Escherichia coli RNase P RNA: Substrate Ribose Modifications at G+1, but Not Nucleotide - 1/+73 Base Pairing, Affect the Transition State for Cleavage Chemistry

Journal of Molecular Biology

Volumn 379, Issue 1, 2008, Pages 1-8

  Cuzic, Simona ^a   Heidemann, Karin Abarca ^b   Wöhnert, Jens ^b   Hartmann, Roland K ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Escherichia coli RNase P; locked nucleic acid (LNA) or 2 OCH3 substitutions at G+1 in the substrate; NMR analysis of acceptor stem mimics; precursor tRNA processing

Indexed keywords

ESTER DERIVATIVE; LOCKED NUCLEIC ACID; NUCLEOTIDE; PHOSPHODIESTER; RIBONUCLEASE; TRANSFER RNA;

ARTICLE; BASE PAIRING; ENTROPY; ENZYME MODIFICATION; ESCHERICHIA COLI; GENE INTERACTION; HYDROGEN BOND; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RNA CLEAVAGE; SUBSTITUTION REACTION; TEMPERATURE DEPENDENCE;

ESCHERICHIA COLI;

EID: 42749095670     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.03.042     Document Type: Article

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