메뉴 건너뛰기




Volumn 16, Issue 5, 2004, Pages 522-526

Apoptosis and estrogen deficiency in primary Sjögren syndrome

Author keywords

Activation induced cell death; Apoptosis; Estrogen deficiency; Sj gren syndrome

Indexed keywords

ASPARTYLGLUTAMINYLVALYLASPARTIC ACID ALDEHYDE; AUTOANTIGEN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; EPITOPE; FAS ANTIGEN; FAS LIGAND; FODRIN; UNCLASSIFIED DRUG;

EID: 4344609041     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.bor.0000135450.78047.78     Document Type: Review
Times cited : (37)

References (58)
  • 1
    • 0027362950 scopus 로고
    • Self-nonself discrimination and tolerance in T and B lymphocytes
    • Miller JF: Self-nonself discrimination and tolerance in T and B lymphocytes. Immunol Res 1993, 12:115-130.
    • (1993) Immunol Res , vol.12 , pp. 115-130
    • Miller, J.F.1
  • 2
    • 0036533552 scopus 로고    scopus 로고
    • Autoreactive T cells revealed in the normal repertoire: Escape from negative selection and peripheral tolerance
    • Yan J, Mamula MJ: Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance. J Immunol 2002, 168:3188-3194.
    • (2002) J Immunol , vol.168 , pp. 3188-3194
    • Yan, J.1    Mamula, M.J.2
  • 5
    • 0026082028 scopus 로고
    • Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen
    • Chan EK, Hamel JC, Buyon JP, et al.: Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest 1991, 87:68-76.
    • (1991) J Clin Invest , vol.87 , pp. 68-76
    • Chan, E.K.1    Hamel, J.C.2    Buyon, J.P.3
  • 6
    • 0030973104 scopus 로고    scopus 로고
    • Direct ex vivo analysis of activated, Fas-sensitive autoreactive T cells in human autoimmune disease
    • Bieganowska KD, Ausubel LJ, Modabber Y, et al.: Direct ex vivo analysis of activated, Fas-sensitive autoreactive T cells in human autoimmune disease. J Exp Med 1997, 185:1585-1594.
    • (1997) J Exp Med , vol.185 , pp. 1585-1594
    • Bieganowska, K.D.1    Ausubel, L.J.2    Modabber, Y.3
  • 7
    • 0029866102 scopus 로고    scopus 로고
    • Surface blebs on apoptotic cells are sites of enhanced procoagulant activity implications for coagulation events and antigenic spread in systemic lupus erythematosus
    • Casciola-Rosen L, Rosen A, Petri M, et al.: Surface blebs on apoptotic cells are sites of enhanced procoagulant activity implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci USA 1996, 93:1624-1629.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1624-1629
    • Casciola-Rosen, L.1    Rosen, A.2    Petri, M.3
  • 8
    • 0034327194 scopus 로고    scopus 로고
    • Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages
    • Miranda-Carus ME, Askanase AD, Clancy RM, et al.: Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages. J Immunol 2000, 165:5345-5351.
    • (2000) J Immunol , vol.165 , pp. 5345-5351
    • Miranda-Carus, M.E.1    Askanase, A.D.2    Clancy, R.M.3
  • 9
    • 0030891492 scopus 로고    scopus 로고
    • Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus
    • Utz PJ, Hottelet M, Schur PH, et al.: Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus. J Exp Med 1997, 185:843-854.
    • (1997) J Exp Med , vol.185 , pp. 843-854
    • Utz, P.J.1    Hottelet, M.2    Schur, P.H.3
  • 10
    • 0033026546 scopus 로고    scopus 로고
    • The role of apoptosis in the initiation of the autoimmune response in Sjögren's syndrome
    • Humpherys-Beher MG, Peck AB, Dang H, et al.: The role of apoptosis in the initiation of the autoimmune response in Sjögren's syndrome. Clin Exp Immunol 1999, 116:383-387.
