-
1
-
-
0036157392
-
Cancer statistics, 2002
-
Jemal A., Thomas A., Murray T., Thun M. Cancer statistics, 2002. CA Cancer J Clin. 52:2002;23-47
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 23-47
-
-
Jemal, A.1
Thomas, A.2
Murray, T.3
Thun, M.4
-
2
-
-
0033572883
-
The American College of Surgeons Commission on Cancer and the American Cancer Society. The National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia
-
Diehl L.F., Karnell L.H., Menck H.R. The American College of Surgeons Commission on Cancer and the American Cancer Society. The National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia. Cancer. 86:1999;2684-2692
-
(1999)
Cancer
, vol.86
, pp. 2684-2692
-
-
Diehl, L.F.1
Karnell, L.H.2
Menck, H.R.3
-
3
-
-
0029981025
-
National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
-
Cheson B.D., Bennett J.M., Grever M., Kay N., Keating M.J., O'Brien S., et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 87:1996;4990-4997
-
(1996)
Blood
, vol.87
, pp. 4990-4997
-
-
Cheson, B.D.1
Bennett, J.M.2
Grever, M.3
Kay, N.4
Keating, M.J.5
O'Brien, S.6
-
4
-
-
0034667624
-
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
-
Burger J.A., Tsukada N., Burger M., Zvaifler N.J., Dell'Aquila M., Kipps T.J. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood. 96:2000;2655-2663
-
(2000)
Blood
, vol.96
, pp. 2655-2663
-
-
Burger, J.A.1
Tsukada, N.2
Burger, M.3
Zvaifler, N.J.4
Dell'Aquila, M.5
Kipps, T.J.6
-
5
-
-
0034523170
-
Update on the biology of chronic lymphocytic leukemia
-
Bannerji R., Byrd J.C. Update on the biology of chronic lymphocytic leukemia. Curr Opin Oncol. 12:2000;22-29
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 22-29
-
-
Bannerji, R.1
Byrd, J.C.2
-
6
-
-
0017751562
-
A clinical staging system for chronic lymphocytic leukemia: Prognostic significance
-
Binet J.L., Lepoprier M., Dighiero G., Charron D., D'Athis P., Vaugier G., et al. A clinical staging system for chronic lymphocytic leukemia: prognostic significance. Cancer. 40:1977;855-864
-
(1977)
Cancer
, vol.40
, pp. 855-864
-
-
Binet, J.L.1
Lepoprier, M.2
Dighiero, G.3
Charron, D.4
D'Athis, P.5
Vaugier, G.6
-
7
-
-
0016740933
-
Clinical staging of chronic lymphocytic leukemia
-
Rai K.R., Sawitsky A., Cronkite E.P., Chanana A.D., Levy R.N., Pasternack B.S. Clinical staging of chronic lymphocytic leukemia. Blood. 46:1975;219-234
-
(1975)
Blood
, vol.46
, pp. 219-234
-
-
Rai, K.R.1
Sawitsky, A.2
Cronkite, E.P.3
Chanana, A.D.4
Levy, R.N.5
Pasternack, B.S.6
-
8
-
-
0024319910
-
Fludarabine: A new agent with major activity against chronic lymphocytic leukemia
-
Keating M.J., Kantarjian H., Talpaz M., Redman J., Koller C., Barlogie B., et al. Fludarabine: a new agent with major activity against chronic lymphocytic leukemia. Blood. 74:1989;19-25
-
(1989)
Blood
, vol.74
, pp. 19-25
-
-
Keating, M.J.1
Kantarjian, H.2
Talpaz, M.3
Redman, J.4
Koller, C.5
Barlogie, B.6
-
9
-
-
0024216099
-
Fludarabine monophosphate: A potentially useful agent in chronic lymphocytic leukemia
-
Grever M.R., Kopecky K.J., Coltman C.A., Files J.C., Greenberg B.R., Hutton J.J., et al. Fludarabine monophosphate: a potentially useful agent in chronic lymphocytic leukemia. Nouv Rev Fr Hematol. 30:1988;457-459
-
(1988)
Nouv Rev Fr Hematol
, vol.30
, pp. 457-459
-
-
Grever, M.R.1
Kopecky, K.J.2
Coltman, C.A.3
Files, J.C.4
Greenberg, B.R.5
Hutton, J.J.6
-
10
-
-
15844368449
-
Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL
-
Johnson S., Smith A.G., Loffler H., Osby E., Juliusson G., Emmerich B., et al. Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL. Lancet. 347:1996;1432-1438
-
(1996)
Lancet
, vol.347
, pp. 1432-1438
-
-
Johnson, S.1
Smith, A.G.2
Loffler, H.3
Osby, E.4
Juliusson, G.5
Emmerich, B.6
-
11
-
-
0035889147
-
Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
-
Leporrier M., Chevret S., Cazin B., Boudjerra N., Feugier P., Desablens B., et al. Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients. Blood. 98:2001;2319-2325
-
(2001)
Blood
, vol.98
, pp. 2319-2325
-
-
Leporrier, M.1
Chevret, S.2
Cazin, B.3
Boudjerra, N.4
Feugier, P.5
Desablens, B.6
-
12
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai K.R., Peterson B.L., Appelbaum F.R., Kolitz J., Elias L., Shepherd L., et al. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med. 343:2000;1750-1757
-
(2000)
N Engl J Med
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Appelbaum, F.R.3
Kolitz, J.4
Elias, L.5
Shepherd, L.6
-
13
-
-
0027168420
-
Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes
-
Bubien J.K., Zhou L.J., Bell P.D., Frizzell R.A., Tedder T.F. Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes. J Cell Biol. 121:1993;1121-1132
-
(1993)
J Cell Biol
, vol.121
, pp. 1121-1132
-
-
Bubien, J.K.1
Zhou, L.J.2
Bell, P.D.3
Frizzell, R.A.4
Tedder, T.F.5
-
14
-
-
0345196590
-
CD20 is physically and functionally coupled to MHC class II and CD40 on human B cell lines
-
