O-GlcNAc modification of FoxO1 increases its transcriptional activity: A role in the glucotoxicity phenomenon?

Biochimie

Volumn 90, Issue 5, 2008, Pages 679-685

  Kuo, MeiShiue ^a,b   Zilberfarb, Vladimir ^a,b   Gangneux, Nicolas ^a,b   Christeff, Névéna ^a,b   Issad, Tarik ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

Author keywords

Diabetes; Glucose 6 phosphatase; Glucotoxicity; O Glycosylation; PGC1

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATASE; HEXOSAMINE; LUCIFERASE; N ACETYLGLUCOSAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR FKHR;

APOPTOSIS; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEGLYCOSYLATION; DIABETES MELLITUS; DNA BINDING; GLYCOSYLATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN RESISTANCE; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REPORTER GENE; REVIEW; TRANSCRIPTION REGULATION;

ACETYLGLUCOSAMINE; CELL LINE; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE-6-PHOSPHATASE; HUMANS; TRANSCRIPTION, GENETIC;

EID: 42649105106     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2008.03.005     Document Type: Review

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