메뉴 건너뛰기




Volumn 651, Issue 1-2, 2008, Pages 3-13

Mitotic checkpoints and the maintenance of the chromosome karyotype

Author keywords

Aneuploidy; G1 post mitotic checkpoint; Polyploidy; Spindle checkpoint

Indexed keywords

AURORA B KINASE; BOREALIN; CELL PROTEIN; COHESIN; CONDENSIN; CONDENSIN I; CONDENSIN II; DNA TOPOISOMERASE (ATP HYDROLYSING); INCENP PROTEIN; SURVIVIN;

EID: 43049110552     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2007.10.020     Document Type: Article
Times cited : (39)

References (78)
  • 1
    • 0024425887 scopus 로고
    • Checkpoints: control that ensure the order of cell cycle events
    • Hartwell L.H., and Weinert T.A. Checkpoints: control that ensure the order of cell cycle events. Science 246 (1989) 629-634
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 2
    • 0036789555 scopus 로고    scopus 로고
    • The spindle checkpoint: structural insights into dynamic signalling
    • Musacchio A., and Hardwick K.G. The spindle checkpoint: structural insights into dynamic signalling. Nat. Rev. Mol. Cell. Biol. 3 (2002) 731-741
    • (2002) Nat. Rev. Mol. Cell. Biol. , vol.3 , pp. 731-741
    • Musacchio, A.1    Hardwick, K.G.2
  • 4
    • 0032851461 scopus 로고    scopus 로고
    • Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole
    • Verdoodt B., Decordier I., Geleyns K., Cunha M., Cundari E., and Kirsch-Volders M. Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole. Mutagenesis 14 (1999) 513-520
    • (1999) Mutagenesis , vol.14 , pp. 513-520
    • Verdoodt, B.1    Decordier, I.2    Geleyns, K.3    Cunha, M.4    Cundari, E.5    Kirsch-Volders, M.6
  • 5
    • 0028609054 scopus 로고
    • A model of DNA aneuploidization and evolution in colorectal cancer
    • Giaretti W. A model of DNA aneuploidization and evolution in colorectal cancer. Lab. Invest. 71 (1994) 904-910
    • (1994) Lab. Invest. , vol.71 , pp. 904-910
    • Giaretti, W.1
  • 7
    • 0028152736 scopus 로고
    • Aneuploidy for chromosome 1 and overall DNA-content in benign and malignant breast disease
    • Verdoodt B., Castelain Ph., Bourgain C., and Kirsch-Volders M. Aneuploidy for chromosome 1 and overall DNA-content in benign and malignant breast disease. Cancer Genet. Cytogenet. 78 (1994) 53-63
    • (1994) Cancer Genet. Cytogenet. , vol.78 , pp. 53-63
    • Verdoodt, B.1    Castelain, Ph.2    Bourgain, C.3    Kirsch-Volders, M.4
  • 9
    • 0035180041 scopus 로고    scopus 로고
    • Predictors of progression in Barrett's esophagus III: baseline flow cytometric variables
    • Rabinovitch P.S., Longton G., Blount P.L., Levine D.S., and Reid B.J. Predictors of progression in Barrett's esophagus III: baseline flow cytometric variables. Am. J. Gastroenterol. 96 (2001) 3071-3083
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 3071-3083
    • Rabinovitch, P.S.1    Longton, G.2    Blount, P.L.3    Levine, D.S.4    Reid, B.J.5
  • 13
    • 4544315452 scopus 로고    scopus 로고
    • Mechanisms and molecules of the mitotic spindle
    • Gadde S., and Heald R. Mechanisms and molecules of the mitotic spindle. Curr. Biol. 14 (2004) R797-R805
    • (2004) Curr. Biol. , vol.14
    • Gadde, S.1    Heald, R.2
  • 14