Leveille C., Al-Daccak R., Mourad W. CD20 is physically and functionally coupled to MHC class II and CD40 on human B cell lines. Eur J Immunol. 29:1999;65-74
-
(1999)
Eur J Immunol
, vol.29
, pp. 65-74
-
-
Leveille, C.1
Al-Daccak, R.2
Mourad, W.3
-
15
-
-
79960971501
-
High levels of soluble CD20 (sCD20) in patients with non-Hodgkin's lymphoma (NHL): Correlation with clinical behavior and contrast with patients with Hodgkin's disease (HD)
-
Vose J.M., Giles F.J., Manshouri T., Bociek G., Bierman P.J., Armitage J.O., et al. High levels of soluble CD20 (sCD20) in patients with non-Hodgkin's lymphoma (NHL): correlation with clinical behavior and contrast with patients with Hodgkin's disease (HD). Blood. 98:2001;767a
-
(2001)
Blood
, vol.98
-
-
Vose, J.M.1
Giles, F.J.2
Manshouri, T.3
Bociek, G.4
Bierman, P.J.5
Armitage, J.O.6
-
16
-
-
0036182539
-
Emerging information on the use of rituximab in chronic lymphocytic leukemia
-
Keating M.J., O'Brien S., Albitar M. Emerging information on the use of rituximab in chronic lymphocytic leukemia. Semin Oncol. 29(Suppl 2):2002;70-74
-
(2002)
Semin Oncol
, vol.29
, Issue.SUPPL. 2
, pp. 70-74
-
-
Keating, M.J.1
O'Brien, S.2
Albitar, M.3
-
17
-
-
0038446696
-
Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance
-
Manshouri T., Do K.A., Wang X., Giles F.J., O'Brien S.M., Saffer H.L., et al. Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance. Blood. 101:2003;2507-2513
-
(2003)
Blood
, vol.101
, pp. 2507-2513
-
-
Manshouri, T.1
Do, K.A.2
Wang, X.3
Giles, F.J.4
O'Brien, S.M.5
Saffer, H.L.6
-
18
-
-
0346103809
-
Rituximab: Converging mechanisms of action in non-Hodgkin's lymphoma?
-
Eisenbeis C.F., Caligiuri M.A., Byrd J.C. Rituximab: converging mechanisms of action in non-Hodgkin's lymphoma? Clin Cancer Res. 9:2003;5810-5812
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5810-5812
-
-
Eisenbeis, C.F.1
Caligiuri, M.A.2
Byrd, J.C.3
-
19
-
-
0036464611
-
The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
-
Byrd J.C., Kitada S., Flinn I.W., Aron J.L., Pearson M., Lucas D., et al. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction. Blood. 99:2002;1038-1043
-
(2002)
Blood
, vol.99
, pp. 1038-1043
-
-
Byrd, J.C.1
Kitada, S.2
Flinn, I.W.3
Aron, J.L.4
Pearson, M.5
Lucas, D.6
-
20
-
-
0037082469
-
The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism
-
Pedersen I.M., Buhl A.M., Klausen P., Geisler C.H., Jurlander J. The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase- dependent mechanism. Blood. 99:2002;1314-1319
-
(2002)
Blood
, vol.99
, pp. 1314-1319
-
-
Pedersen, I.M.1
Buhl, A.M.2
Klausen, P.3
Geisler, C.H.4
Jurlander, J.5
-
21
-
-
0842264005
-
Fc gamma RIIIa and Fc gamma RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia
-
Farag S.S., Flinn I.W., Modali R., Lehman T.A., Young D., Byrd J.C. Fc gamma RIIIa and Fc gamma RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia. Blood. 103:2004;1472-1474
-
(2004)
Blood
, vol.103
, pp. 1472-1474
-
-
Farag, S.S.1
Flinn, I.W.2
Modali, R.3
Lehman, T.A.4
Young, D.5
Byrd, J.C.6
-
22
-
-
0038518572
-
Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: Relationship to in vivo rituximab resistance
-
Bannerji R., Kitada S., Flinn I.W., Pearson M., Young D., Reed J.C., et al. Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: relationship to in vivo rituximab resistance. J Clin Oncol. 21:2003;1466-1471
-
(2003)
J Clin Oncol
, vol.21
, pp. 1466-1471
-
-
Bannerji, R.1
Kitada, S.2
Flinn, I.W.3
Pearson, M.4
Young, D.5
Reed, J.C.6
-
23
-
-
0345337254
-
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
McLaughlin P., Grillo-Lopez A.J., Link B.K., Levy R., Czuczman M.S., Williams M.E., et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. J Clin Oncol. 16:1998;2825-2833
-
(1998)
J Clin Oncol
, vol.16
, pp. 2825-2833
-
-
McLaughlin, P.1
Grillo-Lopez, A.J.2
Link, B.K.3
Levy, R.4
Czuczman, M.S.5
Williams, M.E.6
-
24
-
-
0032931320
-
IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non-Hodgkin's lymphoma and lymphoproliferative disorders: Evaluation of response on 48 patients
-
Nguyen D.T., Amess J.A., Doughty H., Hendry L., Diamond L.W. IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non-Hodgkin's lymphoma and lymphoproliferative disorders: evaluation of response on 48 patients. Eur J Haematol. 62:1999;76-82
-
(1999)
Eur J Haematol
, vol.62
, pp. 76-82
-
-
Nguyen, D.T.1
Amess, J.A.2
Doughty, H.3
Hendry, L.4
Diamond, L.W.5
-
25
-
-
0033214207
-
Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8)
-
Winkler U., Jensen M., Manzke O., Schulz H., Diehl V., Engert A. Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8). Blood. 94:1999;2217-2224
-
(1999)
Blood
, vol.94
, pp. 2217-2224
-
-
Winkler, U.1
Jensen, M.2
Manzke, O.3
Schulz, H.4
Diehl, V.5
Engert, A.6
-
26
-
-
0035469851
-
Rituximab therapy of patients with B-cell chronic lymphocytic leukemia
-
Huhn D., von Schilling C., Wilhelm M., Ho A.D., Hallek M., Kuse R., et al. Group GCLLS Rituximab therapy of patients with B-cell chronic lymphocytic leukemia. Blood. 98:2001;1326-1331