    • (1999) Clin Exp Immunol , vol.116 , pp. 383-387
    • Humpherys-Beher, M.G.1    Peck, A.B.2    Dang, H.3
  • 11
    • 0031004645 scopus 로고    scopus 로고
    • Rheumatic disease in an MRL strain of mice with a deficit in functional Fas ligand
    • Ito M, Terasaki S, Itoh J, et al.: Rheumatic disease in an MRL strain of mice with a deficit in functional Fas ligand. Arthritis Rheum 1997, 40:1054-1063.
    • (1997) Arthritis Rheum , vol.40 , pp. 1054-1063
    • Ito, M.1    Terasaki, S.2    Itoh, J.3
  • 12
    • 0029822182 scopus 로고    scopus 로고
    • A possible involvement of Fas-Fas ligand signaling in the pathogenesis of murine autoimmune gastritis
    • Nishio A, Katakai T, Oshima C, et al.: A possible involvement of Fas-Fas ligand signaling in the pathogenesis of murine autoimmune gastritis. Gastroenterology 1996, 111:956-967.
    • (1996) Gastroenterology , vol.111 , pp. 956-967
    • Nishio, A.1    Katakai, T.2    Oshima, C.3
  • 13
    • 0031034933 scopus 로고    scopus 로고
    • Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
    • Giordano C, Stassi G, De Maria R, et al.: Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science 1997, 275:960-963.
    • (1997) Science , vol.275 , pp. 960-963
    • Giordano, C.1    Stassi, G.2    De Maria, R.3
  • 14
    • 0141993915 scopus 로고    scopus 로고
    • Effective destruction of Fas-deficient insulin-producing β cells in type I diabetes
    • Apostolou I, Hao Z, Rajewsky K: et al.: Effective destruction of Fas-deficient insulin-producing β cells in type I diabetes. J Exp Med 2003, 198:1103-1106.
    • (2003) J Exp Med , vol.198 , pp. 1103-1106
    • Apostolou, I.1    Hao, Z.2    Rajewsky, K.3
  • 15
    • 1942475188 scopus 로고    scopus 로고
    • Autoimmune diabetes in the NOD mouse: An essential role of Fas-FasL signaling in β cell apoptosis
    • Silva DG, Socha L, Charlton B, et al.: Autoimmune diabetes in the NOD mouse: an essential role of Fas-FasL signaling in β cell apoptosis. Ann NY Acad Sci 2003, 1005:161-165. The study demonstrated that, in the presence of an inflammatory infiltrate, FasL-expressing β cells are exquisitely sensitive to Fas-mediated apoptosis and that this can be blocked by preventing FasL-Fas interaction.
    • (2003) Ann NY Acad Sci , vol.1005 , pp. 161-165
    • Silva, D.G.1    Socha, L.2    Charlton, B.3
  • 16
    • 0031028533 scopus 로고    scopus 로고
    • Fas and Fas ligand expression in salivary glands of patients with primary Sjögren syndrome
    • Kong L, Ogawa N, Nakabayashi T, et al.: Fas and Fas ligand expression in salivary glands of patients with primary Sjögren syndrome. Arthritis Rheum 1997, 40:87-97.
    • (1997) Arthritis Rheum , vol.40 , pp. 87-97
    • Kong, L.1    Ogawa, N.2    Nakabayashi, T.3
  • 17
    • 0030999866 scopus 로고    scopus 로고
    • Identification of α-fodrin as a candidate autoantigen in primary Sjögren's syndrome
    • Haneji N, Nakamura T, Takio K, et al.: Identification of α-fodrin as a candidate autoantigen in primary Sjögren's syndrome. Science 1997, 276:604-607.
    • (1997) Science , vol.276 , pp. 604-607
    • Haneji, N.1    Nakamura, T.2    Takio, K.3
  • 18
    • 0024573939 scopus 로고
    • Characterization of the calmodulin-binding site of nonerythroid α-spectrin
    • Leto TL, Pleasic S, Forget BG, et al.: Characterization of the calmodulin-binding site of nonerythroid α-spectrin. J Biol Chem 1989, 264:5826-5830.
