-
1
-
-
9344240407
-
Use of predicted mortality to evaluate the efficacy of anti-cytokine therapy in sepsis: The IL-1ra Phase III Sepsis Syndrome Study Group
-
Knaus WA, Harrell FE, LaBrecque JF, Wagner DP, Pribble JP, Draper EA, Fisher CJ, Soll L (1996) Use of predicted mortality to evaluate the efficacy of anti-cytokine therapy in sepsis: the IL-1ra Phase III Sepsis Syndrome Study Group. Crit Care Med 24:46-56
-
(1996)
Crit Care Med
, vol.24
, pp. 46-56
-
-
Knaus, W.A.1
Harrell, F.E.2
Labrecque, J.F.3
Wagner, D.P.4
Pribble, J.P.5
Draper, E.A.6
Fisher, C.J.7
Soll, L.8
-
2
-
-
8544262221
-
Efficacy and safety of the monoclonal anti-tumor necrosis factor F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
-
Monoclonal Anti-TNF: a Randomized Controlled Sepsis Study Investigators
-
Panacek EA, Marshall JC, Albertson TE, Johnson DH, Johnson S, MacArthur RD, Miller M, Barchuk WT, Fischkoff S, Kaul M, Teoh L, Van Meter L, Daum L, Lemeshow S, Hicklin G, Doig C, Monoclonal Anti-TNF: a Randomized Controlled Sepsis Study Investigators (2004) Efficacy and safety of the monoclonal anti-tumor necrosis factor F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med 32:2173-2182
-
(2004)
Crit Care Med
, vol.32
, pp. 2173-2182
-
-
Panacek, E.A.1
Marshall, J.C.2
Albertson, T.E.3
Johnson, D.H.4
Johnson, S.5
MacArthur, R.D.6
Miller, M.7
Barchuk, W.T.8
Fischkoff, S.9
Kaul, M.10
Teoh, L.11
Van Meter, L.12
Daum, L.13
Lemeshow, S.14
Hicklin, G.15
Doig, C.16
-
3
-
-
0036840629
-
Risk and efficacy of anti-inflammatory agents: Retrospective and confirmatory studies of sepsis
-
Eichacker PQ, Parent C, Kalil A, Esposito C, Cui X, Banks SM, Gerstenberger EP, Fitz Y, Danner RL, Natanson C (2002) Risk and efficacy of anti-inflammatory agents: retrospective and confirmatory studies of sepsis. Am J Respir Crit Care Med 166:1197-1205
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1197-1205
-
-
Eichacker, P.Q.1
Parent, C.2
Kalil, A.3
Esposito, C.4
Cui, X.5
Banks, S.M.6
Gerstenberger, E.P.7
Fitz, Y.8
Danner, R.L.9
Natanson, C.10
-
4
-
-
4644288960
-
Severity of sepsis alters the effects of superoxide anion inhibition in a rat sepsis model
-
Cui X, Parent C, Macarthur H, Ochs SD, Gerstenberg E, Solomon S, Fitz Y, Danner RL, Banks SM, Natanson C, Salvemini D, Eichacker PQ (2004) Severity of sepsis alters the effects of superoxide anion inhibition in a rat sepsis model. J Appl Physiol 97:1349-1357
-
(2004)
J Appl Physiol
, vol.97
, pp. 1349-1357
-
-
Cui, X.1
Parent, C.2
MacArthur, H.3
Ochs, S.D.4
Gerstenberg, E.5
Solomon, S.6
Fitz, Y.7
Danner, R.L.8
Banks, S.M.9
Natanson, C.10
Salvemini, D.11
Eichacker, P.Q.12
-
5
-
-
0035826096
-
Efficacy and safety of recombinant activated protein C for severe sepsis
-
Recombinant Human Protein Worldwide Evaluation in Severe Sepsis (PROWESS) Study Group
-
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr; Recombinant Human Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) Study Group (2001) Efficacy and safety of recombinant activated protein C for severe sepsis. N Engl J Med 344:699-709
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
Larosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Jr. Fisher, C.J.C.11
-
6
-
-
3042858950
-
