Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells

British Journal of Pharmacology

Volumn 154, Issue 1, 2008, Pages 246-255

  Haslam, I S ^a   Jones, K ^b   Coleman, T ^b   Simmons, N L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Constitutive androstane receptor; Digoxin; Induction; P glycoprotein; Pregnane X receptor; Rifampin; T84 cells

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; DIGOXIN; MULTIDRUG RESISTANCE PROTEIN 1; PREGNANE X RECEPTOR; RIFAMPICIN;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE TRANSPORT; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; TRANSPORT KINETICS;

EID: 42949127617     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.69     Document Type: Article

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