메뉴 건너뛰기




Volumn 28, Issue 2 B, 2008, Pages 1303-1308

Present treatment and future expectations in advanced pancreatic cancer

Author keywords

Pancreatic cancer status; Review

Indexed keywords

CAPECITABINE; CETUXIMAB; CISPLATIN; DOCETAXEL; ERLOTINIB; GEMCITABINE; IRINOTECAN; OXALIPLATIN; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RALTITREXED; RUBITECAN; TAXANE DERIVATIVE; TIPIFARNIB; TOPOTECAN; TRASTUZUMAB; UNCLASSIFIED DRUG; ZANESTRA;

EID: 42549085643     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (21)

References (60)
  • 1
    • 0001614379 scopus 로고
    • Cancer of the pancreas
    • DeVita VT Jr, Hellman S, Rosenberg SA eds, 4th edition, Lippincott, Philadelphia, PA, pp
    • Brenna MF, Kinsella TJ and Casper ES: Cancer of the pancreas. In: Cancer, principles and practice of oncology. DeVita VT Jr, Hellman S, Rosenberg SA (eds.). 4th edition, Lippincott, Philadelphia, PA, pp. 849-882, 1993.
    • (1993) Cancer, principles and practice of oncology , pp. 849-882
    • Brenna, M.F.1    Kinsella, T.J.2    Casper, E.S.3
  • 2
    • 0029874268 scopus 로고    scopus 로고
    • Chemotherapy of adenocarcinoma of the pancreas
    • Schnall SF and Macdonald JS: Chemotherapy of adenocarcinoma of the pancreas. Semin Oncol 23: 220-228, 1996.
    • (1996) Semin Oncol , vol.23 , pp. 220-228
    • Schnall, S.F.1    Macdonald, J.S.2
  • 3
    • 0031601404 scopus 로고    scopus 로고
    • Gemcitabine: A new approach to treating pancreatic cancer
    • Stephens CD: Gemcitabine: a new approach to treating pancreatic cancer. Oncol Nurs Forum 25: 87-93, 1998.
    • (1998) Oncol Nurs Forum , vol.25 , pp. 87-93
    • Stephens, C.D.1
  • 4
    • 0028292341 scopus 로고
    • Phase II trial of gemcitabine (2.2 difluorodeoxytidine) in patients with adenocarcinoma of the pancreas
    • Casper ES, Green MR and Kelsen DP: Phase II trial of gemcitabine (2.2 difluorodeoxytidine) in patients with adenocarcinoma of the pancreas. Invest New Drugs 12: 29-34, 1994.
    • (1994) Invest New Drugs , vol.12 , pp. 29-34
    • Casper, E.S.1    Green, M.R.2    Kelsen, D.P.3
  • 13
    • 0033368083 scopus 로고    scopus 로고
    • Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small-cell lung cancer cell lines
    • Bahadori HR, Rocha-Lima CM, Green MR and Safa AR: Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small-cell lung cancer cell lines. Anticancer Res 19: 5423-5428, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 5423-5428
    • Bahadori, H.R.1    Rocha-Lima, C.M.2    Green, M.R.3    Safa, A.R.4
  • 17
    • 0035131918 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer with a combination of docetaxel, gemcitabine and granulocyte colony-stimulating factor: A phase II study of the Greek Cooperative Group for Pancreatic Cancer
    • Stathopoulos GP, Mavroudis D, Tsavaris N, Kouroussis C, Aravantinos G, Agelakis S, Kakolyris S, Rigatos SK, Karabekios S and Georgoulias V: Treatment of pancreatic cancer with a combination of docetaxel, gemcitabine and granulocyte colony-stimulating factor: a phase II study of the Greek Cooperative Group for Pancreatic Cancer. Ann Oncol 12: 101-103, 2001.
    • (2001) Ann Oncol , vol.12 , pp. 101-103
    • Stathopoulos, G.P.1    Mavroudis, D.2    Tsavaris, N.3    Kouroussis, C.4    Aravantinos, G.5    Agelakis, S.6    Kakolyris, S.7    Rigatos, S.K.8    Karabekios, S.9    Georgoulias, V.10
  • 19
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma. Eastern Cooperative Oncology Group Trial E 2297
    • Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DJ and Benson AB: Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma. Eastern Cooperative Oncology Group Trial E 2297. J Clin Oncol 20: 3270-3275, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3    Kugler, J.W.4    Haller, D.J.5    Benson, A.B.6
  • 20
    • 0037208590 scopus 로고    scopus 로고
    • Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma: A phase I/II trial
    • Hess V, Salzberg M, Borner M, Marant R, Roth AD, Ludwig C and Hermann R: Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma: a phase I/II trial. J Clin Oncol 21: 66-68, 2003.
    • (2003) J Clin Oncol , vol.21 , pp. 66-68
