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Volumn 121, Issue 7, 2008, Pages 1025-1035

Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling

Author keywords

Clostridial toxins; Epithelial junctions; Gene expression

Indexed keywords

ACTIN; CALCIUM ION; CELL PROTEIN; CYTOTOXIN; G ACTIN; MEMBRANE PROTEIN; MONOMER; MYOSIN ADENOSINE TRIPHOSPHATASE; PROTEIN MAL; PROTEIN ROCK; RAC PROTEIN; RAC1 PROTEIN; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERUM RESPONSE FACTOR; UVOMORULIN;

EID: 43149111791     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.014456     Document Type: Article
Times cited : (78)

References (59)
  • 1
    • 0032476590 scopus 로고    scopus 로고
    • Serum response factor is essential for mesoderm formation during mouse embryogenesis
    • Arsenian, S., Weinhold, B., Oelgeschlager, M., Rather, U. and Nordheim, A. (1998). Serum response factor is essential for mesoderm formation during mouse embryogenesis. EMBO J. 17, 6289-6299.
    • (1998) EMBO J , vol.17 , pp. 6289-6299
    • Arsenian, S.1    Weinhold, B.2    Oelgeschlager, M.3    Rather, U.4    Nordheim, A.5
  • 2
    • 27844507514 scopus 로고    scopus 로고
    • E-cadherin endocytosis regulates the activity of Rap1: A traffic light GTPase at the crossroads between cadherin and integrin function
    • Balzac, F., Avolio, M., Degani, S., Kaverina, L, Torti, M., Silengo, L., Small, J. V. and Retta, S. F. (2005). E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function. J. Cell Sci. 118, 4765-4783.
    • (2005) J. Cell Sci , vol.118 , pp. 4765-4783
    • Balzac, F.1    Avolio, M.2    Degani, S.3    Kaverina, L.4    Torti, M.5    Silengo, L.6    Small, J.V.7    Retta, S.F.8
  • 3
    • 24644519086 scopus 로고    scopus 로고
    • The challenges of abundance: Epithelial junctions and small GTPase signalling
    • Braga, V. M. and Yap, A. S. (2005). The challenges of abundance: epithelial junctions and small GTPase signalling. Curr. Opin. Cell Biol. 17, 466-474.
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 466-474
    • Braga, V.M.1    Yap, A.S.2
  • 4
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga, V. M., Machesky, L. M., Hall, A. and Hotchin, N. A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
    • (1997) J. Cell Biol , vol.137 , pp. 1421-1431
    • Braga, V.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 5
    • 0016800815 scopus 로고
    • Improved methods for reducing calcium and magnesium concentrations in tissue culture medium: Application to studies of lymphoblast proliferation in vitro
    • Brennan, J. K., Mansky, J., Roberts, G. and Lichtman, M. A. (1975). Improved methods for reducing calcium and magnesium concentrations in tissue culture medium: application to studies of lymphoblast proliferation in vitro. In Vitro 11, 354-360.
    • (1975) In Vitro , vol.11 , pp. 354-360
    • Brennan, J.K.1    Mansky, J.2    Roberts, G.3    Lichtman, M.A.4
  • 6
    • 33846065117 scopus 로고    scopus 로고
    • Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells
    • Capaido, C. T. and Macara, I. G. (2007). Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Mol. Biol. Cell 18, 189-200.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 189-200
    • Capaido, C.T.1    Macara, I.G.2
  • 7
    • 0037424238 scopus 로고    scopus 로고
    • R-Ras glucosylation and transient RhoA activation determine the cytopathic effect produced by toxin B variants from toxin A-negative strains of Clostridium difficile
    • Chaves-Olarte, E., Freer, E., Parra, A., Guzman-Verri, C., Moreno, E. and Thelestam, M. (2003), R-Ras glucosylation and transient RhoA activation determine the cytopathic effect produced by toxin B variants from toxin A-negative strains of Clostridium difficile. J. Biol. Chem. 278, 7956-7963.
    • (2003) J. Biol. Chem , vol.278 , pp. 7956-7963
    • Chaves-Olarte, E.1    Freer, E.2    Parra, A.3    Guzman-Verri, C.4    Moreno, E.5    Thelestam, M.6
  • 8
    • 0036854328 scopus 로고    scopus 로고
    • The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization
    • Copeland, J. W. and Treisman, R. (2002). The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. Mol. Biol. Cell 13, 4088-4099.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4088-4099
    • Copeland, J.W.1    Treisman, R.2
  • 10
    • 28344439885 scopus 로고    scopus 로고
    • Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly
    • Drees, F., Pokutta, S., Yamada, S., Nelson, W. J. and Weis, W. I. (2005). Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell 123, 903-915.
