Silymarin protects against liver damage in BALB/c mice exposed to Fumonisin B1 despite increasing accumulation of free sphingoid bases

Toxicological Sciences

Volumn 80, Issue 2, 2004, Pages 335-342

  He, Quanren ^a   Kim, Jiyoung ^a   Sharma, Raghubir P ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Fumonisin B1; Hepatotoxicity; Silymarin; Sphingolipid; Tumor necrosis factor

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FUMONISIN B1; GAMMA INTERFERON; LYMPHOTOXIN BETA; SILYMARIN; SPHINGANINE; SPHINGOSINE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FEEDING; FEMALE; LIVER CELL; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TISSUE DISTRIBUTION;

ACYLTRANSFERASES; ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CARCINOGENS, ENVIRONMENTAL; CELL PROLIFERATION; CYTOKINES; FEMALE; FUMONISINS; HEPATITIS, TOXIC; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; KIDNEY; LIVER; MICE; MICE, INBRED BALB C; NUCLEASE PROTECTION ASSAYS; PROLIFERATING CELL NUCLEAR ANTIGEN; SERINE C-PALMITOYLTRANSFERASE; SILYMARIN; SPHINGOSINE;

ANIMALIA; EQUIDAE; FUSARIUM; GIBBERELLA MONILIFORMIS; SPHINGIODEA; SUIDAE; ZEA MAYS;

EID: 4344629494     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh148     Document Type: Article

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