Selective gene transfer to endometrial cancer cells by a polymer against matrix metalloproteinase 2 (MMP-2)

Cancer Biotherapy and Radiopharmaceuticals

Volumn 23, Issue 2, 2008, Pages 247-258

  Han, Joo Youn ^a   Choi, Dong Soon ^a   Kim, Changhoon ^b   Joo, Hyun ^c   Min, Churl K ^a  

^a Ajou University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Inje University   (South Korea)

Author keywords

Anti MMP 2 antibody; Coculture; Endometrial cancers; Gene delivery; PEI

Indexed keywords

3 (2 PYRIDYLDITHIO)PROPIONIC ACID N HYDROXYSUCCINIMIDE ESTER; DNA; GELATINASE A; GREEN FLUORESCENT PROTEIN; POLYETHYLENEIMINE; POLYMER; PROTEIN ANTIBODY;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CLASSIFICATION; CANCER INVASION; CARCINOGENESIS; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; ENDOMETRIUM CARCINOMA; FLOW CYTOMETRY; GENE TARGETING; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LASER DOPPLER FLOWMETRY; LIGHT SCATTERING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIBODIES; CELL SURVIVAL; DNA; ENDOMETRIAL NEOPLASMS; FEMALE; FLOW CYTOMETRY; HUMANS; IMINES; MATRIX METALLOPROTEINASE 2; MOLECULAR STRUCTURE; POLYETHYLENES; TRANSGENES; TUMOR CELLS, CULTURED;

EID: 43049120022     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2007.351     Document Type: Article

References (24)

1. EI-Aneed A. An overview of current delivery systems in cancer gene therapy. J Contr Rel 2004;94:1.
2. Kircheis R, Lionel W, Wagner E. Design and delivery activity of modified polyethylenimine. Adv Drug Deliv Rev 2001;53:341.
3. Fischer D, Bieber T, Li Y, et al. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity. Pharmaceutical Res 1999;168:1273.
4. Kichler A. Gene transfer with modified polyethylenimines. J Gene Medicine 2004;6:S3.
5. Remy J-S, Abdallah B, Zanta MA, et al. Gene transfer with lipospermidines and polyethylenimines. Adv Drug Deliv Rev 1998;30:85.
6. Haensler J, Szoka FC, Jr. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem 1993;4:372.
7. Midoux P, Monsigny M. Efficient gene transfer by histidylated polylysine/pDNA complexes. Bioconjug Chem 1999;10:406.
8. Boussif O, Lezoualc'h F, Znata MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc Natl Acad Sci USA 1995;92:7297.
9. Zaric V, Weltin D, Erbacher P-S, et al. Effective polyehylenimine- mediated gene transfer into human endometrial cells. J Gene Med 2004;6:176.
10. Boussif O, Zanta MA, Behr JP. Optimized galenics improve in vitro gene transfer with cationic molecules up to a thousand-fold. Gene Ther 1996;3:1074.
11. Merdan T, Callahan J, Petersen H, et al. Pegylated polyethylenimine- Fab′ antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells. Bioconjug Chem 2003;14:989.
12. Kichler A, Leborgne C, Coeytaux E, et al. Polyethylenimine-mediated gene delivery: A mechanistic study. J Gene Med 2001;3:135.
13. Erbacher P, Bettinger T, Belguise-Valladier P, et al. Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI). J Gene Med 1999;1:210.
14. Wightman L, Kircheis R, Rossler V, et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med 2001;3:362.
15. Godbey WT, Wu KK, Milos AG. Poly(ethylenimine) and its role in gene delivery. J Contr Rel 1999;60:149.
16. Erbacher P, Remy JS, Behr JP. Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway. Gene Ther 1999;6:138.
17. Kircheis R, Kichler A, Wallner G, et al. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery. Gene Ther 1997;4:409.
18. Park D, Ryu H, Choi D, et al. Localization of matrix metalloproteinases on endometrial cancer cell invasion in vitro. Gynecol Oncol 2001;82:442.
19. Park YH, Ryu HS, Choi DS, et al. Effects of hepatocyte growth factor on the expression of matrix metalloproteinases and their tissue inhibitors during the endometrial cancer invasion in a three-dimensional coculture. Int J Gynecol Cancer 2003;13:53.
20. Kleeman E, Neu M, Jekel N, et al. Nano-carriers for DNA delivery to the lung based upon a TAT-derived peptide covalently coupled to PEG-PEI. J Contr Rel 2005;109:299.
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Meth 1983;65:55.
22. Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 1997;4:823.
23. Moffatti S, Papasakelariou C, Wiehle S, et al. Successful in vivo tumor targeting of prostate-specific membrane antigen with a highly efficient J591/PEI/DNA molecular conjugate. Gene Ther 2006;13:761.
24. Nobs L, Buchegger F, Gurny R, et al. Biodegradable nanoparticles for direct or two-step tumor immunostaining. Bioconjug Chem 2006;17:139.