New tetrazole-based selective anandamide uptake inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 9, 2008, Pages 2820-2824

  Ortar, Giorgio ^a   Schiano Moriello, Aniello ^b   Cascio, Maria Grazia ^b   De Petrocellis, Luciano ^c   Ligresti, Alessia ^b   Morera, Enrico ^a   Nalli, Marianna ^a   Di Marzo, Vincenzo ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c CNR   (Italy)

Author keywords

Anandamide uptake; Anandamide uptake inhibitors; Endocannabinoids; Tetrazoles

Indexed keywords

ANANDAMIDE; ENDOCANNABINOID; TETRAZOLE DERIVATIVE;

ANALYTIC METHOD; ARTICLE; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50;

ALKYLATION; ANIMALS; ARACHIDONIC ACIDS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; POLYUNSATURATED ALKAMIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES;

EID: 42949106606     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.04.003     Document Type: Article

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