Rheumatic diseases in an MRL strain of mice with a deficit in the functional Fas ligand

Arthritis and Rheumatism

Volumn 40, Issue 6, 1997, Pages 1054-1063

  Ito, Mituko R ^a   Terasaki, Shizuko ^a   Itoh, Junpei ^b   Katoh, Hideki ^c   Yonehara, Shin ^d   Nose, Masato ^a,e  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIPPON KAYAKU CO LTD   (Japan)

^c CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; FLOW CYTOMETRY; IMMUNE RESPONSE; LIGAND BINDING; LYMPHOID CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RHEUMATIC DISEASE;

ANIMALS; ANTIBODIES; ANTIBODIES, ANTINUCLEAR; ANTIGENS, CD95; APOPTOSIS; ARTHRITIS; CAENORHABDITIS ELEGANS PROTEINS; CD4-CD8 RATIO; DNA, SINGLE-STRANDED; FAS LIGAND PROTEIN; FEMALE; GLOMERULONEPHRITIS; HELMINTH PROTEINS; IMMUNOGLOBULIN G; LYMPHOID TISSUE; LYMPHOPROLIFERATIVE DISORDERS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED MRL LPR; RHEUMATIC DISEASES; UP-REGULATION; VASCULITIS;

EID: 0031004645     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400610     Document Type: Article

References (29)

1. Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756, 1989
2. Nagata S: Fas and Fas ligand: a death factor and its receptor. Adv Immunol 57:129-144, 1995
3. Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S: Expression of the Fas ligand in cells of T cell lineage. J Immunol 154:3806-3813, 1996
4. Dhein J, Walczak H, Baumler C, Debatin K-M, Krammer PH: Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373:438-441, 1995
5. Ashany D, Lacy E, Nicolic-Zugic J, Friedman SM, Elkon KB: Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway. Proc Natl Acad Sci U S A 92:11225-11229, 1995
6. Rathmell JC, Cooke MP, Ho WY, Grein J, Townsend SE, Davis MM, Goodnow CC: CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature 376:181-184, 1995
7. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S: Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976, 1994
8. Murphy ED, Roths JB: Autoimmunity and lymphoproliferation: induction by mutant gene 1pr, and acceleration by a male-associated factor in strain BXSB mice. In, Genetic Control of Autoimmune Disease. Edited by NR Rose, PE Bigazzi, NL Werner. New York, Elsevier North Holland Inc., 1979
9. Andrews BS, Eisenberg RA, Theofilopoulos AN, Izui S, Wilson CB, McConahey PJ, Murphy ED, Roths JB, Dixon FJ: Spontaneous murine lupus-like syndromes: clinical and immunopathological manifestations in several strains. J Exp Med 148:1198-1215, 1978
10. Nose M, Nishimura M, Kyogoku M: Analysis of granulomatous arteritis in MRL/Mp autoimmune disease mice bearing lympho-proliferative genes: the use of mouse genetics to dissociate the development of arteritis and glomerulonephritis. Am J Pathol 135:271-280, 1989
11. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S: Lymphuproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317, 1992
12. Adachi M, Suematsu S, Kondo T, Ogasawara J, Tanaka T, Yoshida N, Nagata S: Targeted mutation in Fas gene causes hyperplasia in peripheral lymphoid organs and liver. Nature Genet 11:294-300, 1995
13. Adachi M, Suematsu S, Suda T, Watanabe D, Fukuyama H, Ogasawara J, Tanaka T, Yoshida N, Nagata S: Enhanced and accelerated lymphoproliferation in Fas-null mice. Proc Natl Acad Sci U S A 93:2131-2136, 1996
14. Roths JB, Murphy ED, Eicher EM: A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice. J Exp Med 159:1-20, 1984
15. Davidson WF, Dumont FJ, Bedigian HG, Fowlkes BJ, Morse HC III: Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. J Immunol 136:4075-4085, 1986
16. Nose M, Kato M, Okada N, Kyogoku M, Okada H: Tissue distribution of HRF20, a novel factor preventing the membrane attack of homologous complement, and its predominant expression on endothelial cells in vivo. Immunology 70:145-149, 1990
17. Ho MK, Springer TA: Mac-2, a novel 32,000 Mr mouse membrane macrophage subpopulation-specific antigen defined by monoclonal antibodies. J Immunol 128:1221-1228, 1982
18. Barondes SH, Castronovo V, Cooper DNW, Cummings RD, Drickamer K, Feizi T, Gitt MA, Hirabayashi J, Hughes C, Kasai K-I, Leffler H, Liu F-T, Lotan R, Mercurio AM, Monsigny M, Pillai S, Poirer F, Raz A, Rigby PWJ, Rini JM, Wang JL: Galactins: a family of animal β-galactoside-binding lectins. Cell 76:597-598, 1994
19. McLane IW, Nakane PK: Periodate-lysine-paraformaldehyde fixative: a new fixative for immunoelectron microscopy. J Immunol 128:1077-1083, 1982
20. Takahashi S, Nose M, Sasaki J, Yamamoto T, Kyogoku M: IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis. J Immunol 147:515-520, 1991
21. Zheng L, Fisher G, Miller RE, Peschon J, Lynch DH, Lenardo MJ: Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 377:348-351, 1995
22. Cohen PL, Eisenberg RA: Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1:243-269, 1991
23. Izui S, Kekkey VE, Masuda K, Yoshida H, Roths JB, Murphy ED: Induction of various autoantibodies by mutant gene lpr in several strains of mice. J Immunol 133:227-233, 1984
24. Mariani SM, Matiba B, Armondola EA, Krammer PH: The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice. Eur J Immunol 24:3119-3123, 1994
25. Davidson WF, Calkins C, Hugin A, Giese T, Holmes KL: Cytokine secretion by C3H-lpr and -gld T cells: hypersecretion of IFN-γ and tumor necrosis factor-α by stimulated CD4+ T cells. J Immunol 146:4138-4148, 1991
26. Onel KB, Tucek-Szabo CL, Ashany D, Nikolic-Zugic J, Elkon KB: Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell ontogeny. Eur J Immunol 25:2940-2947, 1995
27. Wang J, Taniuchi I, Maekawa Y, Howard M, Cooper MD, Watanabe T: Expression and function of Fas antigen on activated murine B cells. Eur J Immunol 26:92-96, 1996
28. Allen RD, Marshall JD, Roths JB, Sidman CL: Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules. J Exp Med 172:1367-1375, 1990
29. Chu JL, Ramos P, Rosendorff A, Nikolic-Zugic J, Lacy E, Matsuzawa A, Elkon KB: Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome. J Exp Med 181:393-398, 1995