Fumonisin toxicosis in swine: An overview of porcine pulmonary edema and current perspectives

Environmental Health Perspectives

Volumn 109, Issue SUPPL. 2, 2001, Pages 251-257

  Haschek, Wanda M ^a   Gumprecht, Laura A ^b   Smith, Geoffrey ^a   Tumbleson, Mike E ^a   Constable, Peter D ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cardiovascular; Fumonisin; Immune system; Liver; Pulmonary edema; Sphinganine; Sphingosine; Swine

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; CHOLESTEROL; FUMONISIN B1; SPHINGANINE; SPHINGOLIPID; SPHINGOSINE;

ACUTE HEART FAILURE; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR EFFECT; CAUSE OF DEATH; CELL PROLIFERATION; CELL TYPE; CHOLESTEROL BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORN; DISEASE SEVERITY; ENDOTHELIUM CELL; EPIDEMIC; ESOPHAGUS DISEASE; FOOD CONTAMINATION; FUNGUS CULTURE; FUSARIUM MONILIFORME; HEART; HEART LEFT VENTRICLE CONTRACTILITY; HEART OUTPUT; HEART RATE; HEART RIGHT VENTRICLE HYPERTROPHY; IMMUNE RESPONSE; KIDNEY; LIPOGENESIS; LIVER; LIVER CELL; LIVER HYPERPLASIA; LIVER INJURY; LIVER NECROSIS; LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG ARTERY PRESSURE; LUNG CAPILLARY; LUNG EDEMA; LUNG WEDGE PRESSURE; MEAN ARTERIAL PRESSURE; MYCOTOXICOSIS; NONHUMAN; PATHOGENESIS; PATHOLOGY; PHAGOCYTOSIS; PRIORITY JOURNAL; SCREENING; SPECIES DIFFERENCE; SWINE DISEASE; UNITED STATES;

FUSARIUM MONILIFORME; FUSARIUM VERTICILLIOIDES;

EID: 0035000827     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109s2251     Document Type: Article

References (69)

1. Fumonisin contamination of commercial corn-based human foodstuffs
2. 2 in corn-based products
3. 1 isolated from Fusarium moniliforme
4. 1, a toxic metabolite of Fusarium moniliforme
5. 1
6. Chronic effects of dietary fumonisin on the heart and pulmonary vasculature of swine
7. Acute hepatic and renal toxicity in lambs dosed with fumonisin-containing culture material
8. 1 in rabbits: Nephrotoxicity and sphingolipid alterations
9. Cardiovascular responses to short-term fumonisin exposure in swine
10. Cardiovascular effects of fumonisins in swine
11. A comparative study of the toxicity of Fusarium verticillioides (= F. moniliforme) to horses, primates, pigs, sheep and rats
12. Characterization of an epizootic of pulmonary edema in swine associated with fumonisin in corn screenings
13. Fumonisin-induced pulmonary edema and hydrothorax in swine
14. 1 contamination of maize and experimental acute fumonisin toxicosis in pigs
15. Fumonisin toxicosis in swine: Clinical and pathologic findings
16. Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: Morphological and biochemical alterations
17. Occurrence of fumonisins and aflatoxins in the south Georgia corn survey from 1996 to 1999
18. Fumonisins levels in corn and corn products-global perspectives
19. Relationship between fumonisin contamination of feed and mystery swine disease. A case-control study
20. Fumonisin occurrence in corn from high- and low-risk areas for human esophageal cancer in China
21. Fumonisins and neural tube defects in south Texas
22. 1 in rats
23. 1 in rats
24. 1 in rats
25. 1 in male Sprague-Dawley rats
26. 1 in swine
27. 1
28. Characterization of fumonisin toxicity in orally and intravenously dosed swine
29. Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins
30. 2 and fusarin C
31. 3 cause hepato- and nephrotoxicity in rats
32. Investigation into the effect of toxins produced by Fusarium moniliforme in pigs. I: Definition of tolerance limit values in weaned piglets
33. Investigation into the effect of toxins produced by Fusarium moniliforme in pigs. II. Examination of perinatal toxicosis in pregnant sows and newborn piglets
34. Sequence of cardiovascular changes leading to pulmonary edema in swine fed fumonisin-containing culture material
35. 1-containing culture material decreases cardiac contractility and mechanical efficiency in swine
36. 1 decreases cardiovascular function but does not alter pulmonary capillary permeability
37. Alteration of tissue and serum sphinganine to sphingosine ratio: An early biomaker of exposure to fumonisin-containing feeds in pigs
38. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme
39. Chronic toxicity of fumonisin in weanling pigs
40. Chronic consumption of fumonisins derived from Fusarium moniliforme culture material: Clinical and pathologic effects in swine
41. Effects of fumonisins in swine: Implications for biomedical research
42. 1 during an eight-week period: Growth and clinical parameters
43. 1 on various metabolic parameters and carcass quality of growing-finishing swine-preliminary findings
44. Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: Specificity of the response and structure-activity relationships
45. Fumonisin toxicity and sphingolipid biosynthesis
46. Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins
47. 1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: A new mechanism of nephrotoxicity
48. Increases in serum sphingosine and sphinganine and decreases in complex sphingolipids in ponies given feed containing fumonisins, mycotoxins produced by Fusarium moniliforme
49. Species and organ specificity of fumonisin-induced endothelial alterations: Potential role in porcine pulmonary edema
50. 1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture
51. Fumonisin induced morphologic alterations in porcine pulmonary endothelial (PE) cells in vivo did not occur in vitro
52. Effects of fumonisin on left ventricular afterload in swine
53. Immunomodulation in aflatoxicosis
54. The immunotoxicity of trichothecene mycotoxins
55. 1
56. 1 in lactating sows and their suckling pigs
57. 1-containing culture material on growing barrows
58. 1-containing culture material, deoxynivalenol-contaminated wheat, or their combination on growing barrows
59. Effects of fumonisin on specific and nonspecific immunity in pigs after pseudorabies vaccination
60. Pulmonary clearance of blood-borne bacteria
61. Effects of fumonisin-containing culture material on pulmonary clearance in swine
62. 1 alters sphingolipid biosynthesis and inhibits bacterial phagocytosis
63. Fumonisin alters macrophage activation as measured by luminol-dependent chemiluminescence
64. Regulatory aspects of fumonisins with respect to animal feed
65. 1 exposure increases pig susceptibility to E. coli infection
66. Atherogenic effects in a non-human primate of Fusarium moniliforme cultures added to a carbohydrate diet [published erratum appears in Atherosclerosis 96(1):87 (1992)]