-
(2001)
Blood
, vol.98
, pp. 1326-1331
-
-
Huhn, D.1
Von Schilling, C.2
Wilhelm, M.3
Ho, A.D.4
Hallek, M.5
Kuse, R.6
-
27
-
-
0036757311
-
Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: Results from a Nordic multicentre study
-
Itala M., Geisler C.H., Kimby E., Juvonen E., Tjonnfjord G., Karlsson K., et al. Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: results from a Nordic multicentre study. Eur J Haematol. 69:2002;129-134
-
(2002)
Eur J Haematol
, vol.69
, pp. 129-134
-
-
Itala, M.1
Geisler, C.H.2
Kimby, E.3
Juvonen, E.4
Tjonnfjord, G.5
Karlsson, K.6
-
28
-
-
0038811776
-
Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network
-
Hainsworth J.D., Litchy S., Barton J.H., Houston G.A., Hermann R.C., Bradof J.E., et al. Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: a phase II trial of the Minnie Pearl Cancer Research Network. J Clin Oncol. 21:2003;1746-1751
-
(2003)
J Clin Oncol
, vol.21
, pp. 1746-1751
-
-
Hainsworth, J.D.1
Litchy, S.2
Barton, J.H.3
Houston, G.A.4
Hermann, R.C.5
Bradof, J.E.6
-
29
-
-
79951658129
-
Single agent rituxan in early stage chronic lymphocytic leukemia (CLL)
-
Thomas D.A., O'Brien S., Giles F.J., Cortes J., Faderl S., Kantarjian H., et al. Single agent rituxan in early stage chronic lymphocytic leukemia (CLL). Blood. 98:2001;364a
-
(2001)
Blood
, vol.98
-
-
Thomas, D.A.1
O'Brien, S.2
Giles, F.J.3
Cortes, J.4
Faderl, S.5
Kantarjian, H.6
-
30
-
-
0031837813
-
Levels of expression of CD19 and CD20 in chronic B cell leukaemias
-
Ginaldi L., De Martinis M., Matutes E., Farahat N., Morilla R., Catovsky D. Levels of expression of CD19 and CD20 in chronic B cell leukaemias. J Clin Pathol. 51:1998;364-369
-
(1998)
J Clin Pathol
, vol.51
, pp. 364-369
-
-
Ginaldi, L.1
De Martinis, M.2
Matutes, E.3
Farahat, N.4
Morilla, R.5
Catovsky, D.6
-
31
-
-
0036125566
-
Level of CD20 expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia
-
Perz J., Topaly J., Fruehauf S., Hensel M., Ho A.D. Level of CD20 expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia. Leuk Lymphoma. 43:2002;149-151
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 149-151
-
-
Perz, J.1
Topaly, J.2
Fruehauf, S.3
Hensel, M.4
Ho, A.D.5
-
32
-
-
7844225540
-
Association of serum rituximab (IDEC-C2B8) concentration and anti-tumor response in the treatment of recurrent low-grade or follicular non-Hodgkin's lymphoma
-
Berinstein N.L., Grillo-Lopez A.J., White C.A., Bence-Bruckler I., Maloney D., Czuczman M.S., et al. Association of serum rituximab (IDEC-C2B8) concentration and anti-tumor response in the treatment of recurrent low-grade or follicular non-Hodgkin's lymphoma. Ann Oncol. 9:1998;995-1001
-
(1998)
Ann Oncol
, vol.9
, pp. 995-1001
-
-
Berinstein, N.L.1
Grillo-Lopez, A.J.2
White, C.A.3
Bence-Bruckler, I.4
Maloney, D.5
Czuczman, M.S.6
-
33
-
-
0034468409
-
High-dose rituximab therapy in chronic lymphocytic leukemia
-
Keating M.J., O'Brien S. High-dose rituximab therapy in chronic lymphocytic leukemia. Semin Oncol. 27(Suppl 12):2000;86-90
-
(2000)
Semin Oncol
, vol.27
, Issue.SUPPL. 12
, pp. 86-90
-
-
Keating, M.J.1
O'Brien, S.2
-
34
-
-
0035871441
-
Rituximab dose-escalation trial in chronic lymphocytic leukemia
-
O'Brien S.M., Kantarjian H., Thomas D.A., Giles F.J., Freireich E.J., Cortes J., et al. Rituximab dose-escalation trial in chronic lymphocytic leukemia. J Clin Oncol. 19:2001;2165-2170
-
(2001)
J Clin Oncol
, vol.19
, pp. 2165-2170
-
-
O'Brien, S.M.1
Kantarjian, H.2
Thomas, D.A.3
Giles, F.J.4
Freireich, E.J.5
Cortes, J.6
-
35
-
-
0035871445
-
Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
-
Byrd J.C., Murphy T., Howard R.S., Lucas M.S., Goodrich A., Park K., et al. Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol. 19:2001;2153-2164
-
(2001)
J Clin Oncol
, vol.19
, pp. 2153-2164
-
-
Byrd, J.C.1
Murphy, T.2
Howard, R.S.3
Lucas, M.S.4
Goodrich, A.5
Park, K.6
-
36
-
-
0033016566
-
Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance
-
Byrd J.C., Waselenko J.K., Maneatis T.J., Murphy T., Ward F.T., Monahan B.P., et al. Rituximab therapy in hematologic malignancy patients with circulating blood tumor cells: association with increased infusion-related side effects and rapid blood tumor clearance. J Clin Oncol. 17:1999;791-795
-
(1999)
J Clin Oncol
, vol.17
, pp. 791-795
-
-
Byrd, J.C.1
Waselenko, J.K.2
Maneatis, T.J.3
Murphy, T.4
Ward, F.T.5
Monahan, B.P.6
-
37
-
-
0031664666
-
Rapid tumor lysis in a patient with B-cell chronic lymphocytic leukemia and lymphocytosis treated with an anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab)
-
Jensen M., Winkler U., Manzke O., Diehl V., Engert A. Rapid tumor lysis in a patient with B-cell chronic lymphocytic leukemia and lymphocytosis treated with an anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab). Ann Hematol. 77:1998;89-91
-
(1998)
Ann Hematol
, vol.77
