Evidence for a type 1 diabetes susceptibility locus (IDDM10) on chromosome 10p11-q11 in a Russian population

Scandinavian Journal of Immunology

Volumn 60, Issue 3, 2004, Pages 316-323

  Chistiakov, D A ^a   Seryogin, Y ^b   Savost'anov, K V ^b   Zilberman, L I ^c   Titovich, E V ^c   Kuraeva, T L ^c   Dedov, I I ^c   Nosikov, V V ^b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Department of Molecular Diagnostics   (Russian Federation)

^c N N BLOKHIN NATIONAL MEDICAL RESEARCH CENTER OF ONCOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

ARTICLE; CHROMOSOME 10P; CHROMOSOME 11; CHROMOSOME 11Q; CHROMOSOME ANALYSIS; CHROMOSOME MAP; CONTROLLED STUDY; GENE LOCUS; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; RUSSIAN FEDERATION; VENOUS BLOOD;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MALE; MICROSATELLITE REPEATS; POLYMORPHISM, GENETIC; RUSSIA;

EID: 4344619789     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0300-9475.2004.01480.x     Document Type: Article

References (30)

1. Field LL. Genetic linkage and association studies of type I diabetes: challenges and rewards. Diabetologia 2002;45:21-35.
2. Davies JL, Kawaguchi Y, Bennett ST et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994;37:130-6.
3. Reed P, Cucca F, Jenkins S et al. Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome region 10p11-q11. Hum Mol Genet 1997;6:1011-6.
4. Mein CA, Esposito L, Dunn MG et al. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat Genet 1998;19:297-300.
5. Johnson GCL, Koeleman BPC, Todd JA. Limitations of stratisfying sib-pair data in common disease linkage studies: An example using chromosome 10p14-10q11 in type 1 diabetes. Am J Med Genet 2002;113:158-66.
6. Concannon P, Gogolin-Ewens KJ. Hinds DA et al. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nat Genet 1998;19:292-6.
7. Nerup J, Pociot F, European Consortium for IDDM studies. A genome-wide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions. Am J Hum Genet 2001;69:1301-13.
8. Vaessen N, Heutink P, Houwing-Duistermaat JJ et al. A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands. Diabetes 2002;51:856-9.
9. National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979;28:1039-57.
10. Naserke HE, Dozio N, Ziegler A-G, Bonifacio E. Comparison of a novel microassay for insulin autoantibodies with the conventional radiobinding assay. Diabetologia 1998;41:681-3.
11. Petersen JS, Hejnaes KR, Moody A et al. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay. Diabetes 1994;43:459-67.
12. Kanai N, Fujii T, Saito K, Yokoyama T. Rapid and simple method for preparation of genomic DNA from easily obtainable clotted blood. J Clin Pathol 1994;47:1043-4.
13. Erlich H, Bugawan T, Begovich AB. HLA-DR, DQ and DP typing using PCR amplification and immobilized probes. Eur J Immunogenet 1991;18:33-5.
14. Boehncke WH, Loeliger C, Kuehnl P, Kalbacher H, Bohm BO, Gall H. Identification of HLA-DR and -DQ alleles conferring susceptibility to pollen allergy and pollen associated food allergy. Clin Exp Allergy 1998;28:434-41.
15. Kruglyak L, Daly ML, Reeve-Daly MP, Lander ES. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996;58:1347-63.
16. Broman BW, Murray JC, Sheffield VC, White RL, Weber JL. Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am J Hum Genet 1998;63:861-9.
17. Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11:241-7.
18. Spielman RS, McGinnis ME, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993; 52:506-16.
19. Zapata C, Carollo C, Rodriguez S. Sampling variance and distribution of the D′ measure of overall gametic disequlibrium between multiallelic loci. Ann Hum Genet 2001;65:395-406.
20. Cox NJ, Wapelhorst B, Morrison VA et al. Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 2001; 69:820-30.
21. Kaufman DL, Erlander MG, Clare-Salzler M, Atkinson MA, Maclaren MK, Tobin AJ. Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. J Clin Invest 1992;89:283-92.
22. Karlsen AE, Hagopian WA, Grubin CE. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acad Sci USA 1991;88: 8337-41.
23. Wapelhorst B, Bell B, Risch N, Spielman RS, Concannon P. Linkage and association studies in insulin-dependent diabetes mellitus with a new dinucleotide repeat polymorphism at the GAD65 locus. Autoimmunity 1995;21:127-30.
24. Rambrand R, Posiot F, Ronningen K, Nerup J, Michelsen BK. Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings: The Danish Study Group of Diabetes in Childhood. Hum Genet 1997;99:177-85.
25. Johnson GCL, Payne F, Nutland S et al. A comprehensive, statistically powered analysis of CAD2 in type 1 diabetes. Diabetes 2002;51:2866-70.
26. Schimpl A, Berberich I, Kneitz B et al. IL-2 and autoimmune disease. Cytokine Growth Factor Rev 2002;13:369-78.
27. Tenbrock K, Juang YT, Gourley MF et al. Antisense cyclic adenosine 5′-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus. J Immunol 2002;169:4147-52.
28. Inada A, Yamada Y, Someya Y et al. Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats. Biochem Biophys Res Commun 1998;253:712-8.
29. Yasui DH, Genetta T, Kadesch T et al. Transcriptional repression of the IL-2 gene in Th cells by ZEB. J Immunol 1998;160:4433-40.
30. Brabletz T, Jung A, Hlubek F et al. Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB. Int Immunol 1999;11:1701-8.