Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity

Chemistry and Biology

Volumn 11, Issue 8, 2004, Pages 1071-1079

  Sandmann, Axel ^a,b   Sasse, Florenz ^a   Müller, Rolf ^a,b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; ISOLEUCINE; THIAZOLE DERIVATIVE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MULTIGENE FAMILY; MUTATION; MYXOCOCCALES; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF; SEQUENCE ALIGNMENT; TUMOR CELL LINE;

AMINO ACID MOTIFS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; ISOLEUCINE; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIGENE FAMILY; MUTATION; MYXOCOCCALES; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THIAZOLES;

ANGIOCOCCUS DISCIFORMIS; MYXOCOCCALES; TRANSPOSONS;

EID: 4344669553     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.05.014     Document Type: Article

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