5 HT receptors; Guinea pig; Iliac artery; Migraine; Serotonin; Triptans; Vasoconstriction

Indexed keywords

5 CARBAMOYLTRYPTAMINE; ALMOTRIPTAN; ELETRIPTAN; FROVATRIPTAN; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; NARATRIPTAN; RIZATRIPTAN; SEROTONIN; SEROTONIN 1B AGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D AGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN 1D RECEPTOR; SUMATRIPTAN SUCCINATE; ZOLMITRIPTAN; 5-CARBOXAMIDOTRYPTAMINE; BENZAMIDE DERIVATIVE; CARBAZOLE DERIVATIVE; DRUG DERIVATIVE; INDOLE DERIVATIVE; KETANSERIN; MESSENGER RNA; N (3 (2 DIMETHYLAMINO)ETHOXY 4 METHOXYPHENYL) 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) (1,1' BIPHENYL) 4 CARBOXAMIDE; N-(3-(2-DIMETHYLAMINO)ETHOXY-4-METHOXYPHENYL)-2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)-(1,1'-BIPHENYL)-4-CARBOXAMIDE; OXADIAZOLE DERIVATIVE; OXAZOLIDINONE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; PROSTAGLANDIN F2 ALPHA; PYRROLIDINE DERIVATIVE; SUMATRIPTAN; TRIAZOLE DERIVATIVE; TRYPTAMINE DERIVATIVE;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GUINEA PIG; ILIAC ARTERY; MALE; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; BRAIN; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG SCREENING; FORECASTING; GENETICS; METABOLISM; METHODOLOGY; MUSCLE CONTRACTION; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE; VASCULAR ENDOTHELIUM;

ANIMALS; BENZAMIDES; BRAIN; CARBAZOLES; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENDOTHELIUM, VASCULAR; FEMALE; FORECASTING; GUINEA PIGS; ILIAC ARTERY; INDOLES; KETANSERIN; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OXADIAZOLES; OXAZOLIDINONES; PIPERAZINES; PIPERIDINES; PYRROLIDINES; RECEPTOR, SEROTONIN, 5-HT1B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEROTONIN; SUMATRIPTAN; TRIAZOLES; TRYPTAMINES;

