Functional structure of adipocytes differentiated from human umbilical cord stroma-derived stem cells

Stem Cells

Volumn 26, Issue 3, 2008, Pages 682-691

  Karahuseyinoglu, Sercin ^a   Kocaefe, Cetin ^b   Balci, Deniz ^a   Erdemli, Esra ^a   Can, Alp ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Adipocyte; Differentiation; Human; Lipid; Mesenchymal stem cells; Umbilical cord

Indexed keywords

ACYL COENZYME A DESATURASE; ADIPONECTIN; ADIPOPHILIN; CCAAT ENHANCER BINDING PROTEIN BETA; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE 1; HORMONE SENSITIVE LIPASE; LEPTIN; MESSENGER RNA; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG; ACTIN; BIOLOGICAL MARKER;

ADIPOCYTE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; FETUS; HUMAN; HUMAN CELL; STEM CELL; STROMA; UMBILICAL CORD; UMBILICAL CORD STROMA DERIVED STEM CELL; ADIPOGENESIS; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIPID METABOLISM; METABOLISM; STROMA CELL; TIME; ULTRASTRUCTURE;

ACTINS; ADIPOCYTES; ADIPOGENESIS; BIOLOGICAL MARKERS; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; RNA, MESSENGER; STEM CELLS; STROMAL CELLS; TIME FACTORS; UMBILICAL CORD;

EID: 43049087468     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0738     Document Type: Article

References (60)

