Benzo(a)pyrene increases phosphorylation of p53 at serine 392 in relation to p53 induction and cell death in MCF-7 cells

Toxicology Letters

Volumn 178, Issue 3, 2008, Pages 152-159

  Tampio, M ^a   Loikkanen, J ^a   Myllynen, P ^b   Mertanen, A ^a   Vahakangas K H ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

Benzo(a)pyrene; BPDE DNA adducts; Caspase 7; Cell viability; p53 phosphorylation

Indexed keywords

BENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; CASPASE 3; CASPASE 7; PROTEIN P53; PROTEINASE; SERINE;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CARCINOMA CELL; CELL DEATH; CELL TYPE; CONTROLLED STUDY; DNA ADDUCT; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION;

ADENOCARCINOMA; APOPTOSIS; BENZO(A)PYRENE; BREAST NEOPLASMS; CARCINOGENS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA ADDUCTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; PHOSPHORYLATION; SERINE; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE; RATTUS;

EID: 43049170219     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.03.006     Document Type: Article

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