Profiling genomic copy number changes in retinoblastoma beyond loss of RB1

Genes Chromosomes and Cancer

Volumn 46, Issue 2, 2007, Pages 118-129

  Bowles, Ella ^a,b,c   Corson, Timothy W ^a,c   Bayani, Jane ^a   Squire, Jeremy A ^a,c   Wong, Nathalie ^d   Lai, Paul B S ^d   Gallie, Brenda L ^a,c  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR E2F3;

ALLELE; ARTICLE; BONE MARROW METASTASIS; BREAST CANCER; CANCER RESEARCH; CDH11 GENE; CELL LINE; CHROMOSOME 1; CHROMOSOME 16; CHROMOSOME 16Q; CHROMOSOME 1Q; CHROMOSOME 6; CHROMOSOME 6P; CLINICAL ARTICLE; CONTROLLED STUDY; DEK GENE; DISEASE ASSOCIATION; DNA DETERMINATION; E2F3 GENE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOSS; GENE NUMBER; HUMAN; HUMAN CELL; HUMAN TISSUE; KIF14 GENE; LIVER CELL CARCINOMA; MARKER GENE; MULTIPLEX POLYMERASE CHAIN REACTION; MYCN GENE; NGFR GENE; ONCOGENE; ONCOGENE RB1; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINOBLASTOMA; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TREATMENT RESPONSE; TUMOR; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; CELL LINE, TUMOR; GENE DOSAGE; GENES, RETINOBLASTOMA; HUMANS; POLYMERASE CHAIN REACTION; RETINAL NEOPLASMS; RETINOBLASTOMA; RETINOBLASTOMA PROTEIN; SEQUENCE DELETION;

EID: 33845505450     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20383     Document Type: Article

References (49)

