메뉴 건너뛰기




Volumn 173, Issue 5, 2004, Pages 3073-3083

An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; PROTEIN KINASE C THETA; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT;

EID: 4344657752     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.5.3073     Document Type: Article
Times cited : (25)

References (60)
  • 1
    • 0034654574 scopus 로고    scopus 로고
    • Enhancing DNA immunization
    • Rodriguez, F., and J. L. Whitton. 2000. Enhancing DNA immunization. Virology 268:233.
    • (2000) Virology , vol.268 , pp. 233
    • Rodriguez, F.1    Whitton, J.L.2
  • 2
    • 0032971227 scopus 로고    scopus 로고
    • Degradation of cell proteins and the generation of MHC class I-presented peptides
    • Rock, K. L., and A. L. Goldberg. 1999. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu. Rev. Immunol. 17:739.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 739
    • Rock, K.L.1    Goldberg, A.L.2
  • 3
    • 0035399848 scopus 로고    scopus 로고
    • Not such a dismal science: The economics of protein synthesis, folding, degradation and antigen processing
    • Yewdell, J. W. 2001. Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing. Trends Cell Biol. 11:294.
    • (2001) Trends Cell Biol. , vol.11 , pp. 294
    • Yewdell, J.W.1
  • 4
    • 0028208970 scopus 로고
    • TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide
    • Bacik, I., J. H. Cox, R. Anderson, J. W. Yewdell, and J. R. Bennink. 1994. TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide. J. Immunol. 152:381.
    • (1994) J. Immunol. , vol.152 , pp. 381
    • Bacik, I.1    Cox, J.H.2    Anderson, R.3    Yewdell, J.W.4    Bennink, J.R.5
  • 7
    • 0030812840 scopus 로고    scopus 로고
    • DNA immunization: Ubiquitinization of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody formation
    • Rodriguez, F., J. Zhang, and J. L. Whitton. 1997. DNA immunization: ubiquitinization of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody formation. J. Virol. 71:8497.
    • (1997) J. Virol. , vol.71 , pp. 8497
    • Rodriguez, F.1    Zhang, J.2    Whitton, J.L.3
  • 8
    • 0032811821 scopus 로고    scopus 로고
    • Genetic live vaccines mimic the antigenicity but not pathogenicity of live viruses
    • Sykes, K. F., and S. A. Johnston. 1999. Genetic live vaccines mimic the antigenicity but not pathogenicity of live viruses. DNA Cell Biol. 18:521.
    • (1999) DNA Cell Biol. , vol.18 , pp. 521
    • Sykes, K.F.1    Johnston, S.A.2
  • 9
    • 0030977234 scopus 로고    scopus 로고
    • Targeting of HIV-1 antigens for rapid intracellular degradation enhances CTL recognition and the induction of de novo CTL responses in vivo following immunization
    • Tobery, T., and R. F. Siliciano. 1997. Targeting of HIV-1 antigens for rapid intracellular degradation enhances CTL recognition and the induction of de novo CTL responses in vivo following immunization. J. Exp. Med. 185:909.
    • (1997) J. Exp. Med. , vol.185 , pp. 909
    • Tobery, T.1    Siliciano, R.F.2
  • 10
    • 0024095276 scopus 로고
    • Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen
    • Townsend, A., J. Bastin, K. Gould, G. Brownlee, M. Andrew, B. Coupar, D. Boyle, S. Chan, and G. Smith. 1988. Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. J. Exp. Med. 168:1211.
    • (1988) J. Exp. Med. , vol.168 , pp. 1211
    • Townsend, A.1    Bastin, J.2    Gould, K.3    Brownlee, G.4    Andrew, M.5    Coupar, B.6    Boyle, D.7    Chan, S.8    Smith, G.9
  • 11
    • 0031573585 scopus 로고    scopus 로고
    • Deoxyribonucleic acid vaccines encoding antigens with rapid proteasome-dependent degradation are highly efficient inducers of cytolytic T lymphocytes
    • Wu, Y., and T. J. Kipps. 1997. Deoxyribonucleic acid vaccines encoding antigens with rapid proteasome-dependent degradation are highly efficient inducers of cytolytic T lymphocytes. J. Immunol. 159:6037.