, pp. 89-91
-
-
Jensen, M.1
Winkler, U.2
Manzke, O.3
Diehl, V.4
Engert, A.5
-
38
-
-
0042236333
-
Rituximab herapy for CLL
-
Lin T.S. L.M., Byrd J.C. Rituximab herapy for CLL. Semin Oncol. 30(4):2003;483-492
-
(2003)
Semin Oncol
, vol.30
, Issue.4
, pp. 483-492
-
-
Lin, T.S.L.M.1
Byrd, J.C.2
-
39
-
-
0037220152
-
Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: Results from Cancer and Leukemia Group B 9712 (CALGB 9712)
-
Byrd J.C., Peterson B.L., Morrison V.A., Park K., Jacobson R., Hoke E., et al. Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: results from Cancer and Leukemia Group B 9712 (CALGB 9712). Blood. 101:2003;6-14
-
(2003)
Blood
, vol.101
, pp. 6-14
-
-
Byrd, J.C.1
Peterson, B.L.2
Morrison, V.A.3
Park, K.4
Jacobson, R.5
Hoke, E.6
-
40
-
-
0003228854
-
Combination chemo-antibody therapy with fludarabine (F), cyclophosphamide (C) and rituximab (R) achieves a high CR rate in previously untreated chronic lymphocytic leukemia (CLL)
-
Keating M.J., O'Brien S., Lerner S., Giles F.J., Andreeff M., Cortes J., et al. Combination chemo-antibody therapy with fludarabine (F), cyclophosphamide (C) and rituximab (R) achieves a high CR rate in previously untreated chronic lymphocytic leukemia (CLL). Blood. 96:2000;514a
-
(2000)
Blood
, vol.96
-
-
Keating, M.J.1
O'Brien, S.2
Lerner, S.3
Giles, F.J.4
Andreeff, M.5
Cortes, J.6
-
41
-
-
0036839469
-
Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia
-
Schulz H., Klein S.K., Rehwald U., Reiser M., Hinke A., Knauf W.U., et al. Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia. Blood. 100:2002;3115-3120
-
(2002)
Blood
, vol.100
, pp. 3115-3120
-
-
Schulz, H.1
Klein, S.K.2
Rehwald, U.3
Reiser, M.4
Hinke, A.5
Knauf, W.U.6
-
42
-
-
0036839469
-
Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia
-
Schulz H., Klein S.K., Rehwald U., Reiser M., Hinke A., Knauf W.U., et al. Group GCS Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia. Blood. 100:2002;3115-3120
-
(2002)
Blood
, vol.100
, pp. 3115-3120
-
-
Schulz, H.1
Klein, S.K.2
Rehwald, U.3
Reiser, M.4
Hinke, A.5
Knauf, W.U.6
-
43
-
-
14344252714
-
Chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) improves complete response (CR), remission duration and survival as initial therapy of chronic lymphocytic leukemia (CLL)
-
Keating M.J., O'Brien S., Lerner S., Wierda W., Kantarjian H. Chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) improves complete response (CR), remission duration and survival as initial therapy of chronic lymphocytic leukemia (CLL). J Clin Oncol. 22(14S):2004;573
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 S
, pp. 573
-
-
Keating, M.J.1
O'Brien, S.2
Lerner, S.3
Wierda, W.4
Kantarjian, H.5
-
44
-
-
0036165916
-
CD38 expression and secondary 17p deletion are important prognostic factors in chronic lymphocytic leukaemia
-
Chevallier P., Penther D., Avet-Loiseau H., Robillard N., Ifrah N., Mahe B., et al. CD38 expression and secondary 17p deletion are important prognostic factors in chronic lymphocytic leukaemia. Br J Haematol. 116:2002;142-150
-
(2002)
Br J Haematol
, vol.116
, pp. 142-150
-
-
Chevallier, P.1
Penther, D.2
Avet-Loiseau, H.3
Robillard, N.4
Ifrah, N.5
Mahe, B.6
-
45
-
-
0028987180
-
P53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias
-
Dohner H., Fischer K., Bentz M., Hansen K., Benner A., Cabot G., et al. p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias. Blood. 85:1995;1580-1589
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Dohner, H.1
Fischer, K.2
Bentz, M.3
Hansen, K.4
Benner, A.5
Cabot, G.6
-
46
-
-
0031791801
-
Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: A sequential study of karyotypic instability in 51 patients
-
Finn W.G., Kay N.E., Kroft S.H., Church S., Peterson L.C. Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: a sequential study of karyotypic instability in 51 patients. Am J Hematol. 59:1998;223-229
-
(1998)
Am J Hematol
, vol.59
, pp. 223-229
-
-
Finn, W.G.1
Kay, N.E.2
Kroft, S.H.3
Church, S.4
Peterson, L.C.5
-
47
-
-
0025077558
-
Correlation of chromosome abnormalities with laboratory features and clinical course in B-cell chronic lymphocytic leukaemia
-
Oscier D.G., Stevens J., Hamblin T.J., Pickering R.M., Lambert R., Fitchett M. Correlation of chromosome abnormalities with laboratory features and clinical course in B-cell chronic lymphocytic leukaemia. Br J Haematol. 76:1990;352-358
-
(1990)
Br J Haematol
, vol.76
, pp. 352-358
-
-
Oscier, D.G.1
Stevens, J.2
Hamblin, T.J.3
Pickering, R.M.4
Lambert, R.5
Fitchett, M.6
-
48
-
-
0035679122
-
Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia
-
Jelinek D.F., Tschumper R.C., Geyer S.M., Bone N.D., Dewald G.W., Hanson C.A., et al. Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia. Br J Haematol. 115:2001;854-861
-
(2001)
Br J Haematol
, vol.115
, pp. 854-861
-
-
Jelinek, D.F.1
Tschumper, R.C.2
Geyer, S.M.3
Bone, N.D.4
Dewald, G.W.5
Hanson, C.A.6
-
49
-
-
0027436745
-
