Molecular determinants of differential pore blocking of kidney CLC-K chloride channels

EMBO Reports

Volumn 5, Issue 6, 2004, Pages 584-589

  Picollo, Alessandra ^a   Liantonio, Antonella ^a,b   Didonna, Maria Paola ^a,b   Elia, Laura ^a   Camerino, Diana Conte ^b   Pusch, Michael ^a  

^a CNR   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Block; CLC Ka; CLC Kb; DIDS; Mutations; Wild type

Indexed keywords

2 (4 CHLOROPHENOXY) 3 PHENYLPROPIONIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; AMINO ACID; BACTERIAL PROTEIN; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING SITE; DRUG MECHANISM; DRUG SENSITIVITY; DRUG TARGETING; HUMAN; KIDNEY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY;

2-METHYL-4-CHLOROPHENOXYACETIC ACID; 4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; AMINO ACID MOTIFS; ANION TRANSPORT PROTEINS; BINDING SITES; CHLORIDE CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE PROTEINS; PATCH-CLAMP TECHNIQUES; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY;

BACTERIA (MICROORGANISMS);

EID: 4344666270     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400169     Document Type: Article

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