    • 4143066950 scopus 로고    scopus 로고
    • Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics
    • Kline-Smith S.L., and Walczak C.E. Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics. Mol. Cell. 15 (2004) 317-327
    • (2004) Mol. Cell. , vol.15 , pp. 317-327
    • Kline-Smith, S.L.1    Walczak, C.E.2
  • 15
    • 0037349338 scopus 로고    scopus 로고
    • The making of the mitotic chromosome: modern insights into classical questions
    • Swedlow J.R., and Hirano T. The making of the mitotic chromosome: modern insights into classical questions. Mol. Cell. 1 (2003) 557-569
    • (2003) Mol. Cell. , vol.1 , pp. 557-569
    • Swedlow, J.R.1    Hirano, T.2
  • 16
    • 0032191345 scopus 로고    scopus 로고
    • Facilitation of chromatin dynamics by SARs
    • Hart C.M., and Laemmli U.K. Facilitation of chromatin dynamics by SARs. Curr. Opin. Genet. Dev. 8 (1998) 519-525
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 519-525
    • Hart, C.M.1    Laemmli, U.K.2
  • 19
    • 0242383489 scopus 로고    scopus 로고
    • Dynamic interactions of nuclear lamina proteins with chromatin and transcriptional machinery
    • Mattout-Drubezki A., and Gruenbaum Y. Dynamic interactions of nuclear lamina proteins with chromatin and transcriptional machinery. Cell. Mol. Life Sci. 60 (2003) 2053-2063
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 2053-2063
    • Mattout-Drubezki, A.1    Gruenbaum, Y.2
  • 20
    • 0032189942 scopus 로고    scopus 로고
    • Investigating the biological functions of DNA topoisomerases in eukaryotic cells
    • Nitiss J.L. Investigating the biological functions of DNA topoisomerases in eukaryotic cells. Biochim. Biophys. Acta 1400 (1998) 63-81
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 63-81
    • Nitiss, J.L.1
  • 21
    • 13544254815 scopus 로고    scopus 로고
    • Topoisomerase II: untangling its contribution at the centromere
    • Porter A.C.G., and Farr C.J. Topoisomerase II: untangling its contribution at the centromere. Chrom. Res. 12 (2004) 569-583
    • (2004) Chrom. Res. , vol.12 , pp. 569-583
    • Porter, A.C.G.1    Farr, C.J.2
  • 22
    • 0345060775 scopus 로고    scopus 로고
    • Building and breaking bridges between sister chromatids
    • Haering C.H., and Nasmyth K. Building and breaking bridges between sister chromatids. BioEssays 25 (2003) 1178-1191
    • (2003) BioEssays , vol.25 , pp. 1178-1191
    • Haering, C.H.1    Nasmyth, K.2
  • 23
    • 0033821376 scopus 로고    scopus 로고
    • A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homologue of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation
    • Schmiesing J.A., Gregson H.C., Zhou S., and Yokomori K. A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homologue of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation. Mol. Cell. Biol. 20 (2000) 6996-7006
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6996-7006
    • Schmiesing, J.A.1    Gregson, H.C.2    Zhou, S.3    Yokomori, K.4
  • 24
    • 17144390295 scopus 로고    scopus 로고
    • Condensins: organizing and segregating the genome
    • Hirano T. Condensins: organizing and segregating the genome. Curr. Biol. 15 (2005) R265-R275
