Regulation of working memory by dopamine D4 receptor in rats

Neuropsychopharmacology

Volumn 29, Issue 9, 2004, Pages 1648-1655

  Zhang, Kehong ^a,b,c   Grady, Christopher J ^a,b   Tsapakis, Evangelia M ^a,b   Andersen, Susan L ^a,b   Tarazi, Frank I ^a,b   Baldessarini, Ross J ^a,b  

^a Mailman Research Center   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MCLEAN HOSPITAL   (United States)

Author keywords

Cognition; D4 receptor; Delayed alternation; Dopamine; L 745,870; Working memory

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; DOPAMINE 4 RECEPTOR; DOPAMINE D4 RECEPTOR ANTAGONIST; DOPAMINE RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; HYPOTHESIS; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TASK PERFORMANCE; WORKING MEMORY;

ANIMALS; ATTENTION; CONDITIONING, OPERANT; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMORY, SHORT-TERM; PSYCHOMOTOR PERFORMANCE; PYRIDINES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4;

EID: 4344701491     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300491     Document Type: Article

References (60)

1. Aggleton JP, Hunt PR, Rawlins JNP (1986). The effects of hippocampal lesions upon spatial and non-spatial tests of working memory. Behav Brain Res 19: 133-146.
2. 4 dopamine receptor protein in the CNS using anti-receptor antisera. Brain Res 752: 26-34.
3. 1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology 116: 143-151.
4. Arnsten AFT, Goldman-Rakic PS (1998). Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch Gen Psychiatry 55: 362-368.
5. 4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys. Neuropsychopharmacology 4: 405-410.
6. Aultman JM, Moghaddam B (2001). Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task. Psychopharmacology 15: 353-364.
7. Baddeley AD (1986). Working Memory. Claredon: Oxford.
8. Battig K, Rosvold HE, Mishkin M (1960). Comparison of the effects of frontal and caudate lesions on delayed response and alternation in monkeys. J Comp Physiol Psychol 53: 400-404.
9. Brito GNO, Thomas GJ (1981). T-maze alternation, response patterning, and septo-hippocampal circuitry in rats. Behav Brain Res 3: 319-340.
10. 4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. J Neural Transm 105: 749-767.
11. Brozoski TJ, Brown RM, Rosvold HE, Goldman PS (1979). Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205: 929-932.
12. Bubser M, Schmidt WJ (1990). 6-Hydroxydopamine lesion of the rat prefrontal cortex increases locomotor activity, impairs acquisition of delayed alternation tasks, but does not affect uninterrupted tasks in the radial maze. Behav Brain Res 37: 157-168.
13. Bushnell PJ, Levin ED (1993). Effects of dopaminergic drugs on working and reference memory in rats. Pharmacol Biochem Behav 45: 765-776.
14. 1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys. J Pharmacol Exp Ther 283: 183-189.
15. 1 receptor stimulation. Science 287: 2020-2022.
16. Constantinidis C, Williams GV, Goldman-Rakic PS (2002). A role for inhibition in shaping the temporal flow of information in prefrontal cortex. Nat Neurosci 5: 175-180.
17. 4 antagonist sonepipirazole in schizophrenia: a placebo-controlled trial. Biol Psychiatry 55: 445-451.
18. Davids E, Zhang K, Baldessarini RJ (2002). Stereoselective effects of methylphenidate on hyperactivity in juvenile rats induced by neonatal 6-hydroxydopamine lesioning. Psychopharmacology 160: 92-98.
19. Dember WN, Fowler H (1958). Spontaneous alternation behavior. Psychol Bull 55: 412-428.
20. Denney CB, Rapport MD (2001). Cognitive pharmacology of stimulants in children with ADHD. In: Solanto MV, Arnsten AFT, Castellanos FX (eds). Stimulant Drugs and ADHD. Oxford University Press: New York. pp 283-302.
21. Didriksen M (1995). Effects of antipsychotics on cognitive behaviour in rats using the delayed non-match to position paradigm. Eur J Pharmacol 281: 241-250.
22. 4 receptor gene and attention deficit hyperactivity disorder. Am J Psychiatry 158: 1052-1057.
23. Freedman M, Oscar-Berman M (1986). Bilateral frontal lobe disease and selective delayed response deficits in humans. Behav Neurosci 100: 337-342.
24. Goldman PS, Rosvold HE, Vest B, Galkin TW (1971). Analysis of the delayed-alternation deficit produced by dorsolateral prefrontal lesions in the rhesus monkey. J Comp Physiol Psychol 77: 212-220.