    • (2005) Cell , vol.123 , pp. 903-915
    • Drees, F.1    Pokutta, S.2    Yamada, S.3    Nelson, W.J.4    Weis, W.I.5
  • 11
    • 2342423628 scopus 로고    scopus 로고
    • Megakaryoblasfic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells
    • Du, K. L., Chen, M., Li, J., Lepore, J. J., Mericko, P. and Parmacek, M. S. (2004). Megakaryoblasfic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells. J. Biol. Chem. 279, 17578-17586.
    • (2004) J. Biol. Chem , vol.279 , pp. 17578-17586
    • Du, K.L.1    Chen, M.2    Li, J.3    Lepore, J.J.4    Mericko, P.5    Parmacek, M.S.6
  • 13
    • 33645889655 scopus 로고    scopus 로고
    • Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways
    • Giannone, G. and Sheetz, M. P. (2006). Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. Trends Cell Biol. 16, 213-223.
    • (2006) Trends Cell Biol , vol.16 , pp. 213-223
    • Giannone, G.1    Sheetz, M.P.2
  • 14
    • 0035816691 scopus 로고    scopus 로고
    • Differential usage of signal transduction pathways defines two types of serum response factor target gene
    • Gineitis, D. and Treisman, R. (2001). Differential usage of signal transduction pathways defines two types of serum response factor target gene. J. Biol. Chem. 276, 24531-24539.
    • (2001) J. Biol. Chem , vol.276 , pp. 24531-24539
    • Gineitis, D.1    Treisman, R.2
  • 15
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert, S., Jechlinger, M. and Beug, H. (2003). Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat. Rev. Mol. Cell Biol. 4, 657-665.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 16
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • Gumbiner, B. M. (2005). Regulation of cadherin-mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 6, 622-634.
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 17
    • 0024095524 scopus 로고
    • The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
    • Gumbiner, B., Stevenson, B. and Grimaldi, A. (1988). The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J. Cell Biol. 107, 1575-1587.
    • (1988) J. Cell Biol , vol.107 , pp. 1575-1587
    • Gumbiner, B.1    Stevenson, B.2    Grimaldi, A.3
  • 18
    • 33845414010 scopus 로고    scopus 로고
    • Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis
    • Halbleib, J. M. and Nelson, W. J. (2006). Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev. 20, 3199-3214.
    • (2006) Genes Dev , vol.20 , pp. 3199-3214
    • Halbleib, J.M.1    Nelson, W.J.2
  • 19
    • 0028885538 scopus 로고
    • Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors
    • Hill, C. S. and Treisman, R. (1995). Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors. EMBO J. 14, 5037-5047.
    • (1995) EMBO J , vol.14 , pp. 5037-5047
    • Hill, C.S.1    Treisman, R.2
  • 20
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
    • Hill, C. S., Wynne, J. and Treisman, R. (1995). The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81, 1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 21
    • 33846807241 scopus 로고    scopus 로고
    • Difference in the cytotoxic effects of toxin B from Clostridiurn difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470
    • Huelsenbeck, J., Dreger, S., Gerhard, R., Barth, H., Just, I. and Genth, H. (2007). Difference in the cytotoxic effects of toxin B from Clostridiurn difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470. Infect. Immun. 75 801-809.
    • (2007) Infect. Immun , vol.75 , pp. 801-809
    • Huelsenbeck, J.1    Dreger, S.2    Gerhard, R.3    Barth, H.4    Just, I.5    Genth, H.6
  • 22
    • 2542424590 scopus 로고    scopus 로고
    • Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex
    • Ivanov, A. L, McCall, I. C., Parkos, C. A. and Nusrat, A. (2004). Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. Mol. Biol. Cell 15, 2639-2651.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2639-2651
    • Ivanov, A.L.1    McCall, I.C.2    Parkos, C.A.3    Nusrat, A.4
  • 23
    • 33751087736 scopus 로고    scopus 로고
    • Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin
    • Janda, E., Nevolo, M., Lehmann, K., Downward, J., Beug, H. and Grieco, M. (2006). Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene 25, 7117-7130.