    • Hess, V.1    Salzberg, M.2    Borner, M.3    Marant, R.4    Roth, A.D.5    Ludwig, C.6    Hermann, R.7
  • 26
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine, results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha-Lima CM, Green MR, Rotche R, Miller WH Jr, Jeffrey GM, Cisar LA, Morganti A, Orlando N, Gruia G and Miller LL: Irinotecan plus gemcitabine, results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 22: 3776-3783, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3783
    • Rocha-Lima, C.M.1    Green, M.R.2    Rotche, R.3    Miller Jr, W.H.4    Jeffrey, G.M.5    Cisar, L.A.6    Morganti, A.7    Orlando, N.8    Gruia, G.9    Miller, L.L.10
  • 33
    • 42549120343 scopus 로고    scopus 로고
    • Poplin E, Lewy DE, Berlin J, Rothenberg M, Cella D, Mitchell E, Alberts S and Benson A: Phase III trial of gemcitabine 30 minute infusion vs. gemcitabine fixed dose rate infusion versus gemcitabine + oxaliplatin. J Clin Oncol 24: 180s, 2006 (Abstract 4004).
    • Poplin E, Lewy DE, Berlin J, Rothenberg M, Cella D, Mitchell E, Alberts S and Benson A: Phase III trial of gemcitabine 30 minute infusion vs. gemcitabine fixed dose rate infusion versus gemcitabine + oxaliplatin. J Clin Oncol 24: 180s, 2006 (Abstract 4004).
  • 35
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo-control, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first-line therapy in patients with advanced pancreatic cancer
    • Bramhall SR, Schulz J, Nemunaitis J, Brown PD, Baillet M and Buckels JA: A double-blind placebo-control, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first-line therapy in patients with advanced pancreatic cancer. Br J Cancer 87: 161-167, 2002.
    • (2002) Br J Cancer , vol.87 , pp. 161-167
    • Bramhall, S.R.1    Schulz, J.2    Nemunaitis, J.3    Brown, P.D.4    Baillet, M.5    Buckels, J.A.6
  • 37
    • 0034767957 scopus 로고    scopus 로고
    • Cancer burden in the year 2000, the global picture
    • Parkin DM, Bray FI and Devessa SS: Cancer burden in the year 2000, the global picture. Eur J Cancer 37: s4-s66, 2001.
    • (2001) Eur J Cancer , vol.37
    • Parkin, D.M.1    Bray, F.I.2    Devessa, S.S.3
  • 40
    • 33747146789 scopus 로고    scopus 로고
    • Lapatinib, a novel EGFR/HER2 tyrosine kinase inhibitor for cancer
    • Johnson SR and Leary A: Lapatinib, a novel EGFR/HER2 tyrosine kinase inhibitor for cancer. Drugs Today 42: 441-453, 2006.
    • (2006) Drugs Today , vol.42 , pp. 441-453
    • Johnson, S.R.1    Leary, A.2
  • 41
    • 0036531923 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer
    • Baker CH, Solorzano CC and Fidler IJ: Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Res 62: 1996-2003, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1996-2003
    • Baker, C.H.1    Solorzano, C.C.2    Fidler, I.J.3
  • 42
    • 27944456879 scopus 로고    scopus 로고
    • Investigating the potential of bevacizumab in other indications: Metastatic renal cell, non-small-cell lung, pancreatic and breast cancer
    • De Gramont A and Van Cutsem E: Investigating the potential of bevacizumab in other indications: metastatic renal cell, non-small-cell lung, pancreatic and breast cancer. Oncology 69: 46-56, 2005.
    • (2005) Oncology , vol.69 , pp. 46-56
    • De Gramont, A.1    Van Cutsem, E.2
  • 44
    • 28544451083 scopus 로고    scopus 로고
    • Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model
    • Yokoi K, Sasaki T, Bucana CD, Fan D, Baker CH, Kitadai Y, Kuwai T. Abbruzzese JL and Fidler IJ: Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. Cancer Res 65: 10371-10380, 2005.
    • (2005) Cancer Res , vol.65 , pp. 10371-10380
    • Yokoi, K.1    Sasaki, T.2    Bucana, C.D.3    Fan, D.4    Baker, C.H.5    Kitadai, Y.6    Kuwai, T.7    Abbruzzese, J.L.8    Fidler, I.J.9
  • 45
    • 0033199017 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroid anti-inflammatory drugs
    • Molina MA, Sitja-Arnau M, Lemoine MG, Frazier ML and Sinicrope FA: Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroid anti-inflammatory drugs. Cancer Res 59: 4356-4362, 1999.
    • (1999) Cancer Res , vol.59 , pp. 4356-4362
    • Molina, M.A.1    Sitja-Arnau, M.2    Lemoine, M.G.3    Frazier, M.L.4    Sinicrope, F.A.5