    • (2005) Curr. Biol. , vol.15
    • Hirano, T.1
  • 26
    • 12344296753 scopus 로고    scopus 로고
    • Heterochromatin-many flavours, common themes
    • Craig J.M. Heterochromatin-many flavours, common themes. Bioessays 27 (2005) 17-28
    • (2005) Bioessays , vol.27 , pp. 17-28
    • Craig, J.M.1
  • 27
    • 2142809838 scopus 로고    scopus 로고
    • Assembly of kinetochores in vertebrate cells
    • Fukagawa T. Assembly of kinetochores in vertebrate cells. Exp. Cell. Res. 296 (2004) 21-27
    • (2004) Exp. Cell. Res. , vol.296 , pp. 21-27
    • Fukagawa, T.1
  • 28
    • 7744222944 scopus 로고    scopus 로고
    • Chromosomal passengers: the four-dimensional regulation of mitotic events
    • Vagnarelli P., and Earnshaw W.C. Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma 113 (2004) 211-222
    • (2004) Chromosoma , vol.113 , pp. 211-222
    • Vagnarelli, P.1    Earnshaw, W.C.2
  • 29
    • 0346727135 scopus 로고    scopus 로고
    • Passenger acrobatics
    • Higuchi T., and Uhlmann F. Passenger acrobatics. Nature 426 (2003) 780-781
    • (2003) Nature , vol.426 , pp. 780-781
    • Higuchi, T.1    Uhlmann, F.2
  • 30
    • 0035478337 scopus 로고    scopus 로고
    • The centrosome in vertebrates: more than a microtubule-organizing center
    • Rieder C.L., Faruki S., and Khodjakov A. The centrosome in vertebrates: more than a microtubule-organizing center. Trends Cell Biol. 11 (2001) 413-419
    • (2001) Trends Cell Biol. , vol.11 , pp. 413-419
    • Rieder, C.L.1    Faruki, S.2    Khodjakov, A.3
  • 32
    • 0035462382 scopus 로고    scopus 로고
    • Re-evaluating centrosome function
    • Doxsey S. Re-evaluating centrosome function. Nat. Rev. Mol. Cell Biol. 2 (2001) 688-698
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 688-698
    • Doxsey, S.1
  • 33
    • 0035936920 scopus 로고    scopus 로고
    • Centrosome-dependent exit of cytokinesis in animal cells
    • Piel M., Nordberg J., Euteneuer U., and Bornens M. Centrosome-dependent exit of cytokinesis in animal cells. Science 291 (2001) 1550-1553
    • (2001) Science , vol.291 , pp. 1550-1553
    • Piel, M.1    Nordberg, J.2    Euteneuer, U.3    Bornens, M.4
  • 35
    • 0033145516 scopus 로고    scopus 로고
    • Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
    • Meraldi P., Lukas J., Fry A.M., Bartek J., and Nigg E.A. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat. Cell. Biol. 1 (1999) 88-93
    • (1999) Nat. Cell. Biol. , vol.1 , pp. 88-93
    • Meraldi, P.1    Lukas, J.2    Fry, A.M.3    Bartek, J.4    Nigg, E.A.5
  • 37
    • 3342973782 scopus 로고    scopus 로고
    • p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation
    • Tritarelli A., Oricchio E., Ciciarello M., Mangiacasale R., Palena A., Lavia P., Soddu S., and Cundari E. p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation. Mol. Biol. Cell 15 (2004) 3751-3757
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3751-3757
    • Tritarelli, A.1    Oricchio, E.2    Ciciarello, M.3    Mangiacasale, R.4    Palena, A.5    Lavia, P.6    Soddu, S.7    Cundari, E.8
  • 38
    • 0036831681 scopus 로고    scopus 로고
    • Centrosome aberrations: cause or consequence of cancer progression?