    • (1989) J Biol Chem , vol.264 , pp. 5826-5830
    • Leto, T.L.1    Pleasic, S.2    Forget, B.G.3
  • 19
    • 0029802815 scopus 로고    scopus 로고
    • Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity
    • Martin SD, Finucane DM, Amarante-Mendes GP, et al.: Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J Biol Chem 1996, 271:28753-28753.
    • (1996) J Biol Chem , vol.271 , pp. 28753-28753
    • Martin, S.D.1    Finucane, D.M.2    Amarante-Mendes, G.P.3
  • 20
    • 10544238107 scopus 로고    scopus 로고
    • Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis
    • Vanags DM, Pörn-Ares I, Coppolaa S, et al: Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem 1996, 271:31075-31085.
    • (1996) J Biol Chem , vol.271 , pp. 31075-31085
    • Vanags, D.M.1    Pörn-Ares, I.2    Coppolaa, S.3
  • 21
    • 0032546795 scopus 로고    scopus 로고
    • Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
    • Janicke RU, Sprengart ML, Porter AG: Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J Biol Chem 1998, 273:15540-15545.
    • (1998) J Biol Chem , vol.273 , pp. 15540-15545
    • Janicke, R.U.1    Sprengart, M.L.2    Porter, A.G.3
  • 22
    • 0034762759 scopus 로고    scopus 로고
    • Novel fragments of the Sjögren's syndrome autoantigens α-fodrin and type 3 muscarinic acetylcholine receptor generated during cytotoxic lymphocyte granule- induced cell death
    • Nagaraju K, Cox A, Caciola-Rosen L, et al.: Novel fragments of the Sjögren's syndrome autoantigens α-fodrin and type 3 muscarinic acetylcholine receptor generated during cytotoxic lymphocyte granule- induced cell death. Arthritis Rheum 2001, 44:2376-2386.
    • (2001) Arthritis Rheum , vol.44 , pp. 2376-2386
    • Nagaraju, K.1    Cox, A.2    Caciola-Rosen, L.3
  • 23
    • 0037100407 scopus 로고    scopus 로고
    • Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjögren's syndrome
    • Saegusa K, Ishimaru N, Yanagi K, et al.: Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjögren's syndrome. J Immunol 2002, 169:1050-1057.
    • (2002) J Immunol , vol.169 , pp. 1050-1057
    • Saegusa, K.1    Ishimaru, N.2    Yanagi, K.3
  • 24
    • 0028990666 scopus 로고
    • Mechanism and biological significance of CD4- mediated cytotoxicity
    • Hahn S, Gehri R, Erb P: Mechanism and biological significance of CD4- mediated cytotoxicity. Immunol Rev 1995, 146:57-79.
    • (1995) Immunol Rev , vol.146 , pp. 57-79
    • Hahn, S.1    Gehri, R.2    Erb, P.3
  • 25
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • Rudel T, Bokoch GM: Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 1997, 276:1571-1574.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 26
    • 0030812347 scopus 로고    scopus 로고
    • Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6β
    • Huang S, Jiang Y, Li Z, et al.: Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6β. Immunity 1997, 6:739.
    • (1997) Immunity , vol.6 , pp. 739
    • Huang, S.1    Jiang, Y.2    Li, Z.3
  • 27
    • 0028990125 scopus 로고
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
    • Tewan M, Quan LT, O'Rouker K, et al.: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 1995, 81:801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewan, M.1    Quan, L.T.2    O'Rouker, K.3
  • 28
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • Casciola-Rosen L, Nicholson DW, Chong T, et al.: Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J Exp Med 1996, 183:1957-1964.
    • (1996) J Exp Med , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3
  • 29
    • 0028983657 scopus 로고
    • Cell-autonomous Fas(CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner T, Mogil RJ, LaFace D, et al.: Cell-autonomous Fas(CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995, 373:441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1    Mogil, R.J.2    LaFace, D.3
  • 30
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267:1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 31
    • 1942454327 scopus 로고    scopus 로고
    • Human lupus T cells resist inactivation and escape death by upregulating COX-2
    • doi: 10.1038/nm1005
    • Xu L, Zhang L, Kang HK, et al: Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat Med [serial online] 2004, doi: 10.1038/nm1005. Recent article demonstrates that activated T cells of lupus patients resist anergy and apoptosis by markedly upregulating and sustaining cyclooxygenase-2 (COX-21 expression. Studies with COX-2 inhibitors and Cox-2-deficient mice confirmed that this COX-2/FLIP antiapoptosis program is used selectively by anergy-resistant lupus T cells. It was also found that only COX-2 inhibitors were able to suppress the production of pathogenic autoantibodies to DNA by causing autoimmune T cell apoptosis.