P53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
-
el Rouby S., Thomas A., Costin D., Rosenberg C.R., Potmesil M., Silber R., et al. p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression. Blood. 82:1993;3452-3459
-
(1993)
Blood
, vol.82
, pp. 3452-3459
-
-
El Rouby, S.1
Thomas, A.2
Costin, D.3
Rosenberg, C.R.4
Potmesil, M.5
Silber, R.6
-
50
-
-
17744410949
-
P53 expression in B-cell chronic lymphocytic leukemia: A marker of disease progression and poor prognosis
-
Cordone I., Masi S., Mauro F.R., Soddu S., Morsilli O., Valentini T., et al. p53 expression in B-cell chronic lymphocytic leukemia: a marker of disease progression and poor prognosis. Blood. 91:1998;4342-4349
-
(1998)
Blood
, vol.91
, pp. 4342-4349
-
-
Cordone, I.1
Masi, S.2
Mauro, F.R.3
Soddu, S.4
Morsilli, O.5
Valentini, T.6
-
51
-
-
0028172868
-
P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E., Preudhomme C., Hecquet B., Vanrumbeke M., Quesnel B., Dervite I., et al. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood. 84:1994;3148-3157
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
Vanrumbeke, M.4
Quesnel, B.5
Dervite, I.6
-
52
-
-
0032079746
-
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: Correlations with in vitro and in vivo chemoresponses
-
Kitada S., Andersen J., Akar S., Zapata J.M., Takayama S., Krajewski S., et al. Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses. Blood. 91:1998;3379-3389
-
(1998)
Blood
, vol.91
, pp. 3379-3389
-
-
Kitada, S.1
Andersen, J.2
Akar, S.3
Zapata, J.M.4
Takayama, S.5
Krajewski, S.6
-
53
-
-
0035437138
-
P53 dysfunction in B-cell chronic lymphocytic leukemia: Inactivation of ATM as an alternative to TP53 mutation
-
Pettitt A.R., Sherrington P.D., Stewart G., Cawley J.C., Taylor A.M., Stankovic T. p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation. Blood. 98:2001;814-822
-
(2001)
Blood
, vol.98
, pp. 814-822
-
-
Pettitt, A.R.1
Sherrington, P.D.2
Stewart, G.3
Cawley, J.C.4
Taylor, A.M.5
Stankovic, T.6
-
54
-
-
0033513587
-
Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia
-
Stankovic T., Weber P., Stewart G., Bedenham T., Murray J., Byrd P.J., et al. Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia. Lancet. 353:1999;26-29
-
(1999)
Lancet
, vol.353
, pp. 26-29
-
-
Stankovic, T.1
Weber, P.2
Stewart, G.3
Bedenham, T.4
Murray, J.5
Byrd, P.J.6
-
55
-
-
0036096157
-
Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage
-
Stankovic T., Stewart G.S., Fegan C., Biggs P., Last J., Byrd P.J., et al. Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage. Blood. 99:2002;300-309
-
(2002)
Blood
, vol.99
, pp. 300-309
-
-
Stankovic, T.1
Stewart, G.S.2
Fegan, C.3
Biggs, P.4
Last, J.5
Byrd, P.J.6
-
56
-
-
0034614551
-
Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway
-
Genini D., Budihardjo I., Plunkett W., Wang X., Carrera C.J., Cottam H.B., et al. Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway. J Biol Chem. 275:2000;29-34
-
(2000)
J Biol Chem
, vol.275
, pp. 29-34
-
-
Genini, D.1
Budihardjo, I.2
Plunkett, W.3
Wang, X.4
Carrera, C.J.5
Cottam, H.B.6
-
57
-
-
0034669944
-
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
-
Genini D., Adachi S., Chao Q., Rose D.W., Carrera C.J., Cottam H.B., et al. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood. 96:2000;3537-3543
-
(2000)
Blood
, vol.96
, pp. 3537-3543
-
-
Genini, D.1
Adachi, S.2
Chao, Q.3
Rose, D.W.4
Carrera, C.J.5
Cottam, H.B.6
-
58
-
-
0037228952
-
Interphase cytogenetic abnormalities in chronic lymphocytic leukemia may predict response to rituximab
-
Byrd J., Smith L., Hackbarth M., Flinn I., Young D., Proffitt J., et al. Interphase cytogenetic abnormalities in chronic lymphocytic leukemia may predict response to rituximab. Cancer Res. 63:2003;36-38
-
(2003)
Cancer Res
, vol.63
, pp. 36-38
-
-
Byrd, J.1
Smith, L.2
Hackbarth, M.3
Flinn, I.4
Young, D.5
Proffitt, J.6
-
59
-
-
0034501632
-
Campath-1H monoclonal antibody therapy
-
Flynn J.M., Byrd J.C. Campath-1H monoclonal antibody therapy. Curr Opin Oncol. 12:2000;574-581
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 574-581
-
-
Flynn, J.M.1
Byrd, J.C.2
-
60
-
-
0020591822
-
Removal of T cells from bone marrow for transplantation: A monoclonal antilymphocyte antibody that fixes human complement
-
Hale G., Bright S., Chumbley G., Hoang T., Metcalf D., Munro A.J., et al. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood. 62:1983;873-882
-
(1983)
Blood
, vol.62
, pp. 873-882
-
-
Hale, G.1
Bright, S.2
Chumbley, G.3
Hoang, T.4
Metcalf, D.5
Munro, A.J.6
-
61
-
-
0024204319
-
Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H
-
Hale G., Dyer M.J., Clark M.R., Phillips J.M., Marcus R., Riechmann L., et al. Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H. Lancet. 2:1988;1394-1399
-
(1988)
Lancet
, vol.2
, pp. 1394-1399
-
-
Hale, G.1
Dyer, M.J.2
Clark, M.R.3
Phillips, J.M.4
Marcus, R.5
Riechmann, L.6
-
64
-
-
0031790767
-
Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells
-
Rowan W., Tite J., Topley P., Brett S.J. Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells. Immunology. 95:1998;427-436
-
(1998)
Immunology
, vol.95
, pp. 427-436
-
-
Rowan, W.1
Tite, J.2
Topley, P.3
Brett, S.J.4
-
65
-
-
0021813140
-
Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation
-
Hale G., Swirsky D., Waldmann H., Chan L.C. Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation. Br J Haematol. 60:1985;41-48
-
(1985)
Br J Haematol
, vol.60
, pp. 41-48
-
-
Hale, G.1
Swirsky, D.2
Waldmann, H.3
Chan, L.C.4
-
66
-
-
0028352208
-
Immunohistochemical analysis of CDw52 antigen expression in non-Hodgkin's lymphomas
-
Salisbury J.R., Rapson N.T., Codd J.D., Rogers M.V., Nethersell A.B. Immunohistochemical analysis of CDw52 antigen expression in non-Hodgkin's lymphomas. J Clin Pathol. 47:1994;313-317
-
(1994)
J Clin Pathol
, vol.47
, pp. 313-317
-
-
Salisbury, J.R.1
Rapson, N.T.2
Codd, J.D.3
Rogers, M.V.4
Nethersell, A.B.5
-
67
-
-
0031027623
-
Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia
-
Bowen A.L., Zomas A., Emmett E., Matutes E., Dyer M.J., Catovsky D. Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia. Br J Haematol. 96:1997;617-619
-
(1997)
Br J Haematol
, vol.96
, pp. 617-619
-
-
Bowen, A.L.1
Zomas, A.2
Emmett, E.3
Matutes, E.4
Dyer, M.J.5
Catovsky, D.6
-
68
-
-
4344630062
-
Multicenter study of Campath-1H in patients with chronic lymphocytic leukemia (B-CLL) refractory to fludarabine
-
Keating M.J., Byrd J.C., Rai K., Flinn I., Jain V., Binet L., et al. Group C-Hcs Multicenter study of Campath-1H in patients with chronic lymphocytic leukemia (B-CLL) refractory to fludarabine. Blood. 96:2000;722a
-
(2000)
Blood
, vol.96
-
-
Keating, M.J.1
Byrd, J.C.2
Rai, K.3
Flinn, I.4
Jain, V.5
Binet, L.6
-
69
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study
-
Keating M.J., Flinn I., Jain V., Binet J.-L., Hillmen P., Byrd J.C., et al. Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood. 99:2002;3554-3561
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
Binet, J.-L.4
Hillmen, P.5
Byrd, J.C.6
-
70
-
-
0029937765
-
Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia
-
Osterborg A., Fassas A.S., Anagnostopoulos A., Dyer M.J., Catovsky D., Mellstedt H. Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia. Br J Haematol. 93:1996;151-153
-
(1996)
Br J Haematol
, vol.93
, pp. 151-153
-
-
Osterborg, A.1
Fassas, A.S.2
Anagnostopoulos, A.3
Dyer, M.J.4
Catovsky, D.5
Mellstedt, H.6
-
71
-
-
0030897222
-
Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia: European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
-
Osterborg A., Dyer M.J., Bunjes D., Pangalis G.A., Bastion Y., Catovsky D., et al. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia: European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol. 15:1997;1567-1574
-
(1997)
J Clin Oncol
, vol.15
, pp. 1567-1574
-
-
Osterborg, A.1
Dyer, M.J.2
Bunjes, D.3
Pangalis, G.A.4
Bastion, Y.5
Catovsky, D.6
-
72
-
-
79960971484
-
Efficacy and safety of alemtuzumab (Campath-1H) in refractory B-CLL patients treated on a compassionate basis
-
Rai K.R., Coutre S., Rizzieri D., Gribben J.G., Flinn I., Rabinowe S., et al. Group CS Efficacy and safety of alemtuzumab (Campath-1H) in refractory B-CLL patients treated on a compassionate basis. Blood. 98:2001;365a
-
(2001)
Blood
, vol.98
-
-
Rai, K.R.1
Coutre, S.2
Rizzieri, D.3
Gribben, J.G.4
Flinn, I.5
Rabinowe, S.6
-
73
-
-
0036683449
-
Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
-
Lundin J., Kimby E., Bjorkholm M., Broliden P.A., Celsing F., Hjalmar V., et al. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood. 100:2002;768-773
-
(2002)
Blood
, vol.100
, pp. 768-773
-
-
Lundin, J.1
Kimby, E.2
Bjorkholm, M.3
Broliden, P.A.4
Celsing, F.5
Hjalmar, V.6
-
74
-
-
0030964964
-
In vivo 'purging' of residual disease in CLL with Campath-1H
-
Dyer M.J., Kelsey S.M., Mackay H.J., Emmett E., Thornton P., Hale G., et al. In vivo 'purging' of residual disease in CLL with Campath-1H. Br J Haematol. 97:1997;669-672
-
(1997)
Br J Haematol
, vol.97
, pp. 669-672
-
-
Dyer, M.J.1
Kelsey, S.M.2
MacKay, H.J.3
Emmett, E.4
Thornton, P.5
Hale, G.6
-
75
-
-
0036076178
-
Safety and efficacy of subcutaneous Campath-1H for treating residual disease in patients with chronic lymphocytic leukemia responding to fludarabine
-
Montillo M., Cafro A.M., Tedeschi A., Brando B., Oreste P., Veronese S., et al. Safety and efficacy of subcutaneous Campath-1H for treating residual disease in patients with chronic lymphocytic leukemia responding to fludarabine. Haematologica. 87:2002;695-700
-
(2002)
Haematologica
, vol.87
, pp. 695-700
-
-
Montillo, M.1
Cafro, A.M.2
Tedeschi, A.3
Brando, B.4
Oreste, P.5
Veronese, S.6
-
76
-
-
0037860441
-
A phase II trial of fludarabine followed by alemtuzumab (Campath-1H) in previously untreated chronic lymphocytic leukemia (CLL) Patients with Active Disease: Cancer and Leukemia Group B (CALGB) study 19901