    • (2006) Oncogene , vol.25 , pp. 7117-7130
    • Janda, E.1    Nevolo, M.2    Lehmann, K.3    Downward, J.4    Beug, H.5    Grieco, M.6
  • 24
    • 0032514214 scopus 로고    scopus 로고
    • Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity
    • Jou, T. S. and Nelson, W. J. (1998). Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity. J. Cell Biol. 142, 85-100.
    • (1998) J. Cell Biol , vol.142 , pp. 85-100
    • Jou, T.S.1    Nelson, W.J.2
  • 26
    • 33846847701 scopus 로고    scopus 로고
    • Rap1: A key regulator in cell-cell junction formation
    • Kooistra, M. R., Dube, N. and Bus, J. L. (2007). Rap1: a key regulator in cell-cell junction formation. J. Cell Sci. 120, 17-22.
    • (2007) J. Cell Sci , vol.120 , pp. 17-22
    • Kooistra, M.R.1    Dube, N.2    Bus, J.L.3
  • 27
    • 0028059290 scopus 로고
    • E-cadherin null mutant embryos fail to form a trophectoderm epithelium
    • Larue, L., Ohsugi, M., Hirchenhain, J. and Kemler, R. (1994). E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc. Natl. Acad. Sci. USA 91, 8263-8267.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8263-8267
    • Larue, L.1    Ohsugi, M.2    Hirchenhain, J.3    Kemler, R.4
  • 28
    • 21144455710 scopus 로고    scopus 로고
    • Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development
    • Li, J., Zhu, X., Chen, M., Cheng, L., Zhou, D., Lu, M. M., Du, K., Epstein, J. A. and Parmacek, M. S. (2005). Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc. Nad. Acad. Sci. USA 102, 8916-8921.
    • (2005) Proc. Nad. Acad. Sci. USA , vol.102 , pp. 8916-8921
    • Li, J.1    Zhu, X.2    Chen, M.3    Cheng, L.4    Zhou, D.5    Lu, M.M.6    Du, K.7    Epstein, J.A.8    Parmacek, M.S.9
  • 29
    • 33745170559 scopus 로고    scopus 로고
    • Requirement of a myocardin-related transcription factor for development of mammary myoepithehal cells
    • Li, S., Chang, S., Qi, X., Richardson, J. A. and Olson, E. N. (2006). Requirement of a myocardin-related transcription factor for development of mammary myoepithehal cells. Mol. Cell. Biol. 26, 5797-5808.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 5797-5808
    • Li, S.1    Chang, S.2    Qi, X.3    Richardson, J.A.4    Olson, E.N.5
  • 30
    • 0038556694 scopus 로고    scopus 로고
    • Tumor progression: Small GTPases and loss of cell-cell adhesion
    • Lozano, E., Belson, M. and Braga, V. M. (2003). Tumor progression: small GTPases and loss of cell-cell adhesion. BioEssays 25, 452-463.
    • (2003) BioEssays , vol.25 , pp. 452-463
    • Lozano, E.1    Belson, M.2    Braga, V.M.3
  • 31
    • 33745753386 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of Rac1-GTP during epithelia] cell scattering
    • Lynch, E. A., Stall, J., Schmidt, G., Chavrier, P. and D'Souza-Schorey, C. (2006). Proteasome-mediated degradation of Rac1-GTP during epithelia] cell scattering. Mol. Biol. Cell 17, 2236-2242.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2236-2242
    • Lynch, E.A.1    Stall, J.2    Schmidt, G.3    Chavrier, P.4    D'Souza-Schorey, C.5
  • 32
    • 0035808389 scopus 로고    scopus 로고
    • Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
    • Mack, C. P., Somlyo, A. V., Hautmann, M., Somlyo, A. P. and Owens, G. K. (2001). Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J. Biol. Chem. 276, 341-347.
    • (2001) J. Biol. Chem , vol.276 , pp. 341-347
    • Mack, C.P.1    Somlyo, A.V.2    Hautmann, M.3    Somlyo, A.P.4    Owens, G.K.5
  • 33
    • 9644274187 scopus 로고    scopus 로고
    • Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelia]-to-myofibroblast transition: Role for beta-catenin
    • Masszi, A., Fan, L., Rosivall, L., McCulloch, C. A., Rutstein, O. D., Mucsi, I. and Kapus, A. (2004). Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelia]-to-myofibroblast transition: role for beta-catenin. Am. J. Pathol. 165, 1955-1967.
