Analysis of fumonisin B1-induced apoptosis

Environmental Health Perspectives

Volumn 109, Issue SUPPL. 2, 2001, Pages 315-320

  Jones, Clinton ^a   Ciacci Zanella, Janice R ^a   Zhang, Yange ^a   Henderson, Gail ^a   Dickman, Martin ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Apoptosis; Fumonisin B1; Mycotoxins; Signal transduction; Tumor necrosis factor

Indexed keywords

CASPASE 8; CERAMIDE SYNTHASE; FUMONISIN B1; MYCOTOXIN; PROTEIN BCL 2; PROTEIN P53; SYNTHETASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CARBOXYLIC ACID; CARCINOGEN; CASPASE; CYCLIN DEPENDENT KINASE; DNA FRAGMENT; DRUG DERIVATIVE; FUMONISIN; SPHINGOSINE; TUMOR NECROSIS FACTOR ALPHA;

AFRICA; ANIMAL CELL; APOPTOSIS; ARTICLE; BACULOVIRUS; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROTECTION; CELL TRANSFORMATION; CEREAL; CHEMICAL STRUCTURE; CONTROLLED STUDY; CORN; EMBRYO; ENZYME DEGRADATION; ENZYME INHIBITION; FIBROBLAST; FUSARIUM MONILIFORME; GENE; GROWTH REGULATION; INFORMATION; KIDNEY; MAMMAL CELL; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOXICITY; TUMOR SUPPRESSOR GENE; VIRUS GENE; ANIMAL; BACTERIUM TRANSFORMATION; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; PLASMID; SEQUENCE ALIGNMENT;

ANIMALS; APOPTOSIS; BACULOVIRIDAE; CARBOXYLIC ACIDS; CARCINOGENS, ENVIRONMENTAL; CASPASES; CELLS, CULTURED; CYCLIN-DEPENDENT KINASES; DNA FRAGMENTATION; FIBROBLASTS; FUMONISINS; GENES, P53; GENES, VIRAL; MICE; MYCOTOXINS; PLASMIDS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SPHINGOSINE; TRANSFORMATION, BACTERIAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035021638     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109s2315     Document Type: Article

References (54)

1. Fusarium diseases of wheat, maize, and grain sorghum in Eastern Australia
2. Fusarium diseases of wheat and corn in Western Europe
3. Fusarium diseases of wheat and other small grains in North America
4. Fusarium diseases in the People's Republic of China
5. Root-, stalk-, and ear-infecting Fusarium species on corn in the USA
6. Fusarium diseases of wheat and corn in Eastern Europe and the Soviet Union
7. The Bakanae disease of the rice plant
8. Fumonisins and other inhibitors of de novo sphingolipid biosynthesis
9. Fumonisins: Fungal toxins that shed light on sphingolipid function
10. Sphingolipid metabolism and growth regulation: A state of the art review
11. 1, a mycotoxin produced by Fusarium moniliforme in corn
12. Fumonisin as a possible contributory risk factor for primary liver cancer: A 3-year study of corn harvested in Haimen, China by HPLC and ELISA
13. Mycotoxicological investigations on corn produced in esophageal cancer areas in Transkei
14. 1 in rats
15. The cancer initiating potential of the fumonisin-B mycotoxins
16. Carcinogenicity of Fusarium moniliforme culture media in rats
17. Fumonisins-novel mycotoxins with cancer promoting activity produced by Fusarium moniliforme
18. Leukoencephalomalacia: A mycotoxicosis of Equidae caused by Fusarium moniliforme Sheldon
19. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity
20. 1, a toxic metabolite of Fusarium moniliforme
21. 1
22. 1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: A new mechanism of nephrotoxicity
23. 1 in rabbits: Nephrotoxocity and sphingolipid alterations
24. 1 induces cell proliferation and apoptosis in the rat
25. 1
26. The mycotoxin fumonisin induces apoptosis in cultured human cells and in livers and kidneys of rats
27. 1, a mycotoxin contaminant of cereal grains, induces apoptosis via the tumor necrosis factor pathway and caspase activation but does not require p53
28. 1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases
29. Fumonisins and AAL toxins: Sphinganine analog mycotoxins induce apoptosis in monkey kidney cells
30. 1 in CV-1 cells
31. Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
32. Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells
33. Life, death, and the pursuit of apoptosis
34. A new technique for the assay of infectivity of human adenovirus 5 DNA
35. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme
36. Control of programmed cell death by the baculovirus genes p35 and iap
37. Yama/CPP32b, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
38. 1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites
39. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
40. Dissection of TNF receptor 1-effectors functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
41. IAP family proteins-suppressors of apoptosis
42. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHα1) death signal
43. Activation of human immunodeficiency virus by herpesvirus infection: Identification of a region within the long terminal repeat that responds to a transacting factor encoded by herpes simplex virus type 1
44. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of cdk2: Role of a caspase cascade
45. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
46. Human IAP-like protein regulates programmed cell death downstream of Bcl-XL and cytochrome c
47. 1
48. Bik and Bak induce apoptosis downstream of crmA but upstream of inhibitor of apoptosis
49. Caspase-9 can be activated without proteolytic processing
50. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
51. Repression of protein kinase C and stimulation of cyclic AMP response element by fumonisin, a fungal encoded toxin which is a carcinogen
52. 1 toxicity
53. Dietary Fusarium moniloforme culture material induces in vitro tumor necrosis factor-alpha like activity in the sera of swine