1. Aragona M, Panetta S, Silipigni AM, Romeo DL, Pastura G, Mesiti M, Cascinu S, La Torre F. 2001. Nerve growth factor receptor immunoreactivity in breast cancer patients. Cancer Invest 19:692-697.
2. Bailey JA, Yavor AM, Massa HF, Trask BJ, Eichler EE. 2001. Segmental duplications: Organization and impact within the current human genome project assembly. Genome Res 11:1005-1017.
3. Baudis M, Cleary ML. 2001. Progenetix.net: An online repository for molecular cytogenetic aberration data. Bioinformatics 17:1228-1229.
4. Bayani J, Squire J. 2004. Fluorescence in situ hybridization. In: Bonifacino JS, Dasso M, Lippincott-Schwartz J, Yamada KM, editors. Current Protocols in Cell Biology. Hoboken, NJ: Wiley, Unit 22.4.
5. Chan HS, Gallie BL, DeBoer G, Haddad G, Ikegaki N, Dimitroulakos J, Yeger H, Ling V. 1997. MYCN protein expression as a predictor of neuroblastoma prognosis. Clin Cancer Res 3:1699-1706.
6. Chen D, Gallie BL, Squire JA. 2001. Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization. Cancer Genet Cytogenet 129:57-63.
7. Chen D, Pajovic S, Duckett A, Brown VD, Squire JA, Gallie BL. 2002. Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN. Cancer Res 62:967-971.
8. Choi SW, Lee TW, Yang SW, Hong WS, Kim CM, Lee JO. 1993. Loss of retinoblastoma gene and amplification of N-myc gene in retinoblastoma. J Korean Med Sci 8:73-77.
9. Choy KW, Lee TC, Cheung KF, Fan DS, Lo KW, Beaverson KL, Abramson DH, Lam DS, Yu CB, Pang CP. 2005. Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. Neoplasia 7:200-206.
10. Choy KW, Pang CP, Fan DS, Lee TC, Wang JH, Abramson DH, Lo KW, To KF, Yu CB, Beaverson KL, Cheung KF, Lam DS. 2004. Microsatellite instability and MLH1 promoter methylation in human retinoblastoma. Invest Ophthalmol Vis Sci 45:3404-3409.
11. 6-methylguanine-DNA methyltransferase in retinoblastoma tissues. Invest Ophthalmol Vis Sci 43:1344-1349.
12. Corson TW, Gallie BL. 2006. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int J Cancer 119:1088-1094.
13. Corson TW, Huang A, Tsao MS, Gallie BL. 2005. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene 24:4741-4753.
14. Davidson B, Reich R, Lazarovici P, Ann Florenes V, Nielsen S, Nesland JM. 2004. Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma. Breast Cancer Res Treat 83:119-128.
15. Dimaras H, Coburn B, Pajovic S, Gallie BL. 2006. Loss of p75 neurotrophin receptor expression accompanies malignant progression to human and murine retinoblastoma. Mol Carcinogen 45:333-343.
16. Doz F, Peter M, Schleiermacher G, Vielh P, Validire P, Putterman M, Blanquet V, Desjardins L, Dufier JL, Zucker JM, Mosseri V, Thomas G, Magdelenat H, Delattre O. 1996. N-MYC amplification, loss of heterozygosity on the short arm of chromosome 1 and DNA ploidy in retinoblastoma. Eur J Cancer 32A:645-649.
17. Feltes CM, Kudo A, Blaschuk O, Byers SW. 2002. An alternatively spliced cadherin-11 enhances human breast cancer cell invasion. Cancer Res 62:6688-6697.
18. Gallie BL, Campbell C, Devlin H, Duckett A, Squire JA. 1999a. Developmental basis of retinal-specific induction of cancer by RB mutation. Cancer Res 59:1731s-1735s.
19. Gallie BL, Ellsworth RM, Abramson DH, Phillips RA. 1982. Retinoma: Spontaneous regression of retinoblastoma or benign manifestation of the mutation? Br J Cancer 45:513-521.
20. Gallie BL, Trogadis J, Han L-P. 1999b. Retinoblastoma. In: Masters JR, Palsson B, editors. Human Cell Culture. Dordrecht: Springer, pp. 361-374.
21. George RE, London WB, Cohn SL, Maris JM, Kretschmar C, Diller L, Brodeur GM, Castleberry RP, Look AT. 2005. Hyperdiploidy plus nonamplified MYCN confers a favorable prognosis in children 12 to 18 months old with disseminated neuroblastoma: A pediatric oncology group study. J Clin Oncol 23:6466-6473.
22. Godbout R, Packer M, Bie W. 1998. Overexpression of a DEAD box protein (DDX1) in neuroblastoma and retinoblastoma cell lines. J Biol Chem 273:21161-21168.
23. Grasemann C, Gratias S, Stephan H, Schuler A, Schramm A, Klein-Hitpass L, Rieder H, Schneider S, Kappes F, Eggert A, Lohmann DR. 2005. Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. Oncogene 24:6441-6449.
24. Gratias S, Schuler A, Hitpass LK, Stephan H, Rieder H, Schneider S, Horsthemke B, Lohmann DR. 2005. Genomic gains on chromosome 1q in retinoblastoma: Consequences on gene expression and association with clinical manifestation. Int J Cancer 116:555-563.