    • (2004) Am. J. Pathol , vol.165 , pp. 1955-1967
    • Masszi, A.1    Fan, L.2    Rosivall, L.3    McCulloch, C.A.4    Rutstein, O.D.5    Mucsi, I.6    Kapus, A.7
  • 34
    • 0037336565 scopus 로고    scopus 로고
    • Signalling to and from tight junctions
    • Matter, K. and Balda, M. S. (2003). Signalling to and from tight junctions. Nat. Rev. Mol. Cell Biol. 4, 225-236.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 225-236
    • Matter, K.1    Balda, M.S.2
  • 35
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • Miralles, F., Posern, G., Zaromytidou, A. I. and Treisman, R. (2003). Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 113, 329-342.
    • (2003) Cell , vol.113 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.I.3    Treisman, R.4
  • 36
    • 33746038584 scopus 로고    scopus 로고
    • Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation
    • Miyake, Y., Inoue, N., Nishimura, K., Kinoshita, N., Hosoya, H. and Yonemura, S. (2006). Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation. Exp. Cell Res. 312, 1637-1650.
    • (2006) Exp. Cell Res , vol.312 , pp. 1637-1650
    • Miyake, Y.1    Inoue, N.2    Nishimura, K.3    Kinoshita, N.4    Hosoya, H.5    Yonemura, S.6
  • 37
    • 0023300801 scopus 로고
    • Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site
    • Mohun, T., Garrett, N. and Treisman, R. (1987). Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site. EMBO J. 6, 667-673.
    • (1987) EMBO J , vol.6 , pp. 667-673
    • Mohun, T.1    Garrett, N.2    Treisman, R.3
  • 38
    • 36849053911 scopus 로고    scopus 로고
    • Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling
    • Morita, T., Mayanagi, T. and Sobue, K. (2007). Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J. Cell Biol. 179, 1027-1042.
    • (2007) J. Cell Biol , vol.179 , pp. 1027-1042
    • Morita, T.1    Mayanagi, T.2    Sobue, K.3
  • 39
    • 0034994490 scopus 로고    scopus 로고
    • Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites
    • Nakagawa, M., Fukata, M., Yamaga, M., Itoh, N. and Kaibuchi, K. (2001). Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites. J. Cell Sci. 114, 1829-1838.
    • (2001) J. Cell Sci , vol.114 , pp. 1829-1838
    • Nakagawa, M.1    Fukata, M.2    Yamaga, M.3    Itoh, N.4    Kaibuchi, K.5
  • 40
  • 41
    • 27244437468 scopus 로고    scopus 로고
    • Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation
    • Oh, J., Richardson, J. A. and Olson, E. N. (2005). Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proc. Natl. Acad. Sci. USA 102, 15122-15127.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15122-15127
    • Oh, J.1    Richardson, J.A.2    Olson, E.N.3
  • 42
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl, A. K., Wilgenbus, P., Dahl, U., Semb, H. and Christofori, G. (1998). A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392, 190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 43
    • 0028093281 scopus 로고
    • Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding
    • Pokutta, S., Herrenknecht, K., Kemler, R. and Engel, J. (1994). Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur. J. Biochem. 223, 1019-1026.
    • (1994) Eur. J. Biochem , vol.223 , pp. 1019-1026
    • Pokutta, S.1    Herrenknecht, K.2    Kemler, R.3    Engel, J.4
  • 44
    • 33750343214 scopus 로고    scopus 로고
    • Actin' together: Serum response factor, its cofactors and the link to signal transduction
    • Posern, G. and Treisman, R. (2006). Actin' together: serum response factor, its cofactors and the link to signal transduction. Trends Cell Biol. 16, 588-596.
    • (2006) Trends Cell Biol , vol.16 , pp. 588-596
    • Posern, G.1    Treisman, R.2
  • 45
    • 0036906627 scopus 로고    scopus 로고
    • Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor
    • Posern, G., Sotiropoulos, A. and Treisman, R. (2002). Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor. Mol. Biol. Cell 13, 4167-4178.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4167-4178
    • Posern, G.1    Sotiropoulos, A.2    Treisman, R.3
  • 46
    • 8144229290 scopus 로고    scopus 로고
    • Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL
    • Posern, G., Miralles, F., Guettler, S. and Treisman, R. (2004). Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL. EMBO J. 23, 3973-3983.
    • (2004) EMBO J , vol.23 , pp. 3973-3983
    • Posern, G.1    Miralles, F.2    Guettler, S.3    Treisman, R.4
  • 47
    • 0033777071 scopus 로고    scopus 로고
    • Determination of GTP loading on Rho
    • Ren, X. D. and Schwartz, M. A. (2000). Determination of GTP loading on Rho. Meth. Enzymol. 325, 264-272.