Meta-analysis: The effect of steroids on survival and shock during sepsis depended on dose
-
Minneci PC, Deans KJ, Banks SM, Eichacker PQ, Natanson C (2004) Meta-analysis: the effect of steroids on survival and shock during sepsis depended on dose. Ann Intern Med 141:47-56
-
(2004)
Ann Intern Med
, vol.141
, pp. 47-56
-
-
Minneci, P.C.1
Deans, K.J.2
Banks, S.M.3
Eichacker, P.Q.4
Natanson, C.5
-
7
-
-
0031942028
-
Reversal of late septic shock with supraphysiologic dose hydrocortisone
-
Bollaert PE, Charpentier C, Levy B, Debouverie M, Audibert G, Larcan A (1998) Reversal of late septic shock with supraphysiologic dose hydrocortisone. Crit Care Med 26:645-650
-
(1998)
Crit Care Med
, vol.26
, pp. 645-650
-
-
Bollaert, P.E.1
Charpentier, C.2
Levy, B.3
Debouverie, M.4
Audibert, G.5
Larcan, A.6
-
8
-
-
0035998343
-
Physiological-dose steroid therapy in sepsis [ISRCTN36253388]
-
Yildiz O, Doganay M, Aygen B, Guven M, Keletimur F, Tutus A (2002) Physiological-dose steroid therapy in sepsis [ISRCTN36253388]. Crit Care 6:251-259
-
(2002)
Crit Care
, vol.6
, pp. 251-259
-
-
Yildiz, O.1
Doganay, M.2
Aygen, B.3
Guven, M.4
Keletimur, F.5
Tutus, A.6
-
9
-
-
0037151571
-
Effect of treatment with low doses of corticosteroid and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, Capellier G, Cohen Y, Azoulay E, Troche G, Chaumet-Riffaut P, Bellissant E (2002) Effect of treatment with low doses of corticosteroid and fludrocortisone on mortality in patients with septic shock. JAMA 288:862-871
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
Bollaert, P.E.4
Francois, B.5
Korach, J.M.6
Capellier, G.7
Cohen, Y.8
Azoulay, E.9
Troche, G.10
Chaumet-Riffaut, P.11
Bellissant, E.12
-
10
-
-
19944430688
-
Hydrocortisone infusion for severe community-acquired pneumonia. a preliminary randomized study
-
Confalonieri M, Urbino R, Potena A, Piattella M, Parigi P, Puccio G, Della Porta R, Giorgio C, Blasi F, Umberger R, Meduri GU (2005) Hydrocortisone infusion for severe community-acquired pneumonia. A preliminary randomized study. Am J Respir Crit Care Med 171:242-248
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 242-248
-
-
Confalonieri, M.1
Urbino, R.2
Potena, A.3
Piattella, M.4
Parigi, P.5
Puccio, G.6
Della Porta, R.7
Giorgio, C.8
Blasi, F.9
Umberger, R.10
Meduri, G.U.11
-
11
-
-
34347325784
-
Corticosteroid therapy of septic shock (CORTICUS)
-
Sprung CL, Annane D, Briegel J, Keh D, Moreno R, Singer M, Weiss Y, Sorenson F (2007) Corticosteroid therapy of septic shock (CORTICUS). Am J Respir Crit Care Med 175:A507
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 507
-
-
Sprung, C.L.1
Annane, D.2
Briegel, J.3
Keh, D.4
Moreno, R.5
Singer, M.6
Weiss, Y.7
Sorenson, F.8
-
12
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303-1310
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
13
-
-
0032421414
-
Community-acquired pneumonia due to Escherichia coli
-
Marrie TJ, Fine MJ, Obrosky DS, Coley C, Singer DE, Kapoor WN (1998) Community-acquired pneumonia due to Escherichia coli. Clin Microbiol Infect 4:717-723
-
(1998)
Clin Microbiol Infect
, vol.4
, pp. 717-723
-
-
Marrie, T.J.1
Fine, M.J.2
Obrosky, D.S.3
Coley, C.4
Singer, D.E.5
Kapoor, W.N.6
-
14
-
-
0345601956
-