    • (1997) J. Immunol. , vol.159 , pp. 6037
    • Wu, Y.1    Kipps, T.J.2
  • 12
    • 0037565206 scopus 로고    scopus 로고
    • Enhanced cellular immune response against SIV Gag induced by immunization with DNA vaccines expressing assembly and release-defective SIV Gag proteins
    • Bu, Z., L. Ye, R. W. Compans, and C. Yang. 2003. Enhanced cellular immune response against SIV Gag induced by immunization with DNA vaccines expressing assembly and release-defective SIV Gag proteins, Virology 309:272.
    • (2003) Virology , vol.309 , pp. 272
    • Bu, Z.1    Ye, L.2    Compans, R.W.3    Yang, C.4
  • 13
    • 0345318908 scopus 로고
    • Ubiquitin dependent and independent proteolytic pathways for MHC class I-restricted presentation of ovalbumin
    • Michalek, M. T., E. P. Grant, and K. L. Rock. 1994. Ubiquitin dependent and independent proteolytic pathways for MHC class I-restricted presentation of ovalbumin. FASEB J. 8:A747.
    • (1994) FASEB J. , vol.8
    • Michalek, M.T.1    Grant, E.P.2    Rock, K.L.3
  • 14
    • 0030240571 scopus 로고    scopus 로고
    • Generation of naturally processed peptide/MHC class I complexes is independent of the stability of endogenously synthesized precursors
    • Goth, S., V. Nguyen, and N. Shastri. 1996. Generation of naturally processed peptide/MHC class I complexes is independent of the stability of endogenously synthesized precursors. J. Immunol. 157:1894.
    • (1996) J. Immunol. , vol.157 , pp. 1894
    • Goth, S.1    Nguyen, V.2    Shastri, N.3
  • 16
    • 0032785706 scopus 로고    scopus 로고
    • Targeting of hepatitis C virus core protein for MHC I or MHC II presentation does not enhance induction of immune responses to DNA vaccination
    • Vidalin, O., E. Tanaka, U. Spengler, C. Trepo, and G. Inchauspe. 1999. Targeting of hepatitis C virus core protein for MHC I or MHC II presentation does not enhance induction of immune responses to DNA vaccination. DNA Cell Biol. 18:611.
    • (1999) DNA Cell Biol. , vol.18 , pp. 611
    • Vidalin, O.1    Tanaka, E.2    Spengler, U.3    Trepo, C.4    Inchauspe, G.5
  • 17
    • 0034162484 scopus 로고    scopus 로고
    • The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice
    • Bullock, T. N. J., T. A. Colella, and V. H. Engelhard. 2000. The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice. J. Immunol. 164:2354.
    • (2000) J. Immunol. , vol.164 , pp. 2354
    • Bullock, T.N.J.1    Colella, T.A.2    Engelhard, V.H.3
  • 18
    • 0033214423 scopus 로고    scopus 로고
    • The induction of virus-specific CTL as a function of increasing epitope expression: Responses rise steadily until excessively high levels of epitope are attained
    • Wherry, E. J., K. A. Puorro, A. Porgador, and L. C. Eisenlohr. 1999. The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. J. Immunol. 163:3735.
    • (1999) J. Immunol. , vol.163 , pp. 3735
    • Wherry, E.J.1    Puorro, K.A.2    Porgador, A.3    Eisenlohr, L.C.4
  • 21
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D. J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300:337.
    • (2003) Science , vol.300 , pp. 337
    • Shedlock, D.J.1    Shen, H.2
  • 22
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300:339.
    • (2003) Science , vol.300 , pp. 339
    • Sun, J.C.1    Bevan, M.J.2
  • 23
    • 0034749543 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site
    • Buck, C. B., X. Shen, M. A. Egan, T. C. Pierson, C. M. Walker, and R. F. Siliciano. 2001. The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site. J. Virol. 75:181.
    • (2001) J. Virol. , vol.75 , pp. 181
    • Buck, C.B.1    Shen, X.2    Egan, M.A.3    Pierson, T.C.4    Walker, C.M.5    Siliciano, R.F.6
  • 24
    • 0024562943 scopus 로고
    • The degradation signal in a short-lived protein
    • Bachmair, A., and A. Varshavsky. 1989. The degradation signal in a short-lived protein. Cell 56:1019.
    • (1989) Cell , vol.56 , pp. 1019
    • Bachmair, A.1    Varshavsky, A.2
  • 26
    • 0026715925 scopus 로고
    • The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions
    • Yu, X., X. Yuan, Z. Matsuda, T.-H. Lee, and M. Essex. 1992. The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions. J. Virol. 66:4966.
