Preparation and NMR spectroscopic studies of the glucuronides of Irbesartan

Tetrahedron

Volumn 55, Issue 18, 1999, Pages 5931-5936

  Byard, Stephen J ^a   Herbert, John M ^b  

^a Sanofi Synthelabo Inc   (United Kingdom)

^b Sanofi Research Division   (United Kingdom)

Author keywords

13C 1H correlation; Angiotensin II antagonist; nOe enhancement; Tetrazole glucuronide

Indexed keywords

ANGIOTENSIN II ANTAGONIST; GLUCURONIDE; IRBESARTAN; TETRAZOLE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DATA ANALYSIS; DRUG POTENCY; DRUG SYNTHESIS; GLUCURONIDATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 0033617373     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(99)00255-0     Document Type: Article

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15. 11. Calculations were carried out using the Amber forcefield in Macromodel.™