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Volumn 32, Issue 8, 2006, Pages 1263-1270

DTPA Fe(III) decreases cytokines and hypotension but worsens survival with Escherichia coli sepsis in rats

Author keywords

DTPA Fe(III); Nitric oxide inhibition; Sepsis; Septic shock; Treatment

Indexed keywords

CYTOKINE; FERRIC ION; INTERLEUKIN 1; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PENTETIC ACID DERIVATIVE; PENTETIC ACID IRON COMPLEX; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 33747186373     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-006-0234-2     Document Type: Article
Times cited : (7)

References (38)
  • 1
    • 0029864356 scopus 로고    scopus 로고
    • Nitric oxide and septic shock
    • Cobb JP, Danner RL (1996) Nitric oxide and septic shock. JAMA 275:1192-1196
    • (1996) JAMA , vol.275 , pp. 1192-1196
    • Cobb, J.P.1    Danner, R.L.2
  • 2
    • 0029803759 scopus 로고    scopus 로고
    • Role of nitric oxide in the circulatory failure and organ injury in a rodent model of gram-positive shock
    • Kengatharan KM, De Kimpe SJ, Thiemermann C (1996) Role of nitric oxide in the circulatory failure and organ injury in a rodent model of gram-positive shock. Br J Pharmacol 119:1411-1421
    • (1996) Br J Pharmacol , vol.119 , pp. 1411-1421
    • Kengatharan, K.M.1    De Kimpe, S.J.2    Thiemermann, C.3
  • 3
    • 0036740393 scopus 로고    scopus 로고
    • Different mechanism of LPS-induced vasodilation in resistance and conductance arteries from SHR and normotensive rats
    • Farias NC, Borelli-Montigny GL, Fauaz G, Feres T, Borges AC, Paiva TB (2002) Different mechanism of LPS-induced vasodilation in resistance and conductance arteries from SHR and normotensive rats. Br J Pharmacol 137:213-220
    • (2002) Br J Pharmacol , vol.137 , pp. 213-220
    • Farias, N.C.1    Borelli-Montigny, G.L.2    Fauaz, G.3    Feres, T.4    Borges, A.C.5    Paiva, T.B.6
  • 4
    • 0024993323 scopus 로고
    • Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo
    • Thiemermann C, Vane J (1990) Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo. Eur J Pharmacol 182:591-595
    • (1990) Eur J Pharmacol , vol.182 , pp. 591-595
    • Thiemermann, C.1    Vane, J.2
  • 6
    • 0030035510 scopus 로고    scopus 로고
    • Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli
    • Molina L, Studenberg S, Wolberg G, Kazmierski W, Wilson J, Tadepalli A, Chang AC, Kosanke S, Hinshaw L (1996) Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli. J Clin Invest 98:192-198
    • (1996) J Clin Invest , vol.98 , pp. 192-198
    • Molina, L.1    Studenberg, S.2    Wolberg, G.3    Kazmierski, W.4    Wilson, J.5    Tadepalli, A.6    Chang, A.C.7    Kosanke, S.8    Hinshaw, L.9
  • 7
    • 0026674684 scopus 로고
    • N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin
    • Cobb JP, Natanson C, Hoffman WD, Lodato RF, Banks S, Koev CA, Solomon MA, Elin RJ, Hosseini JM, Danner RL (1992) N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin. J Exp Med 176:1175-1182
    • (1992) J Exp Med , vol.176 , pp. 1175-1182
    • Cobb, J.P.1    Natanson, C.2    Hoffman, W.D.3    Lodato, R.F.4    Banks, S.5    Koev, C.A.6    Solomon, M.A.7    Elin, R.J.8    Hosseini, J.M.9    Danner, R.L.10
  • 10
    • 0026570471 scopus 로고
    • Roles of nitric oxide in endotoxin shock
    • Wright CE, Rees DD, Moncada S (1992) Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc Res 26:48-57
    • (1992) Cardiovasc Res , vol.26 , pp. 48-57
    • Wright, C.E.1    Rees, D.D.2    Moncada, S.3
  • 11
    • 0032133353 scopus 로고    scopus 로고
    • Design of isoform-selective inhibitors of nitric oxide synthase
    • Babu BR, Griffith OW (1998) Design of isoform-selective inhibitors of nitric oxide synthase. Curr Opin Chem Biol 2:491-500
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 491-500
    • Babu, B.R.1    Griffith, O.W.2
  • 13
    • 33747196805 scopus 로고    scopus 로고
    • Iron (III) complex of diethylenetraimine pentaacetic acid [DTPA Fe(III)] decreased nitrate/nitrite levels and increased blood pressure but not survival during E. coli sepsis in rats
    • Li Y, Molina L, Solomon S, Fitz Y, Danner RL, Natanson C, Eichacker PQ, Cui X (2004) Iron (III) complex of diethylenetraimine pentaacetic acid [DTPA Fe(III)] decreased nitrate/nitrite levels and increased blood pressure but not survival during E. coli sepsis in rats. Am J Respir Crit Care Med 169:A632
    • (2004) Am J Respir Crit Care Med , vol.169