25. Goldman-Rakic PS (2001). Working memory dysfunction in schizophrenia. In: Salloway SP, Malloy PF, Duffy JD (eds). The Frontal Lobes and Neuropsychiatric Illness. American Psychiatric Publishing: Washington, DC. pp 71-82.
26. 4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology 142: 78-84.
27. Kolb B, Nonneman AJ, Singh RK (1974). Double dissociation of spatial impairments and perseveration following selective prefrontal lesions in rats. J Comp Physiol Psychol 87: 772-780.
28. 4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. Arch Gen Psychiatry 54: 567-572.
29. 4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder. Mol Psychiatry 1: 128-131.
30. 4 receptor. J Neurochem 68: 804-812.
31. Larsen JK, Divac I (1978). Selective ablations within the prefrontal cortex of the rat and performance of delayed alternation. Physiol Psychol 6: 15-17.
32. 4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition. Psychopharmacology 135: 194-200.
33. Mattay VS, Callicott JH, Bertolino A, Heaton I, Frank JA, Coppola R et al (2000). Effects of dextroamphetamine on cognitive performance and cortical activation. Neuroimage 12: 268-275.
34. Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF et al (2003). Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA 100: 6186-6191.
35. 4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]-piperazin-1-yl)methyl-1H-pyrrolo[2,3b]pyridine) and raclopride. J Pharmacol Exp Ther 287: 167-186.
36. Mizoguchi K, Yuzurihara M, Ishige A, Sasaki H, Chui D, Tabira T (2000). Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J Neurosci 20: 1568-1574.
37. 4 receptors in GABAergic neurons of the primate brain. Nature 381: 245-248.
38. Murphy BL, Arnsten ATF, Goldman-Rakic PS, Roth RH (1996). Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Pro Natl Acad Sci USA 93: 1325-1329.
39. 4 receptor: one decade of research. Eur J Pharmacol 405: 303-327.
40. 4 receptor. J Pharmacol Exp Ther 283: 636-647.
41. Pennington BF, Ozonoff S (1996). Executive functions and developmental psychopathology. J Child Psychol Psychiat 37: 51-87.
42. Pisa M (1981). Amnesia for discrete events in rats with fornicotomies: effects of interference on spatial alternation performance. J Comp Physiol Psychol 95: 924-942.
43. Rao SG, Williams GV, Goldman-Rakic PS (1999). Isodirectional tuning of adjacent interneurons and pyramidal cells during working memory: evidence for microcolumnar organization in PFC. J Neurophysiol 81: 1903-1916.
44. 4 receptor-deficient mice display cortical hyperexcitability. J Neurosci 21: 3756-3763.
45. 4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell 90: 991-1001.
46. 1 dopamine receptors in prefrontal cortex: involvement in working memory. Science 251: 947-950.
47. 1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task. J Neurophysiol 71: 515-528.
48. Simon H (1981). Dopaminergic A10 neurons and frontal system. J Physiol 77: 81-95.
49. Stam CJ, de Bruin JP, van Haelst AM, van der Gugten J, Kalsbeek A (1989). Influence of the mesocortical dopaminergic system on activity, food hoarding, social-agonistic behavior, and spatial delayed alternation in male rats. Behav Neurosci 103: 24-35.
50. 4 receptor localization in the rat nucleus accumbens. Synapse 36: 222-232.
51. 4 receptors: significance for molecular psychiatry at the millennium. Mol Psychiatry 4: 529-538.
52. 4 receptor gene with high affinity for the antipsychotic clozapine. Nature 350: 614-619.
53. Verin M, Partoit A, Pillon B, Malapani C, Agid Y, Dubois B (1993). Delayed response tasks and prefrontal lesions in man - evidence for self-generated patterns of behavior with poor environmental modulation. Neuropsychologia 31: 1279-1296.
54. Verma A, Moghaddam B (1996). NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine. J Neurosci 16: 373-379.
55. 4 receptor modulate GABAergic signaling in pyramidal neurons of prefrontal cortex. J Neurosci 22: 9185-9193.
56. 4 receptors in the rat brain- immunocytochemical study. J Physiol Pharmacol 51: 205-221.
57. 1 receptors in prefrontal cortex. Nature 37: 572-575.
58. 1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance. J Neurosci 17: 8528-8535.
59. 4 receptor-selective antagonists on motor hyperactivity in rats with neonatal 6-hydroxydopamine lesions. Psychopharmacology 161: 100-106.
60. 4 receptors in motor hyperactivity induced by neonatal 6-hydroxydopamine lesions in rats. Neuropsychopharmacology 25: 624-632.