1. Mitchell KE, Weiss ML, Mitchell BM et al. Matrix cells from Wharton's jelly form neurons and glia. STEM CELLS 2003;21:50-60.
2. Ma L, Feng XY, Cui BL et al. Human umbilical cord Wharton's Jelly-derived mesenchymal stem cells differentiation into nerve-like cells. Chin Med J (Engl) 2005;118:1987-1993.
3. Fu YS, Shih YT, Cheng YC et al. Transformation of human umbilical mesenchymal cells into neurons in vitro. J Biomed Sci 2004;11:652-660.
4. Karahuseyinoglu S, Cinar O, Kilic E et al. Biology of stem cells in human umbilical cord stroma: In situ and in vitro surveys. STEM CELLS 2007;25:319-331.
5. Wang HS, Hung SC, Peng ST et al. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. STEM CELLS 2004;22:1330-1337.
6. Conconi MT, Burra P, Di Liddo R et al. CD105(+) cells from Wharton's jelly show in vitro and in vivo myogenic differentiative potential. Int J Mol Med 2006;18:1089-1096.
7. Baksh D, Yao R, Tuan RS. Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow. STEM CELLS 2007;25:1384-1392.
8. Kim JW, Kim SY, Park SY et al. Mesenchymal progenitor cells in the human umbilical cord. Ann Hematol 2004;83:733-738.
9. Lu LL, Liu YJ, Yang SG et al. Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica 2006;91:1017-1026.
10. Rosen ED, Walkey CJ, Puigserver P et al. Transcriptional regulation of adipogenesis. Genes Dev 2000;14:1293-1307.
11. Hansen JB, Zhang H, Rasmussen TH et al. Peroxisome proliferator-activated receptor delta (PPARdelta)-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling. J Biol Chem 2001;276:3175-3182.
12. Kocaefe YC, Israeli D, Ozguc M et al. Myogenic program induction in mature fat tissue (with MyoD expression). Exp Cell Res 2005;308:300-308.
13. Porstmann T, Griffiths B, Chung YL et al. PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene 2005;24:6465-6481.
14. Fève B. Adipogenesis: Cellular and molecular aspects. Best Pract Res Clin Endocrinol Metab 2005;19:483-499.
15. Boone C, Mourot J, Gregoire F et al. The adipose conversion process: Regulation by extracellular and intracellular factors. Reprod Nutr Dev 2000;40:325-358.
16. Spiegelman BM, Farmer SR. Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3 adipocytes. Cell 1982;29:53-60.
17. Mueller E, Drori S, Aiyer A et al. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. J Biol Chem 2002;277:41925-41930.
18. Musri MM, Corominola H, Casamitjana R et al. Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes. J Biol Chem 2006;281:17180-17188.
19. Klein S, Coppack SW, Mohamed-Ali V et al. Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes 1996;45:984-987.
20. Fu Y, Luo N, Klein RL et al. Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 2005;46:1369-1379.
21. Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
22. Teboul L, Febbraio M, Gaillard D et al. Structural and functional characterization of the mouse fatty acid translocase promoter: Activation during adipose differentiation. Biochem J 2001;360:305-312.
23. Csete M, Walikonis J, Slawny N et al. Oxygen-mediated regulation of skeletal muscle satellite cell proliferation and adipogenesis in culture. J Cell Physiol 2001;189:189-196.
24. Dani C, Smith AG, Dessolin S et al. Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci 1997;110:1279-1285.
25. Can A, Karahuseyinoglu S. Concise review: Human umbilical cord stroma with regard to the source of fetus-derived stem cells. STEM CELLS 2007;25:2886-2895.
26. Dennis JE, Merriam A, Awadallah A et al. A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse. J Bone Miner Res 1999;14:700-709.
27. Olcay L, Erdemli E, Kesimer M et al. High cystine in platelets from patients with nephropathic cystinosis: A chemical, ultrastructural, and functional evaluation. J Clin Pathol 2005;58:939-945.
28. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
29. Vandesompele J, De Preter K, Pattyn F et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:RESEARCH0034.
30. Yamaguchi T, Omatsu N, Omukae A et al. Analysis of interaction partners for perilipin and ADRP on lipid droplets. Mol Cell Biochem 2006;284:167-173.
31. Mackay DL, Tesar PJ, Liang LN et al. Characterizing medullary and human mesenchymal stem cell-derived adipocytes. J Cell Physiol 2006;207:722-728.
32. Sekiya I, Larson BL, Vuoristo JT et al. Adipogenic differentiation of human adult stem cells from bone marrow stroma (MSCs). J Bone Miner Res 2004;19:256-264.
33. Janderov á L, McNeil M, Murrell AN et al. Human mesenchymal stem cells as an in vitro model for human adipogenesis. Obes Res 2003;11:65-74.
34. Yen BL, Huang HI, Chien CC et al. Isolation of multipotent cells from human term placenta. STEM CELLS 2005;23:3-9.
35. In 't Anker PS, Scherjon SA, Kleijburg-van der Keur C et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. STEM CELLS 2004;22:1338-1345.
36. Chang YJ, Shih DT, Tseng CP et al. Disparate mesenchyme-lineage tendencies in mesenchymal stem cells from human bone marrow and umbilical cord blood. STEM CELLS 2006;24:679-685.
37. Erices A, Conget P, Minguell JJ. Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 2000;109:235-242.
38. Kadivar M, Khatami S, Mortazavi Y et al. In vitro cardiomyogenic potential of human umbilical vein-derived mesenchymal stem cells. Biochem Biophys Res Commun 2006;340:639-647.
39. Sengenès C, Lolmede K, Zakaroff-Girard A et al. Preadipocytes in the human subcutaneous adipose tissue display distinct features from the adult mesenchymal and hematopoietic stem cells. J Cell Physiol 2005;205:114-122.
40. Mauney JR, Volloch V, Kaplan DL. Matrix-mediated retention of adipogenic differentiation potential by human adult bone marrow-derived mesenchymal stem cells during ex vivo expansion. Biomaterials 2005;26:6167-6175.
41. Katz AJ, Llull R, Hedrick MH et al. Emerging approaches to the tissue engineering of fat. Clin Plast Surg 1999;26:587-603, viii.
42. Rubin CS, Hirsch A, Fung C et al. Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J Biol Chem 1978;253:7570-7578.
43. Smas CM, Sul HS. Control of adipocyte differentiation. Biochem J 1995;309(Pt 3):697-710.
44. Gregoire FM. Adipocyte differentiation: From fibroblast to endocrine cell. Exp Biol Med (Maywood) 2001;226:997-1002.
45. Avram MM, Avram AS, James WD. Subcutaneous fat in normal and diseased states 3. Adipogenesis: From stem cell to fat cell. J Am Acad Dermatol 2007;56:472-492.
46. Nakamura T, Shiojima S, Hirai Y et al. Temporal gene expression changes during adipogenesis in human mesenchymal stem cells. Biochem Biophys Res Commun 2003;303:306-312.
47. Hausman DB, DiGirolamo M, Bartness TJ et al. The biology of white adipocyte proliferation. Obes Rev 2001;2:239-254.
48. Entenmann G, Hauner H. Relationship between replication and differentiation in cultured human adipocyte precursor cells. Am J Physiol 1996;270:C1011-1016.
49. Novikoff AB, Novikoff PM, Rosen OM et al. Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol 1980;87:180-196.
50. Sidhu RS. Two-dimensional electrophoretic analyses of proteins synthesized during differentiation of 3T3-L1 preadipocytes. J Biol Chem 1979;254:11111-11118.
51. Rosen ED, Hsu CH, Wang X et al. C/EBPalpha induces adipogenesis through PPARgamma: A unified pathway. Genes Dev 2002;16:22-26.
52. Brasaemle DL, Barber T, Wolins NE et al. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 1997;38:2249-2263.
53. Wise LS, Green H. Participation of one isozyme of cytosolic glycerophosphate dehydrogenase in the adipose conversion of 3T3 cells. J Biol Chem 1979;254:273-275.
54. Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia 2003;46:1594-1603.
55. Combs TP, Wagner JA, Berger J et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: A potential mechanism of insulin sensitization. Endocrinology 2002;143:998-1007.
56. Parry EW. Some electron microscope observations on the mesenchymal structures of full-term umbilical cord. J Anat 1970;107:505-518.
57. Kobayashi K, Kubota T, Aso T. Study on myofibroblast differentiation in the stromal cells of Wharton's jelly: Expression and localization of alpha-smooth muscle actin. Early Hum Dev 1998;51:223-233.
58. Nanaev AK, Kohnen G, Milovanov AP et al. Stromal differentiation and architecture of the human umbilical cord. Placenta 1997;18:53-64.
59. Takechi K, Kuwabara Y, Mizuno M. Ultrastructural and immunohistochemical studies of Wharton's jelly umbilical cord cells. Placenta 1993;14:235-245.
60. Weiss ML, Medicetty S, Bledsoe AR et al. Human umbilical cord matrix stem cells: Preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. STEM CELLS 2006;24:781-792.