  • 47
    • 13644267274 scopus 로고    scopus 로고
    • Molecular regulation of pancreatic stellate cell function
    • Jasner R: Molecular regulation of pancreatic stellate cell function. Molecular Cancer 3: 1-8, 2004.
    • (2004) Molecular Cancer , vol.3 , pp. 1-8
    • Jasner, R.1
  • 49
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidyl inositol 3 kinase AKT pathway in human cancer
    • Vivanco I and Sawyers CL: The phosphatidyl inositol 3 kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 50
    • 33751162384 scopus 로고    scopus 로고
    • Therapeutic targets: MTOR and related pathways
    • Daucey JE: Therapeutic targets: mTOR and related pathways. Cancer Biol Ther 5: 1065-1073, 2006.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1065-1073
    • Daucey, J.E.1
  • 53
    • 0034235955 scopus 로고    scopus 로고
    • Epidermal growth factor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenografts in nude mice
    • Overholser JP, Prewett MC, Hooper AT, Waksal HW and Hicklin DJ: Epidermal growth factor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenografts in nude mice. Cancer 89: 74-82, 2000.
    • (2000) Cancer , vol.89 , pp. 74-82
    • Overholser, J.P.1    Prewett, M.C.2    Hooper, A.T.3    Waksal, H.W.4    Hicklin, D.J.5
  • 54
    • 0038016686 scopus 로고    scopus 로고
    • Differential responses by pancreatic carcinoma cell lines to prolonged exposure to erbitux (IMC-C225) anti-EGFR antibody
    • Huang ZQ, Buchsmaum DJ, Raisch KP, Bonner JA, Bland KI and Vickers SM: Differential responses by pancreatic carcinoma cell lines to prolonged exposure to erbitux (IMC-C225) anti-EGFR antibody. J Surg Res 111: 274-283, 2003.
    • (2003) J Surg Res , vol.111 , pp. 274-283
    • Huang, Z.Q.1    Buchsmaum, D.J.2    Raisch, K.P.3    Bonner, J.A.4    Bland, K.I.5    Vickers, S.M.6
  • 55
    • 4344590997 scopus 로고    scopus 로고
    • Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II trial
    • Xiong HQ, Rosenberg A, Lobuglio A, Schmidt W, Wolff RA, Deutsch J, Needle M and Abbruzzese JL: Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II trial. J Clin Oncol 22: 2610-2616, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 2610-2616
    • Xiong, H.Q.1    Rosenberg, A.2    Lobuglio, A.3    Schmidt, W.4    Wolff, R.A.5    Deutsch, J.6    Needle, M.7    Abbruzzese, J.L.8
  • 56
    • 0037389850 scopus 로고    scopus 로고
    • Expression of molecular targets for tyrosine kinase receptor antagonists in malignant endocrine pancreatic tumors
    • Fjällskog MLH, Lejonklou MH, Öberg KE, Eriksson BK and Janson ET: Expression of molecular targets for tyrosine kinase receptor antagonists in malignant endocrine pancreatic tumors. Clin Cancer Res 9: 1469-1473, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 1469-1473
    • Fjällskog, M.L.H.1    Lejonklou, M.H.2    Öberg, K.E.3    Eriksson, B.K.4    Janson, E.T.5
  • 58
    • 6044241807 scopus 로고    scopus 로고
    • The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: Poor prognosis in patients with pancreatic ductal adenocarcinoma
    • Veda S, Ogata S, Tsuda H, Kawarabayashi N, Kimura M, Sugiura Y, Tamai S, Matsubara O, Hatsuse K and Mochizuki H: The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: poor prognosis in patients with pancreatic ductal adenocarcinoma. Pancreas 29: E1-E8, 2004.
    • (2004) Pancreas , vol.29
    • Veda, S.1    Ogata, S.2    Tsuda, H.3    Kawarabayashi, N.4    Kimura, M.5    Sugiura, Y.6    Tamai, S.7    Matsubara, O.8    Hatsuse, K.9    Mochizuki, H.10
  • 59
    • 0034212763 scopus 로고    scopus 로고
    • Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
    • Bruns CJ, Solorzano CC, Harbison MT, Ozawa S, Tsan R, Fan D, Abbruzzese J, Traxler P, Buchdunger E, Radinsky R and Fidler IJ: Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res 60: 2926-2935, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2926-2935
    • Bruns, C.J.1    Solorzano, C.C.2    Harbison, M.T.3    Ozawa, S.4    Tsan, R.5    Fan, D.6    Abbruzzese, J.7    Traxler, P.8    Buchdunger, E.9    Radinsky, R.10    Fidler, I.J.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.