Reduction of anti-Galα1,3Gal antibodies by infusion of types 2 and 6 gal trisaccharides conjugated to poly-L-lysine

Xenotransplantation

Volumn 11, Issue 2, 2004, Pages 210-215

  Kuwaki, K ^a   Knosalla, C ^a   Moran, K ^b   Alt, A ^b   Katopodis, A G ^c   Duthaler, R O ^c   Schuurman, H J ^b   Awwad, M ^b   Cooper, D K C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Immerge Biotherapeutics Inc   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Anti Gal antibodies; Baboons; Gal 1,3Gal; Poly l lysine; Soluble Gal conjugates

Indexed keywords

ANTIBODY; GALACTOSE TRISACCHARIDE TYPE 2; GALACTOSE TRISACCHARIDE TYPE 6; GALACTOSYL ALPHA 1,3 GALACTOSYL BETA 1,4 GLUCOSE; GALACTOSYL ALPHA 1,3 GALACTOSYL BETA 1,4 N ACETYLGLUCOSAMINE; GALACTOSYLGALACTOSE; GALACTOSYLGALACTOSE ANTIBODY; GLYCOCONJUGATE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; POLYLYSINE; POLYLYSINE GALACTOSYL ALPHA 1,3 GALACTOSYL BETA 1,4 GLUCOSE CONJUGATE; POLYLYSINE GALACTOSYL ALPHA 1,3 GALACTOSYL BETA 1,4 N ACETYLGLUCOSAMINE CONJUGATE; TRISACCHARIDE; UNCLASSIFIED DRUG; DISACCHARIDE; EPITOPE; GALACTOSE; GALACTOSYL (1 3)GALACTOSE; GALACTOSYL-(1-3)GALACTOSE;

ANTIBODY DEPLETION; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; BABOON; BOLUS INJECTION; CONTROLLED STUDY; IMMUNOADSORPTION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; PAPIO;

ANIMALS; DISACCHARIDES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; GALACTOSE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INJECTIONS, INTRAVENOUS; PAPIO; POLYLYSINE; TRISACCHARIDES;

EID: 1442314155     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1399-3089.2003.00096.x     Document Type: Article

References (19)

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