    • Li, Y.1    Molina, L.2    Solomon, S.3    Fitz, Y.4    Danner, R.L.5    Natanson, C.6    Eichacker, P.Q.7    Cui, X.8
  • 14
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303-1310
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 16
    • 0037251861 scopus 로고    scopus 로고
    • Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples
    • Yang BK, Vivas EX, Reiter CD, Gladwin MT (2003) Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples. Free Radic Res 37:1-10
    • (2003) Free Radic Res , vol.37 , pp. 1-10
    • Yang, B.K.1    Vivas, E.X.2    Reiter, C.D.3    Gladwin, M.T.4
  • 18
    • 0024311315 scopus 로고
    • Reaction of hydroxyl radicals with the ferrous and ferric iron chelates of diethylenetriamine-N,N,N′,N″,N″-pentaacetate
    • Rahhal S, Richter HW (1989) Reaction of hydroxyl radicals with the ferrous and ferric iron chelates of diethylenetriamine-N,N,N′,N″, N″-pentaacetate. Free Radic Res Commun 6:369-377
    • (1989) Free Radic Res Commun , vol.6 , pp. 369-377
    • Rahhal, S.1    Richter, H.W.2
  • 19
    • 0000765496 scopus 로고
    • Superoxide dismutase activities of an iron porphyrin and other iron complexes
    • Pasternack R, Halliwell B (1979) Superoxide dismutase activities of an iron porphyrin and other iron complexes. J Am Chem Soc 101:1026-1031
    • (1979) J Am Chem Soc , vol.101 , pp. 1026-1031
    • Pasternack, R.1    Halliwell, B.2
  • 21
    • 0034662864 scopus 로고    scopus 로고
    • Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock
    • U S A
    • Macarthur H, Westfall TC, Riley DP, Misko TP, Salvemini D (2000) Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock. Proc Natl Acad Sci U S A 97:9753-9758
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 9753-9758
    • Macarthur, H.1    Westfall, T.C.2    Riley, D.P.3    Misko, T.P.4    Salvemini, D.5
  • 22
    • 0037251563 scopus 로고    scopus 로고
    • Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: Correlation with preserved circulating catecholamines
    • Macarthur H, Couri DM, Wilken GH, Westfall TC, Lechner AJ, Matuschak GM, Chen Z, Salvemini D (2003) Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines. Crit Care Med 31:237-245
    • (2003) Crit Care Med , vol.31 , pp. 237-245
    • Macarthur, H.1    Couri, D.M.2    Wilken, G.H.3    Westfall, T.C.4    Lechner, A.J.5    Matuschak, G.M.6    Chen, Z.7    Salvemini, D.8
  • 23
    • 0031452476 scopus 로고    scopus 로고
    • Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock
    • Dinarello CA (1997) Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock. Chest 112:321S-329S
    • (1997) Chest , vol.112
    • Dinarello, C.A.1
  • 24
    • 17544404224 scopus 로고    scopus 로고
    • Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity
    • Bogdan C, Rollinghoff M, Diefenbach A (2000) Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr Opin Immunol 12:64-76
    • (2000) Curr Opin Immunol , vol.12 , pp. 64-76
    • Bogdan, C.1    Rollinghoff, M.2    Diefenbach, A.3
  • 25
    • 0034679577 scopus 로고    scopus 로고
    • Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro
    • Vazquez-Torres A, Jones-Carson J, Mastroeni P, Ischiropoulos H, Fang FC (2000) Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. J Exp Med 192:227-236
    • (2000) J Exp Med , vol.192 , pp. 227-236
    • Vazquez-Torres, A.1    Jones-Carson, J.2    Mastroeni, P.3    Ischiropoulos, H.4    Fang, F.C.5
  • 26
    • 0034679577 scopus 로고    scopus 로고
    • Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo
    • Mastroeni P, Vazquez-Torres A, Fang FC, Xu Y, Khan S, Hormaeche CE, Dougan G (2000) Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo. J Exp Med 192:227-236
    • (2000) J Exp Med , vol.192 , pp. 227-236
    • Mastroeni, P.1    Vazquez-Torres, A.2    Fang, F.C.3    Xu, Y.4    Khan, S.5    Hormaeche, C.E.6    Dougan, G.7
  • 27
    • 0034115696 scopus 로고    scopus 로고
    • Cooperation between reactive oxygen and nitrogen intermediates in killing of Rhodococcus equi by activated macrophages
    • Darrah PA, Hondalus MK, Chen Q, Ischiropoulos H, Mosser DM (2000) Cooperation between reactive oxygen and nitrogen intermediates in killing of Rhodococcus equi by activated macrophages. Infect Immun 68:3587-3593
    • (2000) Infect Immun , vol.68 , pp. 3587-3593
    • Darrah, P.A.1    Hondalus, M.K.2    Chen, Q.3    Ischiropoulos, H.4    Mosser, D.M.5
  • 28
    • 0030846036 scopus 로고    scopus 로고
    • Role of reactive nitrogen and oxygen intermediates in gamma interferon-stimulated murine macrophage bactericidal activity against Burkholderia pseudomallei
    • Miyagi K, Kawakami K, Saito A (1997) Role of reactive nitrogen and oxygen intermediates in gamma interferon-stimulated murine macrophage bactericidal activity against Burkholderia pseudomallei. Infect Immun 65:4108-4113
    • (1997) Infect Immun , vol.65 , pp. 4108-4113
    • Miyagi, K.1    Kawakami, K.2    Saito, A.3
  • 29
    • 0029093978 scopus 로고
    • Effect of anti-tumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections
    • Mastroeni P, Skepper JN, Hormaeche CE (1995) Effect of anti-tumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections. Infect Immun 63:3674-3682
    • (1995) Infect Immun , vol.63 , pp. 3674-3682
    • Mastroeni, P.1    Skepper, J.N.2    Hormaeche, C.E.3
  • 30
    • 0026079224 scopus 로고
    • Divergent efficacy of antibody to TNF in intravascular and peritonitis models of sepsis
    • Bagby GJ, Plessala KJ, Wilson LA, Thompson JJ, Nelson S (1991) Divergent efficacy of antibody to TNF in intravascular and peritonitis models of sepsis. J Infect Dis 163:83-88
    • (1991) J Infect Dis , vol.163 , pp. 83-88
    • Bagby, G.J.1    Plessala, K.J.2    Wilson, L.A.3    Thompson, J.J.4    Nelson, S.5
  • 31
    • 0025258906 scopus 로고
    • Requirement of endogenous tumor necrosis factor/cachetin for recovery from experimental peritonitis
    • Echtenacher B, Falk W, Mannel DN, Krammer PH (1990) Requirement of endogenous tumor necrosis factor/cachetin for recovery from experimental peritonitis. J Immunol 145:3762-3766
    • (1990) J Immunol , vol.145 , pp. 3762-3766
    • Echtenacher, B.1    Falk, W.2    Mannel, D.N.3    Krammer, P.H.4
  • 32
    • 21144451354 scopus 로고    scopus 로고
    • Neutrophil inhibition with L-selectin directed mAb improves or worsens survival dependent upon the route but not severity of infection in a rat sepsis model
    • Haley M, Parent C, Cui X, Kalil A, Fitz Y, Correa-Araujo R, Natanson C, Danner RL, Banks SM, Eichacker PQ (2005) Neutrophil inhibition with L-selectin directed mAb improves or worsens survival dependent upon the route but not severity of infection in a rat sepsis model. J Appl Physiol 98:2155-2162
    • (2005) J Appl Physiol , vol.98 , pp. 2155-2162
    • Haley, M.1    Parent, C.2    Cui, X.3    Kalil, A.4    Fitz, Y.5    Correa-Araujo, R.6    Natanson, C.7    Danner, R.L.8    Banks, S.M.9    Eichacker, P.Q.10
  • 33
    • 0030035914 scopus 로고    scopus 로고
    • Counterprotective effect of erythrocytes in experimental bacterial peritonitis is due to scavenging of nitric oxide and reactive oxygen intermediates
    • Kim YM, Hong SJ, Billiar TR, Simmons RL (1996) Counterprotective effect of erythrocytes in experimental bacterial peritonitis is due to scavenging of nitric oxide and reactive oxygen intermediates. Infect Immun 64:3074-3080
    • (1996) Infect Immun , vol.64 , pp. 3074-3080
    • Kim, Y.M.1    Hong, S.J.2    Billiar, T.R.3    Simmons, R.L.4
  • 34
    • 0030915245 scopus 로고    scopus 로고
    • Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice
    • Umezawa K, Akaike T, Fujii S, Suga M, Setoguchi K, Ozawa A, Maeda H (1997) Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice. Infect Immun 65:2932-2940
    • (1997) Infect Immun , vol.65 , pp. 2932-2940
    • Umezawa, K.1    Akaike, T.2    Fujii, S.3    Suga, M.4    Setoguchi, K.5    Ozawa, A.6    Maeda, H.7
  • 35
    • 0031944732 scopus 로고    scopus 로고
    • Right ventricular overload causes the decrease in cardiac output after nitric oxide synthesis inhibition in endotoxemia
    • Cohen RI, Shapir Y, Chen L, Scharf SM (1998) Right ventricular overload causes the decrease in cardiac output after nitric oxide synthesis inhibition in endotoxemia. Crit Care Med 26:738-747
    • (1998) Crit Care Med , vol.26 , pp. 738-747
    • Cohen, R.I.1    Shapir, Y.2    Chen, L.3    Scharf, S.M.4
  • 37
    • 0032957479 scopus 로고    scopus 로고
    • Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition
    • Dahm PL, Thorne J, Myhre E, Grins E, Martensson L, Blomquist S (1999) Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition. Acta Anaesthesiol Scand 43:56-63
    • (1999) Acta Anaesthesiol Scand , vol.43 , pp. 56-63
    • Dahm, P.L.1    Thorne, J.2    Myhre, E.3    Grins, E.4    Martensson, L.5    Blomquist, S.6


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