EID: 4344702555     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. 1D receptors in sumatriptan mediated vasocontractile response in rabbit common carotid artery. Br J Pharmacol 136:177-182
2. 1D receptor. Br J Pharmacol 131:949-957
3. 1F receptor. Eur J Pharmacol 436:23-33
4. 1B receptor-mediated contraction of rabbit saphenous vein and basilar artery: role of vascular endothelium. J Pharmacol Exp Ther 309:825-832
5. Bou J, Gras J, Cortijo J, Morcillo EJ, Llenas J, Palacios JM (2001) Vascular effects of the new anti-migraine agent almotriptan on human cranial and peripheral arteries. Cephalalgia 21:804-812
6. Bouchelet I, Cohen Z, Case B, Seguela P, Hamel E (1996) Differential expression of sumatriptan-sensitive 5-hydroxytryptamine receptors in human trigeminal ganglia and cerebral blood vessels. Mol Pharmacol 50:219-223
7. 1F receptor agonists in human and bovine cerebral arteries: similarity with human coronary artery. Br J Pharmacol 129:501-508
8. 1D receptors. In: Olesen J, Moskowitz, MA (eds) Experimental headache models, vol 5. Lippincott-Raven, Philadelphia, pp 125-134
9. Chomczynski P, Sacchi N (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
10. 1-like receptor in rabbit renal artery. Eur J Pharmacol 231:469-472
11. 1-like receptors revealed by precontraction of rabbit isolated mesenteric artery. Br J Pharmacol 114:309-314
12. Cohen ML, Schenck K (1999) 5-Hydroxytryptamine(1F) receptors do not participate in vasoconstriction: lack of vasoconstriction to LY344864, a selective serotonin(1F) receptor agonist in rabbit saphenous vein. J Pharmacol Exp Ther 290:935-939
13. 1B/1D agonist frovatriptan. Headache 42 [Suppl 2]:S47-S53
14. 1D receptors in the sumatriptan-induced constriction of porcine carotid arteriovenous anastomoses. Br J Pharmacol 127:405-412
15. Furchgott RF (1972) The classification of adrenoceptors (adrenergic receptors). An evaluation from the standpoint of receptor theory. In: Blaschko H, Muscholl E (eds) Catecholamines, handbook of experimental pharmacology, vol 33. Springer, Berlin Heidelberg New York, pp 283-335
16. Goadsby PJ (2000) The pharmacology of headache. Progr Neurobiol 62:509-525
17. 1B/1D receptor-mediated contraction of the rabbit isolated renal artery. Br J Pharmacol 130:835-842
18. Humphrey PPA, Goadsby PJ (1994) Controversies in headache. The mode of action of sumatriptan is vascular? A debate. Cephalalgia 14:401-410
19. 2 receptor subtypes in human coronary arteries. Cardiovasc Res 41:267-274
20. 1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs. Neuroreport 8:2237-2240
21. 1B-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new antimigraine drugs. Cephalalgia 17:833-842
22. 1B- receptors. Br J Clin Pharmacol 46:577-582
23. MaassenVanDenBrink A, Reekers M, Bax WA, Ferrari MD, Saxena PR (1998) Coronary side-effect potential of current and prospective antimigraine drugs. Circulation 98:25-30
24. MaassenVanDenBrink A, van den Broek RWM, de Vries R, Bogers AJJC, Avezaat CJ, Saxena PR (2000) Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels. Neurology 55:1524-1530
25. 1 receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: influences of vascular endothelium and tone. Pulm Pharmacol 7:65-72
26. 1B receptor. Br J Pharmacol 128:730-734
27. Moskowitz MA, Cutrer FM (1993) Sumatriptan: a receptor-targeted treatment of migraine. Annu Rev Med 44:145-154
28. 1B-like receptors of rabbit ear artery. J Pharmacol Exp Ther 283:653-660
29. 1B/1D-mediated contraction in pulmonary arteries. Br J Pharmacol 138:795-800
30. 1B receptors in human cerebral arteries: pharmacological characterization and localization with immunocytochemistry. Br J Pharmacol 128:1133-1140
31. Nilsson T, Longmore J, Shaw D, Pantev E, Bard JA, Branchek T, Edvinsson L (1999b) Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques. Eur J Pharmacol 372:49-56
32. 1B/1D-receptor ligand frovatriptan in human isolated basilar and coronary arteries. J Cardiovasc Pharmacol 32:220-224
33. Pauwels PJ, John GW (1999) Present and future of 5-HT receptor agonists as antimigraine drugs. Clin Neuropharmacol 22:123-136
34. 1B receptor. Br J Pharmacol 123:51-62
35. 2 receptors. Naunyn-Schmiedebergs Arch Pharmacol 348:558-565
36. 1D receptors. Naunyn-Schmiedebergs Arch Pharmacol 356:312-320
37. 1F receptor activation. Br J Clin Pharmacol 47:75-82
38. 1B-receptors and vascular reactivity in human isolated blood vessels: assessment of the potential craniovascular selectivity of sumatriptan. Br J Clin Pharmacol 53:266-274
39. 1Dα serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug development. Proc Natl Acad Sci USA 91:3666-3669
40. 1-like receptors mediate 5-hydroxytryptamine-induced contraction of guinea-pig isolated iliac artery. Br J Pharmacol 102:386-390
41. 1-like receptors: a time to bid goodbye. Trends Pharmacol Sci 19:311-316
42. 1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn-Schmiedebergs Arch Pharmacol 356:321-327
43. 1-like receptor mediating contraction of guinea-pig iliac artery. Eur J Pharmacol 219:295-301
44. 1D receptor antagonist. Behav Brain Res 73:157-161
45. 2A "silent" receptors in rabbit ear artery. J Pharmacol Exp Ther 289:354-360
46. Tfelt-Hansen P, De Vries P, Saxena PR (2000) Triptans in migraine. A comparative review of pharmacology, pharmacokinetics and efficacy. Drugs 60:1259-1287
47. Ullmer C, Schmuck K, Kalkman HO, Lübbert H (1995) Expression of serotonin receptor mRNAs in blood vessels. FEBS Lett 370:215-221
48. 1D receptor agonists in the rabbit isolated saphenous vein. Br J Pharmacol 119:35-42
49. Van den Broek RWM, MaassenVanDenBrink A, de Vries R, Bogers AJJC, Stegmann APA, Avezaat CE, Saxena PR (2000) Pharmacological analysis of contractile effects of eletriptan and sumatriptan on human isolated blood vessels. Eur J Pharmacol 407:165-173
50. 1D receptor antagonists and in situ hybridization. Cephalalgia 22:83-93
51. Van Rossum JM (1963) Cumulative dose-response curves. II. Techniques for the making of dose-response curves in isolated organs and the evaluation of drug parameters. Arch Int Pharmacodyn 143:299-330
52. 1B receptor-mediated contractions in human temporal artery: evidence from selective antagonists and 5-HT receptor mRNA expression. Br J Pharmacol 124:1345-1354
53. Villalón C, Centurion D, De Vries P, Saxena PR (2002) An introduction to migraine: from ancient to functional pharmacology and antimigraine therapy. Proc West Pharmacol Soc 45:199-210
54. Waeber C, Moskowitz MA (2003) Therapeutic implications of central and peripheral neurologic mechanisms in migraine. Neurology 61 [Suppl 4]:S9-S20
55. 7 receptors. Neurotransmissions 15:3-15
56. 1B receptors. Br J Pharmacol 120:153-159
57. Yildiz O, Tuncer M (1995a) Amplification of responses to sumatriptan by various agonists in rabbit isolated iliac artery. J Cardiovasc Pharmacol 25:508-510
58. 2A receptors mediate 5-hydroxytryptamine-induced contraction of rabbit isolated mesenteric artery. Naunyn-Schmiedebergs Arch Pharmacol 352:127-131
59. 1D receptors. Neuropharmacology 36:513-524