Ventilator-associated pneumonia in a multi-hospital system: Differences in microbiology by location
-
Babcock HM, Zack JE, Garrison T, Trovillion E, Kollef MH, Fraser VJ (2003) Ventilator-associated pneumonia in a multi-hospital system: differences in microbiology by location. Infect Control Hosp Epidemiol 24:853-858
-
(2003)
Infect Control Hosp Epidemiol
, vol.24
, pp. 853-858
-
-
Babcock, H.M.1
Zack, J.E.2
Garrison, T.3
Trovillion, E.4
Kollef, M.H.5
Fraser, V.J.6
-
15
-
-
43049094205
-
-
http://www.globalrph.com/corticocalc.htm
-
-
-
-
16
-
-
0018363899
-
Experimental gram-negative bacterial sepsis: Prevention of mortality not preventable by antibiotics alone
-
Greisman SE, DuBuy JB, Woodward CL (1979) Experimental gram-negative bacterial sepsis: prevention of mortality not preventable by antibiotics alone. Infect Immun 25:538-557
-
(1979)
Infect Immun
, vol.25
, pp. 538-557
-
-
Greisman, S.E.1
Dubuy, J.B.2
Woodward, C.L.3
-
17
-
-
0021665703
-
Endotoxemia induced by antibiotic therapy: A mechanism for adrenal corticosteroid protection in gram-negative sepsis
-
Johnston CA, Greisman SE (1984) Endotoxemia induced by antibiotic therapy: a mechanism for adrenal corticosteroid protection in gram-negative sepsis. Trans Assoc Am Physicians 97:172-181
-
(1984)
Trans Assoc Am Physicians
, vol.97
, pp. 172-181
-
-
Johnston, C.A.1
Greisman, S.E.2
-
18
-
-
0020396656
-
Experimental Gram-negative bacterial sepsis: Optimal methylprednisolone requirements for prevention of mortality not preventable by antibiotics alone
-
Greisman SE (1982) Experimental Gram-negative bacterial sepsis: optimal methylprednisolone requirements for prevention of mortality not preventable by antibiotics alone. Proc Soc Exp Biol Med 170:436-442
-
(1982)
Proc Soc Exp Biol Med
, vol.170
, pp. 436-442
-
-
Greisman, S.E.1
-
19
-
-
8944251133
-
Controlled trials of rG-CSF and CD11b-directed MAb during hyperoxia and E. coli pneumonia in rats
-
Freeman BD, Correa R, Karzai W, Natanson C, Patterson M, Banks S, Fitz Y, Danner RL, Wilson L, Eichacker PQ (1996) Controlled trials of rG-CSF and CD11b-directed MAb during hyperoxia and E. coli pneumonia in rats. J Appl Physiol 80:2066-2076
-
(1996)
J Appl Physiol
, vol.80
, pp. 2066-2076
-
-
Freeman, B.D.1
Correa, R.2
Karzai, W.3
Natanson, C.4
Patterson, M.5
Banks, S.6
Fitz, Y.7
Danner, R.L.8
Wilson, L.9
Eichacker, P.Q.10
-
20
-
-
12144288811
-
Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats
-
Cui X, Moayeri M, Li Y, Li X, Haley M, Fitz Y, Correa-Araujo R, Banks SM, Leppla SH, Eichacker PQ (2004) Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats. Am J Physiol Regul Integr Comp Physiol 286:R699-R709
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.286
-
-
Cui, X.1
Moayeri, M.2
Li, Y.3
Li, X.4
Haley, M.5
Fitz, Y.6
Correa-Araujo, R.7
Banks, S.M.8
Leppla, S.H.9
Eichacker, P.Q.10
-
21
-
-
33747186373
-
DTPA Fe(III) decreases cytokines and hypotension but worsens survival with Escherichia coli sepsis in rats
-
Li Y, Li X, Haley M, Fitz Y, Gerstenberger E, Banks SM, Eichacker PQ, Cui X (2006) DTPA Fe(III) decreases cytokines and hypotension but worsens survival with Escherichia coli sepsis in rats. Intensive Care Med 32:1263-1270
-
(2006)
Intensive Care Med
