Rapid generation of a tetracycline-inducible BCR-ABL defective retrovirus using a single autoregulatory retroviral cassette

Leukemia

Volumn 15, Issue 10, 2001, Pages 1658-1662

  Dugray, A ^a   Geay, J F ^a   Foudi, A ^a   Bonnet, M L ^a   Vainchenker, W ^a   Wendling, F ^a   Louache, F ^a   Turhan, A G ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Animal models; BCR ABL; Chronic myelogenous leukemia; Inducible; Retrovirus

Indexed keywords

BCR ABL PROTEIN; COMPLEMENTARY DNA; DOXYCYCLINE; DRINKING WATER; GROWTH FACTOR; HYBRID PROTEIN; INTERLEUKIN 3; REPRESSOR PROTEIN; TETRACYCLINE;

ANIMAL CELL; ARTICLE; AUTOREGULATION; BLOOD ANALYSIS; BONE MARROW CELL; CELL IMMORTALIZATION; CELL TRANSFORMATION; CHRONIC MYELOID LEUKEMIA; CULTURE MEDIUM; CYTOMEGALOVIRUS; DISEASE MODEL; DNA VECTOR; EMBRYO; EMBRYO CELL; FEASIBILITY STUDY; GENE CASSETTE; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENE TRANSFER; GENETIC SCREENING; GENETIC STABILITY; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; INHIBITION KINETICS; IRRADIATION; KIDNEY CELL; LEUKEMIA; MOLECULAR CLONING; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFECT; PROTEIN EXPRESSION; REPRESSOR GENE; RETROVIRUS; TIME; TUMOR GROWTH; TUMOR REGRESSION; VESICULAR STOMATITIS VIRUS;

EID: 0034772693     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402225     Document Type: Article

References (19)

1. Chronic myeloid leukemia
2. New understanding of the pathogenesis of CML: A prototype of early neoplasia
3. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
4. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow
5. Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: A novel model for chronic myelogenous leukemia
6. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
7. Transcriptional activation by tetracyclines in mammalian cells
8. Tet B or not tet B: Advances in tetracycline-inducible gene expression
9. Ecdysone-inducible gene expression in mammalian cells and transgenic mice
10. A humanized system for pharmacologic control of gene expression
11. Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression
12. Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette
13. BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line
14. A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
15. Retroviral particles produced from a stable human-derived packaging cell line transduce target cells with very high efficiencies
16. Reversibility of acute B-cell leukaemia induced by BCR-ABL1
17. High efficiency in vitro gene transfer into vascular tissues using a pseudotyped retroviral vector without pseudotransduction
18. Vesicular stomatitis virus G pseudotyped retrovector mediates effective in vivo suicide gene delivery in experimental brain cancer
19. Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes