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Volumn 14, Issue 5, 2004, Pages 257-270

Comparison of basal gene expression in cultured primary rat hepatocytes and freshly isolated rat hepatocytes

Author keywords

Collagen I; Filter array; Gene expression; Matrigel; Primary hepatocytes

Indexed keywords

COLLAGEN TYPE 1; MATRIGEL;

EID: 4344651175     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376520490434629     Document Type: Article
Times cited : (6)

References (39)
  • 1
    • 0018570460 scopus 로고
    • Comparison of cytochrome P-450 levels in adult rat liver, postnatal rat liver, and primary cultures of postnatal rat hepatocytes
    • Acosta, D., Anuforo, D. C., McMillin, R., Soine, W. H., and Smith, R. V. 1979. Comparison of cytochrome P-450 levels in adult rat liver, postnatal rat liver, and primary cultures of postnatal rat hepatocytes. Life Sciences 25:1413-1418.
    • (1979) Life Sciences , vol.25 , pp. 1413-1418
    • Acosta, D.1    Anuforo, D.C.2    McMillin, R.3    Soine, W.H.4    Smith, R.V.5
  • 3
    • 0021126053 scopus 로고
    • Prolonged maintenance of active cytochrome P-450 in adult rat hepatocytes co-cultured with another liver cell type
    • Begue, J. M., Guguen-Guillouzo, C., Pasdeloup, N., and Guillouzo, A. 1984. Prolonged maintenance of active cytochrome P-450 in adult rat hepatocytes co-cultured with another liver cell type. Hepatology 4:839-842.
    • (1984) Hepatology , vol.4 , pp. 839-842
    • Begue, J.M.1    Guguen-Guillouzo, C.2    Pasdeloup, N.3    Guillouzo, A.4
  • 4
    • 0024121578 scopus 로고
    • Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes
    • Ben-Ze'ev, A., Robinson, G. S., Bucher, N. L., and Farmer, S. R. 1988. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc. Natl. Acad. Sci. USA 85:2161-2165.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2161-2165
    • Ben-Ze'ev, A.1    Robinson, G.S.2    Bucher, N.L.3    Farmer, S.R.4
  • 6
    • 0038172423 scopus 로고    scopus 로고
    • Gene expression in two hepatic cell lines, cultured primary hepatocytes and liver slices compared to the in vivo liver gene expression in rats: Possible implications for toxicogenomics use of in vitro systems
    • Boess, F., Kamber, M., Romer, S., Gasser, R., Muller, D., Albertini, S., and Suter, L. 2003. Gene expression in two hepatic cell lines, cultured primary hepatocytes and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems. Toxicol. Sci. 73:386-402.
    • (2003) Toxicol. Sci. , vol.73 , pp. 386-402
    • Boess, F.1    Kamber, M.2    Romer, S.3    Gasser, R.4    Muller, D.5    Albertini, S.6    Suter, L.7
  • 7
    • 0025306273 scopus 로고
    • Effects of extracellular matrix on hepatocyte growth and gene expression: Implication for hepatic regeneration and the repair of liver injury
    • Bucher, N. L., Robinson, G. S., and Farmer, S. R. 1990. Effects of extracellular matrix on hepatocyte growth and gene expression: implication for hepatic regeneration and the repair of liver injury. Semin. Liv. Dis. 10:11-19.
    • (1990) Semin. Liv. Dis. , vol.10 , pp. 11-19
    • Bucher, N.L.1    Robinson, G.S.2    Farmer, S.R.3
  • 9
    • 0020822437 scopus 로고
    • Changes in liver specific compared to common gene transcription during primary culture of mouse hepatocytes
    • Clayton, D., and Darnell, J. 1983. Changes in liver specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol. Cell Biol. 3:1552-1561.