, vol.32
, pp. 1263-1270
-
-
Li, Y.1
Li, X.2
Haley, M.3
Fitz, Y.4
Gerstenberger, E.5
Banks, S.M.6
Eichacker, P.Q.7
Cui, X.8
-
22
-
-
33846811743
-
Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model
-
Cui X, Li Y, Li X, Laird MW, Subramanian M, Moayeri M, Leppla SH, Fitz Y, Su J, Sherer K, Eichacker PQ (2007) Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model. J Infect Dis 195:572-580
-
(2007)
J Infect Dis
, vol.195
, pp. 572-580
-
-
Cui, X.1
Li, Y.2
Li, X.3
Laird, M.W.4
Subramanian, M.5
Moayeri, M.6
Leppla, S.H.7
Fitz, Y.8
Su, J.9
Sherer, K.10
Eichacker, P.Q.11
-
23
-
-
0002106251
-
Hydrocortisone reverses refractory septic shock [abstract]
-
1
-
Chawla K, Kupfer Y, Goldman I (1999) Hydrocortisone reverses refractory septic shock [abstract]. Crit Care Med [Suppl] 27(1):A33
-
(1999)
Crit Care Med [Suppl]
, vol.27
, pp. 33
-
-
Chawla, K.1
Kupfer, Y.2
Goldman, I.3
-
24
-
-
27944471374
-
Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock
-
Oppert M, Schindler R, Husung C, Offermann K, Graf KJ, Boenisch O, Barckow D, Frei U, Eckardt KU (2005) Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med 33:2457-2464
-
(2005)
Crit Care Med
, vol.33
, pp. 2457-2464
-
-
Oppert, M.1
Schindler, R.2
Husung, C.3
Offermann, K.4
Graf, K.J.5
Boenisch, O.6
Barckow, D.7
Frei, U.8
Eckardt, K.U.9
-
25
-
-
0035144237
-
Immunomodulation in septic shock: Hydrocortisone differentially regulates cytokine responses
-
Briegel J, Jochum M, Gippner-Steppert C, Thiel M (2001) Immunomodulation in septic shock: hydrocortisone differentially regulates cytokine responses. J Am Soc Nephrol 12:S70-S74
-
(2001)
J Am Soc Nephrol
, vol.12
-
-
Briegel, J.1
Jochum, M.2
Gippner-Steppert, C.3
Thiel, M.4
-
26
-
-
0037441670
-
Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock. a double-blind, randomized, placebo-controlled, crossover study
-
Keh D, Boehnke T, Weber-Cartens S, Schulz C, Ahlers O, Bercker S, Volk HD, Doecke WD, Falke KJ, Gerlach H (2003) Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock. A double-blind, randomized, placebo-controlled, crossover study. Am J Respir Crit Care Med 167:512-520
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 512-520
-
-
Keh, D.1
Boehnke, T.2
Weber-Cartens, S.3
Schulz, C.4
Ahlers, O.5
Bercker, S.6
Volk, H.D.7
Doecke, W.D.8
Falke, K.J.9
Gerlach, H.10
-
27
-
-
0032946372
-
Stress doses of hydrocortisone reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study
-
Briegel J, Forst H, Haller M, Schelling G, Kliger E, Kuprat G, Hemmer B, Hummel T, Lenhart A, Heyduck M, Stoll C, Peter K (1999) Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 27:723-731
-
(1999)
Crit Care Med
, vol.27
, pp. 723-731
-
-
Briegel, J.1
Forst, H.2
Haller, M.3
Schelling, G.4
Kliger, E.5
Kuprat, G.6
Hemmer, B.7
Hummel, T.8
Lenhart, A.9
Heyduck, M.10
Stoll, C.11
Peter, K.12
-
28
-
-
3242775982
-
Surviving sepsis campaign guidelines for management of severe sepsis and septic shock
-
Surviving Sepsis Campaign Management Guidelines Committee
-
Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM, Surviving Sepsis Campaign Management Guidelines Committee (2004) Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 32:858-873
-
(2004)
Crit Care Med
, vol.32