-
Rai K.R., Peterson B., Larson R.A. A phase II trial of fludarabine followed by alemtuzumab (Campath-1H) in previously untreated chronic lymphocytic leukemia (CLL) Patients with Active Disease: Cancer and Leukemia Group B (CALGB) study 19901. Blood. 101:2002;205a
-
(2002)
Blood
, vol.101
-
-
Rai, K.R.1
Peterson, B.2
Larson, R.A.3
-
77
-
-
0344236261
-
Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia
-
O'Brien S., Kantarjan H.M., Thomas D.A., Cortes J., Giles F.J., Wierda W.G., et al. Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia. Cancer. 98(12):2003;2657-2663
-
(2003)
Cancer
, vol.98
, Issue.12
, pp. 2657-2663
-
-
O'Brien, S.1
Kantarjan, H.M.2
Thomas, D.A.3
Cortes, J.4
Giles, F.J.5
Wierda, W.G.6
-
78
-
-
2942540231
-
High efficacy but considerable toxicity of campath-1H consolidation therapy in CLL patients responding to fludarabine: Results of a randomized phase III trial
-
Wendtner C.M., Fingerle-Rowson G., Jaeger G., Campe H., Engert A., Doehner H., et al. High efficacy but considerable toxicity of campath-1H consolidation therapy in CLL patients responding to fludarabine: results of a randomized phase III trial. Proc Am Soc Clin Oncol. 2003
-
(2003)
Proc Am Soc Clin Oncol
-
-
Wendtner, C.M.1
Fingerle-Rowson, G.2
Jaeger, G.3
Campe, H.4
Engert, A.5
Doehner, H.6
-
79
-
-
0035075989
-
A phase II multicenter study of Campath-1H antibody in previously treated patients with nonbulky non-Hodgkin's lymphoma
-
Khorana A., Bunn P., McLaughlin P., Vose J., Stewart C., Czuczman M.S. A phase II multicenter study of Campath-1H antibody in previously treated patients with nonbulky non-Hodgkin's lymphoma. Leuk Lymphoma. 41:2001;77-87
-
(2001)
Leuk Lymphoma
, vol.41
, pp. 77-87
-
-
Khorana, A.1
Bunn, P.2
McLaughlin, P.3
Vose, J.4
Stewart, C.5
Czuczman, M.S.6
-
80
-
-
0030300084
-
Immunosuppressive toxicity of CAMPATH1H monoclonal antibody in the treatment of patients with recurrent low grade lymphoma
-
Tang S.C., Hewitt K., Reis M.D., Berinstein N.L. Immunosuppressive toxicity of CAMPATH1H monoclonal antibody in the treatment of patients with recurrent low grade lymphoma. Leuk Lymphoma. 24:1996;93-101
-
(1996)
Leuk Lymphoma
, vol.24
, pp. 93-101
-
-
Tang, S.C.1
Hewitt, K.2
Reis, M.D.3
Berinstein, N.L.4
-
81
-
-
0031757274
-
CAMPATH-1H monoclonal antibody in therapy for previously treated low-grade non-Hodgkin's lymphoma: A phase II multicenter study. European Study Group of CAMPATH-1H Treatment in Low-Grade Non-Hodgkin's Lymphoma
-
Lundin J., Osterborg A., Brittinger G., Crowther D., Dombret H., Engert A., et al. CAMPATH-1H monoclonal antibody in therapy for previously treated low-grade non-Hodgkin's lymphoma: a phase II multicenter study. European Study Group of CAMPATH-1H Treatment in Low-Grade Non-Hodgkin's Lymphoma. J Clin Oncol. 16:1998;3257-3263
-
(1998)
J Clin Oncol
, vol.16
, pp. 3257-3263
-
-
Lundin, J.1
Osterborg, A.2
Brittinger, G.3
Crowther, D.4
Dombret, H.5
Engert, A.6
-
82
-
-
0029666221
-
Repopulation of blood lymphocyte sub-populations in rheumatoid arthritis patients treated with the depleting humanized monoclonal antibody, CAMPATH-1H
-
Brett S., Baxter G., Cooper H., Johnston J.M., Tite J., Rapson N. Repopulation of blood lymphocyte sub-populations in rheumatoid arthritis patients treated with the depleting humanized monoclonal antibody, CAMPATH-1H. Immunology. 88:1996;13-19
-
(1996)
Immunology
, vol.88
, pp. 13-19
-
-
Brett, S.1
Baxter, G.2
Cooper, H.3
Johnston, J.M.4
Tite, J.5
Rapson, N.6
-
83
-
-
0029824828
-
Campath-1G impairs human natural killer (NK) cell-mediated cytotoxicity
-
Condiotti R., Nagler A. Campath-1G impairs human natural killer (NK) cell-mediated cytotoxicity. Bone Marrow Transplant. 18:1996;713-720
-
(1996)
Bone Marrow Transplant
, vol.18
, pp. 713-720
-
-
Condiotti, R.1
Nagler, A.2
-
84
-
-
0027853686
-
Effects of CAMPATH-1 antibodies on the functional activity of monocytes and polymorphonuclear neutrophils
-
Fabian I., Flidel O., Gadish M., Kletter Y., Slavin S., Nagler A. Effects of CAMPATH-1 antibodies on the functional activity of monocytes and polymorphonuclear neutrophils. Exp Hematol. 21:1993;1522-1527
-
(1993)
Exp Hematol
, vol.21
, pp. 1522-1527
-
-
Fabian, I.1
Flidel, O.2
Gadish, M.3
Kletter, Y.4
Slavin, S.5
Nagler, A.6
-
85
-
-
4344710500
-
Peripheral blood dendritic cells express CD52 and are depleted in vivo by treatment with Campath-1H
-
Buggins A.G.S., Mufti G.J., Fishlock K., Arno M., Hale G., Waldmann H., et al. Peripheral blood dendritic cells express CD52 and are depleted in vivo by treatment with Campath-1H. Blood. 98:2001;366a
-
(2001)
Blood
, vol.98
-
-
Buggins, A.G.S.1
Mufti, G.J.2
Fishlock, K.3
Arno, M.4
Hale, G.5
Waldmann, H.6
-
86
-
-
0032535279
-
Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection
-
Hale G., Zhang M.J., Bunjes D., Prentice H.G., Spence D., Horowitz M.M., et al. Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection. Blood. 92:1998;4581-4590
