Activation of sphingosine kinase mediates suppressive effect of interleukin-6 on human multiple myeloma cell apoptosis

British Journal of Haematology

Volumn 138, Issue 5, 2007, Pages 632-639

  Li, Qing Fang ^a   Wu, Chu Tse ^a   Duan, Hai Feng ^a   Sun, Hui Yan ^a   Wang, Hua ^a   Lu, Zhuo Zhuang ^a   Zhang, Qun Wei ^a   Liu, Hong Jun ^a   Wang, Li Sheng ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Apoptosis; Interleukin 6; Multiple myeloma; RNA interference; Sphingosine kinase

Indexed keywords

DEXAMETHASONE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; SPINGOSINE KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL PROLIFERATION; DEXAMETHASONE; ENZYME ACTIVATION; GLUCOCORTICOIDS; HUMANS; INTERLEUKIN-6; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MULTIPLE MYELOMA; NEOPLASM PROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 34547647448     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06711.x     Document Type: Article

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