    • (2004) Nat Med [Serial Online]
    • Xu, L.1    Zhang, L.2    Kang, H.K.3
  • 32
    • 0027490727 scopus 로고
    • + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL-lpr/lpr
    • + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL-lpr/lpr. Proc Natl Acad Sci USA 1993, 90:10340-10344.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10340-10344
    • Drappa, J.1    Brot, N.2    Elkon, K.B.3
  • 33
    • 0035889899 scopus 로고    scopus 로고
    • Possible role of organ-specific autoantigen for Fas ligand-mediated activation-induced cell death (AICD) in murine Sjögren's syndrome
    • Ishimaru N, Yanagi K, Ogawa K, et al.: Possible role of organ-specific autoantigen for Fas ligand-mediated activation-induced cell death (AICD) in murine Sjögren's syndrome. J Immunol 2001, 167:6031-6037.
    • (2001) J Immunol , vol.167 , pp. 6031-6037
    • Ishimaru, N.1    Yanagi, K.2    Ogawa, K.3
  • 34
    • 0028670381 scopus 로고
    • Antigen-induced death of mature T lymphocytes: Analysis by flow cytometry
    • Kabelitz D, Oberg H-H, Pohl T, et al.: Antigen-induced death of mature T lymphocytes: analysis by flow cytometry. Immunol Rev 1994, 142:157-174.
    • (1994) Immunol Rev , vol.142 , pp. 157-174
    • Kabelitz, D.1    Oberg, H.-H.2    Pohl, T.3
  • 35
    • 0029031043 scopus 로고
    • Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals
    • Pelfrey CM, Tranquill LR, Boehme SA, et al.: Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals. J Immunol 1995, 154:6191-6202.
    • (1995) J Immunol , vol.154 , pp. 6191-6202
    • Pelfrey, C.M.1    Tranquill, L.R.2    Boehme, S.A.3
  • 36
    • 0029025441 scopus 로고
    • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
    • Fisher GH, Rosenberg FJ, Strauss SE, et al.: Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995, 81:935-946.
    • (1995) Cell , vol.81 , pp. 935-946
    • Fisher, G.H.1    Rosenberg, F.J.2    Strauss, S.E.3
  • 37
    • 0033571645 scopus 로고    scopus 로고
    • Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines
    • Finnegan A, Mikecz K, Tao P, et al.: Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines. J Immunol 1999, 163:5383-5390.
    • (1999) J Immunol , vol.163 , pp. 5383-5390
    • Finnegan, A.1    Mikecz, K.2    Tao, P.3
  • 38
    • 0021993854 scopus 로고
    • Sex steroids and the rheumatic diseases
    • Lahita RG: Sex steroids and the rheumatic diseases. Arthritis Rheum 1985, 28:121-126.
    • (1985) Arthritis Rheum , vol.28 , pp. 121-126
    • Lahita, R.G.1
  • 39
    • 0024319605 scopus 로고
    • The immune-hypothalamic-pituitary-adrenal axis
    • Bateman A, Singh A, Krai T: The immune-hypothalamic-pituitary-adrenal axis. Endocrinol Rev 1989, 10:92-112.
    • (1989) Endocrinol Rev , vol.10 , pp. 92-112
    • Bateman, A.1    Singh, A.2    Krai, T.3
  • 40
    • 0020323594 scopus 로고
    • Estrogen metabolism in systemic lupus erythematosus: Patients and family members
    • Lahita RG, Bradlow L, Fishman J, et al.: Estrogen metabolism in systemic lupus erythematosus: patients and family members. Arthritis Rheum 1982, 25:843-846.