    • Nigg E.A. Centrosome aberrations: cause or consequence of cancer progression?. Nat. Rev. Cancer 2 (2002) 815-825
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 815-825
    • Nigg, E.A.1
  • 39
    • 4444224967 scopus 로고    scopus 로고
    • Vertebrate Shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis
    • Salic A., Waters J.C., and Mitchison T.J. Vertebrate Shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell 118 (2004) 567-578
    • (2004) Cell , vol.118 , pp. 567-578
    • Salic, A.1    Waters, J.C.2    Mitchison, T.J.3
  • 40
    • 0036902234 scopus 로고    scopus 로고
    • Regulation of APC-Cdc20 by the spindle checkpoint
    • Yu H. Regulation of APC-Cdc20 by the spindle checkpoint. Curr. Opin. Cell Biol. 14 (2002) 706-714
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 706-714
    • Yu, H.1
  • 41
    • 0034721669 scopus 로고    scopus 로고
    • Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast
    • Uhlmann F., Wernic D., Poupart M.A., Koonin E.V., and Nasmyth K. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103 (2000) 375-386
    • (2000) Cell , vol.103 , pp. 375-386
    • Uhlmann, F.1    Wernic, D.2    Poupart, M.A.3    Koonin, E.V.4    Nasmyth, K.5
  • 42
    • 0035861914 scopus 로고    scopus 로고
    • Dual inhibition of sister chromatid separation at metaphase
    • Stemmann O., Zou H., Gerber S.A., Gygi S.P., and Kirschner M.W. Dual inhibition of sister chromatid separation at metaphase. Cell 107 (2001) 715-726
    • (2001) Cell , vol.107 , pp. 715-726
    • Stemmann, O.1    Zou, H.2    Gerber, S.A.3    Gygi, S.P.4    Kirschner, M.W.5
  • 43
    • 1842486792 scopus 로고    scopus 로고
    • The spindle checkpoint, aneuploidy, and cancer
    • Bharadwaj R., and Hu Y. The spindle checkpoint, aneuploidy, and cancer. Oncogene 23 (2004) 2016-2027
    • (2004) Oncogene , vol.23 , pp. 2016-2027
    • Bharadwaj, R.1    Hu, Y.2
  • 45
    • 24344439888 scopus 로고    scopus 로고
    • The spindle checkpoint: tension versus attachment
    • Pinsky B.A., and Biggins S. The spindle checkpoint: tension versus attachment. Trends Cell Biol. 15 (2005) 486-493
    • (2005) Trends Cell Biol. , vol.15 , pp. 486-493
    • Pinsky, B.A.1    Biggins, S.2
  • 46
    • 0035211559 scopus 로고    scopus 로고
    • Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential
    • Nicklas R.B., Waters J.C., Salmon E.D., and Ward S.C. Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential. J. Cell. Sci. 114 (2001) 4173-4183
    • (2001) J. Cell. Sci. , vol.114 , pp. 4173-4183
    • Nicklas, R.B.1    Waters, J.C.2    Salmon, E.D.3    Ward, S.C.4
  • 47
    • 0023678444 scopus 로고
    • Monoclonal antibodies specific for thiophosphorylated proteins recognize Xenopus MPF
    • Cyert M.S., Scherson T., and Kirschner M.W. Monoclonal antibodies specific for thiophosphorylated proteins recognize Xenopus MPF. Dev. Biol. 129 (1988) 209-216
    • (1988) Dev. Biol. , vol.129 , pp. 209-216
    • Cyert, M.S.1    Scherson, T.2    Kirschner, M.W.3
  • 49
    • 0027303640 scopus 로고
    • Differential expression of a phosphoepitope at the kinetochores of moving chromosomes
    • Gorbsky G.J., and Ricketts W.A. Differential expression of a phosphoepitope at the kinetochores of moving chromosomes. J. Cell. Biol. 122 (1993) 1311-1321
    • (1993) J. Cell. Biol. , vol.122 , pp. 1311-1321
    • Gorbsky, G.J.1    Ricketts, W.A.2
  • 50
    • 20544449744 scopus 로고    scopus 로고
    • Polo-like Kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores
    • Ahonen L.J., Kallio M.J., Daum J.R., Bolton M., Manke I.A., Yaffe M.B., Stukenberg P.T., and Gorbsky G.J. Polo-like Kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr. Biol. 15 (2005) 1078-1089
    • (2005) Curr. Biol. , vol.15 , pp. 1078-1089
    • Ahonen, L.J.1    Kallio, M.J.2    Daum, J.R.3    Bolton, M.4    Manke, I.A.5    Yaffe, M.B.6    Stukenberg, P.T.7    Gorbsky, G.J.8
  • 51
    • 0037173425 scopus 로고    scopus 로고
    • Importance of detecting numerical versus structural chromosome aberrations
    • Kirsch-Volders M., Vanhauwaert A., De Boeck M., and Decordier I. Importance of detecting numerical versus structural chromosome aberrations. Mutat. Res. 504 (2002) 137-148
    • (2002) Mutat. Res. , vol.504 , pp. 137-148
    • Kirsch-Volders, M.1    Vanhauwaert, A.2    De Boeck, M.3    Decordier, I.4
  • 55
    • 4644281946 scopus 로고    scopus 로고
    • Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
    • Vogel C., Kienitz A., Hofmann I., Muller R., and Bastians H. Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene 23 (2004) 6845-6853
    • (2004) Oncogene , vol.23 , pp. 6845-6853
    • Vogel, C.1    Kienitz, A.2    Hofmann, I.3    Muller, R.4    Bastians, H.5
  • 56
    • 33645324468 scopus 로고    scopus 로고
    • ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity
    • Oricchio E., Saladino C., Iacovelli S., Soddu S., and Cundari E. ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity. Cell Cycle 5 (2006) 88-92
    • (2006) Cell Cycle , vol.5 , pp. 88-92
    • Oricchio, E.1    Saladino, C.2    Iacovelli, S.3    Soddu, S.4    Cundari, E.5
  • 57
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3 (2003) 155-168
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 59
    • 0029590246 scopus 로고
    • Indications for a threshold of chemically induced aneuploidy in vitro in human lymphocytes
    • Elhajouji A., Van Hummelen P., and Kirsch-Volders M. Indications for a threshold of chemically induced aneuploidy in vitro in human lymphocytes. Environ. Mol. Mutagen. 26 (1995) 292-304
    • (1995) Environ. Mol. Mutagen. , vol.26 , pp. 292-304
    • Elhajouji, A.1    Van Hummelen, P.2    Kirsch-Volders, M.3
  • 60
    • 0030985954 scopus 로고    scopus 로고
    • Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes
    • Elhajouji A., Tibaldi F., and Kirsch-Volders M. Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. Mutagenesis 12 (1997) 133-140
    • (1997) Mutagenesis , vol.12 , pp. 133-140
    • Elhajouji, A.1    Tibaldi, F.2    Kirsch-Volders, M.3
  • 61
    • 0033651660 scopus 로고    scopus 로고
    • Changes in microtubule organization after exposure to a benzimidazole derivative in Chinese hamster cells
    • Pisano C., Battistoni A., Antoccia A., Degrassi F., and Tanzarella C. Changes in microtubule organization after exposure to a benzimidazole derivative in Chinese hamster cells. Mutagenesis 15 (2000) 507-515
    • (2000) Mutagenesis , vol.15 , pp. 507-515
    • Pisano, C.1    Battistoni, A.2    Antoccia, A.3    Degrassi, F.4    Tanzarella, C.5
  • 62
    • 14644403089 scopus 로고    scopus 로고
    • Non-invasive method to assess genotoxicity of nocodazole interfering with spindle formation in mammalian oocytes
    • Shen Y., Betzendahl I., Sun F., Tinneberg H.R., and Eichenlaub-Ritter U. Non-invasive method to assess genotoxicity of nocodazole interfering with spindle formation in mammalian oocytes. Reprod. Toxicol. 19 (2005) 459-471
    • (2005) Reprod. Toxicol. , vol.19 , pp. 459-471
    • Shen, Y.1    Betzendahl, I.2    Sun, F.3    Tinneberg, H.R.4    Eichenlaub-Ritter, U.5
  • 63
    • 0041883657 scopus 로고    scopus 로고
    • Mutations and aneuploidy: co-conspirators in cancer?
