Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1α expression in tumor cells and hepatocytes

Gene Therapy

Volumn 15, Issue 8, 2008, Pages 572-582

  Takahashi, Y ^a   Nishikawa, M ^a   Takakura, Y ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLASMID DNA; SHORT HAIRPIN RNA; GELATINASE A; GELATINASE B; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GENE THERAPY; CANCER GROWTH; CANCER INHIBITION; CELL COUNT; CONTROLLED STUDY; DRUG EFFICACY; GENE TARGETING; HYDRODYNAMICS; IN VITRO STUDY; LIVER CANCER; LIVER CELL; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; LIVER; LIVER TUMOR; METABOLISM; METASTASIS; METHODOLOGY; PATHOLOGY; PLASMID; TUMOR CELL LINE; WESTERN BLOTTING;

MUS;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE THERAPY; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER; LIVER NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PLASMIDS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 43049158067     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3303103     Document Type: Article

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