    • (1983) Mol. Cell Biol. , vol.3 , pp. 1552-1561
    • Clayton, D.1    Darnell, J.2
  • 10
    • 0023907035 scopus 로고
    • Long-term culture of hepatocytes: Effects of hormones on enzyme activities and metabolic capacity
    • Dich, J., Vind, C., and Grunnet, N. 1988. Long-term culture of hepatocytes: effects of hormones on enzyme activities and metabolic capacity. Hepatology 8:39-45.
    • (1988) Hepatology , vol.8 , pp. 39-45
    • Dich, J.1    Vind, C.2    Grunnet, N.3
  • 11
    • 0027427302 scopus 로고
    • Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes
    • Ezzell, R. M., Toner, M., Hendrick, K., Dunn, J. C., Tompkins, R. G., and Yarmush, M. L. 1993. Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes. Exp. Cell Res. 208:442-452.
    • (1993) Exp. Cell Res. , vol.208 , pp. 442-452
    • Ezzell, R.M.1    Toner, M.2    Hendrick, K.3    Dunn, J.C.4    Tompkins, R.G.5    Yarmush, M.L.6
  • 13
    • 0001225912 scopus 로고
    • Role of cell shape in growth control
    • Folkman, J., and Mosconoa, A. 1978. Role of cell shape in growth control. Nature 346:760-763.
    • (1978) Nature , vol.346 , pp. 760-763
    • Folkman, J.1    Mosconoa, A.2
  • 14
    • 0346942394 scopus 로고    scopus 로고
    • Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays
    • Gerhold, D., Lu, M., Xu, J., Austin, C., Caskey, C. T., and Rushmore, T. 2001. Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays. Physiol. Genomics 5:161-170.
    • (2001) Physiol. Genomics , vol.5 , pp. 161-170
    • Gerhold, D.1    Lu, M.2    Xu, J.3    Austin, C.4    Caskey, C.T.5    Rushmore, T.6
  • 17
    • 0020688509 scopus 로고
    • Modulation of functional activities in cultured rat hepatocytes
    • Guguen-Guillouzo, C., and Guillouzo, A. 1983. Modulation of functional activities in cultured rat hepatocytes. Molec. Cell Biol. 53/54:35-36.
    • (1983) Molec. Cell Biol. , vol.53-54 , pp. 35-36
    • Guguen-Guillouzo, C.1    Guillouzo, A.2
  • 18
    • 0032845724 scopus 로고    scopus 로고
    • Regulation of the hepatocyte cell cycle by type I collagen matrix: Role of cyclin D1
    • Hansen, L. K., and Albrecht, J. H. 1999. Regulation of the hepatocyte cell cycle by type I collagen matrix: role of cyclin D1. J. Cell Sci. 112:2971-2981.
    • (1999) J. Cell Sci. , vol.112 , pp. 2971-2981
    • Hansen, L.K.1    Albrecht, J.H.2
  • 19
    • 0023514563 scopus 로고
    • Adhesive interactions and the metabolic activity of hepatocytes
    • Hughes, R. C., and Stamatoglou, S. C. 1987. Adhesive interactions and the metabolic activity of hepatocytes. J. Cell Sci. Suppl. 8:273-292.
    • (1987) J. Cell Sci. Suppl. , vol.8 , pp. 273-292
    • Hughes, R.C.1    Stamatoglou, S.C.2
  • 20
    • 0035328520 scopus 로고    scopus 로고
    • Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia
    • Kitahara, O., Furukawa, Y., Tanaka, T., Kihara, C., Ono, K., Yanagawa, R., Nita, M. E., Takagi, T., Nakamura Y., and Tsunoda, T. 2001. Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res. 61:3544-3549.
    • (2001) Cancer Res. , vol.61 , pp. 3544-3549
    • Kitahara, O.1    Furukawa, Y.2    Tanaka, T.3    Kihara, C.4    Ono, K.5    Yanagawa, R.6    Nita, M.E.7    Takagi, T.8    Nakamura, Y.9    Tsunoda, T.10
  • 21
    • 0020360978 scopus 로고
    • Isolation and characterization of type IV procollagen, laminin and heparin sulfate proteoglycan from the EHS sarcoma