-
(1998)
Blood
, vol.92
, pp. 4581-4590
-
-
Hale, G.1
Zhang, M.J.2
Bunjes, D.3
Prentice, H.G.4
Spence, D.5
Horowitz, M.M.6
-
87
-
-
0033949148
-
CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells
-
Hale G., Jacobs P., Wood L., Fibbe W.E., Barge R., Novitzky N., et al. CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells. Bone Marrow Transplant. 26:2000;69-76
-
(2000)
Bone Marrow Transplant
, vol.26
, pp. 69-76
-
-
Hale, G.1
Jacobs, P.2
Wood, L.3
Fibbe, W.E.4
Barge, R.5
Novitzky, N.6
-
88
-
-
0005950282
-
Randomized trial of early versus delayed GM-CSF with Campath-1H: Preliminary feasibility and correlative biologic studies results
-
Flinn I.W., Sickler J., Lucas M., Buj V., Waymer S., Shinn C., et al. Randomized trial of early versus delayed GM-CSF with Campath-1H: preliminary feasibility and correlative biologic studies results. Blood. 96:2000;838a
-
(2000)
Blood
, vol.96
-
-
Flinn, I.W.1
Sickler, J.2
Lucas, M.3
Buj, V.4
Waymer, S.5
Shinn, C.6
-
89
-
-
0038351661
-
Filgrastim and alemtuzumab (Campath-1H) for refractory chronic lymphocytic leukemia: High frequency of cytomegalovirus disease and delayed neutropenia
-
Lin T.S., Flinn I.W., Lucas M.S., Sickler J., Moran M., Porcu P., et al. Filgrastim and alemtuzumab (Campath-1H) for refractory chronic lymphocytic leukemia: high frequency of cytomegalovirus disease and delayed neutropenia. Blood. 100:2002;802a
-
(2002)
Blood
, vol.100
-
-
Lin, T.S.1
Flinn, I.W.2
Lucas, M.S.3
Sickler, J.4
Moran, M.5
Porcu, P.6
-
90
-
-
0037085770
-
Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia
-
Kennedy B., Rawstron A., Carter C., Ryan M., Speed K., Lucas G., et al. Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia. Blood. 99:2002;2245-2247
-
(2002)
Blood
, vol.99
, pp. 2245-2247
-
-
Kennedy, B.1
Rawstron, A.2
Carter, C.3
Ryan, M.4
Speed, K.5
Lucas, G.6
-
91
-
-
79960970604
-
Phase I study of rituximab and Campath-1H in patients with relapsed or refractory chronic lymphocytic leukemia
-
Nabhan C., Tallman M.S., Riley M.B., Fitzpatrick J., Gordon L.I., Gartenhaus R., et al. Phase I study of rituximab and Campath-1H in patients with relapsed or refractory chronic lymphocytic leukemia. Blood. 98:2003;365a
-
(2003)
Blood
, vol.98
-
-
Nabhan, C.1
Tallman, M.S.2
Riley, M.B.3
Fitzpatrick, J.4
Gordon, L.I.5
Gartenhaus, R.6
-
92
-
-
0038724252
-
Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies
-
Faderl S., Thomas D.A., O'Brien S., Garcia-Manero G., Kantarjian H.M., Giles F.J., et al. Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies. Blood. 101:2003;3413-3415
-
(2003)
Blood
, vol.101
, pp. 3413-3415
-
-
Faderl, S.1
Thomas, D.A.2
O'Brien, S.3
Garcia-Manero, G.4
Kantarjian, H.M.5
Giles, F.J.6
-
93
-
-
0037103272
-
Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia
-
Lin K., Sherrington P.D., Dennis M., Matrai Z., Cawley J.C., Pettitt A.R. Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia. Blood. 100:2002;1404-1409
-
(2002)
Blood
, vol.100
, pp. 1404-1409
-
-
Lin, K.1
Sherrington, P.D.2
Dennis, M.3
Matrai, Z.4
Cawley, J.C.5
Pettitt, A.R.6
-
94
-
-
1242291417
-
Genomic aberrations, p53 abnormalities, and IgV mutation: Relationship to disease evolution, resistance to therapy, and clinical course of CLL
-
Stilgenbauer S. Genomic aberrations, p53 abnormalities, and IgV mutation: relationship to disease evolution, resistance to therapy, and clinical course of CLL. Leuk Lymphoma. 62(2):2000;76-82
-
(2000)
Leuk Lymphoma
, vol.62
, Issue.2
, pp. 76-82
-
-
Stilgenbauer, S.1
-
95
-
-
0037850927
-
Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy
-
Sturm I., Bosanquet A.G., Hermann S., Guner D., Dorken B., Daniel P.T. Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy. Cell Death Differ. 10:2003;477-484
-
(2003)
Cell Death Differ
, vol.10
, pp. 477-484
-
-
Sturm, I.1
Bosanquet, A.G.2
Hermann, S.3
Guner, D.4
Dorken, B.5
Daniel, P.T.6
-
96
-
-
0037228952
-
Interphase cytogenetic abnormalities in chronic lymphocytic leukemia may predict response to rituximab
-
Byrd J.C., Smith L., Hackbarth M.L., Flinn I.W., Young D., Proffitt J.H., et al. Interphase cytogenetic abnormalities in chronic lymphocytic leukemia may predict response to rituximab. Cancer Res. 63:2003;36-38
-
(2003)
Cancer Res
, vol.63
, pp. 36-38
-
-
Byrd, J.C.1
Smith, L.2
Hackbarth, M.L.3
Flinn, I.W.4
Young, D.5
Proffitt, J.H.6
-
97
-
-
0037043653
-
Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy
-
Stilgenbauer S., Dohner H. Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy. N Engl J Med. 347:2002;452-453
-
(2002)
N Engl J Med
, vol.347
, pp. 452-453
-
-
Stilgenbauer, S.1
Dohner, H.2
-
98
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski G., Heerema N.A., Flinn I.W., Smith L., Harbison J., Webb J., et al. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood. 103:2004;3278-3281
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, I.W.3
Smith, L.4
Harbison, J.5
Webb, J.6
|