    • (2000) Meth. Enzymol , vol.325 , pp. 264-272
    • Ren, X.D.1    Schwartz, M.A.2
  • 48
    • 0036305635 scopus 로고    scopus 로고
    • ROCK and Dia have opposing effects on adherens junctions downstream of Rho
    • Sahai, E. and Marshall, C. J. (2002). ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat. Cell Biol. 4, 408-415.
    • (2002) Nat. Cell Biol , vol.4 , pp. 408-415
    • Sahai, E.1    Marshall, C.J.2
  • 49
    • 32144454684 scopus 로고    scopus 로고
    • Purification of TAT-C3 exoenzyme
    • Sahai, E. and Olson, M. F. (2006). Purification of TAT-C3 exoenzyme. Meth. Enzymol. 406, 128-140.
    • (2006) Meth. Enzymol , vol.406 , pp. 128-140
    • Sahai, E.1    Olson, M.F.2
  • 50
    • 0032473351 scopus 로고    scopus 로고
    • RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation
    • Sahai, E., Alberts, A. S. and Treisman, R. (1998). RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. EMBO J. 17, 1350-1361.
    • (1998) EMBO J , vol.17 , pp. 1350-1361
    • Sahai, E.1    Alberts, A.S.2    Treisman, R.3
  • 51
    • 0033597825 scopus 로고    scopus 로고
    • Signal-regulated activation of serum response factor is mediated by changes in actin dynamics
    • Sotiropoulos, A., Gineitis, D., Copeland, J. and Treisman, R. (1999). Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell 98, 159-169.
    • (1999) Cell , vol.98 , pp. 159-169
    • Sotiropoulos, A.1    Gineitis, D.2    Copeland, J.3    Treisman, R.4
  • 53
    • 34250849566 scopus 로고    scopus 로고
    • Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL
    • Vartiainen, M. K., Guettler, S., Larijani, B. and Treisman, R. (2007). Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL. Science 316, 1749-1752.
    • (2007) Science , vol.316 , pp. 1749-1752
    • Vartiainen, M.K.1    Guettler, S.2    Larijani, B.3    Treisman, R.4
  • 54
    • 0034695656 scopus 로고    scopus 로고
    • Directed actin polymerization is the driving force for epithelia] cell-cell adhesion
    • Vasioukhin, V., Bauer, C., Yin, M. and Fuchs, E. (2000). Directed actin polymerization is the driving force for epithelia] cell-cell adhesion. Cell 100, 209-219.
    • (2000) Cell , vol.100 , pp. 209-219
    • Vasioukhin, V.1    Bauer, C.2    Yin, M.3    Fuchs, E.4
  • 55
    • 1842426910 scopus 로고    scopus 로고
    • Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration
    • Wells, C. M., Walmsley, M., Ooi, S., Tybulewicz, V. and Ridley, A. J. (2004). Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J. Cell Sci. 117, 1259-1268.
    • (2004) J. Cell Sci , vol.117 , pp. 1259-1268
    • Wells, C.M.1    Walmsley, M.2    Ooi, S.3    Tybulewicz, V.4    Ridley, A.J.5
  • 56
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer, J., Jung, C. K., Shackel, I. and Williams, P. M. (1999). Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal. Biochem. 270, 41-49.
    • (1999) Anal. Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 57
    • 28344433073 scopus 로고    scopus 로고
    • Deconstructing the cadherin-catenin-actin complex
    • Yamada, S., Pokutta, S., Drees, F., Weis, W. I. and Nelson, W. J. (2005). Deconstructing the cadherin-catenin-actin complex. Cell 123, 889-901.
    • (2005) Cell , vol.123 , pp. 889-901
    • Yamada, S.1    Pokutta, S.2    Drees, F.3    Weis, W.I.4    Nelson, W.J.5
  • 59
    • 0034658674 scopus 로고    scopus 로고
    • Oncogenic, Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
    • Zondag, G. C., Evers, E. E., ten Klooster, J. P., Janssen, L., van der Kammen, R. A. and Collard, J. G. (2000). Oncogenic, Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J. Cell Biol. 149, 775-782.
    • (2000) J. Cell Biol , vol.149 , pp. 775-782
    • Zondag, G.C.1    Evers, E.E.2    ten Klooster, J.P.3    Janssen, L.4    van der Kammen, R.A.5    Collard, J.G.6


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