    • (1992) J. Virol. , vol.66 , pp. 4966
    • Yu, X.1    Yuan, X.2    Matsuda, Z.3    Lee, T.-H.4    Essex, M.5
  • 27
    • 0002777678 scopus 로고
    • Expression of proteins in mammalian cells using vaccinia viral vectors
    • F. M. Ausubel, R. Brent, R. E. Kingston, D. M. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, eds. Wiley Interscience, New York
    • Moss, B., and P. L. Earl. 1991. Expression of proteins in mammalian cells using vaccinia viral vectors. In Current Protocols in Molecular Biology. F. M. Ausubel, R. Brent, R. E. Kingston, D. M. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, eds. Wiley Interscience, New York, pp. 16.15.1-16.16.7.
    • (1991) Current Protocols in Molecular Biology , vol.15
    • Moss, B.1    Earl, P.L.2
  • 28
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
    • Porgador, A., J. W. Yewdell, Y. Deng, J. R. Bennink, and R. N. Germain. 1997. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 6:715.
    • (1997) Immunity , vol.6 , pp. 715
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.3    Bennink, J.R.4    Germain, R.N.5
  • 29
    • 0032530748 scopus 로고    scopus 로고
    • The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D
    • Mata, M., P. J. Travers, Q. Liu, F. R. Frankel, and Y. Paterson. 1998. The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D. J. Immunol. 161:2985.
    • (1998) J. Immunol. , vol.161 , pp. 2985
    • Mata, M.1    Travers, P.J.2    Liu, Q.3    Frankel, F.R.4    Paterson, Y.5
  • 30
  • 31
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129.
    • (1990) Cell , vol.63 , pp. 1129
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 32
    • 0032472322 scopus 로고    scopus 로고
    • The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor
    • Byrd, C., G. C. Turner, and A. Varshavsky. 1998. The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. EMBO J. 17:269.
    • (1998) EMBO J. , vol.17 , pp. 269
    • Byrd, C.1    Turner, G.C.2    Varshavsky, A.3
  • 33
    • 0030068265 scopus 로고    scopus 로고
    • Class I-restricted presentation of an HIV-1 gp41 epitope containing an N-linked glycosylation site: Implications for the mechanism of processing of viral envelope proteins
    • Ferris, R. L., C. Buck, S. A. Hammond, A. S. Woods, R. J. Cotter, M. Takiguchi, Y. Igarashi, Y. Ichikawa, and R. F. Siliciano. 1996. Class I-restricted presentation of an HIV-1 gp41 epitope containing an N-linked glycosylation site: implications for the mechanism of processing of viral envelope proteins. J. Immunol. 156:834.
    • (1996) J. Immunol. , vol.156 , pp. 834
    • Ferris, R.L.1    Buck, C.2    Hammond, S.A.3    Woods, A.S.4    Cotter, R.J.5    Takiguchi, M.6    Igarashi, Y.7    Ichikawa, Y.8    Siliciano, R.F.9
  • 34
    • 0028234481 scopus 로고
    • Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production
    • Freed, E. O., J. M. Orenstein, A. J. Buckler-White, and M. A. Martin. 1994. Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production. J. Virol. 68:5311.
    • (1994) J. Virol. , vol.68 , pp. 5311
    • Freed, E.O.1    Orenstein, J.M.2    Buckler-White, A.J.3    Martin, M.A.4
  • 35
    • 0023003380 scopus 로고
    • In vivo half-life of a protein is a function of its amino-terminal residue
    • Bachmair, A., D. Finley, and A. Varshavsky. 1986. In vivo half-life of a protein is a function of its amino-terminal residue. Science 234:179.
    • (1986) Science , vol.234 , pp. 179
    • Bachmair, A.1    Finley, D.2    Varshavsky, A.3
  • 36
    • 0026766091 scopus 로고
    • The N-end rule
    • Varshavsky, A. 1992. The N-end rule. Cell 69:725.
    • (1992) Cell , vol.69 , pp. 725
    • Varshavsky, A.1
  • 37
    • 0021798139 scopus 로고
    • Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate
    • Dahlmann, B., M. Rutschmann, L. Kuehn, and H. Reinauer. 1985. Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate. Biochem. J. 228:171.
