Distinct effects of the soluble versus membrane-bound forms of the notch ligand delta-4 on human CD34+CD38low cell expansion and differentiation

Stem Cells

Volumn 26, Issue 3, 2008, Pages 621-629

  Lahmar, Medhi ^a,b,c   Catelain, Cyril ^a,b,c   Poirault, Sonia ^a,b,c   Dorsch, Marion ^d   Villeval, Jean Luc ^a,b,c   Vainchenker, William ^a,b,c   Albagli, Olivier ^a,b,c   Lauret, Evelyne ^a,b,c  

^a INSERM   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Cell proliferation; Notch; Notch signaling

Indexed keywords

BINDING PROTEIN; CD34 ANTIGEN; CD38 ANTIGEN; GAMMA SECRETASE; NOTCH RECEPTOR; SOLUBLE PROTEIN DELTA 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CSL; UNCLASSIFIED DRUG; DLL4 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL EXPANSION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; COCULTURE; CYTOLOGY; FETUS BLOOD; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLUBILITY;

ANIMALS; ANTIGENS, CD34; ANTIGENS, CD38; CELL DIFFERENTIATION; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; COCULTURE TECHNIQUES; FETAL BLOOD; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOLUBILITY;

EID: 43049128246     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0428     Document Type: Article

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