, pp. 858-873
-
-
Dellinger, R.P.1
Carlet, J.M.2
Masur, H.3
Gerlach, H.4
Calandra, T.5
Cohen, J.6
Gea-Banacloche, J.7
Keh, D.8
Marshall, J.C.9
Parker, M.M.10
Ramsay, G.11
Zimmerman, J.L.12
Vincent, J.L.13
Levy, M.M.14
-
29
-
-
0038819899
-
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock
-
Mansart A, Bollaert PE, Seguin C, Levy B, Longrois D, Mallie JP (2003) Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. Shock 19:38-44
-
(2003)
Shock
, vol.19
, pp. 38-44
-
-
Mansart, A.1
Bollaert, P.E.2
Seguin, C.3
Levy, B.4
Longrois, D.5
Mallie, J.P.6
-
30
-
-
0031722907
-
Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve
-
Annane D, Bellissant E, Sebille V, Lesieur O, Mathieu B, Raphael JC, Gajdos P (1998) Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve. Br J Clin Pharmacol 46:589-597
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 589-597
-
-
Annane, D.1
Bellissant, E.2
Sebille, V.3
Lesieur, O.4
Mathieu, B.5
Raphael, J.C.6
Gajdos, P.7
-
31
-
-
4344618571
-
Corticosteroids for severe sepsis and septic shock: A systematic review and meta-analysis
-
Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y (2004) Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ 329:480
-
(2004)
BMJ
, vol.329
, pp. 480
-
-
Annane, D.1
Bellissant, E.2
Bollaert, P.E.3
Briegel, J.4
Keh, D.5
Kupfer, Y.6
-
32
-
-
0023605292
-
The phenomenon and cause of the dose-dependent oral absorption of chlorothiazide in rats: Extrapolation to human data based on the body surface area concept
-
Hsu FH, Prueksaritanont T, Lee MG, Chiou WL (1987) The phenomenon and cause of the dose-dependent oral absorption of chlorothiazide in rats: extrapolation to human data based on the body surface area concept. J Pharmacokinet Biopharm 15:369-386
-
(1987)
J Pharmacokinet Biopharm
, vol.15
, pp. 369-386
-
-
Hsu, F.H.1
Prueksaritanont, T.2
Lee, M.G.3
Chiou, W.L.4
-
33
-
-
23944457633
-
Stability of dexamethasone sodium phosphate in rat plasma
-
Samtani MN, Jusko WJ (2005) Stability of dexamethasone sodium phosphate in rat plasma. Int J Pharm 301:262-266
-
(2005)
Int J Pharm
, vol.301
, pp. 262-266
-
-
Samtani, M.N.1
Jusko, W.J.2
-
34
-
-
0018630001
-
Differential potencies of corticosterone and hydrocortisone in immune and immune-related processes in the mouse
-
Van Dijk H, Bloksma N, Rademaker PM, Schouten WJ, Willers JM (1979) Differential potencies of corticosterone and hydrocortisone in immune and immune-related processes in the mouse. Int J Immmunopharmacol 1:285-292
-
(1979)
Int J Immmunopharmacol
, vol.1
, pp. 285-292
-
-
Van Dijk, H.1
Bloksma, N.2
Rademaker, P.M.3
Schouten, W.J.4
Willers, J.M.5
-
35
-
-
0026463754
-
Comparison of antibacterial efficacies of ampicillin and ciprofloxacin against experimental infections with Listeria monocytogenes in hydrocortisone-treated mice
-
Van Ogtrop ML, Mattie H, Sekh BR, Van Strijen E, Van Furth R (1992) Comparison of antibacterial efficacies of ampicillin and ciprofloxacin against experimental infections with Listeria monocytogenes in hydrocortisone-treated mice. Antimicrob Agents Chemother 36:2375-2380
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 2375-2380
-
-
Van Ogtrop, M.L.1
Mattie, H.2
Sekh, B.R.3
Van Strijen, E.4
Van Furth, R.5
|