25. Herzog S, Lohmann DR, Buiting K, Schuler A, Horsthemke B, Rehder H, Rieder H. 2001. Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization. Hum Genet 108:98-104.
26. Knudson AG, Jr. 1971. Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823.
27. Kondoh N, Wakatsuki T, Ryo A, Hada A, Aihara T, Horiuchi S, Goseki N, Matsubara O, Takenaka K, Shichita M, Tanaka K, Shuda M, Yamamoto M. 1999. Identification and characterization of genes associated with human hepatocellular carcinogenesis. Cancer Res 59:4990-4996.
28. Lee WH, Murphree AL, Benedict WF. 1984. Expression and amplification of the N-myc gene in primary retinoblastoma. Nature 309:458-460.
29. Lillington DM, Goff LK, Kingston JE, Onadim Z, Price E, Domizio P, Young BD. 2002. High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours. Br J Cancer 87:779-782.
30. Lillington DM, Kingston JE, Coen PG, Price E, Hungerford J, Domizio P, Young BD, Onadim Z. 2003. Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome. Genes Chromosomes Cancer 36:121-128.
31. Lu ZL, Luo DZ, Wen JM. 2005. Expression and significance of tumor-related genes in HCC. World J Gastroenterol 11:3850-3854.
32. Mairal A, Pinglier E, Gilbert E, Peter M, Validire P, Desjardins L, Doz F, Aurias A, Couturier J. 2000. Detection of chromosome imbalances in retinoblastoma by parallel karyotype and CGH analyses. Genes Chromosomes Cancer 28:370-379.
33. Marchong MN, Chen D, Corson TW, Lee C, Harmandayan M, Bowles E, Chen N, Gallie BL. 2004. Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma. Mol Cancer Res 2:495-503.
34. Oliveros O, Yunis E. 1995. Chromosome evolution in retinoblastoma. Cancer Genet Cytogenet 82:155-160.
35. Orlic M, Spencer CE, Wang L, Gallie BL. 2006. Expression analysis of 6p22 genomic gain in retinoblastoma. Genes Chromosomes Cancer 45:72-82.
36. Pishvaian MJ, Feltes CM, Thompson P, Bussemakers MJ, Schalken JA, Byers SW. 1999. Cadherin-11 is expressed in invasive breast cancer cell lines. Cancer Res 59:947-952.
37. Popnikolov NK, Cavone SM, Schultz PM, Garcia FU. 2005. Diagnostic utility of p75 neurotrophin receptor (p75NTR) as a marker of breast myoepithelial cells. Mod Pathol 18:1535-1541.
38. Potluri VR, Helson L, Ellsworth RM, Reid T, Gilbert F. 1986. Chromosomal abnormalities in human retinoblastoma. A review. Cancer 58:663-671.
39. Reis-Filho JS, Steele D, Di Palma S, Jones RL, Savage K, James M, Milanezi F, Schmitt FC, Ashworth A. 2006. Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue. Mod Pathol 19:307-319.
40. Richter S, Vandezande K, Chen N, Zhang K, Sutherland J, Anderson J, Han L, Panton R, Branco P, Gallie B. 2003. Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma. Am J Hum Genet 72:253-269.
41. Sakai K, Tanooka H, Sasaki MS, Ejima Y, Kaneko A. 1988. Increase in copy number of N-myc in retinoblastomas in comparison with chromosome abnormality. Cancer Genet Cytogenet 30:119-126.
42. Sakamoto Y, Kitajima Y, Edakuni G, Hamamoto T, Miyazaki K. 2001. Combined evaluation of NGF and p75NGFR expression is a biomarker for predicting prognosis in human invasive ductal breast carcinoma. Oncol Rep 8:973-980.
43. Schwab M. 2004. MYCN in neuronal tumours. Cancer Lett 204:179-187.
44. Squire J, Gallie BL, Phillips RA. 1985. A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma. Hum Genet 70:291-301.
45. Squire J, Goddard AD, Canton M, Becker A, Phillips RA, Gallie BL. 1986. Tumour induction by the retinoblastoma mutation is independent of N-myc expression. Nature 322:555-557.
46. Stoecklein NH, Erbersdobler A, Schmidt-Kittler O, Diebold J, Schardt JA, Izbicki JR, Klein CA. 2002. SCOMP is superior to degenerated oligonucleotide primed-polymerase chain reaction for global amplification of minute amounts of DNA from microdissected archival tissue samples. Am J Pathol 161:43-51.
47. van der Wal JE, Hermsen MA, Gille HJ, Schouten-Van Meeteren NY, Moll AC, Imhof SM, Meijer GA, Baak JP, van der Valk P. 2003. Comparative genomic hybridisation divides retinoblastomas into a high and a low level chromosomal instability group. J Clin Pathol 56:26-30.
48. Williamson D, Lu YJ, Gordon T, Sciot R, Kelsey A, Fisher C, Poremba C, Anderson J, Pritchard-Jones K, Shipley J. 2005. Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. J Clin Oncol 23:880-888.
49. Zielinski B, Gratias S, Toedt G, Mendrzyk F, Stange DE, Radlwimmer B, Lohmann DR, Lichter P. 2005. Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization. Genes Chromosomes Cancer 43:294-301.