    • (1982) Arthritis Rheum , vol.25 , pp. 843-846
    • Lahita, R.G.1    Bradlow, L.2    Fishman, J.3
  • 41
    • 0028298948 scopus 로고
    • Association of patients of labial salivary gland inflammation with keratoconjunctivitis sicca. Analysis of 618 patients with suspected Sjögren's syndrome
    • Daniels T, Whitcher JP: Association of patients of labial salivary gland inflammation with keratoconjunctivitis sicca. Analysis of 618 patients with suspected Sjögren's syndrome. Arthritis Rheum 1994, 37:869-877.
    • (1994) Arthritis Rheum , vol.37 , pp. 869-877
    • Daniels, T.1    Whitcher, J.P.2
  • 42
    • 0010010107 scopus 로고    scopus 로고
    • Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency
    • Ishimi Y, Miyaura C, Ohmura M, et al.: Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency. Endocrinology 1999, 140:1893-1900.
    • (1999) Endocrinology , vol.140 , pp. 1893-1900
    • Ishimi, Y.1    Miyaura, C.2    Ohmura, M.3
  • 43
    • 0028070867 scopus 로고
    • Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow
    • Masuzawa T, Miyaura C, Onoe Y, et al.: Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow. J Clin Invest 1994, 94:1090-1097.
    • (1994) J Clin Invest , vol.94 , pp. 1090-1097
    • Masuzawa, T.1    Miyaura, C.2    Onoe, Y.3
  • 44
    • 0037220644 scopus 로고    scopus 로고
    • Interaction of the estrogen receptors with the Fas ligand promotor in human monocytes
    • Mor G, Sapi E, Abrahams VM, et al.: Interaction of the estrogen receptors with the Fas ligand promotor in human monocytes. J Immunol 2003, 170:114-122.
    • (2003) J Immunol , vol.170 , pp. 114-122
    • Mor, G.1    Sapi, E.2    Abrahams, V.M.3
  • 45
    • 0032983452 scopus 로고    scopus 로고
    • Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjögren's syndrome through Fas-mediated apoptosis
    • Ishimaru N, Saegusa K, Yanagi K, et al.: Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjögren's syndrome through Fas-mediated apoptosis. Am J Pathol 1999, 155:173-181.
    • (1999) Am J Pathol , vol.155 , pp. 173-181
    • Ishimaru, N.1    Saegusa, K.2    Yanagi, K.3
  • 46
    • 0026001659 scopus 로고
    • Estrogen regulates the IFN-γ promoter
    • Fox HS, Bond BL, Parslow TG: Estrogen regulates the IFN-γ promoter. J Immunol 1991, 146:4362-4367.
    • (1991) J Immunol , vol.146 , pp. 4362-4367
    • Fox, H.S.1    Bond, B.L.2    Parslow, T.G.3
  • 47
    • 0029810082 scopus 로고    scopus 로고
    • Hormone-induced apoptosis by Fas-nuclear receptor fusion protein: Novel biological tools for controlling apoptosis in vivo
    • Takabayashi H, Oida H, Fujisawa K, et al.: Hormone-induced apoptosis by Fas-nuclear receptor fusion protein: novel biological tools for controlling apoptosis in vivo. Cancer Res 1996, 56:4164-4170.
    • (1996) Cancer Res , vol.56 , pp. 4164-4170
    • Takabayashi, H.1    Oida, H.2    Fujisawa, K.3
  • 48
    • 0030901474 scopus 로고    scopus 로고
    • Estrogen-receptor-mediated inhibition of human endothelial cell apoptosis. Estradiol as a survival factor
    • Spyridopoulos I, Sullivan A, Kearney M, et al.: Estrogen-receptor- mediated inhibition of human endothelial cell apoptosis. Estradiol as a survival factor. Circulation 1997, 95:1505-1514.
    • (1997) Circulation , vol.95 , pp. 1505-1514
    • Spyridopoulos, I.1    Sullivan, A.2    Kearney, M.3
  • 49
    • 0034606788 scopus 로고    scopus 로고
    • 17β-Estradiol prevents programmed cell death in cardiac myocytes
    • Pelzer T, Schumann M, Neumann M, et al.: 17β-Estradiol prevents programmed cell death in cardiac myocytes. Biochem Biophys Res Commun 2000, 268:192-200.