    • Kleinman, H. K., McGarvey, M. L., Liotta, L. A., Robey, P. G., Tryggvason, K., and Martin, G. R. 1982. Isolation and characterization of type IV procollagen, laminin and heparin sulfate proteoglycan from the EHS sarcoma. Biochemistry 21:6188-6193.
    • (1982) Biochemistry , vol.21 , pp. 6188-6193
    • Kleinman, H.K.1    McGarvey, M.L.2    Liotta, L.A.3    Robey, P.G.4    Tryggvason, K.5    Martin, G.R.6
  • 22
    • 0016137515 scopus 로고
    • Alpha-fetoprotein biosynthesis during the growth cycle of differentiated fetal rat hepatocytes in primary monolayer culture
    • Leffert, H. L., and Sell, S. 1974. Alpha-fetoprotein biosynthesis during the growth cycle of differentiated fetal rat hepatocytes in primary monolayer culture. J. Biol. Chem. 61:823-829.
    • (1974) J. Biol. Chem. , vol.61 , pp. 823-829
    • Leffert, H.L.1    Sell, S.2
  • 23
    • 0030005755 scopus 로고    scopus 로고
    • The I.M.A.G.E. consortium: An integrated molecular analysis of genomes and their expression
    • Lennon, G.G., Auffray, C., Polymeropoulos, M., and Soares, M.B. 1996. The I.M.A.G.E. consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152.
    • (1996) Genomics , vol.33 , pp. 151-152
    • Lennon, G.G.1    Auffray, C.2    Polymeropoulos, M.3    Soares, M.B.4
  • 24
    • 0027227345 scopus 로고
    • The hepatic extracellular matrix. 1. Components and distribution in normal liver
    • Martinez-Hernandez, A., and Amenta, P. S. 1984. The hepatic extracellular matrix. 1. Components and distribution in normal liver. Virchows Arch. [A] 423:1-11.
    • (1984) Virchows Arch. [A] , vol.423 , pp. 1-11
    • Martinez-Hernandez, A.1    Amenta, P.S.2
  • 25
    • 0025737166 scopus 로고
    • Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone
    • McMillan, J. M., Shaddock, J. G., Casciano, D. A., Arlotto, M. P., and Leakey, J. E. 1991. Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone. Mutat. Res. 249:81-92.
    • (1991) Mutat. Res. , vol.249 , pp. 81-92
    • McMillan, J.M.1    Shaddock, J.G.2    Casciano, D.A.3    Arlotto, M.P.4    Leakey, J.E.5
  • 26
    • 0029064234 scopus 로고
    • Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix
    • Mooney, D. J., Langer, R., and Ingber, D. E. 1995. Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix. J. Cell Sci. 108:2311-2320.
    • (1995) J. Cell Sci. , vol.108 , pp. 2311-2320
    • Mooney, D.J.1    Langer, R.2    Ingber, D.E.3
  • 27
    • 0034010320 scopus 로고    scopus 로고
    • Control of cyclins, cyclin-dependent kinase inhibitors, p21 and p27, and cell cycle progression in rat hepatocytes by extracellular matrix
    • Nagaki, M., Sugiyama, S., Naiki, T., Ohsawa, Y., and Moriwaki, H. 2000. Control of cyclins, cyclin-dependent kinase inhibitors, p21 and p27, and cell cycle progression in rat hepatocytes by extracellular matrix. J. Hepatol. 32:488-496.
    • (2000) J. Hepatol. , vol.32 , pp. 488-496
    • Nagaki, M.1    Sugiyama, S.2    Naiki, T.3    Ohsawa, Y.4    Moriwaki, H.5
  • 28
    • 0000145245 scopus 로고
    • The isolation and primary culture of viable, nonproliferating rat hepatocytes
    • Oldham, J. W., Casciano, D. A., and Farr, J. A. 1979. The isolation and primary culture of viable, nonproliferating rat hepatocytes. TCA Manual 5:1047-1050.
    • (1979) TCA Manual , vol.5 , pp. 1047-1050
    • Oldham, J.W.1    Casciano, D.A.2    Farr, J.A.3
  • 30
    • 0035087788 scopus 로고    scopus 로고
    • Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix
    • Otsu, K., Ito, K., Kuzumaki, T., and Iuchi, Y. 2000. Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix. Cell Physiol. Biochem. 11:33-40.
    • (2000) Cell Physiol. Biochem. , vol.11 , pp. 33-40
    • Otsu, K.1    Ito, K.2    Kuzumaki, T.3    Iuchi, Y.4
  • 31
    • 0027389277 scopus 로고
    • Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes
    • Padgham, C. R., and Paine, A. J. 1993. Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes. Biochem. J. 289:621-624.
    • (1993) Biochem. J. , vol.289 , pp. 621-624
    • Padgham, C.R.1    Paine, A.J.2
  • 32
    • 0035818559 scopus 로고    scopus 로고
    • Project normal: Defining normal variance in mouse gene expression
    • Pritchard, C. C., Hsu, L., Delrow, J., and Nelson, P. S. 2001. Project normal: defining normal variance in mouse gene expression. PNAS 98:13266-13271.
    • (2001) PNAS , vol.98 , pp. 13266-13271
    • Pritchard, C.C.1    Hsu, L.2    Delrow, J.3    Nelson, P.S.4
  • 33
    • 0004222754 scopus 로고    scopus 로고
    • Code available at
    • Rozen, S., and Skaletsky, H. J. 1996. Primer3. Code available at http://www-genome.wi.mit.edu/genome_software/other/primer3.html
    • (1996) Primer3
    • Rozen, S.1    Skaletsky, H.J.2
  • 35
    • 0029117356 scopus 로고
    • Genotoxicity of tacrine in primary isolated hepatocytes from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats
    • Shaddock, J. G., Feuers, R. J., Chou, M. W., Swenson, D. H., and Casciano D. A. 1995. Genotoxicity of tacrine in primary isolated hepatocytes from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats. Mutat. Res. 344:79-88.
    • (1995) Mutat. Res. , vol.344 , pp. 79-88
    • Shaddock, J.G.1    Feuers, R.J.2    Chou, M.W.3    Swenson, D.H.4    Casciano, D.A.5
  • 36
    • 0026692903 scopus 로고
    • c-Myc expression is down-regulated by cell-cell and cell-extracellular matrix contacts in normal hepatocytes, but not in hepatoma cells
    • Shimbara, N., Takashina M., Sato, C., Iizuka, M., Kobayashi, S., Tanaka, K., and Ichihara, A. 1992. c-Myc expression is down-regulated by cell-cell and cell-extracellular matrix contacts in normal hepatocytes, but not in hepatoma cells. Biochem. Biophys. Res. Commun. 184:825-831.
    • (1992) Biochem. Biophys. Res. Commun. , vol.184 , pp. 825-831
    • Shimbara, N.1    Takashina, M.2    Sato, C.3    Iizuka, M.4    Kobayashi, S.5    Tanaka, K.6    Ichihara, A.7
  • 37
    • 0026701412 scopus 로고
    • Identification of multiple active growth factors in basement membrane matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components
    • Vukicevic, S., Kleinman, H. K., Luyten, F. P., Roberts, A. B., Roche, N. S., and Reddi, A. H. 1992. Identification of multiple active growth factors in basement membrane matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components. Exp. Cell Res. 202:1-8.
    • (1992) Exp. Cell Res. , vol.202 , pp. 1-8
    • Vukicevic, S.1    Kleinman, H.K.2    Luyten, F.P.3    Roberts, A.B.4    Roche, N.S.5    Reddi, A.H.6
  • 38
    • 0035977845 scopus 로고    scopus 로고
    • Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity
    • Waring, J. F., Ciurlionis, R., Jolly, R. A., Heindel, M., and Ulrich, R. G. 2001. Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicol. Lett. 120:359-368.
    • (2001) Toxicol. Lett. , vol.120 , pp. 359-368
    • Waring, J.F.1    Ciurlionis, R.2    Jolly, R.A.3    Heindel, M.4    Ulrich, R.G.5


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