    • Pihan G., and Doxsey S.J. Mutations and aneuploidy: co-conspirators in cancer?. Cancer Cell 4 (2003) 89-94
    • (2003) Cancer Cell , vol.4 , pp. 89-94
    • Pihan, G.1    Doxsey, S.J.2
  • 64
    • 10944269112 scopus 로고    scopus 로고
    • Centrosomal amplification and spindle multipolarity in cancer cells
    • Saunders W. Centrosomal amplification and spindle multipolarity in cancer cells. Semin. Cancer Biol. 15 (2005) 25-32
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 25-32
    • Saunders, W.1
  • 65
    • 0037018844 scopus 로고    scopus 로고
    • Inhibtion of Aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis
    • Kallio M.J., Mc Cleland M.L., Stukenberg P.T., and Gorbsky G.J. Inhibtion of Aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr. Biol. 12 (2002) 900-905
    • (2002) Curr. Biol. , vol.12 , pp. 900-905
    • Kallio, M.J.1    Mc Cleland, M.L.2    Stukenberg, P.T.3    Gorbsky, G.J.4
  • 67
    • 0032478547 scopus 로고    scopus 로고
    • Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
    • Jin D.Y., Spencer F., and Jeang K.T. Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93 (1998) 81-91
    • (1998) Cell , vol.93 , pp. 81-91
    • Jin, D.Y.1    Spencer, F.2    Jeang, K.T.3
  • 68
    • 3142761931 scopus 로고    scopus 로고
    • Chromosomal aberrations and genomic instability induced by topoiomerase-targeted antitumour drugs
    • Degrassi F., Fiore M., and Palitti F. Chromosomal aberrations and genomic instability induced by topoiomerase-targeted antitumour drugs. Curr. Med. Chem. Anti-Cancer Agents 4 (2004) 317-325
    • (2004) Curr. Med. Chem. Anti-Cancer Agents , vol.4 , pp. 317-325
    • Degrassi, F.1    Fiore, M.2    Palitti, F.3
  • 71
    • 0033533731 scopus 로고    scopus 로고
    • Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification
    • Tutt A., Gabriel A., Bertwistle D., Connor F., Paterson H., Peacock J., Ross G., and Ashworth A. Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr. Biol. 9 (1999) 1107-1110
    • (1999) Curr. Biol. , vol.9 , pp. 1107-1110
    • Tutt, A.1    Gabriel, A.2    Bertwistle, D.3    Connor, F.4    Paterson, H.5    Peacock, J.6    Ross, G.7    Ashworth, A.8
  • 72
    • 0036675318 scopus 로고    scopus 로고
    • Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer
    • Weaver Z., Montagna C., Xu X., Howard T., Gadina M., Brodie S.G., Deng C.X., and Ried T. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer. Oncogene 21 (2002) 5097-5107
    • (2002) Oncogene , vol.21 , pp. 5097-5107
    • Weaver, Z.1    Montagna, C.2    Xu, X.3    Howard, T.4    Gadina, M.5    Brodie, S.G.6    Deng, C.X.7    Ried, T.8
  • 73
    • 0033575347 scopus 로고    scopus 로고
    • Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
    • Zou H., McGarry T.J., Bernal T., and Kirschner M.W. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science 285 (1999) 418-422
    • (1999) Science , vol.285 , pp. 418-422
    • Zou, H.1    McGarry, T.J.2    Bernal, T.3    Kirschner, M.W.4
  • 76
    • 0004289980 scopus 로고
    • Zur Frage der Entstehung Maligner Tumouren, Gustav Fisher
    • Boveri T. Zur Frage der Entstehung Maligner Tumouren, Gustav Fisher. Jena (1914) 1-64
    • (1914) Jena , pp. 1-64
    • Boveri, T.1
  • 77
    • 0034525948 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Sen S. Aneuploidy and cancer. Curr. Opin. Oncol. 12 (2000) 82-88
    • (2000) Curr. Opin. Oncol. , vol.12 , pp. 82-88
    • Sen, S.1
  • 78
    • 10044286199 scopus 로고    scopus 로고
    • Aneuploidy and malignancy: an unsolved equation
    • Dey P. Aneuploidy and malignancy: an unsolved equation. J. Clin. Pathol. 57 (2005) 1245-1249
    • (2005) J. Clin. Pathol. , vol.57 , pp. 1245-1249
    • Dey, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.