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 192-200
    • Pelzer, T.1    Schumann, M.2    Neumann, M.3
  • 50
    • 0022374305 scopus 로고
    • Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action
    • Ansar-Ahmed S, Penhale WJ, Talal N: Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action. Am J Pathol 1985, 121:531-551.
    • (1985) Am J Pathol , vol.121 , pp. 531-551
    • Ansar-Ahmed, S.1    Penhale, W.J.2    Talal, N.3
  • 53
    • 0029802660 scopus 로고    scopus 로고
    • Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1 and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production
    • Kimble RB, Srivastava S, Ross FP, et al.: Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1 and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production. J Biol Chem 1996, 271:28890-28897.
    • (1996) J Biol Chem , vol.271 , pp. 28890-28897
    • Kimble, R.B.1    Srivastava, S.2    Ross, F.P.3
  • 54
    • 0141425633 scopus 로고    scopus 로고
    • Development of autoimmune exocrinopathy resembling Sjögren's syndrome in estrogen-deficient mice of healthy background
    • Ishimaru N, Arakaki R, Watanabe M, et al.: Development of autoimmune exocrinopathy resembling Sjögren's syndrome in estrogen-deficient mice of healthy background. Am J Pathol 2003, 163:1481-1490. This study evaluated the effects on autoantigen cleavage in estrogen-deficient healthy C57BL/6 (B6) mice treated with an ovariectomy. A significant increase in apoptotic epithelial salivary gland cells was associated with α-fodrin cleavage. A cleavage product of 120-kDa α-fodrin was detected in salivary gland cells that had undergone tamoxifen-induced apoptosis through caspase activation, especially caspase-1. Adoptive transfer of α-fodrin-reactive T cells into ovariectomized B6 mice resulted in the development of autoimmune exocrinopathy quite similar to Sjögren syndrome.
    • (2003) Am J Pathol , vol.163 , pp. 1481-1490
    • Ishimaru, N.1    Arakaki, R.2    Watanabe, M.3
  • 55
    • 0037134793 scopus 로고    scopus 로고
    • Estrogens prevents calcium-induced release of cytochrome c from heart mitochondria
    • Morkuniene R, Jekabsone A, Borutaite V: Estrogens prevents calcium-induced release of cytochrome c from heart mitochondria. FEBS Lett 2002, 521:53-56.
    • (2002) FEBS Lett , vol.521 , pp. 53-56
    • Morkuniene, R.1    Jekabsone, A.2    Borutaite, V.3
  • 56
    • 0029360415 scopus 로고
    • The death domain: A module shared by proteins with diverse cellular function
    • Feinstein E, Kimchi A, Wallach D, et al.: The death domain: a module shared by proteins with diverse cellular function. Trends Biochem Sci 1995, 20:342-344.
    • (1995) Trends Biochem Sci , vol.20 , pp. 342-344
    • Feinstein, E.1    Kimchi, A.2    Wallach, D.3
  • 57
    • 0030891312 scopus 로고    scopus 로고
    • A protein factor that inhibits ATP-dependent glutamate and γ-aminobutyric acid accumulation into synaptic vesicles: Purification and initial characterization
    • Ozkan ED, Lee FS, Ueda T: A protein factor that inhibits ATP-dependent glutamate and γ-aminobutyric acid accumulation into synaptic vesicles: purification and initial characterization. Proc Natl Acad Sci USA 1997, 94:4137-4142.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4137-4142
    • Ozkan, E.D.1    Lee, F.S.2    Ueda, T.3
  • 58
    • 0035879352 scopus 로고    scopus 로고
    • Integration of human T lymphocyte cytoskeleton by cytolinker protein
    • Brown MJ, Hallam JA, Yamada KM, et al.: Integration of human T lymphocyte cytoskeleton by cytolinker protein. J Immunol 2001, 167:641-645.
    • (2001) J Immunol , vol.167 , pp. 641-645
    • Brown, M.J.1    Hallam, J.A.2    Yamada, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.