    • (1985) Biochem. J. , vol.228 , pp. 171
    • Dahlmann, B.1    Rutschmann, M.2    Kuehn, L.3    Reinauer, H.4
  • 38
    • 0020479850 scopus 로고
    • Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells: Relationship to the breakdown of abnormal proteins
    • Hershko, A., E. Eytan, A. Ciechanover, and A. L. Haas. 1982. Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells: relationship to the breakdown of abnormal proteins. J. Biol. Chem. 257:13964.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13964
    • Hershko, A.1    Eytan, E.2    Ciechanover, A.3    Haas, A.L.4
  • 39
    • 0029095673 scopus 로고
    • Roles of ubiquitinylation in proteolysis and cellular regulation
    • Wilkinson, K. D. 1995. Roles of ubiquitinylation in proteolysis and cellular regulation. Annu. Rev. Nutr. 15:161.
    • (1995) Annu. Rev. Nutr. , vol.15 , pp. 161
    • Wilkinson, K.D.1
  • 41
    • 0036547263 scopus 로고    scopus 로고
    • New hope for an AIDS vaccine
    • Robinson, H. L. 2002. New hope for an AIDS vaccine. Nat. Rev. Immunol. 2:239.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 239
    • Robinson, H.L.1
  • 43
    • 0030239693 scopus 로고    scopus 로고
    • Defective ribosomal products (DRiPs): A major source of antigenic peptides for MHC class I molecules?
    • Yewdell, J. W., L. C. Anton, and J. R. Bennink. 1996. Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules? J. Immunol. 157:1823.
    • (1996) J. Immunol. , vol.157 , pp. 1823
    • Yewdell, J.W.1    Anton, L.C.2    Bennink, J.R.3
  • 44
    • 0025805695 scopus 로고
    • Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes
    • Alexander, M. A., C. A. Damico, K. M. Wieties, T. H. Hansen, and J. M. Connolly. 1991. Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes. J. Exp. Med. 173:849.
    • (1991) J. Exp. Med. , vol.173 , pp. 849
    • Alexander, M.A.1    Damico, C.A.2    Wieties, K.M.3    Hansen, T.H.4    Connolly, J.M.5
  • 45
  • 46
    • 0020077493 scopus 로고
    • Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
    • Keene, J. A., and J. Forman. 1982. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med. 155:768.
    • (1982) J. Exp. Med. , vol.155 , pp. 768
    • Keene, J.A.1    Forman, J.2
  • 49
  • 52
    • 17944376032 scopus 로고    scopus 로고
    • Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: Differential modulation by T helper type 1 and type 2 cells
    • Medema, J. P., D. H. Schuurhuis, D. Rea, J. van Tongeren, J. de Jong, S. A. Bres, S. Laban, R. E. Toes, M. Toebes, T. N. Schumacher, et al. 2001. Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells. J. Exp. Med. 194:657.
    • (2001) J. Exp. Med. , vol.194 , pp. 657
    • Medema, J.P.1    Schuurhuis, D.H.2    Rea, D.3    Van Tongeren, J.4    De Jong, J.5    Bres, S.A.6    Laban, S.7    Toes, R.E.8    Toebes, M.9    Schumacher, T.N.10
  • 54
    • 0037398404 scopus 로고    scopus 로고
    • Feedback regulation of pathogen-specific T cell priming
    • Wong, P., and E. G. Pamer. 2003. Feedback regulation of pathogen-specific T cell priming. Immunity 18:499.
    • (2003) Immunity , vol.18 , pp. 499
    • Wong, P.1    Pamer, E.G.2
  • 55
    • 0029737350 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells
    • Doe, B., M. Selby, S. Barnett, J. Baenziger, and C. M. Walker. 1996. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl. Acad. Sci. USA 93:8578.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8578
    • Doe, B.1    Selby, M.2    Barnett, S.3    Baenziger, J.4    Walker, C.M.5
  • 56
    • 0029080474 scopus 로고
    • Exposing the immunology of naked DNA vaccines
    • Pardoll, D. M., and A. M. Beckerleg. 1995. Exposing the immunology of naked DNA vaccines. Immunity 3:165.
    • (1995) Immunity , vol.3 , pp. 165
    • Pardoll, D.M.1    Beckerleg, A.M.2
  • 57
    • 0033522179 scopus 로고    scopus 로고
    • Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen
    • Sigal, L. J., S. Crotty, R. Andino, and K. L. Rock. 1999. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature 398:77.
    • (1999) Nature , vol.398 , pp. 77
    • Sigal, L.J.1    Crotty, S.2    Andino, R.3    Rock, K.L.4
  • 58
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTL
    • Albert, M. L., B. Sauter, and N. Bhardwaj. 1998. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTL. Nature 392:86.
    • (1998) Nature , vol.392 , pp. 86
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.